IMP

Process View

Homo sapiens

4 genes annotated in human

positive regulation of mhc class i biosynthetic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class I.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of mhc class i biosynthetic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of mhc class i biosynthetic process" (in gray)

Name	Description	Probability	Func Analog Organism
RIPK2	receptor-interacting serine-threonine kinase 2	1.000
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.912
CASP1	caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)	0.553
BIRC3	baculoviral IAP repeat containing 3	0.516
ANG	angiogenin, ribonuclease, RNase A family, 5	0.245
BTN3A1	butyrophilin, subfamily 3, member A1	0.126
TRAF3	TNF receptor-associated factor 3	0.120
PYDC2	pyrin domain containing 2	0.105
GBP5	guanylate binding protein 5	0.088
HCP5	HLA complex P5	0.084
NLRC4	NLR family, CARD domain containing 4	0.076
CASP9	caspase 9, apoptosis-related cysteine peptidase	0.071
FCAR	Fc fragment of IgA, receptor for	0.046
NOD1	nucleotide-binding oligomerization domain containing 1	0.044	Human
TAP1	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)	0.041
NOD2	nucleotide-binding oligomerization domain containing 2	0.038	Human
LILRB2	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2	0.035
TRAF1	TNF receptor-associated factor 1	0.035
TP53BP1	tumor protein p53 binding protein 1	0.030
KIF2B	kinesin family member 2B	0.026
RASAL3	RAS protein activator like 3	0.026
LILRA1	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1	0.025
LY86	lymphocyte antigen 86	0.025
CCDC108	coiled-coil domain containing 108	0.022
PILRA	paired immunoglobin-like type 2 receptor alpha	0.022
PYCARD	PYD and CARD domain containing	0.022
TAS2R38	taste receptor, type 2, member 38	0.021
BIRC2	baculoviral IAP repeat containing 2	0.020
ZAN	zonadhesin	0.019
PARP12	poly (ADP-ribose) polymerase family, member 12	0.019
SIRPD	signal-regulatory protein delta	0.019
TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	0.018
HEATR7B2	HEAT repeat family member 7B2	0.017
C17orf87	chromosome 17 open reading frame 87	0.016
OR10A4	olfactory receptor, family 10, subfamily A, member 4	0.016
NLRP13	NLR family, pyrin domain containing 13	0.016	Human
NLRP8	NLR family, pyrin domain containing 8	0.015	Human
MAVS	mitochondrial antiviral signaling protein	0.015
CARD18	caspase recruitment domain family, member 18	0.015
SIGLEC7	sialic acid binding Ig-like lectin 7	0.014
LILRB1	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1	0.014
FPR2	formyl peptide receptor 2	0.013
GPR84	G protein-coupled receptor 84	0.013
ITGAD	integrin, alpha D	0.013
OR52D1	olfactory receptor, family 52, subfamily D, member 1	0.013
SLC15A3	solute carrier family 15, member 3	0.013
OR51B2	olfactory receptor, family 51, subfamily B, member 2	0.013
MEFV	Mediterranean fever	0.013
SIRPB1	signal-regulatory protein beta 1	0.013
FAM71C	family with sequence similarity 71, member C	0.013
NLRP10	NLR family, pyrin domain containing 10	0.013	Human
XAGE3	X antigen family, member 3	0.013
AIM2	absent in melanoma 2	0.012
NLRP11	NLR family, pyrin domain containing 11	0.012	Human
WFDC10A	WAP four-disulfide core domain 10A	0.012
SPATA16	spermatogenesis associated 16	0.012
CLEC4F	C-type lectin domain family 4, member F	0.012
IL1B	interleukin 1, beta	0.012
ZNF645	zinc finger protein 645	0.012
C17orf47	chromosome 17 open reading frame 47	0.012
FCGR2C	Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)	0.012
PNPLA1	patatin-like phospholipase domain containing 1	0.012
SPINK6	serine peptidase inhibitor, Kazal type 6	0.012
WFDC11	WAP four-disulfide core domain 11	0.012
IGFL1	IGF-like family member 1	0.012
RNF213	ring finger protein 213	0.012
GPR112	G protein-coupled receptor 112	0.012
UCMA	upper zone of growth plate and cartilage matrix associated	0.011
FAM47A	family with sequence similarity 47, member A	0.011
NLRP4	NLR family, pyrin domain containing 4	0.011	Human
RHBDF2	rhomboid 5 homolog 2 (Drosophila)	0.011
DGKK	diacylglycerol kinase, kappa	0.011
WNT8A	wingless-type MMTV integration site family, member 8A	0.011
KRT82	keratin 82	0.011
SLC26A9	solute carrier family 26, member 9	0.011
KRTAP11-1	keratin associated protein 11-1	0.011
WFDC12	WAP four-disulfide core domain 12	0.011
ERVFRDE1	HERV-FRD provirus ancestral Env polyprotein	0.011
APAF1	apoptotic peptidase activating factor 1	0.011
C12orf69	chromosome 12 open reading frame 69	0.011
TMCO2	transmembrane and coiled-coil domains 2	0.011
SLC22A9	solute carrier family 22 (organic anion transporter), member 9	0.011
NXF5	nuclear RNA export factor 5	0.011
LCE3D	late cornified envelope 3D	0.011
PREX1	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1	0.011
TXNDC3	thioredoxin domain containing 3 (spermatozoa)	0.011
NHLRC4	NHL repeat containing 4	0.011
GPRC6A	G protein-coupled receptor, family C, group 6, member A	0.011
PTAFR	platelet-activating factor receptor	0.011
HSPA6	heat shock 70kDa protein 6 (HSP70B')	0.011
EMR2	egf-like module containing, mucin-like, hormone receptor-like 2	0.011
S100Z	S100 calcium binding protein Z	0.011
NUP210L	nucleoporin 210kDa-like	0.011
TNFRSF13C	tumor necrosis factor receptor superfamily, member 13C	0.011
P2RX7	purinergic receptor P2X, ligand-gated ion channel, 7	0.011
SOHLH1	spermatogenesis and oogenesis specific basic helix-loop-helix 1	0.011
TERF2	telomeric repeat binding factor 2	0.010
DEFB125	defensin, beta 125	0.010
ADAMTS18	ADAM metallopeptidase with thrombospondin type 1 motif, 18	0.010
UBL4B	ubiquitin-like 4B	0.010
C5AR1	complement component 5a receptor 1	0.010
NLRP9	NLR family, pyrin domain containing 9	0.010	Human
RASSF4	Ras association (RalGDS/AF-6) domain family member 4	0.010
PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	0.010
DNAH8	dynein, axonemal, heavy chain 8	0.010
SERPINA9	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9	0.010
FAM154A	family with sequence similarity 154, member A	0.010
FKBP5	FK506 binding protein 5	0.010
C12orf12	chromosome 12 open reading frame 12	0.010
ZAR1	zygote arrest 1	0.010
CIB4	calcium and integrin binding family member 4	0.010
NHSL2	NHS-like 2	0.010
IL17F	interleukin 17F	0.010
TAS2R39	taste receptor, type 2, member 39	0.010
TREM1	triggering receptor expressed on myeloid cells 1	0.010
SPRR2G	small proline-rich protein 2G	0.010
GNGT2	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2	0.010
CCDC105	coiled-coil domain containing 105	0.010
ZIC5	Zic family member 5 (odd-paired homolog, Drosophila)	0.010
APOL6	apolipoprotein L, 6	0.010