The network for 'regulation of neurological system process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of neurological system process

Any process that modulates the frequency, rate or extent of a neurophysiological process, an organ system process carried out by any of the organs or tissues of neurological system.

Danio rerio
Name Description Probability Func Analog Organism
wnt1 wingless-type MMTV integration site family, member 1 0.556
ncam2 neural cell adhesion molecule 2 0.543
eif2c4 eukaryotic translation initiation factor 2C, 4 0.428
oprd1a opioid receptor, delta 1a 0.372
si:ch211-209p5.2 si:ch211-209p5.2 0.303
tac1 tachykinin 1 0.289
oprd1b opioid receptor, delta 1b 0.288
ptpra protein tyrosine phosphatase, receptor type, A 0.282
oprm1 opioid receptor, mu 1 0.281
sema3aa semaphorin 3aa 0.254
ednrb1 endothelin receptor B 0.243
hgfb hepatocyte growth factor b 0.232
ppp2r5d protein phosphatase 2, regulatory subunit B', delta 0.229
cfl2l cofilin 2, like 0.224
kita kit receptor a 0.199
mc4r melanocortin 4 receptor 0.185
oxtl oxytocin-like 0.183
nog2 noggin 2 0.177
bhlhe41 basic helix-loop-helix family, member e41 0.170
esr1 estrogen receptor 1 0.168
gnrh3 gonadotropin-releasing hormone 3 0.154
lhx2b LIM homeobox 2b 0.143
ptch2 patched 2 0.141
vax2 ventral anterior homeobox 2 0.128
hbbe1.1 hemoglobin beta embryonic-1.1 0.121
prom1b prominin 1 b 0.117
six3b sine oculis homeobox homolog 3b 0.117
sb:eu275 sb:eu275 0.116
pcdh18b protocadherin 18b 0.116
mchr1a melanin-concentrating hormone receptor 1a 0.113
crh corticotropin releasing hormone 0.110
esr2b estrogen receptor 2b 0.104
csrnp1b cysteine-serine-rich nuclear protein 1b 0.094
meis2.2 myeloid ecotropic viral integration site 2.2 0.089
uts1 urotensin 1 0.086
ddc dopa decarboxylase 0.085
rock2b rho-associated, coiled-coil containing protein kinase 2b 0.084
crabp1a cellular retinoic acid binding protein 1a 0.084
mapk3 mitogen-activated protein kinase 3 0.082
dbh dopamine beta hydroxylase 0.079
LOC100536464 protein FAM126B-like 0.079
nadl1.1 neural adhesion molecule L1.1 0.076
rtf1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 0.076
slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.076
gpatch8 G patch domain containing 8 0.076
zmynd11 zinc finger, MYND domain containing 11 0.074
gfra1a gdnf family receptor alpha 1a 0.074
efr3a EFR3 homolog A (S. cerevisiae) 0.071
slc6a6 solute carrier family 6 (neurotransmitter transporter, taurine), member 6 0.071
zgc:101761 zgc:101761 0.070
LOC100332193 growth hormone secretagogue receptor type 1-like 0.068
htr1aa 5-hydroxytryptamine (serotonin) receptor 1A a 0.066
dlg1 discs, large (Drosophila) homolog 1 0.065
ptp4a1 protein tyrosine phosphatase type IVA, member 1 0.063
LOC100006361 galanin-like 0.063
fgfr1b fibroblast growth factor receptor 1b 0.061
gli1 GLI-Kruppel family member 1 0.060
oprl1 opiate receptor-like 1 0.059
arid4a AT rich interactive domain 4A (RBP1-like) 0.058
slc30a7 solute carrier family 30 (zinc transporter), member 7 0.058
ep300b E1A binding protein p300 b 0.055
efna5b ephrin A5b 0.055
calcr calcitonin receptor 0.053
otpa orthopedia homolog a 0.052
pax7b paired box gene 7b 0.052
alp alkaline phosphatase 0.052
lamb2 laminin, beta 2 (laminin S) 0.051
zgc:113312 zgc:113312 0.051
vdra vitamin D receptor a 0.049
mapk1 mitogen-activated protein kinase 1 0.048
ap1g1 adaptor-related protein complex 1, gamma 1 subunit 0.048
ash1l ash1 (absent, small, or homeotic)-like (Drosophila) 0.048
gad2 glutamate decarboxylase 2 0.048
drd2a dopamine receptor D2a 0.047
phox2a paired-like homeobox 2a 0.047
med12 mediator of RNA polymerase II transcription, subunit 12 homolog 0.047
tcf7l2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.046
rpz rapunzel 0.046
gsk3a glycogen synthase kinase 3 alpha 0.045
hcrtr2 hypocretin (orexin) receptor 2 0.045
b4galt6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 0.045
dcst1 DC-STAMP domain containing 1 0.044
ptena phosphatase and tensin homolog A 0.044
LOC100535549 cytoplasmic polyadenylation element-binding protein 4-like 0.044
brd4 bromodomain containing 4 0.043
pax3a paired box gene 3a 0.043
avpl arginine vasopressin-like 0.043
snx27 sorting nexin family member 27 0.043
pdlim3b PDZ and LIM domain 3b 0.043
oc90 otoconin 90 0.042
dpysl5b dihydropyrimidinase-like 5b 0.042
grin1a glutamate receptor, ionotropic, N-methyl D-aspartate 1a 0.042
pcp4a Purkinje cell protein 4a 0.042
ihhb Indian hedgehog homolog b 0.042
mapk14a mitogen-activated protein kinase 14a 0.042
ahcyl2 S-adenosylhomocysteine hydrolase-like 2 0.041
dlg2 discs, large (Drosophila) homolog 2 0.041
dab1a disabled homolog 1a (Drosophila) 0.041
ptpn11a protein tyrosine phosphatase, non-receptor type 11, a 0.041
ntn2 netrin 2 0.040
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
jeb jelly belly 0.077
Nmdar1 NMDA receptor 1 0.037
caz cabeza 0.028
tipE temperature-induced paralytic E 0.026
oa2 octopamine receptor 2 0.025
CG13253 CG13253 gene product from transcript CG13253-RB 0.025
CrebB-17A Cyclic-AMP response element binding protein B at 17A 0.024
rl rolled 0.021
Dsk Drosulfakinin 0.017
bnl branchless 0.016
egr eiger 0.015
MESK2 Misexpression suppressor of KSR 2 0.015
Nf1 Neurofibromin 1 0.014
nAcRbeta-96A nicotinic Acetylcholine Receptor beta 96A 0.013
Fps85D Fps oncogene analog 0.012
sda slamdance 0.011
CG34139 CG34139 gene product from transcript CG34139-RD 0.011
Ten-a Tenascin accessory 0.011
Fas2 Fasciclin 2 0.010
Gadd45 CG11086 gene product from transcript CG11086-RA 0.010
shi shibire 0.010
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
EIF2C2 eukaryotic translation initiation factor 2C, 2 0.729
EIF2C1 eukaryotic translation initiation factor 2C, 1 0.353
TRAF2 TNF receptor-associated factor 2 0.340
CCR5 chemokine (C-C motif) receptor 5 0.298
TRAF1 TNF receptor-associated factor 1 0.259
DICER1 dicer 1, ribonuclease type III 0.194
CAV1 caveolin 1, caveolae protein, 22kDa 0.184
HBB hemoglobin, beta 0.167
TNRC6A trinucleotide repeat containing 6A 0.147
HBG2 hemoglobin, gamma G 0.129
CCL4 chemokine (C-C motif) ligand 4 0.104
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.088
MPDZ multiple PDZ domain protein 0.086
DLG4 discs, large homolog 4 (Drosophila) 0.079
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 0.070
TNF tumor necrosis factor 0.066
EIF2C3 eukaryotic translation initiation factor 2C, 3 0.065
TRAF5 TNF receptor-associated factor 5 0.064
TRADD TNFRSF1A-associated via death domain 0.063
IL10RA interleukin 10 receptor, alpha 0.057
CCL2 chemokine (C-C motif) ligand 2 0.055
KCNA1 potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) 0.049
CXCL9 chemokine (C-X-C motif) ligand 9 0.044
TNRC6C trinucleotide repeat containing 6C 0.036
VAC14 Vac14 homolog (S. cerevisiae) 0.033
TRAF3 TNF receptor-associated factor 3 0.033
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 0.031
STMN2 stathmin-like 2 0.030
CCL22 chemokine (C-C motif) ligand 22 0.030
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.027
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.023
CD40 CD40 molecule, TNF receptor superfamily member 5 0.022
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 0.021
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator 0.021
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 0.020
CCL11 chemokine (C-C motif) ligand 11 0.019
MET met proto-oncogene (hepatocyte growth factor receptor) 0.018
CCR7 chemokine (C-C motif) receptor 7 0.017
NEDD4 neural precursor cell expressed, developmentally down-regulated 4 0.017
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 0.017
TNRC6B trinucleotide repeat containing 6B 0.017
CCL19 chemokine (C-C motif) ligand 19 0.017
CXCL11 chemokine (C-X-C motif) ligand 11 0.017
CCL7 chemokine (C-C motif) ligand 7 0.016
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 0.016
TICAM2 toll-like receptor adaptor molecule 2 0.016
CCR1 chemokine (C-C motif) receptor 1 0.014
SLC9A3R1 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 0.014
F11R F11 receptor 0.013
DPP4 dipeptidyl-peptidase 4 0.013
VCAM1 vascular cell adhesion molecule 1 0.013
CCL8 chemokine (C-C motif) ligand 8 0.013
IFNG interferon, gamma 0.012
DLGAP1 discs, large (Drosophila) homolog-associated protein 1 0.012
IL10 interleukin 10 0.011
CCR4 chemokine (C-C motif) receptor 4 0.011
ARRDC3 arrestin domain containing 3 0.011
CAV2 caveolin 2 0.010
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.989
Drd2 dopamine receptor D2 0.407
Htr1a 5-hydroxytryptamine (serotonin) receptor 1A 0.276
Oprm1 opioid receptor, mu 1 0.271
Klk1b11 kallikrein 1-related peptidase b11 0.218
Ddx60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 0.191
Klk1b5 kallikrein 1-related peptidase b5 0.185
Klk1b21 kallikrein 1-related peptidase b21 0.184
Klk1b1 kallikrein 1-related peptidase b1 0.180
Klk1b26 kallikrein 1-related petidase b26 0.154
Eif2c2 eukaryotic translation initiation factor 2C, 2 0.122
Klk1b8 kallikrein 1-related peptidase b8 0.121
Cacna2d2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 0.118
Htr4 5 hydroxytryptamine (serotonin) receptor 4 0.114
Hbb-b1 hemoglobin, beta adult major chain 0.099
Ryr2 ryanodine receptor 2, cardiac 0.091
Sh3gl2 SH3-domain GRB2-like 2 0.090
Klk1 kallikrein 1 0.081
Pparg peroxisome proliferator activated receptor gamma 0.081
Pnpla2 patatin-like phospholipase domain containing 2 0.076
Grm1 glutamate receptor, metabotropic 1 0.075
Cckbr cholecystokinin B receptor 0.072
Ddx6 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 0.071
Ctnnb1 catenin (cadherin associated protein), beta 1 0.069
Emx1 empty spiracles homolog 1 (Drosophila) 0.068
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.063
Egr3 early growth response 3 0.062
Crhr1 corticotropin releasing hormone receptor 1 0.062
Ptgs2 prostaglandin-endoperoxide synthase 2 0.061
Tlr2 toll-like receptor 2 0.059
Ccl2 chemokine (C-C motif) ligand 2 0.058
Klk1b9 kallikrein 1-related peptidase b9 0.058
Nos2 nitric oxide synthase 2, inducible 0.056
ND6 NADH dehydrogenase subunit 6 0.055
Klk6 kallikrein related-peptidase 6 0.055
Bdkrb2 bradykinin receptor, beta 2 0.054
Sstr4 somatostatin receptor 4 0.053
Klk1b16 kallikrein 1-related peptidase b16 0.053
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.053
Nedd4l neural precursor cell expressed, developmentally down-regulated gene 4-like 0.052
Camk2a calcium/calmodulin-dependent protein kinase II alpha 0.052
Grin2a glutamate receptor, ionotropic, NMDA2A (epsilon 1) 0.051
Trpc4 transient receptor potential cation channel, subfamily C, member 4 0.049
Adra2c adrenergic receptor, alpha 2c 0.048
Grid1 glutamate receptor, ionotropic, delta 1 0.048
Dlg2 discs, large homolog 2 (Drosophila) 0.043
Il6 interleukin 6 0.042
Gad2 glutamic acid decarboxylase 2 0.041
Kl klotho 0.040
Gpr12 G-protein coupled receptor 12 0.040
Fmr1 fragile X mental retardation syndrome 1 homolog 0.040
Expi extracellular proteinase inhibitor 0.039
Slc12a5 solute carrier family 12, member 5 0.039
Chrm1 cholinergic receptor, muscarinic 1, CNS 0.039
Ctrb1 chymotrypsinogen B1 0.039
Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 0.038
Bsn bassoon 0.038
Csmd1 CUB and Sushi multiple domains 1 0.037
Ret ret proto-oncogene 0.036
Trhr thyrotropin releasing hormone receptor 0.036
Prkcz protein kinase C, zeta 0.036
Cntn3 contactin 3 0.036
Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 0.036
Il10 interleukin 10 0.036
Cacna1b calcium channel, voltage-dependent, N type, alpha 1B subunit 0.035
Gria1 glutamate receptor, ionotropic, AMPA1 (alpha 1) 0.035
Nrg3 neuregulin 3 0.035
5430421N21Rik RIKEN cDNA 5430421N21 gene 0.035
Sstr1 somatostatin receptor 1 0.034
Kcnq2 potassium voltage-gated channel, subfamily Q, member 2 0.034
Ntsr2 neurotensin receptor 2 0.033
Trim32 tripartite motif-containing 32 0.033
Pcdh12 protocadherin 12 0.033
Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b 0.033
Prkcc protein kinase C, gamma 0.032
Ptk2 PTK2 protein tyrosine kinase 2 0.032
Trh thyrotropin releasing hormone 0.032
Mas1 MAS1 oncogene 0.031
Tac2 tachykinin 2 0.031
Klk1b27 kallikrein 1-related peptidase b27 0.031
Klk1b24 kallikrein 1-related peptidase b24 0.031
Oprk1 opioid receptor, kappa 1 0.031
Cplx1 complexin 1 0.031
Lyst lysosomal trafficking regulator 0.030
Cd44 CD44 antigen 0.030
Ptprn2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.030
Dlgap1 discs, large (Drosophila) homolog-associated protein 1 0.030
Lin7b lin-7 homolog B (C. elegans) 0.029
Gng4 guanine nucleotide binding protein (G protein), gamma 4 0.029
Hrk harakiri, BCL2 interacting protein (contains only BH3 domain) 0.029
Sstr3 somatostatin receptor 3 0.028
Akap9 A kinase (PRKA) anchor protein (yotiao) 9 0.028
Nfatc2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 0.028
Adrb1 adrenergic receptor, beta 1 0.027
Ren1 renin 1 structural 0.027
Gabrg3 gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3 0.027
Kcnh1 potassium voltage-gated channel, subfamily H (eag-related), member 1 0.027
Grpr gastrin releasing peptide receptor 0.027
Gpr83 G protein-coupled receptor 83 0.027
Vip vasoactive intestinal polypeptide 0.026
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Galr1 galanin receptor 1 0.427
Hr hairless 0.337
Cyp2g1 cytochrome P450, family 2, subfamily g, polypeptide 1 0.249
Adora2a adenosine A2a receptor 0.247
Mag myelin-associated glycoprotein 0.163
Ccl4 chemokine (C-C motif) ligand 4 0.149
Oprk1 opioid receptor, kappa 1 0.148
Cxcl10 chemokine (C-X-C motif) ligand 10 0.147
Kcna3 potassium voltage-gated channel, shaker-related subfamily, member 3 0.136
Aqp8 aquaporin 8 0.135
Mchr1 melanin-concentrating hormone receptor 1 0.131
Il1rn interleukin 1 receptor antagonist 0.130
Gzmk granzyme K 0.125
Htr7 5-hydroxytryptamine (serotonin) receptor 7 0.119
Cyp21a1 cytochrome P450, family 21, subfamily a, polypeptide 1 0.116
Pcdhb12 protocadherin beta 12 0.115
Kcnj16 potassium inwardly-rectifying channel, subfamily J, member 16 0.115
Ctsj cathepsin J 0.114
Agtr1a angiotensin II receptor, type 1a 0.109
Gucy2f guanylate cyclase 2F 0.109
Phkg1 phosphorylase kinase, gamma 1 0.106
Htr2c 5-hydroxytryptamine (serotonin) receptor 2C 0.102
Fosl1 fos-like antigen 1 0.100
Ntrk1 neurotrophic tyrosine kinase, receptor, type 1 0.098
Scn10a sodium channel, voltage-gated, type X, alpha subunit 0.097
A3galt2 alpha 1,3-galactosyltransferase 2 0.096
Scnn1g sodium channel, nonvoltage-gated 1, gamma 0.093
Adam7 ADAM metallopeptidase domain 7 0.091
Gpr83 G protein-coupled receptor 83 0.089
Ednrb endothelin receptor type B 0.088
P2ry6 pyrimidinergic receptor P2Y, G-protein coupled, 6 0.088
Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 0.086
Grin2a glutamate receptor, ionotropic, N-methyl D-aspartate 2A 0.086
Tchh trichohyalin 0.085
Cxcl6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) 0.083
Gabrg1 gamma-aminobutyric acid (GABA) A receptor, gamma 1 0.082
Csf1 colony stimulating factor 1 (macrophage) 0.080
Mamdc4 MAM domain containing 4 0.079
Olr226 olfactory receptor 226 0.078
Kcnc2 potassium voltage gated channel, Shaw-related subfamily, member 2 0.077
Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 0.076
Adra2c adrenergic, alpha-2C-, receptor 0.073
Prl2a1 Prolactin family 2, subfamily a, member 1 0.073
Met met proto-oncogene 0.072
St8sia4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 0.071
Pnliprp2 pancreatic lipase-related protein 2 0.070
Gip gastric inhibitory polypeptide 0.070
Fat3 FAT tumor suppressor homolog 3 (Drosophila) 0.069
Itpkb inositol 1,4,5-trisphosphate 3-kinase B 0.069
Orm1 orosomucoid 1 0.069
Cxcl2 chemokine (C-X-C motif) ligand 2 0.069
Hbb-b1 hemoglobin, beta adult major chain 0.068
Pemt phosphatidylethanolamine N-methyltransferase 0.068
Hrh3 histamine receptor H3 0.068
Itgam integrin, alpha M 0.067
Crhbp corticotropin releasing hormone binding protein 0.066
Folh1 folate hydrolase 1 0.066
Prl prolactin 0.065
Fgf14 fibroblast growth factor 14 0.065
Mmp3 matrix metallopeptidase 3 0.065
Sstr5 somatostatin receptor 5 0.065
LOC689064 beta-globin 0.064
Atp7b ATPase, Cu++ transporting, beta polypeptide 0.063
Dnah1 dynein, axonemal, heavy chain 1 0.063
Ptafr platelet-activating factor receptor 0.061
C5ar1 complement component 5a receptor 1 0.060
LOC60591 calcium-activated potassium channel beta subunit 0.060
Olr416 olfactory receptor 416 0.057
Gast gastrin 0.056
Madcam1 mucosal vascular addressin cell adhesion molecule 1 0.055
Apoa5 apolipoprotein A-V 0.054
Tore trispanning orphan 0.053
Gpr88 G-protein coupled receptor 88 0.053
Hes2 hairy and enhancer of split 2 (Drosophila) 0.052
Atp12a ATPase, H+/K+ transporting, nongastric, alpha polypeptide 0.051
Abcc2 ATP-binding cassette, subfamily C (CFTR/MRP), member 2 0.050
Drd1a dopamine receptor D1A 0.050
Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 0.049
Grin2b glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.049
Ptger2 prostaglandin E receptor 2 (subtype EP2) 0.049
Tbx2 T-box 2 0.049
Grik1 glutamate receptor, ionotropic, kainate 1 0.049
Slc6a7 solute carrier family 6 (neurotransmitter transporter, L-proline), member 7 0.048
Lif leukemia inhibitory factor 0.048
Pdc phosducin 0.048
Plcd4 phospholipase C, delta 4 0.048
Il9r interleukin 9 receptor 0.048
Adam2 ADAM metallopeptidase domain 2 0.048
Sstr1 somatostatin receptor 1 0.048
Rorb RAR-related orphan receptor B 0.047
Fshb follicle stimulating hormone, beta polypeptide 0.047
Acmsd aminocarboxymuconate semialdehyde decarboxylase 0.047
Nxph4 neurexophilin 4 0.047
Nmbr neuromedin B receptor 0.046
Gstm3 glutathione S-transferase mu 3 0.046
Gnrhr gonadotropin releasing hormone receptor 0.046
Olr442 olfactory receptor 442 0.046
Acr acrosin 0.046
RGD1560559 similar to RIKEN cDNA 2310042E22 0.046
Dhrs9 dehydrogenase/reductase (SDR family) member 9 0.046
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism