The network for 'polyamine biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

polyamine biosynthetic process

The chemical reactions and pathways resulting in the formation of polyamines, any organic compound containing two or more amino groups.

Name Description Probability Func Analog Organism
Eif5 eukaryotic translation initiation factor 5 0.113
Ctps cytidine 5'-triphosphate synthase 0.111
Lrrc59 leucine rich repeat containing 59 0.094
Ube2d3 ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) 0.090
Uck2 uridine-cytidine kinase 2 0.084
Kpna3 karyopherin (importin) alpha 3 0.082
Nop2 NOP2 nucleolar protein homolog (yeast) 0.082
Eif3j eukaryotic translation initiation factor 3, subunit J 0.080
Tfdp1 transcription factor Dp 1 0.073
Bzw1 basic leucine zipper and W2 domains 1 0.061
Ptp4a1 protein tyrosine phosphatase 4a1 0.058
Cul3 cullin 3 0.048
Kpna1 karyopherin (importin) alpha 1 0.044
Cacybp calcyclin binding protein 0.037
Nupl1 nucleoporin like 1 0.036
Tomm40 translocase of outer mitochondrial membrane 40 homolog (yeast) 0.036
Grwd1 glutamate-rich WD repeat containing 1 0.033
Etf1 eukaryotic translation termination factor 1 0.032
Nars asparaginyl-tRNA synthetase 0.031
Ipo5 importin 5 0.031
Mettl1 methyltransferase like 1 0.030
Bysl bystin-like 0.029
Rrp12 ribosomal RNA processing 12 homolog (S. cerevisiae) 0.028
Pa2g4 proliferation-associated 2G4 0.028
Abce1 ATP-binding cassette, sub-family E (OABP), member 1 0.026
Ran RAN, member RAS oncogene family 0.025
Strap serine/threonine kinase receptor associated protein 0.025
Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 0.024
Psme3 proteaseome (prosome, macropain) 28 subunit, 3 0.022
Ptges3 prostaglandin E synthase 3 (cytosolic) 0.021
Lin7c lin-7 homolog C (C. elegans) 0.020
Noc4l nucleolar complex associated 4 homolog (S. cerevisiae) 0.020
Mogs mannosyl-oligosaccharide glucosidase 0.020
Kpna2 karyopherin (importin) alpha 2 0.019
Nme1 non-metastatic cells 1, protein (NM23A) expressed in 0.019
Csda cold shock domain protein A 0.019
Ifrd1 interferon-related developmental regulator 1 0.018
Eif3b eukaryotic translation initiation factor 3, subunit B 0.017
Ddx39 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 0.016
Kti12 KTI12 homolog, chromatin associated (S. cerevisiae) 0.015
Pcbp1 poly(rC) binding protein 1 0.015
Hdgf hepatoma-derived growth factor 0.014
Eif2s3x eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked 0.014
Eif4e eukaryotic translation initiation factor 4E 0.014
Psat1 phosphoserine aminotransferase 1 0.014
Srsf2 serine/arginine-rich splicing factor 2 0.013
Ipo4 importin 4 0.013
Morf4l2 mortality factor 4 like 2 0.013
Mtpn myotrophin 0.013
Eif1a eukaryotic translation initiation factor 1A 0.013
Yrdc yrdC domain containing (E.coli) 0.012
Rangap1 RAN GTPase activating protein 1 0.012
Otud6b OTU domain containing 6B 0.012
Aars alanyl-tRNA synthetase 0.012
Galk1 galactokinase 1 0.012
Slc7a5 solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 0.011
Gmppb GDP-mannose pyrophosphorylase B 0.011
Creld2 cysteine-rich with EGF-like domains 2 0.011
Tra2b transformer 2 beta homolog (Drosophila) 0.011
Tcea1 transcription elongation factor A (SII) 1 0.011
Apex1 apurinic/apyrimidinic endonuclease 1 0.011
Kif2a kinesin family member 2A 0.011
Hccs holocytochrome c synthetase 0.011
Gspt1 G1 to S phase transition 1 0.011
Rbm19 RNA binding motif protein 19 0.011
Ccdc86 coiled-coil domain containing 86 0.010
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
DDX3X DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked 0.018
G3BP2 GTPase activating protein (SH3 domain) binding protein 2 0.013
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Lrrc59 leucine rich repeat containing 59 0.238
Ifrd1 interferon-related developmental regulator 1 0.114
Gorasp2 golgi reassembly stacking protein 2 0.114
Ptp4a1 protein tyrosine phosphatase type IVA, member 1 0.098
Hspa5 heat shock protein 5 0.063
Eif5a eukaryotic translation initiation factor 5A 0.057
Trmt61a tRNA methyltransferase 61 homolog A (S. cerevisiae) 0.045
Odc1 ornithine decarboxylase 1 0.038
Nus1 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) 0.032
Hiat1 hippocampus abundant gene transcript 1 0.028
Rbm18 RNA binding motif protein 18 0.028
Arf4 ADP-ribosylation factor 4 0.027
Rybp RING1 and YY1 binding protein 0.023
Chordc1 cysteine and histidine-rich domain (CHORD)-containing 1 0.020
Coq10b coenzyme Q10 homolog B (S. cerevisiae) 0.020
Dnaja1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.018
Hook1 hook homolog 1 (Drosophila) 0.017
Aimp2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 0.017
Trim27 tripartite motif-containing 27 0.017
Rab6a RAB6A, member RAS oncogene family 0.017
Eif4e eukaryotic translation initiation factor 4E 0.016
Rraga Ras-related GTP binding A 0.016
Hnrnpab heterogeneous nuclear ribonucleoprotein A/B 0.016
Eef1e1 eukaryotic translation elongation factor 1 epsilon 1 0.016
Manf mesencephalic astrocyte-derived neurotrophic factor 0.016
Dnaja2 DnaJ (Hsp40) homolog, subfamily A, member 2 0.016
Ipo4 importin 4 0.015
Nop16 NOP16 nucleolar protein homolog (yeast) 0.015
Taf10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor 0.014
Scamp4 secretory carrier membrane protein 4 0.013
Hsph1 heat shock 105/110 protein 1 0.013
Eif3b eukaryotic translation initiation factor 3, subunit B 0.013
Tsg101 tumor susceptibility gene 101 0.012
Etf1 eukaryotic translation termination factor 1 0.011
Uso1 USO1 homolog, vesicle docking protein (yeast) 0.011
Amigo3 adhesion molecule with Ig like domain 3 0.011
Ddx3x DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked 0.010
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
UBI4 Ubi4p 0.021