IMP

Process View

Homo sapiens

9 genes annotated in human

response to thyroid hormone

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroid hormone stimulus.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in human Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "response to thyroid hormone"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "response to thyroid hormone" (in gray)

Name	Description	Probability	Func Analog Organism
TAL1	T-cell acute lymphocytic leukemia 1	0.996
HNF4A	hepatocyte nuclear factor 4, alpha	0.697
NPC2	Niemann-Pick disease, type C2	0.635
PSAP	prosaposin	0.578
LDB1	LIM domain binding 1	0.393
ESRRG	estrogen-related receptor gamma	0.321
PRDX1	peroxiredoxin 1	0.305
CTSB	cathepsin B	0.270
PPARG	peroxisome proliferator-activated receptor gamma	0.268
FTL	ferritin, light polypeptide	0.229
CD63	CD63 molecule	0.215
HEXB	hexosaminidase B (beta polypeptide)	0.159
RGS2	regulator of G-protein signaling 2, 24kDa	0.150
CSTA	cystatin A (stefin A)	0.138
MED10	mediator complex subunit 10	0.102
INCENP	inner centromere protein antigens 135/155kDa	0.094
COL1A1	collagen, type I, alpha 1	0.085
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.082
B2M	beta-2-microglobulin	0.082
COL3A1	collagen, type III, alpha 1	0.076
GATA2	GATA binding protein 2	0.075	Human
STAT1	signal transducer and activator of transcription 1, 91kDa	0.071
TBX5	T-box 5	0.061
KITLG	KIT ligand	0.060
IFI30	interferon, gamma-inducible protein 30	0.052
CTSL1	cathepsin L1	0.052
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.052
DYNLT1	dynein, light chain, Tctex-type 1	0.052
NFE2L2	nuclear factor (erythroid-derived 2)-like 2	0.050
MED29	mediator complex subunit 29	0.046
ANXA2	annexin A2	0.043
LAMP1	lysosomal-associated membrane protein 1	0.042
HLA-B	major histocompatibility complex, class I, B	0.041
GPNMB	glycoprotein (transmembrane) nmb	0.041
SEC24D	SEC24 family, member D (S. cerevisiae)	0.039
FTH1	ferritin, heavy polypeptide 1	0.038
TIMP1	TIMP metallopeptidase inhibitor 1	0.037
SAT1	spermidine/spermine N1-acetyltransferase 1	0.037
TPP1	tripeptidyl peptidase I	0.035
S100A4	S100 calcium binding protein A4	0.032
CDK19	cyclin-dependent kinase 19	0.031
S100A10	S100 calcium binding protein A10	0.031
AMBP	alpha-1-microglobulin/bikunin precursor	0.031
MED14	mediator complex subunit 14	0.030
RUNX1	runt-related transcription factor 1	0.030
AURKB	aurora kinase B	0.028
ASAH1	N-acylsphingosine amidohydrolase (acid ceramidase) 1	0.028
ZFPM1	zinc finger protein, multitype 1	0.027
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.025
NFE2L1	nuclear factor (erythroid-derived 2)-like 1	0.024
LGMN	legumain	0.023
GSTO1	glutathione S-transferase omega 1	0.023
CTSD	cathepsin D	0.023
CSTB	cystatin B (stefin B)	0.023
LDB2	LIM domain binding 2	0.022
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.021
IFNGR1	interferon gamma receptor 1	0.020
IL10RB	interleukin 10 receptor, beta	0.020
TGS1	trimethylguanosine synthase 1	0.020
CDK8	cyclin-dependent kinase 8	0.018
NR0B2	nuclear receptor subfamily 0, group B, member 2	0.018
ANXA5	annexin A5	0.018
DAZAP2	DAZ associated protein 2	0.018
CTSA	cathepsin A	0.018
RXRA	retinoid X receptor, alpha	0.018
MLLT4	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4	0.018
LMO2	LIM domain only 2 (rhombotin-like 1)	0.018
MAPRE2	microtubule-associated protein, RP/EB family, member 2	0.017
GRN	granulin	0.017
SDCBP	syndecan binding protein (syntenin)	0.016
MED13	mediator complex subunit 13	0.016
TCF21	transcription factor 21	0.016
LOX	lysyl oxidase	0.016
GNS	glucosamine (N-acetyl)-6-sulfatase	0.015
LY96	lymphocyte antigen 96	0.014
HLA-C	major histocompatibility complex, class I, C	0.014
SOD2	superoxide dismutase 2, mitochondrial	0.014
CASP1	caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)	0.014
SQRDL	sulfide quinone reductase-like (yeast)	0.013
SOCS1	suppressor of cytokine signaling 1	0.012
CTSH	cathepsin H	0.012
DPP3	dipeptidyl-peptidase 3	0.012
HLA-A	major histocompatibility complex, class I, A	0.012
LGALS3	lectin, galactoside-binding, soluble, 3	0.011
CREG1	cellular repressor of E1A-stimulated genes 1	0.011
S100A6	S100 calcium binding protein A6	0.011
TGFBI	transforming growth factor, beta-induced, 68kDa	0.011
THRA	thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)	0.011
ITGA2B	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)	0.011
TSC22D3	TSC22 domain family, member 3	0.011
GATA4	GATA binding protein 4	0.011	Human
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.011
KYNU	kynureninase	0.011
KLF13	Kruppel-like factor 13	0.011	Human
HMOX1	heme oxygenase (decycling) 1	0.011
PRDX4	peroxiredoxin 4	0.011
GAPDH	glyceraldehyde-3-phosphate dehydrogenase	0.011
KIF20A	kinesin family member 20A	0.010
TMSB4X	thymosin beta 4, X-linked	0.010
MAFG	v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)	0.010
GATA1	GATA binding protein 1 (globin transcription factor 1)	0.010