IMP
Process View
The network for 'cellular response to vitamin d' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
cellular response to vitamin d
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin D stimulus.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| RXRA | retinoid X receptor, alpha | 0.837 | |
| PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | 0.731 | |
| NCOR2 | nuclear receptor corepressor 2 | 0.698 | |
| RARA | retinoic acid receptor, alpha | 0.672 | |
| IK | IK cytokine, down-regulator of HLA II | 0.478 | |
| NCOR1 | nuclear receptor corepressor 1 | 0.218 | |
| LATS2 | LATS, large tumor suppressor, homolog 2 (Drosophila) | 0.129 | |
| FN1 | fibronectin 1 | 0.121 | |
| EP300 | E1A binding protein p300 | 0.102 | |
| HNF4A | hepatocyte nuclear factor 4, alpha | 0.086 | |
| NCOA1 | nuclear receptor coactivator 1 | 0.080 | |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.078 | |
| FHL2 | four and a half LIM domains 2 | 0.060 | |
| HR | hairless homolog (mouse) | 0.050 | |
| MED25 | mediator complex subunit 25 | 0.047 | |
| TOP1 | topoisomerase (DNA) I | 0.042 | |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.037 | |
| ESR1 | estrogen receptor 1 | 0.023 | |
| ENG | endoglin | 0.022 | |
| ZNF830 | zinc finger protein 830 | 0.020 | |
| ESR2 | estrogen receptor 2 (ER beta) | 0.020 | |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.017 | |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.015 | |
| KDM1A | lysine (K)-specific demethylase 1A | 0.013 | |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.012 | |
| CD9 | CD9 molecule | 0.012 | |
| AQR | aquarius homolog (mouse) | 0.012 | |
| JUB | jub, ajuba homolog (Xenopus laevis) | 0.011 | |
| PPARA | peroxisome proliferator-activated receptor alpha | 0.011 | |
| CWC15 | CWC15 spliceosome-associated protein homolog (S. cerevisiae) | 0.011 | |
| CDC5L | CDC5 cell division cycle 5-like (S. pombe) | 0.011 | |
| NOTCH1 | notch 1 | 0.011 | |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor | 0.011 | |
| THRA | thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian) | 0.010 | |
| SART1 | squamous cell carcinoma antigen recognized by T cells | 0.010 |
Loading network...
Mus musculus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Ptgs2 | prostaglandin-endoperoxide synthase 2 | 0.790 | |
| Vdr | vitamin D receptor | 0.771 | |
| Bglap | bone gamma carboxyglutamate protein | 0.754 | |
| Lep | leptin | 0.494 | |
| Cbx5 | chromobox homolog 5 (Drosophila HP1a) | 0.319 | |
| Kl | klotho | 0.272 | |
| Smad3 | MAD homolog 3 (Drosophila) | 0.267 | |
| Kras | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.173 | |
| Esr1 | estrogen receptor 1 (alpha) | 0.171 | |
| Lepr | leptin receptor | 0.156 | |
| Slc34a3 | solute carrier family 34 (sodium phosphate), member 3 | 0.142 | |
| Nos2 | nitric oxide synthase 2, inducible | 0.137 | |
| Sfrp2 | secreted frizzled-related protein 2 | 0.130 | |
| Il10 | interleukin 10 | 0.127 | |
| Tgfb1 | transforming growth factor, beta 1 | 0.122 | |
| Tlr4 | toll-like receptor 4 | 0.111 | |
| Hif1a | hypoxia inducible factor 1, alpha subunit | 0.110 | |
| Vhl | von Hippel-Lindau tumor suppressor | 0.091 | |
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.086 | |
| Fgfr2 | fibroblast growth factor receptor 2 | 0.081 | |
| Nos1 | nitric oxide synthase 1, neuronal | 0.081 | |
| Mmp9 | matrix metallopeptidase 9 | 0.074 | |
| Il6 | interleukin 6 | 0.064 | |
| Slc12a1 | solute carrier family 12, member 1 | 0.062 | |
| Fgf23 | fibroblast growth factor 23 | 0.061 | |
| Tnf | tumor necrosis factor | 0.060 | |
| Csf1 | colony stimulating factor 1 (macrophage) | 0.056 | |
| Cbx1 | chromobox homolog 1 (Drosophila HP1 beta) | 0.053 | |
| Crim1 | cysteine rich transmembrane BMP regulator 1 (chordin like) | 0.053 | |
| Col1a1 | collagen, type I, alpha 1 | 0.053 | |
| Ren1 | renin 1 structural | 0.052 | |
| Vav2 | vav 2 oncogene | 0.052 | |
| Phex | phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets) | 0.049 | |
| Ar | androgen receptor | 0.047 | |
| Nr3c1 | nuclear receptor subfamily 3, group C, member 1 | 0.045 | |
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.044 | |
| Notch2 | Notch gene homolog 2 (Drosophila) | 0.042 | |
| Apc | adenomatosis polyposis coli | 0.039 | |
| Wnt5a | wingless-related MMTV integration site 5A | 0.039 | |
| Smad4 | MAD homolog 4 (Drosophila) | 0.038 | |
| Ccr2 | chemokine (C-C motif) receptor 2 | 0.036 | |
| Slc34a1 | solute carrier family 34 (sodium phosphate), member 1 | 0.035 | |
| Fam20c | family with sequence similarity 20, member C | 0.035 | |
| Tnfrsf1b | tumor necrosis factor receptor superfamily, member 1b | 0.032 | |
| Cav1 | caveolin 1, caveolae protein | 0.031 | |
| Pthlh | parathyroid hormone-like peptide | 0.030 | |
| Gnas | GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus | 0.029 | |
| Fas | Fas (TNF receptor superfamily member 6) | 0.027 | |
| Efs | embryonal Fyn-associated substrate | 0.026 | |
| Ncoa6 | nuclear receptor coactivator 6 | 0.026 | |
| Tlr2 | toll-like receptor 2 | 0.024 | |
| Braf | Braf transforming gene | 0.024 | |
| Erbb2 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 0.023 | |
| Bcl2 | B-cell leukemia/lymphoma 2 | 0.023 | |
| Ccl2 | chemokine (C-C motif) ligand 2 | 0.023 | |
| Cdkn1a | cyclin-dependent kinase inhibitor 1A (P21) | 0.022 | |
| Tnfsf11 | tumor necrosis factor (ligand) superfamily, member 11 | 0.022 | |
| Nf1 | neurofibromatosis 1 | 0.020 | |
| Nr2f2 | nuclear receptor subfamily 2, group F, member 2 | 0.019 | |
| Kitl | kit ligand | 0.018 | |
| Spp1 | secreted phosphoprotein 1 | 0.018 | |
| Snai1 | snail homolog 1 (Drosophila) | 0.018 | |
| Stat3 | signal transducer and activator of transcription 3 | 0.018 | |
| Vegfa | vascular endothelial growth factor A | 0.018 | |
| Bptf | bromodomain PHD finger transcription factor | 0.017 | |
| Pparg | peroxisome proliferator activated receptor gamma | 0.017 | |
| Dlg2 | discs, large homolog 2 (Drosophila) | 0.017 | |
| Kat2a | K(lysine) acetyltransferase 2A | 0.017 | |
| Cd44 | CD44 antigen | 0.017 | |
| Vav3 | vav 3 oncogene | 0.016 | |
| Ptk2 | PTK2 protein tyrosine kinase 2 | 0.015 | |
| Pcdh18 | protocadherin 18 | 0.015 | |
| Srrt | serrate RNA effector molecule homolog (Arabidopsis) | 0.015 | |
| Prkci | protein kinase C, iota | 0.014 | |
| Fzd7 | frizzled homolog 7 (Drosophila) | 0.014 | |
| Ano6 | anoctamin 6 | 0.014 | |
| Hist1h3g | histone cluster 1, H3g | 0.014 | |
| Agtr1a | angiotensin II receptor, type 1a | 0.014 | |
| Cdh11 | cadherin 11 | 0.014 | |
| U2af2 | U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2 | 0.013 | |
| Zmym2 | zinc finger, MYM-type 2 | 0.013 | |
| Adam17 | a disintegrin and metallopeptidase domain 17 | 0.013 | |
| Dicer1 | Dicer1, Dcr-1 homolog (Drosophila) | 0.013 | |
| Gpc3 | glypican 3 | 0.013 | |
| Apoe | apolipoprotein E | 0.012 | |
| Ifng | interferon gamma | 0.012 | |
| Cdkn1b | cyclin-dependent kinase inhibitor 1B | 0.012 | |
| Abl1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.012 | |
| Ace | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 | 0.012 | |
| Atp6v1a | ATPase, H+ transporting, lysosomal V1 subunit A | 0.012 | |
| Mdm2 | transformed mouse 3T3 cell double minute 2 | 0.012 | |
| Tnfrsf1a | tumor necrosis factor receptor superfamily, member 1a | 0.012 | |
| Chaf1a | chromatin assembly factor 1, subunit A (p150) | 0.012 | |
| Psen1 | presenilin 1 | 0.011 | |
| Itga3 | integrin alpha 3 | 0.011 | |
| Efnb2 | ephrin B2 | 0.011 | |
| Wasl | Wiskott-Aldrich syndrome-like (human) | 0.011 | |
| Wt1 | Wilms tumor 1 homolog | 0.010 | |
| Tcfcp2l1 | transcription factor CP2-like 1 | 0.010 | |
| Fzd1 | frizzled homolog 1 (Drosophila) | 0.010 |
Loading network...
Rattus norvegicus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| LOC293989 | cytochrome P450-like | 0.116 | |
| Cyp3a18 | cytochrome P450, family 3, subfamily a, polypeptide 18 | 0.079 | |
| Cyp2c13 | cytochrome P450, family 2, subfamily c, polypeptide 13 | 0.049 | |
| Ptprh | protein tyrosine phosphatase, receptor type, H | 0.048 | |
| Cps1 | carbamoyl-phosphate synthetase 1 | 0.046 | |
| Dio1 | deiodinase, iodothyronine, type I | 0.046 | |
| Igfals | insulin-like growth factor binding protein, acid labile subunit | 0.041 | |
| Sult2a2 | sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 2 | 0.041 | |
| Gja5 | gap junction protein, alpha 5 | 0.039 | |
| Ugt2b5 | UDP glucuronosyltransferase 2 family, polypeptide B5 | 0.035 | |
| Sult2a1 | sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 | 0.031 | |
| Omd | osteomodulin | 0.030 | |
| Cyp3a2 | cytochrome P450, family 3, subfamily a, polypeptide 2 | 0.029 | |
| Sult1e1 | sulfotransferase family 1E, estrogen-preferring, member 1 | 0.028 | |
| Clca4 | chloride channel accessory 4 | 0.024 | |
| Cyp3a23/3a1 | cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 1 | 0.023 | |
| Ugt2b | UDP glycosyltransferase 2 family, polypeptide B | 0.023 | |
| Muc13 | mucin 13, cell surface associated | 0.023 | |
| LOC305103 | cell surface glycoprotein gp42 | 0.023 | |
| Ces1c | carboxylesterase 1C | 0.021 | |
| Cyp4f4 | cytochrome P450, family 4, subfamily f, polypeptide 4 | 0.021 | |
| Acot12 | acyl-CoA thioesterase 12 | 0.021 | |
| Ugt2b1 | UDP glucuronosyltransferase 2 family, polypeptide B1 | 0.021 | |
| Cga | glycoprotein hormones, alpha polypeptide | 0.020 | |
| Tnf | tumor necrosis factor (TNF superfamily, member 2) | 0.019 | |
| Naaladl1 | N-acetylated alpha-linked acidic dipeptidase-like 1 | 0.019 | |
| Nlrp6 | NLR family, pyrin domain containing 6 | 0.019 | |
| Vdr | vitamin D (1,25- dihydroxyvitamin D3) receptor | 0.018 | |
| Hist1h2ba | histone cluster 1, H2ba | 0.018 | |
| Calcb | calcitonin-related polypeptide, beta | 0.018 | |
| Htr2a | 5-hydroxytryptamine (serotonin) receptor 2A | 0.017 | |
| Slc8a1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | 0.017 | |
| Mos | Moloney sarcoma oncogene | 0.017 | |
| Cyp2c11 | cytochrome P450, subfamily 2, polypeptide 11 | 0.017 | |
| Mug1 | murinoglobulin 1 | 0.016 | |
| Rup2 | urinary protein 2 | 0.016 | |
| Ceacam10 | carcinoembryonic antigen-related cell adhesion molecule 10 | 0.016 | |
| Lphn1 | latrophilin 1 | 0.016 | |
| Il8ra | interleukin 8 receptor, alpha | 0.016 | |
| Cdh17 | cadherin 17 | 0.015 | |
| Vim | vimentin | 0.014 | |
| Phex | phosphate regulating endopeptidase homolog, X-linked | 0.014 | |
| Actr2 | ARP2 actin-related protein 2 homolog (yeast) | 0.014 | |
| Cd79b | Cd79b molecule, immunoglobulin-associated beta | 0.014 | |
| Pou3f2 | POU class 3 homeobox 2 | 0.014 | |
| Sval1 | seminal vesicle antigen-like 1 | 0.013 | |
| Fstl1 | follistatin-like 1 | 0.013 | |
| Dnase1l3 | deoxyribonuclease 1-like 3 | 0.013 | |
| Gulo | gulonolactone (L-) oxidase | 0.013 | |
| Ugt2b37 | UDP-glucuronosyltransferase 2 family, member 37 | 0.013 | |
| Tnmd | tenomodulin | 0.012 | |
| Ptgfr | prostaglandin F receptor | 0.012 | |
| Sult1b1 | sulfotransferase family, cytosolic, 1B, member 1 | 0.012 | |
| Acsm2 | acyl-CoA synthetase medium-chain family member 2 | 0.012 | |
| Il2ra | interleukin 2 receptor, alpha | 0.012 | |
| Ehhadh | enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase | 0.012 | |
| Cyp4f1 | cytochrome P450, family 4, subfamily f, polypeptide 1 | 0.012 | |
| Col10a1 | collagen, type X, alpha 1 | 0.011 | |
| Unc13c | unc-13 homolog C (C. elegans) | 0.011 | |
| Ugt8 | UDP glycosyltransferase 8 | 0.011 | |
| Serpina3m | serine (or cysteine) proteinase inhibitor, clade A, member 3M | 0.011 | |
| G6pc | glucose-6-phosphatase, catalytic subunit | 0.011 | |
| Selp | selectin P | 0.011 | |
| Cxcl6 | chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) | 0.011 | |
| Pip | prolactin induced protein | 0.011 | |
| Obp3 | alpha-2u globulin PGCL4 | 0.011 | |
| Il1a | interleukin 1 alpha | 0.011 | |
| Mmp3 | matrix metallopeptidase 3 | 0.011 | |
| Htr2b | 5-hydroxytryptamine (serotonin) receptor 2B | 0.010 | |
| Fmo3 | flavin containing monooxygenase 3 | 0.010 | |
| Gabrp | gamma-aminobutyric acid (GABA-A) receptor, pi | 0.010 | |
| Csn1s2a | casein alpha s2-like A | 0.010 | |
| Mmp7 | matrix metallopeptidase 7 | 0.010 |