IMP
Process View
fc receptor mediated inhibitory signaling pathway
A series of molecular signals generated as a consequence of the binding of the Fc portion of an immunoglobulin by an Fc receptor capable of inhibiting an immune effector process contributing to an immune response. The Fc portion of an immunoglobulin is its C-terminal constant region.
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Click on a gene's description to view its network relationships with genes known to be involved in "fc receptor mediated inhibitory signaling pathway"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| LILRA6 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 | 1.000 | ||
| LILRB1 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 | 1.000 | ||
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 | 1.000 | Human | |
| PILRA | paired immunoglobin-like type 2 receptor alpha | 0.999 | ||
| LILRB2 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 | 0.999 | ||
| LILRA1 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 | 0.943 | Human | |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 | 0.934 | ||
| LILRA2 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 | 0.849 | ||
| PTPN6 | protein tyrosine phosphatase, non-receptor type 6 | 0.828 | ||
| PTAFR | platelet-activating factor receptor | 0.820 | ||
| HK3 | hexokinase 3 (white cell) | 0.763 | ||
| TYMP | thymidine phosphorylase | 0.532 | ||
| CD33 | CD33 molecule | 0.334 | ||
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 | 0.133 | ||
| AOAH | acyloxyacyl hydrolase (neutrophil) | 0.129 | ||
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 | 0.108 | ||
| TREM1 | triggering receptor expressed on myeloid cells 1 | 0.102 | ||
| CSK | c-src tyrosine kinase | 0.078 | ||
| SIRPB1 | signal-regulatory protein beta 1 | 0.075 | ||
| LILRA3 | leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3 | 0.074 | Human | |
| CCR1 | chemokine (C-C motif) receptor 1 | 0.070 | ||
| CD86 | CD86 molecule | 0.068 | ||
| NLRP3 | NLR family, pyrin domain containing 3 | 0.064 | ||
| SIGLEC1 | sialic acid binding Ig-like lectin 1, sialoadhesin | 0.063 | ||
| SIGLEC9 | sialic acid binding Ig-like lectin 9 | 0.061 | ||
| SPI1 | spleen focus forming virus (SFFV) proviral integration oncogene spi1 | 0.054 | ||
| CYTH4 | cytohesin 4 | 0.052 | ||
| LAIR1 | leukocyte-associated immunoglobulin-like receptor 1 | 0.051 | Human | |
| DOCK7 | dedicator of cytokinesis 7 | 0.046 | ||
| CD300A | CD300a molecule | 0.046 | ||
| VSIG4 | V-set and immunoglobulin domain containing 4 | 0.044 | ||
| AIF1 | allograft inflammatory factor 1 | 0.042 | ||
| CD300C | CD300c molecule | 0.042 | ||
| FPR2 | formyl peptide receptor 2 | 0.040 | ||
| HCK | hemopoietic cell kinase | 0.034 | ||
| TLR8 | toll-like receptor 8 | 0.033 | ||
| NOD2 | nucleotide-binding oligomerization domain containing 2 | 0.032 | ||
| MARCO | macrophage receptor with collagenous structure | 0.031 | ||
| LILRB4 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 | 0.030 | Human | |
| CD163 | CD163 molecule | 0.029 | ||
| DPEP2 | dipeptidase 2 | 0.028 | ||
| FPR1 | formyl peptide receptor 1 | 0.028 | ||
| FCGR2C | Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) | 0.027 | ||
| SLC15A3 | solute carrier family 15, member 3 | 0.026 | ||
| EMR1 | egf-like module containing, mucin-like, hormone receptor-like 1 | 0.024 | ||
| RASSF4 | Ras association (RalGDS/AF-6) domain family member 4 | 0.022 | ||
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) | 0.022 | ||
| CFP | complement factor properdin | 0.021 | ||
| CMKLR1 | chemokine-like receptor 1 | 0.019 | ||
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.019 | ||
| LILRA5 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 | 0.018 | Human | |
| FCGR3B | Fc fragment of IgG, low affinity IIIb, receptor (CD16b) | 0.018 | ||
| AQP9 | aquaporin 9 | 0.018 | ||
| SIGLEC5 | sialic acid binding Ig-like lectin 5 | 0.017 | ||
| PIK3R5 | phosphoinositide-3-kinase, regulatory subunit 5 | 0.016 | ||
| HLA-G | major histocompatibility complex, class I, G | 0.016 | ||
| SIRPA | signal-regulatory protein alpha | 0.016 | ||
| S100A12 | S100 calcium binding protein A12 | 0.016 | ||
| CASP5 | caspase 5, apoptosis-related cysteine peptidase | 0.016 | ||
| BIN2 | bridging integrator 2 | 0.016 | ||
| CLEC5A | C-type lectin domain family 5, member A | 0.016 | ||
| IL1RN | interleukin 1 receptor antagonist | 0.015 | ||
| APOBR | apolipoprotein B receptor | 0.014 | ||
| PSTPIP1 | proline-serine-threonine phosphatase interacting protein 1 | 0.013 | ||
| IGSF6 | immunoglobulin superfamily, member 6 | 0.013 | ||
| ASGR2 | asialoglycoprotein receptor 2 | 0.013 | ||
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) | 0.012 | ||
| EMR3 | egf-like module containing, mucin-like, hormone receptor-like 3 | 0.012 | ||
| FCAR | Fc fragment of IgA, receptor for | 0.012 | Human | |
| EPOR | erythropoietin receptor | 0.011 | ||
| CSF3R | colony stimulating factor 3 receptor (granulocyte) | 0.011 | ||
| CYBB | cytochrome b-245, beta polypeptide | 0.011 | ||
| BEST1 | bestrophin 1 | 0.011 | ||
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | 0.011 | ||
| HAMP | hepcidin antimicrobial peptide | 0.011 | ||
| FOLR3 | folate receptor 3 (gamma) | 0.010 |