The network for 'cellular response to arsenic containing substance' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cellular response to arsenic containing substance

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides.

Homo sapiens
Name Description Probability Func Analog Organism
MAP2K4 mitogen-activated protein kinase kinase 4 0.771
MAPK8 mitogen-activated protein kinase 8 0.577
MAPK14 mitogen-activated protein kinase 14 0.441
ATF2 activating transcription factor 2 0.413
JUN jun proto-oncogene 0.390
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 0.314
SNTA1 syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component) 0.256
DUSP1 dual specificity phosphatase 1 0.204
ARRB1 arrestin, beta 1 0.186
ZFP36L1 zinc finger protein 36, C3H type-like 1 0.134
MAP2K6 mitogen-activated protein kinase kinase 6 0.076
MAPK1 mitogen-activated protein kinase 1 0.071
GRPEL1 GrpE-like 1, mitochondrial (E. coli) 0.068
DUSP7 dual specificity phosphatase 7 0.068
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.060
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 0.052
DUSP3 dual specificity phosphatase 3 0.048
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 0.038
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 0.035
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium) 0.029
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 0.028
GAB1 GRB2-associated binding protein 1 0.027
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.024
DUSP9 dual specificity phosphatase 9 0.023
CPNE6 copine VI (neuronal) 0.022
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 0.020
XPO7 exportin 7 0.019
FLNB filamin B, beta 0.019
DUSP16 dual specificity phosphatase 16 0.018
RANBP9 RAN binding protein 9 0.017
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 0.017
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4 0.017
CEP110 centrosomal protein 110kDa 0.016
MAP3K1 mitogen-activated protein kinase kinase kinase 1 0.016
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.015
GLA galactosidase, alpha 0.014
MAP2K3 mitogen-activated protein kinase kinase 3 0.013
MKNK2 MAP kinase interacting serine/threonine kinase 2 0.013
PLXNB1 plexin B1 0.013
OBSL1 obscurin-like 1 0.013
CUL7 cullin 7 0.012
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.012
MAP2K7 mitogen-activated protein kinase kinase 7 0.012
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 0.012
UTY ubiquitously transcribed tetratricopeptide repeat gene, Y-linked 0.012
ZBTB25 zinc finger and BTB domain containing 25 0.012
MKNK1 MAP kinase interacting serine/threonine kinase 1 0.011
EIF4A2 eukaryotic translation initiation factor 4A2 0.011
SS18 synovial sarcoma translocation, chromosome 18 0.011
LIMK1 LIM domain kinase 1 0.011
SPRY2 sprouty homolog 2 (Drosophila) 0.011
PKN1 protein kinase N1 0.010
KDM4B lysine (K)-specific demethylase 4B 0.010
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
p38b CG7393 gene product from transcript CG7393-RA 0.523
Dlic Dynein light intermediate chain 0.386
S6k RPS6-p70-protein kinase 0.169
Ric Ras which interacts with Calmodulin 0.132
BG4 CG12297 gene product from transcript CG12297-RA 0.131
janA janus A 0.112
whd withered 0.096
Mt2 Methyltransferase 2 0.084
Tpi Triose phosphate isomerase 0.079
cert ceramide transfer protein 0.073
CG2118 CG2118 gene product from transcript CG2118-RB 0.069
MTF-1 Metal response element-binding Transcription Factor-1 0.064
InR Insulin-like receptor 0.063
Rel Relish 0.059
lic licorne 0.052
Atg7 Autophagy-specific gene 7 0.051
Hr96 Hormone receptor-like in 96 0.050
Prosbeta3 Proteasome beta3 subunit 0.050
msn misshapen 0.048
Atf-2 Activating transcription factor-2 0.045
puc puckered 0.040
Jra Jun-related antigen 0.037
Dip3 Dorsal interacting protein 3 0.035
Mekk1 CG7717 gene product from transcript CG7717-RB 0.029
Mnt CG13316 gene product from transcript CG13316-RD 0.025
Trxr-1 Thioredoxin reductase-1 0.024
MP1 Melanization Protease 1 0.022
rin rasputin 0.022
Sp7 Serine protease 7 0.019
syd sunday driver 0.015
alph alphabet 0.015
NLaz Neural Lazarillo 0.014
CG5224 CG5224 gene product from transcript CG5224-RA 0.014
hep hemipterous 0.014
Dsor1 Downstream of raf1 0.014
PGRP-LE Peptidoglycan recognition protein LE 0.013
Eip75B Ecdysone-induced protein 75B 0.012
CG2100 CG2100 gene product from transcript CG2100-RB 0.012
CG1316 CG1316 gene product from transcript CG1316-RA 0.012
Sod Superoxide dismutase 0.012
AGO2 Argonaute 2 0.012
Mnn1 Menin 1 0.012
chico CG5686 gene product from transcript CG5686-RB 0.012
CG32486 CG32486 gene product from transcript CG32486-RD 0.011
GstE3 Glutathione S transferase E3 0.010
chic chickadee 0.010
Sdc Syndecan 0.010
Hsp27 Heat shock protein 27 0.010
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Mus musculus
Name Description Probability Func Analog Organism
Atf2 activating transcription factor 2 1.000
Mapk14 mitogen-activated protein kinase 14 1.000
Mapkapk2 MAP kinase-activated protein kinase 2 0.995
Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 0.995
Mapk1 mitogen-activated protein kinase 1 0.981
Mknk1 MAP kinase-interacting serine/threonine kinase 1 0.875
Klc1 kinesin light chain 1 0.827
Pten phosphatase and tensin homolog 0.781
Usp9x ubiquitin specific peptidase 9, X chromosome 0.763
Elavl1 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) 0.670
Mapk11 mitogen-activated protein kinase 11 0.647
Mapk9 mitogen-activated protein kinase 9 0.621
Neurl1a neuralized homolog 1A (Drosophila) 0.542
Map2k3 mitogen-activated protein kinase kinase 3 0.509
Prkce protein kinase C, epsilon 0.501
Pea15a phosphoprotein enriched in astrocytes 15A 0.453
Mapk3 mitogen-activated protein kinase 3 0.451
Gsta4 glutathione S-transferase, alpha 4 0.292
Stim2 stromal interaction molecule 2 0.276
Mapk8 mitogen-activated protein kinase 8 0.275
Slc40a1 solute carrier family 40 (iron-regulated transporter), member 1 0.271
Mknk2 MAP kinase-interacting serine/threonine kinase 2 0.235
Gripap1 GRIP1 associated protein 1 0.232
Wdr26 WD repeat domain 26 0.202
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.178
Zfand5 zinc finger, AN1-type domain 5 0.164
Ifrd1 interferon-related developmental regulator 1 0.154
Canx calnexin 0.152
C1qbp complement component 1, q subcomponent binding protein 0.145
Sqstm1 sequestosome 1 0.142
Tle1 transducin-like enhancer of split 1, homolog of Drosophila E(spl) 0.133
Kpna1 karyopherin (importin) alpha 1 0.131
Camk2b calcium/calmodulin-dependent protein kinase II, beta 0.127
Stk39 serine/threonine kinase 39, STE20/SPS1 homolog (yeast) 0.122
Dusp6 dual specificity phosphatase 6 0.119
Il6 interleukin 6 0.112
Met met proto-oncogene 0.112
Homer1 homer homolog 1 (Drosophila) 0.104
Pcyt1a phosphate cytidylyltransferase 1, choline, alpha isoform 0.090
Impad1 inositol monophosphatase domain containing 1 0.089
Tmem30a transmembrane protein 30A 0.089
Cpeb4 cytoplasmic polyadenylation element binding protein 4 0.087
Cpeb2 cytoplasmic polyadenylation element binding protein 2 0.087
Lin7c lin-7 homolog C (C. elegans) 0.087
Cab39 calcium binding protein 39 0.087
Kif1b kinesin family member 1B 0.085
Capn1 calpain 1 0.083
Nprl3 nitrogen permease regulator-like 3 (S. cerevisiae) 0.083
Spna1 spectrin alpha 1 0.080
Atp2a2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 0.078
Acsl4 acyl-CoA synthetase long-chain family member 4 0.078
Eea1 early endosome antigen 1 0.078
Mib1 mindbomb homolog 1 (Drosophila) 0.077
Atp5b ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit 0.073
Tob1 transducer of ErbB-2.1 0.072
Mdm2 transformed mouse 3T3 cell double minute 2 0.070
Rab10 RAB10, member RAS oncogene family 0.065
Pdpk1 3-phosphoinositide dependent protein kinase 1 0.064
Skil SKI-like 0.062
Mapk6 mitogen-activated protein kinase 6 0.056
Myf5 myogenic factor 5 0.055
Myo6 myosin VI 0.054
Serinc1 serine incorporator 1 0.053
Stim1 stromal interaction molecule 1 0.053
Eif5 eukaryotic translation initiation factor 5 0.053
Mapk12 mitogen-activated protein kinase 12 0.051
Etnk1 ethanolamine kinase 1 0.049
Adcy9 adenylate cyclase 9 0.049
1810013L24Rik RIKEN cDNA 1810013L24 gene 0.048
Trp53 transformation related protein 53 0.048
Aplp2 amyloid beta (A4) precursor-like protein 2 0.046
Rnf11 ring finger protein 11 0.046
Mtap2 microtubule-associated protein 2 0.044
Sh3bgrl3 SH3 domain binding glutamic acid-rich protein-like 3 0.043
Jun Jun oncogene 0.043
Cftr cystic fibrosis transmembrane conductance regulator homolog 0.040
Samd8 sterile alpha motif domain containing 8 0.040
Mt2 metallothionein 2 0.039
Kif21a kinesin family member 21A 0.038
Errfi1 ERBB receptor feedback inhibitor 1 0.038
Phka1 phosphorylase kinase alpha 1 0.037
Prkar2a protein kinase, cAMP dependent regulatory, type II alpha 0.036
Mt1 metallothionein 1 0.036
Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I) 0.036
Sms spermine synthase 0.035
Dsg4 desmoglein 4 0.035
Rora RAR-related orphan receptor alpha 0.034
Prkaa2 protein kinase, AMP-activated, alpha 2 catalytic subunit 0.034
Gadd45g growth arrest and DNA-damage-inducible 45 gamma 0.033
Kctd9 potassium channel tetramerisation domain containing 9 0.033
Mtmr1 myotubularin related protein 1 0.032
Lcn2 lipocalin 2 0.032
Rps6ka5 ribosomal protein S6 kinase, polypeptide 5 0.032
Epn2 epsin 2 0.032
Fbxw7 F-box and WD-40 domain protein 7 0.031
Ate1 arginyltransferase 1 0.031
Dnajb9 DnaJ (Hsp40) homolog, subfamily B, member 9 0.031
Optn optineurin 0.030
Usp12 ubiquitin specific peptidase 12 0.030
1500003O03Rik RIKEN cDNA 1500003O03 gene 0.030
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
HAL5 Hal5p 0.067
RPN4 Rpn4p 0.060
PSP2 Psp2p 0.050
MIG2 Mig2p 0.049
MIG3 Mig3p 0.042
YKR075C hypothetical protein 0.037
HXT3 Hxt3p 0.035
CAT8 Cat8p 0.026
VID24 Vid24p 0.025
MIG1 Mig1p 0.023
CTI6 Cti6p 0.020
MPT5 Mpt5p 0.020
OTU1 Otu1p 0.020
UBX4 Ubx4p 0.018
ROX1 Rox1p 0.017
SWI1 Swi1p 0.017
MOT3 Mot3p 0.017
YLR297W hypothetical protein 0.016
HDA2 Hda2p 0.016
MSN4 Msn4p 0.015
MSG5 Msg5p 0.015
TPO2 Tpo2p 0.015
BSD2 Bsd2p 0.015
NVJ1 Nvj1p 0.014
GAT2 Gat2p 0.014
GAL7 Gal7p 0.014
KSS1 Kss1p 0.013
MBR1 Mbr1p 0.013
FAA2 Faa2p 0.013
RGS2 Rgs2p 0.013
YPL014W hypothetical protein 0.012
PHM8 Phm8p 0.012
KIC1 Kic1p 0.011
SFL1 Sfl1p 0.011
TOF2 Tof2p 0.011
IRC23 Irc23p 0.011
VHS1 Vhs1p 0.011
STE5 Ste5p 0.011
POG1 Pog1p 0.010