IMP
Process View
The network for 'regulation of angiotensin levels in blood' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
regulation of angiotensin levels in blood
The process that modulates the level of angiotensin in the blood by balancing the maturation of renin substrate to mature angiotensin and the catabolism of mature angiotensin.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Ctsb | cathepsin B | 0.843 | |
| Ngp | neutrophilic granule protein | 0.751 | |
| Ctsg | cathepsin G | 0.700 | |
| Fasl | Fas ligand (TNF superfamily, member 6) | 0.690 | |
| Ace | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 | 0.676 | |
| Agtr1a | angiotensin II receptor, type 1a | 0.636 | |
| Lamp2 | lysosomal-associated membrane protein 2 | 0.635 | |
| Gzmb | granzyme B | 0.632 | |
| Fcer1a | Fc receptor, IgE, high affinity I, alpha polypeptide | 0.618 | |
| Cpa3 | carboxypeptidase A3, mast cell | 0.608 | |
| Cidec | cell death-inducing DFFA-like effector c | 0.549 | |
| Cma1 | chymase 1, mast cell | 0.546 | |
| Mpo | myeloperoxidase | 0.453 | |
| Atp6v1c1 | ATPase, H+ transporting, lysosomal V1 subunit C1 | 0.433 | |
| Mmp10 | matrix metallopeptidase 10 | 0.365 | |
| Crim1 | cysteine rich transmembrane BMP regulator 1 (chordin like) | 0.364 | |
| Mcpt4 | mast cell protease 4 | 0.338 | |
| Elane | elastase, neutrophil expressed | 0.278 | |
| Lamp1 | lysosomal-associated membrane protein 1 | 0.262 | |
| Atp6ap1 | ATPase, H+ transporting, lysosomal accessory protein 1 | 0.225 | |
| Ncr1 | natural cytotoxicity triggering receptor 1 | 0.214 | |
| Prss2 | protease, serine, 2 | 0.209 | |
| Gzmf | granzyme F | 0.204 | |
| Klrg1 | killer cell lectin-like receptor subfamily G, member 1 | 0.201 | |
| Mup4 | major urinary protein 4 | 0.200 | |
| Asah1 | N-acylsphingosine amidohydrolase 1 | 0.200 | |
| Slc12a1 | solute carrier family 12, member 1 | 0.195 | |
| Il2rb | interleukin 2 receptor, beta chain | 0.189 | |
| Gzmc | granzyme C | 0.181 | |
| Klrk1 | killer cell lectin-like receptor subfamily K, member 1 | 0.181 | |
| Try5 | trypsin 5 | 0.176 | |
| Ctrl | chymotrypsin-like | 0.167 | |
| Gzma | granzyme A | 0.162 | |
| Xcl1 | chemokine (C motif) ligand 1 | 0.157 | |
| Zg16 | zymogen granule protein 16 | 0.156 | |
| Retn | resistin | 0.150 | |
| Mcpt8 | mast cell protease 8 | 0.150 | |
| Adipoq | adiponectin, C1Q and collagen domain containing | 0.150 | |
| Gp1ba | glycoprotein 1b, alpha polypeptide | 0.142 | |
| Cst7 | cystatin F (leukocystatin) | 0.133 | |
| Sva | seminal vesicle antigen | 0.128 | |
| Ccl8 | chemokine (C-C motif) ligand 8 | 0.124 | |
| Rnase1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.122 | |
| Il1rl1 | interleukin 1 receptor-like 1 | 0.120 | |
| Sh2d2a | SH2 domain protein 2A | 0.118 | |
| Atp6v0b | ATPase, H+ transporting, lysosomal V0 subunit B | 0.118 | |
| Egfr | epidermal growth factor receptor | 0.118 | |
| Nr3c2 | nuclear receptor subfamily 3, group C, member 2 | 0.115 | |
| Prg2 | proteoglycan 2, bone marrow | 0.114 | |
| Nkg7 | natural killer cell group 7 sequence | 0.112 | |
| Cd3e | CD3 antigen, epsilon polypeptide | 0.109 | |
| Klra9 | killer cell lectin-like receptor subfamily A, member 9 | 0.101 | |
| Myf6 | myogenic factor 6 | 0.101 | |
| Prl2b1 | prolactin family 2, subfamily b, member 1 | 0.094 | |
| Psap | prosaposin | 0.091 | |
| Mcpt1 | mast cell protease 1 | 0.090 | |
| Prol1 | proline rich, lacrimal 1 | 0.087 | |
| Cd7 | CD7 antigen | 0.086 | |
| Sfrp4 | secreted frizzled-related protein 4 | 0.084 | |
| Bdkrb2 | bradykinin receptor, beta 2 | 0.084 | |
| Gzme | granzyme E | 0.084 | |
| Ear2 | eosinophil-associated, ribonuclease A family, member 2 | 0.081 | |
| Nos2 | nitric oxide synthase 2, inducible | 0.080 | |
| Cyp2e1 | cytochrome P450, family 2, subfamily e, polypeptide 1 | 0.080 | |
| Ear11 | eosinophil-associated, ribonuclease A family, member 11 | 0.080 | |
| Klrc1 | killer cell lectin-like receptor subfamily C, member 1 | 0.078 | |
| Prl7a1 | prolactin family 7, subfamily a, member 1 | 0.078 | |
| Klrd1 | killer cell lectin-like receptor, subfamily D, member 1 | 0.077 | |
| Ltf | lactotransferrin | 0.077 | |
| Sdcbp | syndecan binding protein | 0.076 | |
| Gzmd | granzyme D | 0.075 | |
| Ms4a2 | membrane-spanning 4-domains, subfamily A, member 2 | 0.073 | |
| Ccl24 | chemokine (C-C motif) ligand 24 | 0.072 | |
| Grn | granulin | 0.070 | |
| Fcna | ficolin A | 0.070 | |
| Cd96 | CD96 antigen | 0.069 | |
| S100a9 | S100 calcium binding protein A9 (calgranulin B) | 0.069 | |
| Klk1b26 | kallikrein 1-related petidase b26 | 0.069 | |
| Ceacam12 | carcinoembryonic antigen-related cell adhesion molecule 12 | 0.068 | |
| Ermap | erythroblast membrane-associated protein | 0.066 | |
| Klk1b11 | kallikrein 1-related peptidase b11 | 0.066 | |
| Cma2 | chymase 2, mast cell | 0.065 | |
| Rhag | Rhesus blood group-associated A glycoprotein | 0.063 | |
| Ctsw | cathepsin W | 0.063 | |
| Akap4 | A kinase (PRKA) anchor protein 4 | 0.063 | |
| Smr3a | submaxillary gland androgen regulated protein 3A | 0.062 | |
| Tnfrsf9 | tumor necrosis factor receptor superfamily, member 9 | 0.062 | |
| Ms4a3 | membrane-spanning 4-domains, subfamily A, member 3 | 0.062 | |
| Gbp1 | guanylate binding protein 1 | 0.060 | |
| Il18rap | interleukin 18 receptor accessory protein | 0.059 | |
| Camp | cathelicidin antimicrobial peptide | 0.057 | |
| Enam | enamelin | 0.056 | |
| Fabp4 | fatty acid binding protein 4, adipocyte | 0.056 | |
| Krt27 | keratin 27 | 0.056 | |
| Reg3g | regenerating islet-derived 3 gamma | 0.055 | |
| Serpina12 | serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 | 0.055 | |
| Twsg1 | twisted gastrulation homolog 1 (Drosophila) | 0.055 | |
| Agt | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 0.053 | |
| LOC100504404 | h-2 class II histocompatibility antigen, E-K alpha chain-like | 0.053 | |
| Ctsl | cathepsin L | 0.053 |
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Homo sapiens
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| CTSA | cathepsin A | 0.334 | |
| PSAP | prosaposin | 0.124 | |
| GRN | granulin | 0.057 | |
| GNS | glucosamine (N-acetyl)-6-sulfatase | 0.028 | |
| CTSB | cathepsin B | 0.022 | |
| TPP1 | tripeptidyl peptidase I | 0.021 | |
| NEU1 | sialidase 1 (lysosomal sialidase) | 0.021 | |
| PLD3 | phospholipase D family, member 3 | 0.020 | |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.019 | |
| ITM2B | integral membrane protein 2B | 0.017 | |
| LAMP1 | lysosomal-associated membrane protein 1 | 0.017 | |
| ATP6AP1 | ATPase, H+ transporting, lysosomal accessory protein 1 | 0.014 | |
| ASAH1 | N-acylsphingosine amidohydrolase (acid ceramidase) 1 | 0.013 | |
| CST3 | cystatin C | 0.011 | |
| GAA | glucosidase, alpha; acid | 0.011 | |
| NUCB1 | nucleobindin 1 | 0.011 |
Loading network...
Rattus norvegicus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Grina | glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) | 0.079 | |
| Ctsb | cathepsin B | 0.020 | |
| Nucb1 | nucleobindin 1 | 0.018 | |
| Grn | granulin | 0.016 | |
| Ftl | ferritin, light polypeptide | 0.015 | |
| LOC24906 | RoBo-1 | 0.015 | |
| Cma1 | chymase 1, mast cell | 0.015 | |
| Atp6ap1 | ATPase, H+ transporting, lysosomal accessory protein 1 | 0.013 | |
| Ctsa | cathepsin A | 0.013 | |
| Capns1 | calpain, small subunit 1 | 0.012 | |
| P4hb | prolyl 4-hydroxylase, beta polypeptide | 0.012 | |
| Atp6v0c | ATPase, H+ transporting, lysosomal V0 subunit C | 0.011 | |
| Atp6v0d1 | ATPase, H+ transporting, lysosomal V0 subunit D1 | 0.011 |