IMP
Process View
The network for 'regulation of interferon alpha production' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
regulation of interferon alpha production
Any process that modulates the frequency, rate, or extent of interferon-alpha production.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 | 0.948 | |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.905 | |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.884 | |
| MYD88 | myeloid differentiation primary response gene (88) | 0.868 | |
| STAT2 | signal transducer and activator of transcription 2, 113kDa | 0.823 | |
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta | 0.626 | |
| TBK1 | TANK-binding kinase 1 | 0.558 | |
| IRF7 | interferon regulatory factor 7 | 0.518 | |
| IRF3 | interferon regulatory factor 3 | 0.470 | |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 0.300 | |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.218 | |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.210 | |
| TIRAP | toll-interleukin 1 receptor (TIR) domain containing adaptor protein | 0.191 | |
| IRF1 | interferon regulatory factor 1 | 0.171 | |
| IRAK1 | interleukin-1 receptor-associated kinase 1 | 0.164 | |
| TRIM21 | tripartite motif containing 21 | 0.161 | |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 | 0.138 | |
| IKBKG | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma | 0.133 | |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.099 | |
| NLRC5 | NLR family, CARD domain containing 5 | 0.096 | |
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced | 0.087 | |
| TRIM25 | tripartite motif containing 25 | 0.069 | |
| IRF9 | interferon regulatory factor 9 | 0.067 | |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.057 | |
| CALCOCO2 | calcium binding and coiled-coil domain 2 | 0.043 | |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.041 | |
| AZI2 | 5-azacytidine induced 2 | 0.040 | |
| PRKRA | protein kinase, interferon-inducible double stranded RNA dependent activator | 0.038 | |
| ADAR | adenosine deaminase, RNA-specific | 0.038 | |
| SP110 | SP110 nuclear body protein | 0.037 | |
| IFNAR2 | interferon (alpha, beta and omega) receptor 2 | 0.036 | |
| CREBBP | CREB binding protein | 0.035 | |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta | 0.030 | |
| MAVS | mitochondrial antiviral signaling protein | 0.029 | |
| PPP2R2B | protein phosphatase 2, regulatory subunit B, beta | 0.028 | |
| EIF2C2 | eukaryotic translation initiation factor 2C, 2 | 0.028 | |
| TANK | TRAF family member-associated NFKB activator | 0.027 | |
| PIAS4 | protein inhibitor of activated STAT, 4 | 0.026 | |
| C19orf66 | chromosome 19 open reading frame 66 | 0.026 | |
| IFIH1 | interferon induced with helicase C domain 1 | 0.024 | |
| TLR2 | toll-like receptor 2 | 0.024 | |
| IFI35 | interferon-induced protein 35 | 0.021 | |
| IRF2 | interferon regulatory factor 2 | 0.020 | |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.020 | |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 | 0.018 | |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.018 | |
| TRANK1 | tetratricopeptide repeat and ankyrin repeat containing 1 | 0.018 | |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.017 | |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.017 | |
| KIAA1274 | KIAA1274 | 0.016 | |
| ABL1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.016 | |
| TLR4 | toll-like receptor 4 | 0.015 | |
| TICAM2 | toll-like receptor adaptor molecule 2 | 0.015 | |
| KAT2B | K(lysine) acetyltransferase 2B | 0.014 | |
| NMI | N-myc (and STAT) interactor | 0.014 | |
| PPP3CB | protein phosphatase 3, catalytic subunit, beta isozyme | 0.014 | |
| OPTN | optineurin | 0.014 | |
| IRF8 | interferon regulatory factor 8 | 0.013 | |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.012 | |
| TMEM140 | transmembrane protein 140 | 0.012 | |
| PRKD2 | protein kinase D2 | 0.012 | |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.011 | |
| CLTC | clathrin, heavy chain (Hc) | 0.011 | |
| DTX3L | deltex 3-like (Drosophila) | 0.011 | |
| TRAF2 | TNF receptor-associated factor 2 | 0.011 | |
| MAFB | v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian) | 0.011 | |
| JAK2 | Janus kinase 2 | 0.011 | |
| FKBP5 | FK506 binding protein 5 | 0.011 | |
| TLR1 | toll-like receptor 1 | 0.010 | |
| EIF2C1 | eukaryotic translation initiation factor 2C, 1 | 0.010 |
Loading network...
Mus musculus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Gbp7 | guanylate binding protein 7 | 0.972 | |
| Gbp2 | guanylate binding protein 2 | 0.968 | |
| Irgm1 | immunity-related GTPase family M member 1 | 0.952 | |
| Gbp3 | guanylate binding protein 3 | 0.930 | |
| Iigp1 | interferon inducible GTPase 1 | 0.920 | |
| Igtp | interferon gamma induced GTPase | 0.891 | |
| Casp4 | caspase 4, apoptosis-related cysteine peptidase | 0.881 | |
| Irgm2 | immunity-related GTPase family M member 2 | 0.851 | |
| Ifih1 | interferon induced with helicase C domain 1 | 0.840 | |
| Casp1 | caspase 1 | 0.817 | |
| Stat1 | signal transducer and activator of transcription 1 | 0.779 | |
| Ifit1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.624 | |
| Tgtp2 | T-cell specific GTPase 2 | 0.616 | |
| Ifi47 | interferon gamma inducible protein 47 | 0.444 | |
| Trim21 | tripartite motif-containing 21 | 0.435 | |
| Ifit2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.305 | |
| Aim2 | absent in melanoma 2 | 0.295 | |
| Usp18 | ubiquitin specific peptidase 18 | 0.287 | |
| Irf9 | interferon regulatory factor 9 | 0.282 | |
| Trim30a | tripartite motif-containing 30A | 0.267 | |
| Ddx60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.215 | |
| Ifit3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.200 | |
| Parp14 | poly (ADP-ribose) polymerase family, member 14 | 0.193 | |
| Myd88 | myeloid differentiation primary response gene 88 | 0.180 | |
| Rtp4 | receptor transporter protein 4 | 0.171 | |
| Tlr4 | toll-like receptor 4 | 0.165 | |
| Psmb8 | proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7) | 0.123 | |
| Gbp6 | guanylate binding protein 6 | 0.123 | |
| Ccr2 | chemokine (C-C motif) receptor 2 | 0.117 | |
| Pycard | PYD and CARD domain containing | 0.095 | |
| Ticam1 | toll-like receptor adaptor molecule 1 | 0.085 | |
| Oasl2 | 2'-5' oligoadenylate synthetase-like 2 | 0.083 | |
| Cxcl10 | chemokine (C-X-C motif) ligand 10 | 0.081 | |
| Rsad2 | radical S-adenosyl methionine domain containing 2 | 0.072 | |
| Serpinb9 | serine (or cysteine) peptidase inhibitor, clade B, member 9 | 0.070 | |
| Parp9 | poly (ADP-ribose) polymerase family, member 9 | 0.056 | |
| Nmi | N-myc (and STAT) interactor | 0.055 | |
| Irf8 | interferon regulatory factor 8 | 0.048 | |
| Ifi44 | interferon-induced protein 44 | 0.047 | |
| Gbp10 | guanylate-binding protein 10 | 0.047 | |
| Samd9l | sterile alpha motif domain containing 9-like | 0.045 | |
| Uba7 | ubiquitin-like modifier activating enzyme 7 | 0.045 | |
| H2-Q7 | histocompatibility 2, Q region locus 7 | 0.040 | |
| Unc93b1 | unc-93 homolog B1 (C. elegans) | 0.036 | |
| Sfpi1 | SFFV proviral integration 1 | 0.036 | |
| Casp12 | caspase 12 | 0.036 | |
| Cd180 | CD180 antigen | 0.032 | |
| AW112010 | expressed sequence AW112010 | 0.029 | |
| Trim25 | tripartite motif-containing 25 | 0.028 | |
| Map3k8 | mitogen-activated protein kinase kinase kinase 8 | 0.028 | |
| D14Ertd668e | DNA segment, Chr 14, ERATO Doi 668, expressed | 0.027 | |
| Irf7 | interferon regulatory factor 7 | 0.025 | |
| Il10 | interleukin 10 | 0.025 | |
| Erap1 | endoplasmic reticulum aminopeptidase 1 | 0.024 | |
| Parp12 | poly (ADP-ribose) polymerase family, member 12 | 0.023 | |
| Ms4a4c | membrane-spanning 4-domains, subfamily A, member 4C | 0.023 | |
| Trim30d | tripartite motif-containing 30D | 0.022 | |
| Nlrp3 | NLR family, pyrin domain containing 3 | 0.022 | |
| Tnfrsf1b | tumor necrosis factor receptor superfamily, member 1b | 0.021 | |
| Irf1 | interferon regulatory factor 1 | 0.021 | |
| Birc3 | baculoviral IAP repeat-containing 3 | 0.020 | |
| Samhd1 | SAM domain and HD domain, 1 | 0.020 | |
| Nfkb1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 | 0.020 | |
| BC006779 | cDNA sequence BC006779 | 0.019 | |
| Herc6 | hect domain and RLD 6 | 0.019 | |
| Psmb9 | proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2) | 0.017 | |
| Ms4a6b | membrane-spanning 4-domains, subfamily A, member 6B | 0.015 | |
| Ifi203 | interferon activated gene 203 | 0.015 | |
| Lyz2 | lysozyme 2 | 0.015 | |
| Csf1 | colony stimulating factor 1 (macrophage) | 0.015 | |
| Dtx3l | deltex 3-like (Drosophila) | 0.014 | |
| Cd274 | CD274 antigen | 0.014 | |
| Cd14 | CD14 antigen | 0.014 | |
| Ikzf1 | IKAROS family zinc finger 1 | 0.013 | |
| Ifi35 | interferon-induced protein 35 | 0.013 | |
| Hspa9 | heat shock protein 9 | 0.013 | |
| 1810019J16Rik | RIKEN cDNA 1810019J16 gene | 0.012 | |
| Ccl2 | chemokine (C-C motif) ligand 2 | 0.012 | |
| Cmpk2 | cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial | 0.012 | |
| Isg15 | ISG15 ubiquitin-like modifier | 0.012 | |
| Cxcl9 | chemokine (C-X-C motif) ligand 9 | 0.011 | |
| Tank | TRAF family member-associated Nf-kappa B activator | 0.010 | |
| Tnf | tumor necrosis factor | 0.010 |