The network for 'renal sodium ion transport' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

renal sodium ion transport

The directed movement of sodium ions (Na+) by the kidney.

Name Description Probability Func Analog Organism
Slc34a1 solute carrier family 34 (sodium phosphate), member 1 0.994
Slc12a1 solute carrier family 12, member 1 0.797
Atp2b2 ATPase, Ca++ transporting, plasma membrane 2 0.782
Kcne1 potassium voltage-gated channel, Isk-related subfamily, member 1 0.547
Kcnq1 potassium voltage-gated channel, subfamily Q, member 1 0.473
Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 0.442
Slc17a1 solute carrier family 17 (sodium phosphate), member 1 0.434
Esrrb estrogen related receptor, beta 0.413
Bsnd Bartter syndrome, infantile, with sensorineural deafness (Barttin) 0.397
Grid2 glutamate receptor, ionotropic, delta 2 0.354
Cckbr cholecystokinin B receptor 0.325
Srrm4 serine/arginine repetitive matrix 4 0.298
Slc5a2 solute carrier family 5 (sodium/glucose cotransporter), member 2 0.251
Stk39 serine/threonine kinase 39, STE20/SPS1 homolog (yeast) 0.247
Cntn2 contactin 2 0.206
Kcna4 potassium voltage-gated channel, shaker-related subfamily, member 4 0.198
Syt7 synaptotagmin VII 0.197
Kcnk3 potassium channel, subfamily K, member 3 0.189
Kcnj12 potassium inwardly-rectifying channel, subfamily J, member 12 0.186
Phkg1 phosphorylase kinase gamma 1 0.181
Ank1 ankyrin 1, erythroid 0.148
Srcin1 SRC kinase signaling inhibitor 1 0.146
Umod uromodulin 0.108
Phex phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets) 0.106
Kcnab3 potassium voltage-gated channel, shaker-related subfamily, beta member 3 0.105
Stx1b syntaxin 1B 0.103
Inadl InaD-like (Drosophila) 0.101
Crhr1 corticotropin releasing hormone receptor 1 0.098
Nfatc2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 0.094
Crhr2 corticotropin releasing hormone receptor 2 0.091
Slc22a8 solute carrier family 22 (organic anion transporter), member 8 0.091
Grxcr1 glutaredoxin, cysteine rich 1 0.090
Kcnj11 potassium inwardly rectifying channel, subfamily J, member 11 0.090
Rnf112 ring finger protein 112 0.089
Kcnj5 potassium inwardly-rectifying channel, subfamily J, member 5 0.088
Mmp24 matrix metallopeptidase 24 0.087
Mgat3 mannoside acetylglucosaminyltransferase 3 0.083
Slc12a5 solute carrier family 12, member 5 0.083
Nrip3 nuclear receptor interacting protein 3 0.081
Rxrg retinoid X receptor gamma 0.078
Calb1 calbindin 1 0.078
Car7 carbonic anhydrase 7 0.076
Kcnd3 potassium voltage-gated channel, Shal-related family, member 3 0.076
Dlx4 distal-less homeobox 4 0.076
Gad2 glutamic acid decarboxylase 2 0.076
Kifc2 kinesin family member C2 0.075
Adrb1 adrenergic receptor, beta 1 0.075
Camk2a calcium/calmodulin-dependent protein kinase II alpha 0.075
Cacna1a calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 0.074
Hrc histidine rich calcium binding protein 0.074
Wnk2 WNK lysine deficient protein kinase 2 0.073
Kcna2 potassium voltage-gated channel, shaker-related subfamily, member 2 0.071
Grid1 glutamate receptor, ionotropic, delta 1 0.069
Kcnip2 Kv channel-interacting protein 2 0.066
Grm8 glutamate receptor, metabotropic 8 0.065
Espn espin 0.065
Clcnka chloride channel Ka 0.064
Kcnj9 potassium inwardly-rectifying channel, subfamily J, member 9 0.064
Pou3f4 POU domain, class 3, transcription factor 4 0.063
B3gat1 beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) 0.063
Sim2 single-minded homolog 2 (Drosophila) 0.061
Grin2a glutamate receptor, ionotropic, NMDA2A (epsilon 1) 0.060
Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.059
Pou3f3 POU domain, class 3, transcription factor 3 0.058
Nrg3 neuregulin 3 0.058
Lmx1b LIM homeobox transcription factor 1 beta 0.058
Htr4 5 hydroxytryptamine (serotonin) receptor 4 0.057
Ptprb protein tyrosine phosphatase, receptor type, B 0.056
Chrm1 cholinergic receptor, muscarinic 1, CNS 0.055
Abcc8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 0.055
Kcnb1 potassium voltage gated channel, Shab-related subfamily, member 1 0.055
Slc26a4 solute carrier family 26, member 4 0.055
Mybpc3 myosin binding protein C, cardiac 0.054
Vipr1 vasoactive intestinal peptide receptor 1 0.054
Nptx2 neuronal pentraxin 2 0.054
Abcc9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 0.054
Rora RAR-related orphan receptor alpha 0.053
Pdzd3 PDZ domain containing 3 0.053
Dao D-amino acid oxidase 0.052
Npas1 neuronal PAS domain protein 1 0.050
Slc22a6 solute carrier family 22 (organic anion transporter), member 6 0.049
Cntn4 contactin 4 0.049
Naa11 N(alpha)-acetyltransferase 11, NatA catalytic subunit 0.049
Six3 sine oculis-related homeobox 3 homolog (Drosophila) 0.048
Mog myelin oligodendrocyte glycoprotein 0.048
Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 0.048
Zfp651 zinc finger protein 651 0.047
Sstr3 somatostatin receptor 3 0.045
Pdzk1 PDZ domain containing 1 0.045
Shc3 src homology 2 domain-containing transforming protein C3 0.045
Ush1g Usher syndrome 1G homolog (human) 0.045
Cux2 cut-like homeobox 2 0.044
Kcnd2 potassium voltage-gated channel, Shal-related family, member 2 0.043
Gabra2 gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2 0.043
Fgf12 fibroblast growth factor 12 0.041
Htr2c 5-hydroxytryptamine (serotonin) receptor 2C 0.041
Chrna4 cholinergic receptor, nicotinic, alpha polypeptide 4 0.041
Cacna2d2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 0.041
Slc27a1 solute carrier family 27 (fatty acid transporter), member 1 0.040
Mfsd4 major facilitator superfamily domain containing 4 0.040
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
CUL3 cullin 3 0.946
TBC1D10A TBC1 domain family, member 10A 0.883
KLHL3 kelch-like 3 (Drosophila) 0.840
WNK4 WNK lysine deficient protein kinase 4 0.612
EZR ezrin 0.576
TSC22D4 TSC22 domain family, member 4 0.430
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like 0.321
PAG1 phosphoprotein associated with glycosphingolipid microdomains 1 0.253
MED28 mediator complex subunit 28 0.242
CPSF6 cleavage and polyadenylation specific factor 6, 68kDa 0.229
NFE2L2 nuclear factor (erythroid-derived 2)-like 2 0.221
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.217
DAPK1 death-associated protein kinase 1 0.216
LNX1 ligand of numb-protein X 1 0.193
BTBD10 BTB (POZ) domain containing 10 0.130
DPP3 dipeptidyl-peptidase 3 0.123
ADRB2 adrenergic, beta-2-, receptor, surface 0.115
PTEN phosphatase and tensin homolog 0.108
OXSR1 oxidative-stress responsive 1 0.105
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 0.090
GOPC golgi-associated PDZ and coiled-coil motif containing 0.084
SLC9A3R2 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 0.066
PDZK1 PDZ domain containing 1 0.065
KBTBD7 kelch repeat and BTB (POZ) domain containing 7 0.064
NBR1 neighbor of BRCA1 gene 1 0.054
GLIS2 GLIS family zinc finger 2 0.054
PRMT6 protein arginine methyltransferase 6 0.050
SPOP speckle-type POZ protein 0.046
SNX20 sorting nexin 20 0.040
ZNF431 zinc finger protein 431 0.035
P2RY1 purinergic receptor P2Y, G-protein coupled, 1 0.034
BAG3 BCL2-associated athanogene 3 0.033
MAP1LC3A microtubule-associated protein 1 light chain 3 alpha 0.032
MAFG v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian) 0.031
ARAF v-raf murine sarcoma 3611 viral oncogene homolog 0.031
CLCN3 chloride channel 3 0.030
PRR13 proline rich 13 0.030
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 0.027
GABARAPL2 GABA(A) receptor-associated protein-like 2 0.025
WNK1 WNK lysine deficient protein kinase 1 0.024
DCUN1D1 DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae) 0.024
NF2 neurofibromin 2 (merlin) 0.022
VTA1 Vps20-associated 1 homolog (S. cerevisiae) 0.021
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 0.020
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.019
KLHL2 kelch-like 2, Mayven (Drosophila) 0.019
SETD7 SET domain containing (lysine methyltransferase) 7 0.018
DVL3 dishevelled, dsh homolog 3 (Drosophila) 0.018
ZMYND10 zinc finger, MYND-type containing 10 0.018
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2 0.017
ZBTB43 zinc finger and BTB domain containing 43 0.017
GET4 golgi to ER traffic protein 4 homolog (S. cerevisiae) 0.017
FAM46A family with sequence similarity 46, member A 0.017
UBA1 ubiquitin-like modifier activating enzyme 1 0.017
SESN2 sestrin 2 0.016
KIAA0174 KIAA0174 0.016
GABARAPL1 GABA(A) receptor-associated protein like 1 0.016
KLHDC5 kelch domain containing 5 0.016
ADAMTS10 ADAM metallopeptidase with thrombospondin type 1 motif, 10 0.015
PFN2 profilin 2 0.015
NUDCD3 NudC domain containing 3 0.014
DOCK7 dedicator of cytokinesis 7 0.014
PRKCI protein kinase C, iota 0.014
BMI1 BMI1 polycomb ring finger oncogene 0.014
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.014
SQSTM1 sequestosome 1 0.014
TUBB2B tubulin, beta 2B 0.013
FHOD3 formin homology 2 domain containing 3 0.013
HMGXB3 HMG box domain containing 3 0.012
C1orf94 chromosome 1 open reading frame 94 0.012
TULP3 tubby like protein 3 0.012
LYN v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.012
COIL coilin 0.012
KBTBD6 kelch repeat and BTB (POZ) domain containing 6 0.012
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1 0.012
TBC1D5 TBC1 domain family, member 5 0.012
ATXN2 ataxin 2 0.012
CDC37 cell division cycle 37 homolog (S. cerevisiae) 0.011
GSTCD glutathione S-transferase, C-terminal domain containing 0.011
OTX2 orthodenticle homeobox 2 0.011
WNK3 WNK lysine deficient protein kinase 3 0.011
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 0.011
KIAA2026 KIAA2026 0.011
DCUN1D5 DCN1, defective in cullin neddylation 1, domain containing 5 (S. cerevisiae) 0.011
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.011
OPRK1 opioid receptor, kappa 1 0.011
CPNE6 copine VI (neuronal) 0.011
KLHL20 kelch-like 20 (Drosophila) 0.011
KIAA1377 KIAA1377 0.010
GNB5 guanine nucleotide binding protein (G protein), beta 5 0.010
P2RY2 purinergic receptor P2Y, G-protein coupled, 2 0.010
ZHX2 zinc fingers and homeoboxes 2 0.010
ZNF580 zinc finger protein 580 0.010
RBM45 RNA binding motif protein 45 0.010
SGMS1 sphingomyelin synthase 1 0.010
MBIP MAP3K12 binding inhibitory protein 1 0.010
TUBA1A tubulin, alpha 1a 0.010
BCR breakpoint cluster region 0.010
SIRT6 sirtuin 6 0.010
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism