IMP
Process View
2 oxoglutarate metabolic process
The chemical reactions and pathways involving oxoglutarate, the dianion of 2-oxoglutaric acid. It is a key constituent of the TCA cycle and a key intermediate in amino-acid metabolism.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "2 oxoglutarate metabolic process"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.326 | ||
| INSR | insulin receptor | 0.202 | ||
| ACO2 | aconitase 2, mitochondrial | 0.181 | ||
| AIFM1 | apoptosis-inducing factor, mitochondrion-associated, 1 | 0.166 | ||
| PTPRB | protein tyrosine phosphatase, receptor type, B | 0.144 | ||
| IDH3A | isocitrate dehydrogenase 3 (NAD+) alpha | 0.115 | Rat | |
| UQCRC1 | ubiquinol-cytochrome c reductase core protein I | 0.096 | ||
| DLAT | dihydrolipoamide S-acetyltransferase | 0.084 | ||
| ATP5B | ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide | 0.083 | ||
| STAP2 | signal transducing adaptor family member 2 | 0.064 | ||
| PTPN3 | protein tyrosine phosphatase, non-receptor type 3 | 0.052 | ||
| SDHA | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | 0.051 | ||
| IL2RB | interleukin 2 receptor, beta | 0.036 | ||
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.035 | ||
| RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 | 0.034 | ||
| CYCS | cytochrome c, somatic | 0.032 | ||
| PTPN9 | protein tyrosine phosphatase, non-receptor type 9 | 0.023 | ||
| ABL1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.020 | ||
| IDH3G | isocitrate dehydrogenase 3 (NAD+) gamma | 0.019 | Rat | |
| PQBP1 | polyglutamine binding protein 1 | 0.018 | ||
| CRKL | v-crk sarcoma virus CT10 oncogene homolog (avian)-like | 0.018 | ||
| NDUFV1 | NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa | 0.018 | ||
| SLC25A11 | solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 | 0.017 | ||
| PTPN2 | protein tyrosine phosphatase, non-receptor type 2 | 0.017 | ||
| GOT2 | glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2) | 0.016 | ||
| FLII | flightless I homolog (Drosophila) | 0.015 | ||
| DGAT1 | diacylglycerol O-acyltransferase 1 | 0.015 | ||
| GOT1 | glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) | 0.014 | Mouse | |
| HSD17B4 | hydroxysteroid (17-beta) dehydrogenase 4 | 0.014 | ||
| BCKDHA | branched chain keto acid dehydrogenase E1, alpha polypeptide | 0.013 | ||
| COQ9 | coenzyme Q9 homolog (S. cerevisiae) | 0.013 | ||
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | 0.013 | Human | |
| NMI | N-myc (and STAT) interactor | 0.013 | ||
| OXA1L | oxidase (cytochrome c) assembly 1-like | 0.012 | ||
| DCXR | dicarbonyl/L-xylulose reductase | 0.012 | ||
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.012 | ||
| STAT5A | signal transducer and activator of transcription 5A | 0.012 | Mouse | |
| MDH2 | malate dehydrogenase 2, NAD (mitochondrial) | 0.011 | ||
| AIP | aryl hydrocarbon receptor interacting protein | 0.011 | ||
| JAK1 | Janus kinase 1 | 0.011 | ||
| MFN2 | mitofusin 2 | 0.010 | ||
| NDUFA9 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa | 0.010 |