IMP

Process View

Homo sapiens

4 genes annotated in human

regulation of mhc class ii biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of mhc class ii biosynthetic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of mhc class ii biosynthetic process" (in gray)

Name	Description	Probability	Func Analog Organism
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.988	Human
CXCL10	chemokine (C-X-C motif) ligand 10	0.937	Human
CXCL11	chemokine (C-X-C motif) ligand 11	0.887	Human
CXCL5	chemokine (C-X-C motif) ligand 5	0.715	Human
CXCL2	chemokine (C-X-C motif) ligand 2	0.674
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.668
IL8	interleukin 8	0.653
IL4R	interleukin 4 receptor	0.406
PF4	platelet factor 4	0.377
DPP4	dipeptidyl-peptidase 4	0.321
IL2RG	interleukin 2 receptor, gamma	0.212
TICAM2	toll-like receptor adaptor molecule 2	0.184
LY96	lymphocyte antigen 96	0.156
CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.156	Human
HBA2	hemoglobin, alpha 2	0.150
CCL8	chemokine (C-C motif) ligand 8	0.146
MPO	myeloperoxidase	0.100
ITGA2B	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)	0.085
PPBP	pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)	0.082	Human
PF4V1	platelet factor 4 variant 1	0.076	Human
S100A12	S100 calcium binding protein A12	0.074
CCL20	chemokine (C-C motif) ligand 20	0.056
CXCR3	chemokine (C-X-C motif) receptor 3	0.052
IDO1	indoleamine 2,3-dioxygenase 1	0.051
TFEC	transcription factor EC	0.045
BPI	bactericidal/permeability-increasing protein	0.042
GFI1	growth factor independent 1 transcription repressor	0.042
NFE2	nuclear factor (erythroid-derived 2), 45kDa	0.036
MS4A3	membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)	0.035
CCL7	chemokine (C-C motif) ligand 7	0.034
HBD	hemoglobin, delta	0.032
PSMA5	proteasome (prosome, macropain) subunit, alpha type, 5	0.031
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.030
LCN2	lipocalin 2	0.028
CXCL13	chemokine (C-X-C motif) ligand 13	0.028
APOBR	apolipoprotein B receptor	0.028
PLEK	pleckstrin	0.026
IFNG	interferon, gamma	0.026
MOBKL2B	MOB1, Mps One Binder kinase activator-like 2B (yeast)	0.025
APOL1	apolipoprotein L, 1	0.025
STAT6	signal transducer and activator of transcription 6, interleukin-4 induced	0.025
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.024
CXCL3	chemokine (C-X-C motif) ligand 3	0.023	Human
LAMP3	lysosomal-associated membrane protein 3	0.023
CEBPA	CCAAT/enhancer binding protein (C/EBP), alpha	0.023
HBB	hemoglobin, beta	0.022
SELE	selectin E	0.022
IL15RA	interleukin 15 receptor, alpha	0.022
UBD	ubiquitin D	0.022
CTSG	cathepsin G	0.022
IL6	interleukin 6 (interferon, beta 2)	0.021
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.020
EFNA1	ephrin-A1	0.020
APOL3	apolipoprotein L, 3	0.020
RSAD2	radical S-adenosyl methionine domain containing 2	0.019
CCL2	chemokine (C-C motif) ligand 2	0.019
IFIT2	interferon-induced protein with tetratricopeptide repeats 2	0.019
CLEC4G	C-type lectin domain family 4, member G	0.018
IL10	interleukin 10	0.018
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.018
GBP4	guanylate binding protein 4	0.018
GPR97	G protein-coupled receptor 97	0.018
CH25H	cholesterol 25-hydroxylase	0.017
VCAM1	vascular cell adhesion molecule 1	0.017
IFI27	interferon, alpha-inducible protein 27	0.017
ALAS2	aminolevulinate, delta-, synthase 2	0.016
CLC	Charcot-Leyden crystal protein	0.016
RARA	retinoic acid receptor, alpha	0.016
HOXA10	homeobox A10	0.016
CXCL9	chemokine (C-X-C motif) ligand 9	0.016	Human
KLF1	Kruppel-like factor 1 (erythroid)	0.016
PRG2	proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)	0.016
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.016
RNASE3	ribonuclease, RNase A family, 3	0.015
RPS27	ribosomal protein S27	0.015
DEFA4	defensin, alpha 4, corticostatin	0.015
GP5	glycoprotein V (platelet)	0.015
BIRC3	baculoviral IAP repeat containing 3	0.015
CAMP	cathelicidin antimicrobial peptide	0.015
IFI44L	interferon-induced protein 44-like	0.014
GATA1	GATA binding protein 1 (globin transcription factor 1)	0.014
POU2F2	POU class 2 homeobox 2	0.014
AZU1	azurocidin 1	0.014
IL11	interleukin 11	0.014
HP	haptoglobin	0.014
CMTM6	CKLF-like MARVEL transmembrane domain containing 6	0.014
EP300	E1A binding protein p300	0.013
MMP7	matrix metallopeptidase 7 (matrilysin, uterine)	0.013
ALB	albumin	0.013
HIPK2	homeodomain interacting protein kinase 2	0.013
NRGN	neurogranin (protein kinase C substrate, RC3)	0.013
IL15	interleukin 15	0.013
VPREB1	pre-B lymphocyte 1	0.012
MMP8	matrix metallopeptidase 8 (neutrophil collagenase)	0.012
SERPINA1	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1	0.012
RARRES1	retinoic acid receptor responder (tazarotene induced) 1	0.012
MESDC2	mesoderm development candidate 2	0.012
OASL	2'-5'-oligoadenylate synthetase-like	0.011
CEACAM8	carcinoembryonic antigen-related cell adhesion molecule 8	0.011
S100A8	S100 calcium binding protein A8	0.011
TLR1	toll-like receptor 1	0.011
CCL13	chemokine (C-C motif) ligand 13	0.011
LTF	lactotransferrin	0.011
MMP10	matrix metallopeptidase 10 (stromelysin 2)	0.011
CCL19	chemokine (C-C motif) ligand 19	0.011
CCL4	chemokine (C-C motif) ligand 4	0.011
HBG2	hemoglobin, gamma G	0.011
FOLR3	folate receptor 3 (gamma)	0.011
LIPG	lipase, endothelial	0.010
OAS2	2'-5'-oligoadenylate synthetase 2, 69/71kDa	0.010
HERPUD1	homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1	0.010