IMP

Process View

Homo sapiens

14 genes annotated in human

Multi-species View

negative regulation of leukocyte migration

GO:0002686

Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte migration.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of leukocyte migration"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of leukocyte migration" (in gray)

Name	Description	Probability	Func Analog Organism
HOXB5	homeobox B5	0.993	Human
HOXA10	homeobox A10	0.612
PTGIR	prostaglandin I2 (prostacyclin) receptor (IP)	0.538	Human
CCL19	chemokine (C-C motif) ligand 19	0.518	Human
HOXB6	homeobox B6	0.500	Human
CCL5	chemokine (C-C motif) ligand 5	0.499	Human
TFF1	trefoil factor 1	0.464
CCR5	chemokine (C-C motif) receptor 5	0.464
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.444	Human
APOE	apolipoprotein E	0.407
CCL4	chemokine (C-C motif) ligand 4	0.406	Human
C19orf50	chromosome 19 open reading frame 50	0.396
CFH	complement factor H	0.340
HOXA4	homeobox A4	0.320	Human
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.282
HOXB9	homeobox B9	0.254
HOXB3	homeobox B3	0.246
HOXB7	homeobox B7	0.245	Human
CCL2	chemokine (C-C motif) ligand 2	0.222
TBXA2R	thromboxane A2 receptor	0.203	Human
WHSC1L1	Wolf-Hirschhorn syndrome candidate 1-like 1	0.201
DPP4	dipeptidyl-peptidase 4	0.181
TGM2	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	0.176
HOXA6	homeobox A6	0.151	Human
IDE	insulin-degrading enzyme	0.115
CCL13	chemokine (C-C motif) ligand 13	0.112	Human
HOXC6	homeobox C6	0.111	Human
IL1B	interleukin 1, beta	0.109
CCR7	chemokine (C-C motif) receptor 7	0.106
CXCL9	chemokine (C-X-C motif) ligand 9	0.102
CCL8	chemokine (C-C motif) ligand 8	0.091	Human
CCL3	chemokine (C-C motif) ligand 3	0.076	Human
HOXC10	homeobox C10	0.073
HOXA11	homeobox A11	0.069
HOXA2	homeobox A2	0.064
HOXC4	homeobox C4	0.063	Human
HOXA5	homeobox A5	0.063	Human
DARC	Duffy blood group, chemokine receptor	0.060
CCR4	chemokine (C-C motif) receptor 4	0.059
HOXA3	homeobox A3	0.049
CCR1	chemokine (C-C motif) receptor 1	0.048
DPT	dermatopontin	0.046
ADORA2A	adenosine A2a receptor	0.045
FBLN1	fibulin 1	0.044
PTGDS	prostaglandin D2 synthase 21kDa (brain)	0.042
RGS1	regulator of G-protein signaling 1	0.041
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.040
CCL21	chemokine (C-C motif) ligand 21	0.038
HOXA7	homeobox A7	0.038
VCAM1	vascular cell adhesion molecule 1	0.038
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.037
ARRB1	arrestin, beta 1	0.035
CFI	complement factor I	0.033
TNF	tumor necrosis factor	0.032
HLA-DPA1	major histocompatibility complex, class II, DP alpha 1	0.030
RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	0.029
CD74	CD74 molecule, major histocompatibility complex, class II invariant chain	0.027
PRDX4	peroxiredoxin 4	0.027
IL8	interleukin 8	0.027
CH25H	cholesterol 25-hydroxylase	0.026
GHRL	ghrelin/obestatin prepropeptide	0.026
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.026
CCL7	chemokine (C-C motif) ligand 7	0.025	Human
IL10	interleukin 10	0.025
IL6	interleukin 6 (interferon, beta 2)	0.024
NKG7	natural killer cell group 7 sequence	0.023
SIGLEC7	sialic acid binding Ig-like lectin 7	0.023
PTGIS	prostaglandin I2 (prostacyclin) synthase	0.023
AKT2	v-akt murine thymoma viral oncogene homolog 2	0.023
CCL11	chemokine (C-C motif) ligand 11	0.022	Human
CXCL13	chemokine (C-X-C motif) ligand 13	0.022
HK3	hexokinase 3 (white cell)	0.021
VCAN	versican	0.021
HOXA1	homeobox A1	0.020
SELE	selectin E	0.020
MSC	musculin	0.020
C7	complement component 7	0.020
WISP2	WNT1 inducible signaling pathway protein 2	0.020
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.019
HOXC5	homeobox C5	0.019	Human
C1S	complement component 1, s subcomponent	0.019
HOXB4	homeobox B4	0.019	Human
CXCL11	chemokine (C-X-C motif) ligand 11	0.018
CFB	complement factor B	0.018
MYH11	myosin, heavy chain 11, smooth muscle	0.018
NNMT	nicotinamide N-methyltransferase	0.018
HOXB2	homeobox B2	0.018
HOXC9	homeobox C9	0.018
CXCL5	chemokine (C-X-C motif) ligand 5	0.017
IL10RA	interleukin 10 receptor, alpha	0.017
CCL22	chemokine (C-C motif) ligand 22	0.017	Human
HOXB8	homeobox B8	0.017	Human
ITGAX	integrin, alpha X (complement component 3 receptor 4 subunit)	0.016
MGP	matrix Gla protein	0.016
IL2RG	interleukin 2 receptor, gamma	0.016
SRGN	serglycin	0.016
HOXC11	homeobox C11	0.015
RARRES1	retinoic acid receptor responder (tazarotene induced) 1	0.015
IL21R	interleukin 21 receptor	0.015
PDZD3	PDZ domain containing 3	0.015
IL18RAP	interleukin 18 receptor accessory protein	0.015
SEPT8	septin 8	0.015
C5AR1	complement component 5a receptor 1	0.014
KRT81	keratin 81	0.014
COL14A1	collagen, type XIV, alpha 1	0.014
SMAD6	SMAD family member 6	0.014
HOXD8	homeobox D8	0.013	Human
IFNG	interferon, gamma	0.013
HOXC8	homeobox C8	0.013	Human
CCL3L3	chemokine (C-C motif) ligand 3-like 3	0.013
DCN	decorin	0.013
MXRA8	matrix-remodelling associated 8	0.013
FPR3	formyl peptide receptor 3	0.013
CCR3	chemokine (C-C motif) receptor 3	0.013
CD69	CD69 molecule	0.013
KRT15	keratin 15	0.013
EBI3	Epstein-Barr virus induced 3	0.012
DRD2	dopamine receptor D2	0.012
SOD3	superoxide dismutase 3, extracellular	0.012
CXCL12	chemokine (C-X-C motif) ligand 12	0.012
CCL1	chemokine (C-C motif) ligand 1	0.012	Human
IL2RB	interleukin 2 receptor, beta	0.011
GZMB	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)	0.011
CHI3L1	chitinase 3-like 1 (cartilage glycoprotein-39)	0.011
PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	0.011
SIGLEC9	sialic acid binding Ig-like lectin 9	0.011
CD83	CD83 molecule	0.011
SPDEF	SAM pointed domain containing ets transcription factor	0.011
TREM1	triggering receptor expressed on myeloid cells 1	0.011
IL12RB1	interleukin 12 receptor, beta 1	0.011
GGT5	gamma-glutamyltransferase 5	0.011
PDX1	pancreatic and duodenal homeobox 1	0.011
HOXD10	homeobox D10	0.011
IL2RA	interleukin 2 receptor, alpha	0.011
GNLY	granulysin	0.011
SLC11A1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.011
GNRH2	gonadotropin-releasing hormone 2	0.011
CCL23	chemokine (C-C motif) ligand 23	0.010	Human
SLAMF8	SLAM family member 8	0.010
CCND1	cyclin D1	0.010
IL12B	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)	0.010
COL13A1	collagen, type XIII, alpha 1	0.010
SASH3	SAM and SH3 domain containing 3	0.010
CXCL10	chemokine (C-X-C motif) ligand 10	0.010
SIGLEC8	sialic acid binding Ig-like lectin 8	0.010
HOXD3	homeobox D3	0.010