IMP
Process View
negative regulation of epithelial to mesenchymal transition
Any process that decreases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of epithelial to mesenchymal transition"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| POU5F1 | POU class 5 homeobox 1 | 0.797 | ||
| PPP2CB | protein phosphatase 2, catalytic subunit, beta isozyme | 0.602 | Human | |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta | 0.582 | ||
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | 0.567 | ||
| TBX5 | T-box 5 | 0.537 | ||
| GATA4 | GATA binding protein 4 | 0.314 | ||
| PRKCZ | protein kinase C, zeta | 0.113 | ||
| SMN1 | survival of motor neuron 1, telomeric | 0.086 | ||
| PAX8 | paired box 8 | 0.073 | ||
| CTTNBP2NL | CTTNBP2 N-terminal like | 0.066 | ||
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.063 | ||
| REV3L | REV3-like, catalytic subunit of DNA polymerase zeta (yeast) | 0.050 | ||
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | 0.050 | ||
| ADAM9 | ADAM metallopeptidase domain 9 | 0.046 | ||
| TBX1 | T-box 1 | 0.040 | ||
| STK24 | serine/threonine kinase 24 | 0.038 | ||
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.037 | ||
| SOX2 | SRY (sex determining region Y)-box 2 | 0.034 | ||
| ETF1 | eukaryotic translation termination factor 1 | 0.032 | ||
| FAM40A | family with sequence similarity 40, member A | 0.030 | ||
| STRN | striatin, calmodulin binding protein | 0.027 | ||
| LBX1 | ladybird homeobox 1 | 0.027 | ||
| PARD6B | par-6 partitioning defective 6 homolog beta (C. elegans) | 0.027 | ||
| PDX1 | pancreatic and duodenal homeobox 1 | 0.025 | ||
| STRN3 | striatin, calmodulin binding protein 3 | 0.025 | ||
| GEMIN6 | gem (nuclear organelle) associated protein 6 | 0.023 | ||
| CDX2 | caudal type homeobox 2 | 0.022 | ||
| IMMT | inner membrane protein, mitochondrial | 0.022 | ||
| CALCA | calcitonin-related polypeptide alpha | 0.021 | ||
| FOXC2 | forkhead box C2 (MFH-1, mesenchyme forkhead 1) | 0.020 | Human | |
| MNX1 | motor neuron and pancreas homeobox 1 | 0.020 | ||
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 | 0.019 | ||
| PPP2R5D | protein phosphatase 2, regulatory subunit B', delta | 0.019 | ||
| RBPMS | RNA binding protein with multiple splicing | 0.018 | ||
| INHBB | inhibin, beta B | 0.018 | ||
| BHLHE23 | basic helix-loop-helix family, member e23 | 0.017 | ||
| CCDC90B | coiled-coil domain containing 90B | 0.017 | ||
| ELK1 | ELK1, member of ETS oncogene family | 0.016 | ||
| PTF1A | pancreas specific transcription factor, 1a | 0.016 | ||
| SOX1 | SRY (sex determining region Y)-box 1 | 0.016 | ||
| MUC4 | mucin 4, cell surface associated | 0.016 | ||
| FOXA2 | forkhead box A2 | 0.015 | ||
| AXIN2 | axin 2 | 0.015 | ||
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.014 | ||
| HOXD9 | homeobox D9 | 0.014 | ||
| GSPT1 | G1 to S phase transition 1 | 0.013 | ||
| NKX2-8 | NK2 homeobox 8 | 0.013 | Human | |
| FOXF1 | forkhead box F1 | 0.013 | ||
| GATA5 | GATA binding protein 5 | 0.013 | ||
| FOXF2 | forkhead box F2 | 0.013 | ||
| AR | androgen receptor | 0.013 | ||
| SLC18A3 | solute carrier family 18 (vesicular acetylcholine), member 3 | 0.013 | ||
| NKX6-1 | NK6 homeobox 1 | 0.013 | ||
| SLMAP | sarcolemma associated protein | 0.012 | ||
| LHX1 | LIM homeobox 1 | 0.012 | ||
| FOXD3 | forkhead box D3 | 0.012 | Human | |
| FXYD3 | FXYD domain containing ion transport regulator 3 | 0.012 | ||
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) | 0.012 | ||
| PPP4C | protein phosphatase 4, catalytic subunit | 0.012 | ||
| TP73 | tumor protein p73 | 0.012 | ||
| ONECUT1 | one cut homeobox 1 | 0.012 | ||
| ZNF775 | zinc finger protein 775 | 0.012 | ||
| WDYHV1 | WDYHV motif containing 1 | 0.012 | ||
| TBX2 | T-box 2 | 0.012 | ||
| FGF3 | fibroblast growth factor 3 | 0.012 | ||
| WFDC2 | WAP four-disulfide core domain 2 | 0.011 | ||
| HIC1 | hypermethylated in cancer 1 | 0.011 | ||
| PITX2 | paired-like homeodomain 2 | 0.011 | ||
| SIX2 | SIX homeobox 2 | 0.011 | ||
| NKX2-1 | NK2 homeobox 1 | 0.011 | ||
| FOXE1 | forkhead box E1 (thyroid transcription factor 2) | 0.011 | Human | |
| HOXD1 | homeobox D1 | 0.011 | ||
| AMN | amnionless homolog (mouse) | 0.011 | ||
| SH3BP4 | SH3-domain binding protein 4 | 0.011 | ||
| RAB17 | RAB17, member RAS oncogene family | 0.011 | ||
| HOXB13 | homeobox B13 | 0.011 | ||
| FOXH1 | forkhead box H1 | 0.010 | ||
| FOXL1 | forkhead box L1 | 0.010 | Human | |
| PRR15L | proline rich 15-like | 0.010 | ||
| FZD8 | frizzled homolog 8 (Drosophila) | 0.010 | ||
| ZNF828 | zinc finger protein 828 | 0.010 | ||
| FEV | FEV (ETS oncogene family) | 0.010 |