IMP
Process View
The network for 'regulation of cholesterol efflux' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
regulation of cholesterol efflux
Any process that modulates the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 0.774 | |
| C1QA | complement component 1, q subcomponent, A chain | 0.701 | |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.387 | |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta | 0.199 | |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.149 | |
| C1QC | complement component 1, q subcomponent, C chain | 0.095 | |
| APBB1 | amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) | 0.093 | |
| RELB | v-rel reticuloendotheliosis viral oncogene homolog B | 0.087 | |
| REL | v-rel reticuloendotheliosis viral oncogene homolog (avian) | 0.074 | |
| BCL3 | B-cell CLL/lymphoma 3 | 0.065 | |
| C1QB | complement component 1, q subcomponent, B chain | 0.062 | |
| A2M | alpha-2-macroglobulin | 0.060 | |
| CREBBP | CREB binding protein | 0.050 | |
| RRAGC | Ras-related GTP binding C | 0.048 | |
| SNTB2 | syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) | 0.042 | |
| RELA | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.040 | |
| APOC1 | apolipoprotein C-I | 0.040 | |
| LAMTOR2 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 | 0.040 | |
| HP | haptoglobin | 0.037 | |
| C7orf59 | chromosome 7 open reading frame 59 | 0.031 | |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 0.029 | |
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta | 0.026 | |
| TIRAP | toll-interleukin 1 receptor (TIR) domain containing adaptor protein | 0.026 | |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.025 | |
| MED15 | mediator complex subunit 15 | 0.020 | |
| EP300 | E1A binding protein p300 | 0.016 | |
| PELI3 | pellino homolog 3 (Drosophila) | 0.016 | |
| HNF4A | hepatocyte nuclear factor 4, alpha | 0.015 | |
| SMPD1 | sphingomyelin phosphodiesterase 1, acid lysosomal | 0.013 | |
| FOXO3 | forkhead box O3 | 0.011 | |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | 0.010 | |
| SMO | smoothened homolog (Drosophila) | 0.010 | |
| CHUK | conserved helix-loop-helix ubiquitous kinase | 0.010 |
Loading network...
Mus musculus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Fgfr2 | fibroblast growth factor receptor 2 | 0.731 | |
| Abca1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.713 | |
| Npc1 | Niemann Pick type C1 | 0.637 | |
| Apoe | apolipoprotein E | 0.541 | |
| Traf6 | TNF receptor-associated factor 6 | 0.402 | |
| Cebpa | CCAAT/enhancer binding protein (C/EBP), alpha | 0.322 | |
| Lyz2 | lysozyme 2 | 0.263 | |
| Relb | avian reticuloendotheliosis viral (v-rel) oncogene related B | 0.161 | |
| Mapk8ip1 | mitogen-activated protein kinase 8 interacting protein 1 | 0.126 | |
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.115 | |
| Lrp1 | low density lipoprotein receptor-related protein 1 | 0.096 | |
| Ldlr | low density lipoprotein receptor | 0.091 | |
| Abcg1 | ATP-binding cassette, sub-family G (WHITE), member 1 | 0.076 | |
| Lrp2 | low density lipoprotein receptor-related protein 2 | 0.066 | |
| Nr5a1 | nuclear receptor subfamily 5, group A, member 1 | 0.061 | |
| Pten | phosphatase and tensin homolog | 0.047 | |
| Nfkb1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 | 0.042 | |
| Kiss1 | KiSS-1 metastasis-suppressor | 0.042 | |
| Myd88 | myeloid differentiation primary response gene 88 | 0.038 | |
| Cebpb | CCAAT/enhancer binding protein (C/EBP), beta | 0.038 | |
| Rdh8 | retinol dehydrogenase 8 | 0.034 | |
| Kl | klotho | 0.030 | |
| Fgfr3 | fibroblast growth factor receptor 3 | 0.029 | |
| Tbx3 | T-box 3 | 0.028 | |
| Pkd1 | polycystic kidney disease 1 homolog | 0.027 | |
| Ndst1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 | 0.027 | |
| Klf15 | Kruppel-like factor 15 | 0.024 | |
| Axin1 | axin 1 | 0.024 | |
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.022 | |
| Foxa2 | forkhead box A2 | 0.021 | |
| Foxc1 | forkhead box C1 | 0.018 | |
| Pparg | peroxisome proliferator activated receptor gamma | 0.017 | |
| Gnrh1 | gonadotropin releasing hormone 1 | 0.016 | |
| Fgf9 | fibroblast growth factor 9 | 0.016 | |
| C3 | complement component 3 | 0.016 | |
| Sertad2 | SERTA domain containing 2 | 0.016 | |
| Notch2 | Notch gene homolog 2 (Drosophila) | 0.016 | |
| Ar | androgen receptor | 0.015 | |
| Arntl | aryl hydrocarbon receptor nuclear translocator-like | 0.015 | |
| Amhr2 | anti-Mullerian hormone type 2 receptor | 0.015 | |
| Pax2 | paired box gene 2 | 0.015 | |
| Pick1 | protein interacting with C kinase 1 | 0.014 | |
| Rxra | retinoid X receptor alpha | 0.014 | |
| Rela | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.013 | |
| Vangl2 | vang-like 2 (van gogh, Drosophila) | 0.013 | |
| Mertk | c-mer proto-oncogene tyrosine kinase | 0.013 | |
| Col4a3 | collagen, type IV, alpha 3 | 0.013 | |
| Col4a4 | collagen, type IV, alpha 4 | 0.013 | |
| Pthlh | parathyroid hormone-like peptide | 0.012 | |
| App | amyloid beta (A4) precursor protein | 0.012 | |
| Lepr | leptin receptor | 0.012 | |
| T | brachyury | 0.012 | |
| Smagp | small cell adhesion glycoprotein | 0.012 | |
| Pofut1 | protein O-fucosyltransferase 1 | 0.011 | |
| Bcl6 | B-cell leukemia/lymphoma 6 | 0.011 | |
| Clstn1 | calsyntenin 1 | 0.011 | |
| Dhcr7 | 7-dehydrocholesterol reductase | 0.011 | |
| Nr0b1 | nuclear receptor subfamily 0, group B, member 1 | 0.011 | |
| Oca2 | oculocutaneous albinism II | 0.010 | |
| Runx2 | runt related transcription factor 2 | 0.010 | |
| Ihh | Indian hedgehog | 0.010 | |
| Smpd3 | sphingomyelin phosphodiesterase 3, neutral | 0.010 | |
| Mapk8ip2 | mitogen-activated protein kinase 8 interacting protein 2 | 0.010 |