Process View
The process by which the mitochondrial outer membrane becomes permeable to the passing of proteins and other molecules from the intermembrane space to the cytosol as part of a programmed cell death process.

In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "mitochondrial outer membrane permeabilization involved in programmed cell death"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| BCL2L11 | BCL2-like 11 (apoptosis facilitator) | 0.964 | Mouse | |
| MCL1 | myeloid cell leukemia sequence 1 (BCL2-related) | 0.952 | ||
| BCL2 | B-cell CLL/lymphoma 2 | 0.939 | ||
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.871 | ||
| BAX | BCL2-associated X protein | 0.800 | Mouse | |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.675 | Mouse | |
| BCL2L1 | BCL2-like 1 | 0.671 | ||
| JUN | jun proto-oncogene | 0.643 | Human | |
| BAK1 | BCL2-antagonist/killer 1 | 0.606 | ||
| JUNB | jun B proto-oncogene | 0.475 | Human | |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.472 | ||
| BECN1 | beclin 1, autophagy related | 0.369 | ||
| IER2 | immediate early response 2 | 0.333 | ||
| ATF3 | activating transcription factor 3 | 0.210 | ||
| BAD | BCL2-associated agonist of cell death | 0.175 | ||
| BID | BH3 interacting domain death agonist | 0.165 | Mouse | |
| FKBP8 | FK506 binding protein 8, 38kDa | 0.165 | ||
| MAPK8 | mitogen-activated protein kinase 8 | 0.122 | ||
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.117 | ||
| PXMP2 | peroxisomal membrane protein 2, 22kDa | 0.109 | ||
| PPP2R5B | protein phosphatase 2, regulatory subunit B', beta | 0.097 | ||
| DUSP1 | dual specificity phosphatase 1 | 0.084 | ||
| BIK | BCL2-interacting killer (apoptosis-inducing) | 0.071 | ||
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.067 | Human | |
| ZFP36 | zinc finger protein 36, C3H type, homolog (mouse) | 0.055 | ||
| RNF144B | ring finger protein 144B | 0.050 | ||
| TP53BP2 | tumor protein p53 binding protein, 2 | 0.042 | ||
| RNR2 | l-rRNA | 0.039 | ||
| HUWE1 | HECT, UBA and WWE domain containing 1 | 0.037 | ||
| AMBRA1 | autophagy/beclin-1 regulator 1 | 0.036 | ||
| EGR1 | early growth response 1 | 0.036 | ||
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.034 | ||
| BBC3 | BCL2 binding component 3 | 0.034 | ||
| UBE2I | ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) | 0.034 | ||
| JDP2 | Jun dimerization protein 2 | 0.032 | ||
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | 0.028 | ||
| PPP1R15A | protein phosphatase 1, regulatory (inhibitor) subunit 15A | 0.027 | ||
| BLOC1S3 | biogenesis of lysosomal organelles complex-1, subunit 3 | 0.025 | ||
| DDIT3 | DNA-damage-inducible transcript 3 | 0.024 | ||
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.024 | ||
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.023 | ||
| OCIAD1 | OCIA domain containing 1 | 0.022 | ||
| ZHX1 | zinc fingers and homeoboxes 1 | 0.021 | ||
| AXIN1 | axin 1 | 0.020 | ||
| TMEM11 | transmembrane protein 11 | 0.018 | ||
| MAFF | v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian) | 0.018 | ||
| DTNBP1 | dystrobrevin binding protein 1 | 0.017 | ||
| SLC25A3 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | 0.017 | ||
| MUTED | muted homolog (mouse) | 0.017 | ||
| FOSL1 | FOS-like antigen 1 | 0.017 | ||
| RDH11 | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) | 0.016 | ||
| KLF6 | Kruppel-like factor 6 | 0.014 | ||
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.014 | ||
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | 0.014 | ||
| DUSP5 | dual specificity phosphatase 5 | 0.013 | ||
| PLDN | pallidin homolog (mouse) | 0.013 | ||
| ATF2 | activating transcription factor 2 | 0.013 | ||
| NAF1 | nuclear assembly factor 1 homolog (S. cerevisiae) | 0.012 | ||
| MS4A7 | membrane-spanning 4-domains, subfamily A, member 7 | 0.012 | ||
| MAGEH1 | melanoma antigen family H, 1 | 0.012 | ||
| ACAT1 | acetyl-CoA acetyltransferase 1 | 0.012 | ||
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.012 | ||
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.012 | ||
| CDK10 | cyclin-dependent kinase 10 | 0.011 | ||
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.011 | ||
| BCL2L2 | BCL2-like 2 | 0.011 | ||
| IER5 | immediate early response 5 | 0.011 | ||
| CSRNP1 | cysteine-serine-rich nuclear protein 1 | 0.010 |