IMP
Process View
The network for 'response to interferon beta' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
response to interferon beta
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-beta stimulus. Interferon-beta is a type I interferon.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| IRF9 | interferon regulatory factor 9 | 0.987 | |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.943 | |
| STAT2 | signal transducer and activator of transcription 2, 113kDa | 0.759 | |
| PLSCR1 | phospholipid scramblase 1 | 0.703 | |
| IFITM1 | interferon induced transmembrane protein 1 (9-27) | 0.694 | |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.606 | |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.576 | |
| IFITM3 | interferon induced transmembrane protein 3 (1-8U) | 0.556 | |
| IFITM2 | interferon induced transmembrane protein 2 (1-8D) | 0.554 | |
| NMI | N-myc (and STAT) interactor | 0.470 | |
| IFNAR2 | interferon (alpha, beta and omega) receptor 2 | 0.426 | |
| JAK1 | Janus kinase 1 | 0.120 | |
| IRF1 | interferon regulatory factor 1 | 0.106 | |
| TMEM173 | transmembrane protein 173 | 0.098 | |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.081 | |
| GBP4 | guanylate binding protein 4 | 0.073 | |
| PML | promyelocytic leukemia | 0.071 | |
| IL4R | interleukin 4 receptor | 0.070 | |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.070 | |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 | 0.066 | |
| TRIM21 | tripartite motif containing 21 | 0.057 | |
| TRIM22 | tripartite motif containing 22 | 0.049 | |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.047 | |
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 | 0.046 | |
| GBP1 | guanylate binding protein 1, interferon-inducible | 0.044 | |
| JAK2 | Janus kinase 2 | 0.041 | |
| SP110 | SP110 nuclear body protein | 0.038 | |
| KAT2B | K(lysine) acetyltransferase 2B | 0.031 | |
| SP1 | Sp1 transcription factor | 0.029 | |
| IL12RB2 | interleukin 12 receptor, beta 2 | 0.029 | |
| TFG | TRK-fused gene | 0.028 | |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.028 | |
| IL15RA | interleukin 15 receptor, alpha | 0.028 | |
| IFI44L | interferon-induced protein 44-like | 0.027 | |
| EPSTI1 | epithelial stromal interaction 1 (breast) | 0.026 | |
| IL2RB | interleukin 2 receptor, beta | 0.026 | |
| IFI6 | interferon, alpha-inducible protein 6 | 0.025 | |
| ISG15 | ISG15 ubiquitin-like modifier | 0.024 | |
| EFEMP2 | EGF containing fibulin-like extracellular matrix protein 2 | 0.023 | |
| MX1 | myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) | 0.023 | |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | 0.022 | |
| INSR | insulin receptor | 0.021 | |
| PIAS4 | protein inhibitor of activated STAT, 4 | 0.021 | |
| APOL6 | apolipoprotein L, 6 | 0.021 | |
| HTT | huntingtin | 0.019 | |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.018 | |
| HLA-E | major histocompatibility complex, class I, E | 0.018 | |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.018 | |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.017 | |
| STAP2 | signal transducing adaptor family member 2 | 0.016 | |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha | 0.016 | |
| SP100 | SP100 nuclear antigen | 0.015 | |
| RTP4 | receptor (chemosensory) transporter protein 4 | 0.015 | |
| MYD88 | myeloid differentiation primary response gene (88) | 0.015 | |
| NKAP | NFKB activating protein | 0.014 | |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.014 | |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 0.013 | |
| CREBBP | CREB binding protein | 0.013 | |
| IFI44 | interferon-induced protein 44 | 0.013 | |
| MX2 | myxovirus (influenza virus) resistance 2 (mouse) | 0.013 | |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.013 | |
| DTX3L | deltex 3-like (Drosophila) | 0.012 | |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.012 | |
| BST2 | bone marrow stromal cell antigen 2 | 0.010 |
Loading network...
Mus musculus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Iigp1 | interferon inducible GTPase 1 | 0.996 | |
| Igtp | interferon gamma induced GTPase | 0.989 | |
| Gbp3 | guanylate binding protein 3 | 0.969 | |
| Ifi203 | interferon activated gene 203 | 0.927 | |
| Mndal | myeloid nuclear differentiation antigen like | 0.921 | |
| Gbp7 | guanylate binding protein 7 | 0.913 | |
| Gbp2 | guanylate binding protein 2 | 0.861 | |
| Ifit1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.788 | |
| Irgm1 | immunity-related GTPase family M member 1 | 0.754 | |
| Tgtp2 | T-cell specific GTPase 2 | 0.724 | |
| Casp4 | caspase 4, apoptosis-related cysteine peptidase | 0.645 | |
| Irgm2 | immunity-related GTPase family M member 2 | 0.639 | |
| Ifitm3 | interferon induced transmembrane protein 3 | 0.592 | |
| Irf9 | interferon regulatory factor 9 | 0.561 | |
| Ifih1 | interferon induced with helicase C domain 1 | 0.524 | |
| Ifit3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.459 | |
| Trim21 | tripartite motif-containing 21 | 0.442 | |
| Irf7 | interferon regulatory factor 7 | 0.434 | |
| Gbp10 | guanylate-binding protein 10 | 0.431 | |
| Usp18 | ubiquitin specific peptidase 18 | 0.429 | |
| Ifi47 | interferon gamma inducible protein 47 | 0.399 | |
| Rtp4 | receptor transporter protein 4 | 0.365 | |
| Casp1 | caspase 1 | 0.364 | |
| Psmb8 | proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7) | 0.343 | |
| Mnda | myeloid cell nuclear differentiation antigen | 0.336 | |
| Cxcl10 | chemokine (C-X-C motif) ligand 10 | 0.335 | |
| Pycard | PYD and CARD domain containing | 0.318 | |
| Gbp6 | guanylate binding protein 6 | 0.308 | |
| Isg15 | ISG15 ubiquitin-like modifier | 0.242 | |
| Ly6a | lymphocyte antigen 6 complex, locus A | 0.220 | |
| Nmi | N-myc (and STAT) interactor | 0.200 | |
| Ifit2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.178 | |
| Ms4a4c | membrane-spanning 4-domains, subfamily A, member 4C | 0.172 | |
| Oasl2 | 2'-5' oligoadenylate synthetase-like 2 | 0.158 | |
| Trim30a | tripartite motif-containing 30A | 0.147 | |
| Parp9 | poly (ADP-ribose) polymerase family, member 9 | 0.136 | |
| Ifi204 | interferon activated gene 204 | 0.099 | |
| Rsad2 | radical S-adenosyl methionine domain containing 2 | 0.098 | |
| Gvin1 | GTPase, very large interferon inducible 1 | 0.083 | |
| Ifi44 | interferon-induced protein 44 | 0.080 | |
| AI607873 | expressed sequence AI607873 | 0.066 | |
| Sp100 | nuclear antigen Sp100 | 0.063 | |
| Lgals3bp | lectin, galactoside-binding, soluble, 3 binding protein | 0.062 | |
| Slfn8 | schlafen 8 | 0.062 | |
| D14Ertd668e | DNA segment, Chr 14, ERATO Doi 668, expressed | 0.048 | |
| Trim30d | tripartite motif-containing 30D | 0.046 | |
| H2-Q7 | histocompatibility 2, Q region locus 7 | 0.044 | |
| Casp12 | caspase 12 | 0.041 | |
| Cd274 | CD274 antigen | 0.036 | |
| Tnfsf10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.036 | |
| Parp14 | poly (ADP-ribose) polymerase family, member 14 | 0.035 | |
| Mx1 | myxovirus (influenza virus) resistance 1 | 0.031 | |
| Cxcl9 | chemokine (C-X-C motif) ligand 9 | 0.029 | |
| Herc6 | hect domain and RLD 6 | 0.029 | |
| Ifitm2 | interferon induced transmembrane protein 2 | 0.029 | |
| C1ra | complement component 1, r subcomponent A | 0.028 | |
| AW112010 | expressed sequence AW112010 | 0.028 | |
| Gbp8 | guanylate-binding protein 8 | 0.026 | |
| Serpinb9 | serine (or cysteine) peptidase inhibitor, clade B, member 9 | 0.024 | |
| Psmb9 | proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2) | 0.023 | |
| Cmpk2 | cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial | 0.022 | |
| Il1a | interleukin 1 alpha | 0.020 | |
| H2-K1 | histocompatibility 2, K1, K region | 0.019 | |
| Ube2l6 | ubiquitin-conjugating enzyme E2L 6 | 0.019 | |
| Gbp9 | guanylate-binding protein 9 | 0.019 | |
| Ifnar2 | interferon (alpha and beta) receptor 2 | 0.018 | |
| Uba7 | ubiquitin-like modifier activating enzyme 7 | 0.018 | |
| Serpina3g | serine (or cysteine) peptidase inhibitor, clade A, member 3G | 0.017 | |
| Mx2 | myxovirus (influenza virus) resistance 2 | 0.016 | |
| Birc3 | baculoviral IAP repeat-containing 3 | 0.016 | |
| Slfn4 | schlafen 4 | 0.014 | |
| Tmem176b | transmembrane protein 176B | 0.014 | |
| Ifi35 | interferon-induced protein 35 | 0.014 | |
| BC006779 | cDNA sequence BC006779 | 0.014 | |
| Ms4a6b | membrane-spanning 4-domains, subfamily A, member 6B | 0.014 | |
| Ms4a4d | membrane-spanning 4-domains, subfamily A, member 4D | 0.013 | |
| Samhd1 | SAM domain and HD domain, 1 | 0.013 | |
| Tmem176a | transmembrane protein 176A | 0.013 | |
| C920025E04Rik | RIKEN cDNA C920025E04 gene | 0.012 | |
| Oas1b | 2'-5' oligoadenylate synthetase 1B | 0.012 | |
| Dtx3l | deltex 3-like (Drosophila) | 0.012 | |
| Ccl2 | chemokine (C-C motif) ligand 2 | 0.012 | |
| S100a9 | S100 calcium binding protein A9 (calgranulin B) | 0.011 | |
| Gimap4 | GTPase, IMAP family member 4 | 0.011 | |
| Zbp1 | Z-DNA binding protein 1 | 0.011 | |
| C3 | complement component 3 | 0.011 | |
| Eif2ak2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.011 | |
| Cp | ceruloplasmin | 0.010 | |
| Ifitm1 | interferon induced transmembrane protein 1 | 0.010 | |
| H2-T10 | histocompatibility 2, T region locus 10 | 0.010 | |
| Tlr6 | toll-like receptor 6 | 0.010 |
Loading network...
Rattus norvegicus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Ifitm2 | interferon induced transmembrane protein 2 | 0.938 | |
| Ifitm3 | interferon induced transmembrane protein 3 | 0.572 | |
| Ifitm1 | interferon induced transmembrane protein 1 | 0.240 | |
| Tagln2 | transgelin 2 | 0.094 | |
| Mgp | matrix Gla protein | 0.086 | |
| Serping1 | serine (or cysteine) peptidase inhibitor, clade G, member 1 | 0.073 | |
| Gbp2 | guanylate binding protein 2 | 0.072 | |
| S100a6 | S100 calcium binding protein A6 | 0.067 | |
| Tmem176b | transmembrane protein 176B | 0.056 | |
| C1s | complement component 1, s subcomponent | 0.044 | |
| Timp1 | TIMP metallopeptidase inhibitor 1 | 0.040 | |
| Ifit3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.039 | |
| Psmb8 | proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7) | 0.038 | |
| Dcn | decorin | 0.034 | |
| Rtp4 | receptor (chemosensory) transporter protein 4 | 0.031 | |
| Rarres2 | retinoic acid receptor responder (tazarotene induced) 2 | 0.026 | |
| S100a11 | S100 calcium binding protein A11 (calizzarin) | 0.026 | |
| Usp18 | ubiquitin specific peptidase 18 | 0.025 | |
| Oasl | 2'-5'-oligoadenylate synthetase-like | 0.020 | |
| Lgals3bp | lectin, galactoside-binding, soluble, 3 binding protein | 0.019 | |
| Irf7 | interferon regulatory factor 7 | 0.018 | |
| Lgals1 | lectin, galactoside-binding, soluble, 1 | 0.017 | |
| Ifi204 | interferon activated gene 204 | 0.014 | |
| Isg15 | ISG15 ubiquitin-like modifier | 0.014 | |
| Ifi27l2b | interferon, alpha-inducible protein 27 like 2B | 0.011 | |
| Ltbr | lymphotoxin beta receptor (TNFR superfamily, member 3) | 0.010 |