IMP

Process View

Homo sapiens

11 genes annotated in human

regulation of circadian rhythm

Any process that modulates the frequency, rate or extent of a circadian rhythm. A circadian rhythm is a biological process in an organism that recurs with a regularity of approximately 24 hours.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of circadian rhythm"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of circadian rhythm" (in gray)

Name	Description	Probability	Func Analog Organism
DLG4	discs, large homolog 4 (Drosophila)	0.742
PTBP1	polypyrimidine tract binding protein 1	0.731
KDM1A	lysine (K)-specific demethylase 1A	0.627
SFPQ	splicing factor proline/glutamine-rich	0.455	Mouse
ADORA2A	adenosine A2a receptor	0.441	Rat
ACTN2	actinin, alpha 2	0.408
PRKAB1	protein kinase, AMP-activated, beta 1 non-catalytic subunit	0.272
HNF4A	hepatocyte nuclear factor 4, alpha	0.236
BTRC	beta-transducin repeat containing	0.231
DRD2	dopamine receptor D2	0.222	Rat
SIRT1	sirtuin 1	0.212
NR0B1	nuclear receptor subfamily 0, group B, member 1	0.144
NCL	nucleolin	0.127
CLOCK	clock homolog (mouse)	0.125	Rat Fly
PRKAB2	protein kinase, AMP-activated, beta 2 non-catalytic subunit	0.121
HNRNPD	heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)	0.110
RB1	retinoblastoma 1	0.109
HNRNPA2B1	heterogeneous nuclear ribonucleoprotein A2/B1	0.106
ACACA	acetyl-CoA carboxylase alpha	0.100
EED	embryonic ectoderm development	0.091
ARNTL	aryl hydrocarbon receptor nuclear translocator-like	0.082	Mouse Fly
BHLHE40	basic helix-loop-helix family, member e40	0.075	Mouse Rat
KCNA4	potassium voltage-gated channel, shaker-related subfamily, member 4	0.071	Fly
IGF1R	insulin-like growth factor 1 receptor	0.068	Fly
PPP1R9B	protein phosphatase 1, regulatory (inhibitor) subunit 9B	0.066
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.060
PHF19	PHD finger protein 19	0.053
EZH2	enhancer of zeste homolog 2 (Drosophila)	0.052
NAMPT	nicotinamide phosphoribosyltransferase	0.050
FBXW11	F-box and WD repeat domain containing 11	0.050	Human Mouse
CPE	carboxypeptidase E	0.049
IRS1	insulin receptor substrate 1	0.048
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.048	Mouse
KCNA1	potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)	0.047	Fly
HIPK2	homeodomain interacting protein kinase 2	0.047
NCOR2	nuclear receptor corepressor 2	0.045
AXIN1	axin 1	0.044
EWSR1	Ewing sarcoma breakpoint region 1	0.042
CSNK1E	casein kinase 1, epsilon	0.039	Mouse Fly
EP300	E1A binding protein p300	0.038
INSR	insulin receptor	0.038	Fly
DNMT3B	DNA (cytosine-5-)-methyltransferase 3 beta	0.036
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.035
GRIN2B	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	0.035
PJA1	praja ring finger 1	0.034
AKAP11	A kinase (PRKA) anchor protein 11	0.033
NFIL3	nuclear factor, interleukin 3 regulated	0.033
CSNK2A1	casein kinase 2, alpha 1 polypeptide	0.031
HNRNPA0	heterogeneous nuclear ribonucleoprotein A0	0.031
DVL3	dishevelled, dsh homolog 3 (Drosophila)	0.028
HNRNPA3	heterogeneous nuclear ribonucleoprotein A3	0.028
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.028
IRS2	insulin receptor substrate 2	0.028
CDCA4	cell division cycle associated 4	0.026
PIN1	peptidylprolyl cis/trans isomerase, NIMA-interacting 1	0.026
CHEK2	CHK2 checkpoint homolog (S. pombe)	0.025
SMAD2	SMAD family member 2	0.025
CHEK1	CHK1 checkpoint homolog (S. pombe)	0.025
ESRRG	estrogen-related receptor gamma	0.025
PPARG	peroxisome proliferator-activated receptor gamma	0.024
FUS	fused in sarcoma	0.024
SETD7	SET domain containing (lysine methyltransferase) 7	0.024
GRB10	growth factor receptor-bound protein 10	0.023
HIVEP1	human immunodeficiency virus type I enhancer binding protein 1	0.023
HNRNPH3	heterogeneous nuclear ribonucleoprotein H3 (2H9)	0.022
GRIN2C	glutamate receptor, ionotropic, N-methyl D-aspartate 2C	0.022
GRIN2A	glutamate receptor, ionotropic, N-methyl D-aspartate 2A	0.022
SUZ12	suppressor of zeste 12 homolog (Drosophila)	0.021
HNRNPA1	heterogeneous nuclear ribonucleoprotein A1	0.021
AKIP1	A kinase (PRKA) interacting protein 1	0.020
PPP1R2	protein phosphatase 1, regulatory (inhibitor) subunit 2	0.019
OCLN	occludin	0.019
SP100	SP100 nuclear antigen	0.018
SMAD3	SMAD family member 3	0.018
HMGA1	high mobility group AT-hook 1	0.017
NR0B2	nuclear receptor subfamily 0, group B, member 2	0.017
RPS6KA5	ribosomal protein S6 kinase, 90kDa, polypeptide 5	0.017
CREBBP	CREB binding protein	0.017
KLF10	Kruppel-like factor 10	0.017	Rat
MAFF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)	0.017
SP1	Sp1 transcription factor	0.016
RYR2	ryanodine receptor 2 (cardiac)	0.016
WBP4	WW domain binding protein 4 (formin binding protein 21)	0.015
PRKACA	protein kinase, cAMP-dependent, catalytic, alpha	0.015	Fly
ZMYM2	zinc finger, MYM-type 2	0.014
ADORA1	adenosine A1 receptor	0.013	Rat
TOP1	topoisomerase (DNA) I	0.013
SRSF2	serine/arginine-rich splicing factor 2	0.013
BAZ1B	bromodomain adjacent to zinc finger domain, 1B	0.013
ERBB4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.013
DNAJA1	DnaJ (Hsp40) homolog, subfamily A, member 1	0.013
GATAD2A	GATA zinc finger domain containing 2A	0.012
PRKAR1A	protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)	0.012
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.012
NCOR1	nuclear receptor corepressor 1	0.012
USP46	ubiquitin specific peptidase 46	0.012
NR4A2	nuclear receptor subfamily 4, group A, member 2	0.012
NR5A2	nuclear receptor subfamily 5, group A, member 2	0.012
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.012
PAX8	paired box 8	0.012
MYOZ1	myozenin 1	0.012
SMAD7	SMAD family member 7	0.012
DLGAP1	discs, large (Drosophila) homolog-associated protein 1	0.012
VEGFA	vascular endothelial growth factor A	0.011
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.011
RBBP4	retinoblastoma binding protein 4	0.011
CPSF6	cleavage and polyadenylation specific factor 6, 68kDa	0.011
SUV39H1	suppressor of variegation 3-9 homolog 1 (Drosophila)	0.011	Mouse
NCOA1	nuclear receptor coactivator 1	0.011
C5orf41	chromosome 5 open reading frame 41	0.011
FBXO33	F-box protein 33	0.011
SLC6A3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.011
HNRNPF	heterogeneous nuclear ribonucleoprotein F	0.010