The network for 'membrane budding' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

membrane budding

The evagination of a membrane, resulting in formation of a vesicle.

Homo sapiens
Name Description Probability Func Analog Organism
PDCD6IP programmed cell death 6 interacting protein 0.999
TSG101 tumor susceptibility gene 101 0.998
EPS15 epidermal growth factor receptor pathway substrate 15 0.997
S100A6 S100 calcium binding protein A6 0.989
PTPN23 protein tyrosine phosphatase, non-receptor type 23 0.986
PDCD6 programmed cell death 6 0.982
SEC23A Sec23 homolog A (S. cerevisiae) 0.974
CUL3 cullin 3 0.963
S100A9 S100 calcium binding protein A9 0.958
STON2 stonin 2 0.954
S100A8 S100 calcium binding protein A8 0.861
LGALS1 lectin, galactoside-binding, soluble, 1 0.849
DNM2 dynamin 2 0.835
S100A10 S100 calcium binding protein A10 0.814
ANXA2 annexin A2 0.810
SH3KBP1 SH3-domain kinase binding protein 1 0.752
S100A11 S100 calcium binding protein A11 0.735
SOS1 son of sevenless homolog 1 (Drosophila) 0.727
ANXA1 annexin A1 0.695
ITSN1 intersectin 1 (SH3 domain protein) 0.688
ARF4 ADP-ribosylation factor 4 0.642
DAAM1 dishevelled associated activator of morphogenesis 1 0.599
IQGAP1 IQ motif containing GTPase activating protein 1 0.546
S100B S100 calcium binding protein B 0.501
COPB1 coatomer protein complex, subunit beta 1 0.480
FASLG Fas ligand (TNF superfamily, member 6) 0.466
CLTC clathrin, heavy chain (Hc) 0.457
USP54 ubiquitin specific peptidase 54 0.439
PACSIN1 protein kinase C and casein kinase substrate in neurons 1 0.402
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.388
SEC24A SEC24 family, member A (S. cerevisiae) 0.373
CHMP1A chromatin modifying protein 1A 0.370
SEC31A SEC31 homolog A (S. cerevisiae) 0.355
DAPK1 death-associated protein kinase 1 0.335
S100A4 S100 calcium binding protein A4 0.313
ARCN1 archain 1 0.236
AGFG1 ArfGAP with FG repeats 1 0.235
S100A1 S100 calcium binding protein A1 0.233
NFE2L2 nuclear factor (erythroid-derived 2)-like 2 0.226
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 0.224
NBR1 neighbor of BRCA1 gene 1 0.221
SQLE squalene epoxidase 0.219
CHMP4B chromatin modifying protein 4B 0.213
WIPF1 WAS/WASL interacting protein family, member 1 0.211
OCRL oculocerebrorenal syndrome of Lowe 0.196
USP8 ubiquitin specific peptidase 8 0.194
ANXA7 annexin A7 0.168
KBTBD7 kelch repeat and BTB (POZ) domain containing 7 0.165
GORASP2 golgi reassembly stacking protein 2, 55kDa 0.158
GOLGA2 golgin A2 0.152
KRT15 keratin 15 0.151
SURF4 surfeit 4 0.150
GOLGA5 golgin A5 0.149
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 0.148
CAST calpastatin 0.143
SEC24B SEC24 family, member B (S. cerevisiae) 0.131
ARFGAP2 ADP-ribosylation factor GTPase activating protein 2 0.120
DNM1 dynamin 1 0.117
AREG amphiregulin 0.116
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 0.115
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 0.114
BCAR1 breast cancer anti-estrogen resistance 1 0.110
WNK4 WNK lysine deficient protein kinase 4 0.109
S100A2 S100 calcium binding protein A2 0.104
ABI1 abl-interactor 1 0.104
AP1M1 adaptor-related protein complex 1, mu 1 subunit 0.103
RNF111 ring finger protein 111 0.100
BTBD10 BTB (POZ) domain containing 10 0.099
CHMP1B chromatin modifying protein 1B 0.091
RAB2A RAB2A, member RAS oncogene family 0.091
SEC13 SEC13 homolog (S. cerevisiae) 0.090
IDI1 isopentenyl-diphosphate delta isomerase 1 0.088
SPOP speckle-type POZ protein 0.087
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme 0.086
TMED7 transmembrane emp24 protein transport domain containing 7 0.085
SC4MOL sterol-C4-methyl oxidase-like 0.084
STAMBP STAM binding protein 0.084
SMN1 survival of motor neuron 1, telomeric 0.082
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.072
CHMP2B chromatin modifying protein 2B 0.071
SH3GL1 SH3-domain GRB2-like 1 0.065
GORAB golgin, RAB6-interacting 0.062
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 0.059
WASL Wiskott-Aldrich syndrome-like 0.058
VPS24 vacuolar protein sorting 24 homolog (S. cerevisiae) 0.058
ANXA5 annexin A5 0.057
STARD4 StAR-related lipid transfer (START) domain containing 4 0.056
S100P S100 calcium binding protein P 0.056
TNK2 tyrosine kinase, non-receptor, 2 0.054
KLC1 kinesin light chain 1 0.054
RNF11 ring finger protein 11 0.053
SEC24D SEC24 family, member D (S. cerevisiae) 0.052
RAB5A RAB5A, member RAS oncogene family 0.051
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 0.051
CYFIP1 cytoplasmic FMR1 interacting protein 1 0.051
FCHO2 FCH domain only 2 0.051
AP2A1 adaptor-related protein complex 2, alpha 1 subunit 0.050
SNX9 sorting nexin 9 0.049
KRT19 keratin 19 0.049
MYO6 myosin VI 0.049
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
hgrs-1 Protein HGRS-1 0.042
CELE_Y47G6A.18 Protein Y47G6A.18 0.037
itsn-1 Protein ITSN-1 0.032
ykt-6 Protein YKT-6 0.030
unc-60 Protein UNC-60 0.029
C33H5.17 Protein C33H5.17 0.027
unc-108 Protein UNC-108 0.026
kin-4 Protein KIN-4 0.025
CELE_F23C8.6 Protein F23C8.6 0.023
lst-4 Protein LST-4 0.022
alx-1 Protein ALX-1 0.022
lig-4 Protein LIG-4 0.021
npp-7 Protein NPP-7 0.020
CELE_B0238.9 Protein B0238.9 0.020
D2013.6 Protein D2013.6 0.019
gsp-1 Protein GSP-1 0.019
CELE_F55D12.5 Protein F55D12.5 0.018
C28H8.4 Protein C28H8.4 0.017
F37C4.5 Protein F37C4.5 0.017
F47G9.1 Protein F47G9.1 0.016
rer-1 Protein RER-1 0.016
ttr-2 Protein TTR-2 0.015
unc-11 Protein UNC-11 0.015
pqn-83 Protein PQN-83 0.015
C45G9.7 Protein C45G9.7 0.015
bath-40 Protein BATH-40 0.014
Y74C10AL.2 Protein Y74C10AL.2 0.014
CELE_Y110A2AR.3 Protein Y110A2AR.3 0.014
vps-26 Protein VPS-26 0.014
unc-32 Protein UNC-32 0.014
F29B9.8 Protein F29B9.8 0.014
F15G9.1 Protein F15G9.1 0.013
F42G9.6 Protein F42G9.6 0.013
CELE_T23B5.3 Protein T23B5.3 0.013
prmt-5 Protein PRMT-5 0.013
arx-1 Protein ARX-1 0.013
ZK686.3 Protein ZK686.3 0.013
tag-335 Protein TAG-335 0.013
Y48G8AL.7 Protein Y48G8AL.7 0.013
Y37E3.1 Protein Y37E3.1 0.012
Y41D4A.5 Protein Y41D4A.5 0.012
pcf-11 Protein PCF-11 0.012
clh-6 Protein CLH-6 0.012
hpo-22 Protein HPO-22 0.012
klp-7 Protein KLP-7 0.012
ubc-14 Protein UBC-14 0.012
fis-2 Protein FIS-2 0.012
C18H9.3 Protein C18H9.3 0.011
F59E12.9 Protein F59E12.9 0.011
H14A12.5 Protein H14A12.5 0.011
cdc-14 Protein CDC-14 0.011
hum-1 Protein HUM-1 0.011
C10B5.3 Protein C10B5.3 0.011
oxi-1 Protein OXI-1 0.011
pup-2 Protein PUP-2 0.011
ubxn-1 Protein UBXN-1 0.011
goa-1 Protein GOA-1 0.011
rop-1 Protein ROP-1 0.011
B0361.8 Protein B0361.8 0.011
CELE_Y52B11A.3 Protein Y52B11A.3 0.011
Y18H1A.2 Protein Y18H1A.2 0.010
CELE_Y105E8B.6 Protein Y105E8B.6 0.010
png-1 Protein PNG-1 0.010
F34D10.4 Protein F34D10.4 0.010
R148.2 Protein R148.2 0.010
ile-2 Protein ILE-2 0.010
exo-1 Protein EXO-1 0.010
pod-1 Protein POD-1 0.010
lin-36 Protein LIN-36 0.010
rab-10 Protein RAB-10 0.010
panl-3 Protein PANL-3 0.010
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
shrb shrub 0.879
vps24 Charged multivesicular body protein 3 0.773
CG10103 CG10103 gene product from transcript CG10103-RA 0.731
Chmp1 CG4108 gene product from transcript CG4108-RA 0.628
vps2 CG14542 gene product from transcript CG14542-RA 0.493
CG6259 CG6259 gene product from transcript CG6259-RA 0.359
CHMP2B Charged multivesicular body protein 2b 0.266
Rab5 Rab-protein 5 0.238
Vps25 Vacuolar protein sorting 25 0.223
bai baiser 0.174
Hrs Hepatocyte growth factor regulated tyrosine kinase substrate 0.164
lsn larsen 0.148
Rab7 Rab-protein 7 0.090
endoA endophilin A 0.089
Vps28 Vacuolar protein sorting 28 0.079
p24-1 p24-related-1 0.071
Sop2 Suppressor of profilin 2 0.068
Dap160 Dynamin associated protein 160 0.064
Chc Clathrin heavy chain 0.063
CHOp24 CG3564 gene product from transcript CG3564-RA 0.060
Osbp Oxysterol binding protein 0.056
Stam Signal transducing adaptor molecule 0.055
comt comatose 0.049
CG8230 CG8230 gene product from transcript CG8230-RA 0.046
nwk nervous wreck 0.046
Syb Synaptobrevin 0.044
TSG101 tumor suppressor protein 101 0.044
Vps4 Vacuolar protein sorting 4 0.041
GM130 CG11061 gene product from transcript CG11061-RB 0.040
par-1 CG8201 gene product from transcript CG8201-RA 0.039
sds22 CG5851 gene product from transcript CG5851-RA 0.039
sqh spaghetti squash 0.038
Ube3a Ubiquitin protein ligase E3A 0.037
synj synaptojanin 0.034
hiw highwire 0.034
PP2A-B' CG7913 gene product from transcript CG7913-RK 0.034
syd sunday driver 0.034
Klp68D Kinesin-like protein at 68D 0.033
lap like-AP180 0.032
Rab6 Rab-protein 6 0.032
twf twinfilin 0.030
par-6 CG5884 gene product from transcript CG5884-RA 0.030
CG4101 CG4101 gene product from transcript CG4101-RA 0.030
Liprin-alpha CG11199 gene product from transcript CG11199-RB 0.029
Bap Beta Adaptin 0.028
CG3573 CG3573 gene product from transcript CG3573-RA 0.028
CG15012 CG15012 gene product from transcript CG15012-RB 0.028
CG11526 CG11526 gene product from transcript CG11526-RB 0.027
lqf liquid facets 0.027
CG1115 CG1115 gene product from transcript CG1115-RA 0.026
G-oalpha47A G protein oalpha 47A 0.026
NKAIN Na,K-ATPase Interacting 0.026
spir spire 0.025
ALiX ALG-2 interacting protein X 0.025
betaCop beta-coatomer protein 0.024
Nmnat Nicotinamide mononucleotide adenylyltransferase 0.024
loqs loquacious 0.024
Pi3K59F Phosphotidylinositol 3 kinase 59F 0.024
beta'Cop beta'-coatomer protein 0.023
CG3356 CG3356 gene product from transcript CG3356-RA 0.023
mib2 mind bomb 2 0.023
CG7967 CG7967 gene product from transcript CG7967-RA 0.022
CG2224 CG2224 gene product from transcript CG2224-RA 0.022
ari-1 ariadne 0.022
sei seizure 0.021
slik Sterile20-like kinase 0.021
sm smooth 0.020
Syx7 Syntaxin 7 0.020
KrT95D Krueppel target at 95D 0.019
Arf84F ADP ribosylation factor 84F 0.019
l(2)k16918 lethal (2) k16918 0.019
CG14650 CG14650 gene product from transcript CG14650-RA 0.019
Vps20 Vacuolar protein sorting 20 0.018
Gie novel GTPase indispensable for equal segregation of chromosomes 0.018
Cnx99A Calnexin 99A 0.017
Mo25 CG4083 gene product from transcript CG4083-RA 0.017
SH3PX1 CG6757 gene product from transcript CG6757-RA 0.017
capu cappuccino 0.017
MED9 Mediator complex subunit 9 0.017
CG10916 CG10916 gene product from transcript CG10916-RA 0.017
CG9063 CG9063 gene product from transcript CG9063-RA 0.017
Rab8 Rab-protein 8 0.016
Fkbp13 CG9847 gene product from transcript CG9847-RC 0.016
CG7023 CG7023 gene product from transcript CG7023-RB 0.016
fry furry 0.016
eIF-1A Eukaryotic initiation factor 1A 0.016
CaMKII Calcium/calmodulin-dependent protein kinase II 0.016
Rbcn-3A Rabconnectin-3A 0.016
unc-104 CG8566 gene product from transcript CG8566-RB 0.016
Pp1-87B Protein phosphatase 1 at 87B 0.016
Jra Jun-related antigen 0.015
Vha100-1 CG1709 gene product from transcript CG1709-RF 0.015
Mlc-c Myosin light chain cytoplasmic 0.015
mop myopic 0.015
CG11286 CG11286 gene product from transcript CG11286-RA 0.015
CG9523 CG9523 gene product from transcript CG9523-RA 0.015
Manf Mesencephalic astrocyte-derived neurotrophic factor 0.015
Tango14 Transport and Golgi organization 14 0.015
l(3)L1231 lethal (3) L1231 0.015
spict spichthyin 0.015
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Itsn1 intersectin 1 (SH3 domain protein 1A) 0.093
Atp6v1a ATPase, H+ transporting, lysosomal V1 subunit A 0.014
Ap2a2 adaptor protein complex AP-2, alpha 2 subunit 0.012
Ssr3 signal sequence receptor, gamma 0.012
Copg coatomer protein complex, subunit gamma 0.010
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Ap2b1 adaptor-related protein complex 2, beta 1 subunit 0.011
Ap2a1 adaptor-related protein complex 2, alpha 1 subunit 0.010
Gak cyclin G associated kinase 0.010
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
SEC23 Sec23p 0.983
SEC24 Sec24p 0.979
SEC13 Sec13p 0.951
SEC16 Sec16p 0.913
SEC31 Sec31p 0.866
ERV25 Erv25p 0.841
SAR1 Sar1p 0.707
SFB3 Sfb3p 0.613
PAN1 Pan1p 0.561
EMP24 Emp24p 0.420
SFB2 Sfb2p 0.347
ENT2 Ent2p 0.323
GRH1 Grh1p 0.321
DID2 Did2p 0.307
SNF7 Snf7p 0.285
BRO1 Bro1p 0.239
SEC21 Sec21p 0.178
ERP4 Erp4p 0.177
PMI40 Pmi40p 0.165
SLA2 Sla2p 0.163
APM2 Apm2p 0.125
IST1 Ist1p 0.110
VPS4 Vps4p 0.101
ABP1 Abp1p 0.097
MCD4 Mcd4p 0.091
VPS36 Vps36p 0.090
RER1 Rer1p 0.084
AKL1 Akl1p 0.083
SEC22 Sec22p 0.081
ERP1 Erp1p 0.078
YCK3 Yck3p 0.071
ERP5 Erp5p 0.063
YPR091C hypothetical protein 0.062
VPS24 Vps24p 0.059
SEC26 Sec26p 0.044
ERV29 Erv29p 0.041
GAL83 Gal83p 0.039
SED4 Sed4p 0.036
VRP1 Vrp1p 0.035
ERP3 Erp3p 0.034
STP22 Stp22p 0.033
ROD1 Rod1p 0.032
FPK1 Fpk1p 0.031
CHC1 Chc1p 0.030
YJL055W hypothetical protein 0.030
SEC7 Sec7p 0.028
CPT1 Cpt1p 0.028
MYO5 Myo5p 0.028
SEC61 Sec61p 0.027
HAL5 Hal5p 0.027
ENA5 Ena5p 0.027
UGO1 Ugo1p 0.027
ACK1 Ack1p 0.026
YKT6 Ykt6p 0.026
ARK1 Ark1p 0.025
YLR283W hypothetical protein 0.025
SRD1 Srd1p 0.024
LHS1 Lhs1p 0.024
YLR264C-A hypothetical protein 0.024
RET2 Ret2p 0.024
APS1 Aps1p 0.024
DSE3 Dse3p 0.024
SOV1 Sov1p 0.024
CLP1 Clp1p 0.024
YMR124W hypothetical protein 0.023
HLJ1 Hlj1p 0.023
ARG8 Arg8p 0.023
ARP10 Arp10p 0.023
SUB1 Sub1p 0.023
RIM13 Rim13p 0.023
END3 End3p 0.023
CRZ1 Crz1p 0.023
AGE1 Age1p 0.022
LST7 Lst7p 0.022
CUP1-1 Cup1-1p 0.022
SEC12 Sec12p 0.021
YOL087C hypothetical protein 0.021
YER128W hypothetical protein 0.021
LEU2 Leu2p 0.021
VPS38 Vps38p 0.021
HYP2 Hyp2p 0.020
YOL038C-A hypothetical protein 0.020
INP53 Inp53p 0.019
SWC7 Swc7p 0.019
MER1 Mer1p 0.019
PSD2 Psd2p 0.019
MOT2 Mot2p 0.019
SEC27 Sec27p 0.019
MSC7 Msc7p 0.018
DNM1 Dnm1p 0.018
GYL1 Gyl1p 0.018
LAP3 Lap3p 0.018
YLR162W hypothetical protein 0.018
RHO1 Rho1p 0.018
BCH2 Bch2p 0.018
MDL2 Mdl2p 0.018
YIR035C hypothetical protein 0.017
YPL077C hypothetical protein 0.017
ARF2 Arf2p 0.017
YGR122W hypothetical protein 0.017