The network for 'organism emergence from protective structure' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

organism emergence from protective structure

The developmental process in which an organism emerges from a surrounding protective structure such as an egg or pupa case.

Name Description Probability Func Analog Organism
epb41 erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked) 0.278
pcsk1 proprotein convertase subtilisin/kexin type 1 0.243
ywhabb tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b 0.228
ihha Indian hedgehog homolog a 0.224
si:ch211-59d15.5 si:ch211-59d15.5 0.207
ywhabl tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like 0.197
ywhae1 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1 0.196
ywhai tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, iota polypeptide 0.176
alas2 aminolevulinate, delta-, synthetase 2 0.149
csnk1a1 casein kinase 1, alpha 1 0.141
gapdhs glyceraldehyde-3-phosphate dehydrogenase, spermatogenic 0.139
bub3 BUB3 budding uninhibited by benzimidazoles 3 homolog (yeast) 0.126
si:ch211-51m24.3 si:ch211-51m24.3 0.118
fras1 Fraser syndrome 1 0.107
hnrnpa0l heterogeneous nuclear ribonucleoprotein A0, like 0.106
cyp3a65 cytochrome P450, family 3, subfamily A, polypeptide 65 0.106
lsm7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.103
mitfa microphthalmia-associated transcription factor a 0.102
cltcb clathrin, heavy polypeptide b (Hc) 0.096
atp6v0ca ATPase, H+ transporting, lysosomal, V0 subunit c, a 0.088
robo1 roundabout homolog 1 0.088
tagln2 transgelin 2 0.088
smek2 SMEK homolog 2, suppressor of mek1 (Dictyostelium) 0.087
dbh dopamine beta hydroxylase 0.084
pkm2a pyruvate kinase, muscle, a 0.084
mus81 MUS81 endonuclease homolog (yeast) 0.083
ltk leukocyte tyrosine kinase 0.083
pdlim1 PDZ and LIM domain 1 (elfin) 0.083
hk1 hexokinase 1 0.083
cel.1 carboxyl ester lipase, tandem duplicate 1 0.080
sf3b14 splicing factor 3B 0.078
edar ectodysplasin A receptor 0.078
cpb1 carboxypeptidase B1 (tissue) 0.077
sf3a2 splicing factor 3a, subunit 2 0.077
furinb furin (paired basic amino acid cleaving enzyme) b 0.076
plcb3 phospholipase C, beta 3 (phosphatidylinositol-specific) 0.076
uchl1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.075
ap2b1 adaptor-related protein complex 2, beta 1 subunit 0.073
smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.073
caprin1a cell cycle associated protein 1a 0.072
sf3b4 splicing factor 3b, subunit 4 0.071
chd chordin 0.069
disp1 dispatched homolog 1 (Drosophila) 0.067
cacna1da calcium channel, voltage-dependent, L type, alpha 1D subunit, a 0.067
szl sizzled 0.066
vps35 vacuolar protein sorting 35 (yeast) 0.066
nadka NAD kinase a 0.066
ctsl1b cathepsin L, 1 b 0.065
pcsk7 proprotein convertase subtilisin/kexin type 7 0.065
srd5a2a steroid-5-alpha-reductase, alpha polypeptide 2a 0.064
pom121 POM121 membrane glycoprotein (rat) 0.064
psmd1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 0.064
paf1 paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) 0.062
chaf1b chromatin assembly factor 1, subunit B 0.062
tuba8l3 tubulin, alpha 8 like 3 0.061
krt4 keratin 4 0.061
smarca5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 0.061
prpf39 PRP39 pre-mRNA processing factor 39 homolog (yeast) 0.060
zgc:110325 zgc:110325 0.060
zgc:100817 zgc:100817 0.059
sptb spectrin, beta, erythrocytic 0.059
jun jun proto-oncogene 0.059
angptl3 angiopoietin-like 3 0.059
eny2 enhancer of yellow 2 homolog (Drosophila) 0.056
chek1 CHK1 checkpoint homolog (S. pombe) 0.056
u2af2b U2 small nuclear RNA auxiliary factor 2b 0.056
fbn2b fibrillin 2b 0.055
gadd45ba growth arrest and DNA-damage-inducible, beta a 0.054
rtn1a reticulon 1a 0.054
si:ch211-278b8.3 si:ch211-278b8.3 0.053
polr2b polymerase (RNA) II (DNA directed) polypeptide B 0.052
ctgf connective tissue growth factor 0.052
kbp kif1-binding protein 0.051
hsp47 heat shock protein 47 0.050
frem2a Fras1 related extracellular matrix protein 2a 0.050
psmc5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 0.049
perp PERP, TP53 apoptosis effector 0.049
sap30bp SAP30 binding protein and SAP30 binding protein 0.048
edn1 endothelin 1 0.047
sept7a septin 7a 0.047
krt8 keratin 8 0.047
ccm2 cerebral cavernous malformation 2 0.046
nnt nicotinamide nucleotide transhydrogenase 0.046
arpp19b cAMP-regulated phosphoprotein 19b 0.046
hpca hippocalcin 0.045
shbg sex hormone binding globulin 0.045
papss2b 3'-phosphoadenosine 5'-phosphosulfate synthase 2b 0.044
zgc:112359 zgc:112359 0.044
ash2l ash2 (absent, small, or homeotic)-like (Drosophila) 0.044
als2b amyotrophic lateral sclerosis 2b (juvenile) 0.044
sc:d812 sc:d812 0.044
si:dkey-72l14.8 si:dkey-72l14.8 0.043
zgc:77304 zgc:77304 0.043
abcb3l1 ATP-binding cassette, sub-family B (MDR/TAP), member 3 like 1 0.043
ywhaqb tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b 0.043
cacnb1 calcium channel, voltage-dependent, beta 1 subunit 0.043
ubtd2 ubiquitin domain containing 2 0.043
prkca protein kinase C, alpha 0.042
fip1l1 FIP1 like 1 (S. cerevisiae) 0.042
frem1a Fras1 related extracellular matrix 1a 0.042
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
puf-7 Protein PUF-7 0.229
ace-1 Protein ACE-1 0.198
puf-6 Protein PUF-6 0.111
lin-12 Protein LIN-12 0.103
oma-1 Protein OMA-1 0.096
unc-54 Protein UNC-54 0.082
pph-4.1 Protein PPH-4.1 0.071
ace-3 Protein ACE-3 0.067
lec-8 Protein LEC-8 0.062
ace-2 Protein ACE-2 0.054
pry-1 Protein PRY-1 0.054
mex-5 Protein MEX-5 0.052
rad-51 Protein RAD-51 0.047
unc-60 Protein UNC-60 0.047
pal-1 Protein PAL-1 0.046
ima-1 Protein IMA-1 0.041
ppfr-4 Protein PPFR-4 0.041
arp-1 Protein ARP-1 0.040
C35D10.7 Protein C35D10.7 0.039
T28D9.3 Protein T28D9.3 0.036
W03F8.4 Protein W03F8.4 0.035
pph-6 Protein PPH-6 0.034
mlh-1 Protein MLH-1 0.034
B0464.6 Protein B0464.6 0.034
sos-1 Protein SOS-1 0.034
nos-2 Protein NOS-2 0.034
sur-6 Protein SUR-6 0.033
pqn-44 Protein PQN-44 0.033
T11G6.8 Protein T11G6.8 0.033
lmp-1 Protein LMP-1 0.032
lag-2 Protein LAG-2 0.032
paqr-1 Protein PAQR-1 0.031
vab-3 Protein VAB-3 0.031
C30F12.4 Protein C30F12.4 0.031
ztf-4 Protein ZTF-4 0.031
C02F5.6 Protein C02F5.6 0.030
gip-1 Protein GIP-1 0.030
spd-2 Protein SPD-2 0.029
pop-1 Protein POP-1 0.028
C33H5.18 Protein C33H5.18 0.028
orc-2 Protein ORC-2 0.028
lag-1 Protein LAG-1 0.028
fat-2 Protein FAT-2 0.028
dnc-3 Protein DNC-3 0.027
wago-4 Protein WAGO-4 0.027
lrr-1 Protein LRR-1 0.027
ect-2 Protein ECT-2 0.027
K08E3.4 Protein K08E3.4 0.027
tag-333 Protein TAG-333 0.026
CELE_C08F11.13 Protein C08F11.13 0.026
ssl-1 Protein SSL-1 0.026
T12E12.3 Protein T12E12.3 0.026
teg-4 Protein TEG-4 0.026
snr-6 Protein SNR-6 0.026
gck-1 Protein GCK-1 0.026
let-92 Protein LET-92 0.026
ensa-1 Protein ENSA-1 0.026
C35A5.8 Protein C35A5.8 0.025
mom-2 Protein MOM-2 0.025
dnj-5 Protein DNJ-5 0.025
sel-10 Protein SEL-10 0.024
snrp-200 Protein SNRP-200 0.023
imp-3 Protein IMP-3 0.023
skpt-1 Protein SKPT-1 0.023
T27A3.7 Protein T27A3.7 0.023
trt-1 Protein TRT-1 0.023
C48B4.6 Protein C48B4.6 0.023
T24H7.3 Protein T24H7.3 0.023
tag-349 Protein TAG-349 0.023
F56C9.3 Protein F56C9.3 0.023
hpo-35 Protein HPO-35 0.022
CELE_W02F12.3 Protein W02F12.3 0.022
C26F1.3 Protein C26F1.3 0.022
C03C10.5 Protein C03C10.5 0.022
pie-1 Protein PIE-1 0.022
CELE_C32F10.4 Protein C32F10.4 0.021
mel-26 Protein MEL-26 0.021
CELE_C27D9.1 Protein C27D9.1 0.021
ptr-8 Protein PTR-8 0.021
K10D2.5 Protein K10D2.5 0.021
CELE_ZC239.4 Protein ZC239.4 0.021
C31H1.8 Protein C31H1.8 0.021
cyb-2.1 Protein CYB-2.1 0.021
let-60 Protein LET-60 0.021
rars-1 Protein RARS-1 0.021
C27A12.7 Protein C27A12.7 0.020
dmd-6 Protein DMD-6 0.020
efa-6 Protein EFA-6 0.020
zif-1 Protein ZIF-1 0.020
T21C9.4 Protein T21C9.4 0.020
D1081.7 Protein D1081.7 0.020
ZK973.9 Protein ZK973.9 0.020
clec-196 Protein CLEC-196 0.020
drh-1 Protein DRH-1 0.020
cct-7 Protein CCT-7 0.019
pas-1 Protein PAS-1 0.019
glp-1 Protein GLP-1 0.019
T22C1.4 Protein T22C1.4 0.019
Y55F3BR.1 Protein Y55F3BR.1 0.019
mex-6 Protein MEX-6 0.019
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.958
Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.957
Ddx60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 0.721
Smarcc1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 0.631
Lrrk2 leucine-rich repeat kinase 2 0.518
Ppp2ca protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform 0.479
Nanog Nanog homeobox 0.476
Arid1b AT rich interactive domain 1B (SWI-like) 0.369
Arid1a AT rich interactive domain 1A (SWI-like) 0.309
Smarca2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 0.284
Smarcb1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 0.251
Rpgrip1l Rpgrip1-like 0.241
Trim25 tripartite motif-containing 25 0.219
Ctnnb1 catenin (cadherin associated protein), beta 1 0.212
Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.186
Smarcd1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 0.180
Crk v-crk sarcoma virus CT10 oncogene homolog (avian) 0.149
Ppp2r1a protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform 0.147
Trp53 transformation related protein 53 0.119
Dnmt1 DNA methyltransferase (cytosine-5) 1 0.115
Mcm5 minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae) 0.111
Smarcc2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 0.109
Vhl von Hippel-Lindau tumor suppressor 0.103
Tceb3 transcription elongation factor B (SIII), polypeptide 3 0.096
Gbp7 guanylate binding protein 7 0.083
Timeless timeless homolog (Drosophila) 0.081
Brca2 breast cancer 2 0.078
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.076
Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.075
Th1l TH1-like homolog (Drosophila) 0.071
1500010J02Rik RIKEN cDNA 1500010J02 gene 0.068
Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.064
Eno1 enolase 1, alpha non-neuron 0.061
Lrp6 low density lipoprotein receptor-related protein 6 0.055
Plcg1 phospholipase C, gamma 1 0.051
Pgd phosphogluconate dehydrogenase 0.050
Axin1 axin 1 0.050
Sf3a2 splicing factor 3a, subunit 2 0.046
Brd4 bromodomain containing 4 0.044
Ikzf1 IKAROS family zinc finger 1 0.043
Ncam1 neural cell adhesion molecule 1 0.043
Taf6 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor 0.042
Ints3 integrator complex subunit 3 0.042
Mlh1 mutL homolog 1 (E. coli) 0.041
Brca1 breast cancer 1 0.041
Apc adenomatosis polyposis coli 0.040
Smarce1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 0.040
Pthlh parathyroid hormone-like peptide 0.040
Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase 0.040
Wdr19 WD repeat domain 19 0.039
Serp1 stress-associated endoplasmic reticulum protein 1 0.039
Armcx2 armadillo repeat containing, X-linked 2 0.038
Creb1 cAMP responsive element binding protein 1 0.038
Yap1 yes-associated protein 1 0.037
Mgat2 mannoside acetylglucosaminyltransferase 2 0.037
Cadps2 Ca2+-dependent activator protein for secretion 2 0.037
Adss adenylosuccinate synthetase, non muscle 0.036
Epn1 epsin 1 0.035
Smarcd3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 0.034
Pgrmc1 progesterone receptor membrane component 1 0.034
Irf6 interferon regulatory factor 6 0.034
Cfl1 cofilin 1, non-muscle 0.034
Trp63 transformation related protein 63 0.033
Dnajb9 DnaJ (Hsp40) homolog, subfamily B, member 9 0.033
Ssbp2 single-stranded DNA binding protein 2 0.033
Twist2 twist homolog 2 (Drosophila) 0.032
Foxo1 forkhead box O1 0.032
Acly ATP citrate lyase 0.032
Irgm1 immunity-related GTPase family M member 1 0.032
Mnd1 meiotic nuclear divisions 1 homolog (S. cerevisiae) 0.031
Lamp1 lysosomal-associated membrane protein 1 0.031
Lig1 ligase I, DNA, ATP-dependent 0.031
H2afx H2A histone family, member X 0.031
Rtp4 receptor transporter protein 4 0.031
Ifi44 interferon-induced protein 44 0.031
Ncapd2 non-SMC condensin I complex, subunit D2 0.031
Rps6kb1 ribosomal protein S6 kinase, polypeptide 1 0.030
Ints9 integrator complex subunit 9 0.030
Hspa5 heat shock protein 5 0.030
Prmt5 protein arginine N-methyltransferase 5 0.030
Esrrb estrogen related receptor, beta 0.029
Smpd3 sphingomyelin phosphodiesterase 3, neutral 0.029
Psmd11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 0.029
Rnf135 ring finger protein 135 0.029
Ppp1ca protein phosphatase 1, catalytic subunit, alpha isoform 0.029
Bmp2 bone morphogenetic protein 2 0.029
Has2 hyaluronan synthase 2 0.029
Ifit1 interferon-induced protein with tetratricopeptide repeats 1 0.029
Tuba1a tubulin, alpha 1A 0.028
Pgam1 phosphoglycerate mutase 1 0.028
H47 histocompatibility 47 0.028
Tdp1 tyrosyl-DNA phosphodiesterase 1 0.027
Tbx15 T-box 15 0.027
Gtf2h4 general transcription factor II H, polypeptide 4 0.026
Ndn necdin 0.026
U2af2 U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2 0.026
Ddx58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.026
Rev3l REV3-like, catalytic subunit of DNA polymerase zeta RAD54 like (S. cerevisiae) 0.026
Serpinb5 serine (or cysteine) peptidase inhibitor, clade B, member 5 0.026
Rpl7l1 ribosomal protein L7-like 1 0.026
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism