IMP

Process View

Homo sapiens

1 genes annotated in human

Multi-species View

positive regulation of granzyme a production

GO:2000513

Any process that activates or increases the frequency, rate or extent of granzyme A production.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in human Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of granzyme a production"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of granzyme a production" (in gray)

Name	Description	Probability	Func Analog Organism
CCR5	chemokine (C-C motif) receptor 5	0.998
CCL2	chemokine (C-C motif) ligand 2	0.980	Human
IL8	interleukin 8	0.973
CCL4	chemokine (C-C motif) ligand 4	0.949	Human
CXCL9	chemokine (C-X-C motif) ligand 9	0.858
CXCL2	chemokine (C-X-C motif) ligand 2	0.809
CCL8	chemokine (C-C motif) ligand 8	0.750	Human
CXCL3	chemokine (C-X-C motif) ligand 3	0.736
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.716	Human
DPP4	dipeptidyl-peptidase 4	0.712
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.638
CCL5	chemokine (C-C motif) ligand 5	0.599	Human
CCL13	chemokine (C-C motif) ligand 13	0.537	Human
CXCL10	chemokine (C-X-C motif) ligand 10	0.453
CXCL11	chemokine (C-X-C motif) ligand 11	0.433
IDE	insulin-degrading enzyme	0.428
IL1B	interleukin 1, beta	0.359
CCR7	chemokine (C-C motif) receptor 7	0.337
CCL19	chemokine (C-C motif) ligand 19	0.268	Human
IFNG	interferon, gamma	0.199
CCL3	chemokine (C-C motif) ligand 3	0.146	Human
CXCL13	chemokine (C-X-C motif) ligand 13	0.145
GZMB	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)	0.136
CCL22	chemokine (C-C motif) ligand 22	0.128	Human
IL10	interleukin 10	0.121
IL2RB	interleukin 2 receptor, beta	0.118
CD83	CD83 molecule	0.109
IL6	interleukin 6 (interferon, beta 2)	0.102
CCL7	chemokine (C-C motif) ligand 7	0.092	Human
CCR4	chemokine (C-C motif) receptor 4	0.086
CCR1	chemokine (C-C motif) receptor 1	0.081
VCAM1	vascular cell adhesion molecule 1	0.079
RGS1	regulator of G-protein signaling 1	0.076
BCL2A1	BCL2-related protein A1	0.073
CCL11	chemokine (C-C motif) ligand 11	0.070	Human
ICAM1	intercellular adhesion molecule 1	0.057
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.054
SELE	selectin E	0.052
UBD	ubiquitin D	0.050
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.049
IL7R	interleukin 7 receptor	0.048
CH25H	cholesterol 25-hydroxylase	0.045
LAMP3	lysosomal-associated membrane protein 3	0.041
KLRD1	killer cell lectin-like receptor subfamily D, member 1	0.039
GNLY	granulysin	0.037
AKT2	v-akt murine thymoma viral oncogene homolog 2	0.037
FPR3	formyl peptide receptor 3	0.036
STAT4	signal transducer and activator of transcription 4	0.035
TNF	tumor necrosis factor	0.035
CXCR6	chemokine (C-X-C motif) receptor 6	0.035
IL1RN	interleukin 1 receptor antagonist	0.034
CXCL5	chemokine (C-X-C motif) ligand 5	0.032
TRAF1	TNF receptor-associated factor 1	0.031
IL2RG	interleukin 2 receptor, gamma	0.029
KLRB1	killer cell lectin-like receptor subfamily B, member 1	0.028
SLAMF7	SLAM family member 7	0.028
ADAMDEC1	ADAM-like, decysin 1	0.026
IDO1	indoleamine 2,3-dioxygenase 1	0.025
XCL1	chemokine (C motif) ligand 1	0.025
DARC	Duffy blood group, chemokine receptor	0.025
CD80	CD80 molecule	0.023
SLAMF8	SLAM family member 8	0.021
CD69	CD69 molecule	0.021
EBI3	Epstein-Barr virus induced 3	0.020
XCL2	chemokine (C motif) ligand 2	0.019	Human
CXCR3	chemokine (C-X-C motif) receptor 3	0.019
IL32	interleukin 32	0.019
CCR3	chemokine (C-C motif) receptor 3	0.018
IL18RAP	interleukin 18 receptor accessory protein	0.018
SLAMF1	signaling lymphocytic activation molecule family member 1	0.018
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.018
IL1A	interleukin 1, alpha	0.018
IL21R	interleukin 21 receptor	0.018
IL12B	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)	0.018
NKG7	natural killer cell group 7 sequence	0.017
CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.017
OLR1	oxidized low density lipoprotein (lectin-like) receptor 1	0.016
ARRB1	arrestin, beta 1	0.016
TNFAIP6	tumor necrosis factor, alpha-induced protein 6	0.015
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.015
HLA-DRB4	major histocompatibility complex, class II, DR beta 4	0.014
BATF	basic leucine zipper transcription factor, ATF-like	0.014
CCL20	chemokine (C-C motif) ligand 20	0.014	Human
GZMK	granzyme K (granzyme 3; tryptase II)	0.014
LTA	lymphotoxin alpha (TNF superfamily, member 1)	0.014
IL2RA	interleukin 2 receptor, alpha	0.014
IL1R2	interleukin 1 receptor, type II	0.014
RGS16	regulator of G-protein signaling 16	0.014
HSD11B1	hydroxysteroid (11-beta) dehydrogenase 1	0.013
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.013
NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.013
GPR171	G protein-coupled receptor 171	0.012
CD40	CD40 molecule, TNF receptor superfamily member 5	0.012
MSC	musculin	0.012
INHBA	inhibin, beta A	0.012
CD160	CD160 molecule	0.011
ITK	IL2-inducible T-cell kinase	0.011
IRF4	interferon regulatory factor 4	0.011
CCRL2	chemokine (C-C motif) receptor-like 2	0.011
AQP9	aquaporin 9	0.011
C2	complement component 2	0.011
PLEK	pleckstrin	0.010
APOC1	apolipoprotein C-I	0.010
KLRK1	killer cell lectin-like receptor subfamily K, member 1	0.010