IMP

Process View

Homo sapiens

18 genes annotated in human

Multi-species View

endothelial cell development

GO:0001885

The progression of an endothelial cell over time, from its formation to the mature structure.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "endothelial cell development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "endothelial cell development" (in gray)

Name	Description	Probability	Func Analog Organism
CAB39	calcium binding protein 39	0.725
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.597
DTNA	dystrobrevin, alpha	0.416
ABI1	abl-interactor 1	0.291
CD44	CD44 molecule (Indian blood group)	0.269
EZR	ezrin	0.229
LAT	linker for activation of T cells	0.220
PAX3	paired box 3	0.206
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.200
SCHIP1	schwannomin interacting protein 1	0.179
PBX1	pre-B-cell leukemia homeobox 1	0.161
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.140
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.137
GAS6	growth arrest-specific 6	0.132
ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha	0.121
POU5F1	POU class 5 homeobox 1	0.114
PTPN13	protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)	0.102
GNB1	guanine nucleotide binding protein (G protein), beta polypeptide 1	0.092
CFTR	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	0.088
MSN	moesin	0.087
RAP1A	RAP1A, member of RAS oncogene family	0.084
CAV1	caveolin 1, caveolae protein, 22kDa	0.071
TECPR1	tectonin beta-propeller repeat containing 1	0.063
ACTR3	ARP3 actin-related protein 3 homolog (yeast)	0.063
POU3F2	POU class 3 homeobox 2	0.062
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.060
SMAD7	SMAD family member 7	0.058
ID3	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein	0.058
RANBP9	RAN binding protein 9	0.045
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.044
HGF	hepatocyte growth factor (hepapoietin A; scatter factor)	0.043
DAG1	dystroglycan 1 (dystrophin-associated glycoprotein 1)	0.042
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.041
GAB1	GRB2-associated binding protein 1	0.041
TJP1	tight junction protein 1 (zona occludens 1)	0.036
RAP1B	RAP1B, member of RAS oncogene family	0.036
TBC1D10A	TBC1 domain family, member 10A	0.033
FGFR1	fibroblast growth factor receptor 1	0.032
GJA1	gap junction protein, alpha 1, 43kDa	0.031
IRAK1	interleukin-1 receptor-associated kinase 1	0.031
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.030
PTPN11	protein tyrosine phosphatase, non-receptor type 11	0.029
FLNA	filamin A, alpha	0.029
CXCR5	chemokine (C-X-C motif) receptor 5	0.028
IRAK2	interleukin-1 receptor-associated kinase 2	0.027
TSC22D1	TSC22 domain family, member 1	0.027
BCR	breakpoint cluster region	0.026
IRAK3	interleukin-1 receptor-associated kinase 3	0.025
BZW1	basic leucine zipper and W2 domains 1	0.025
ARHGEF40	Rho guanine nucleotide exchange factor (GEF) 40	0.024
TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.023
MEIS2	Meis homeobox 2	0.022
RHOA	ras homolog gene family, member A	0.022
ADRB2	adrenergic, beta-2-, receptor, surface	0.022
FERMT2	fermitin family member 2	0.021
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.021
MAP4K1	mitogen-activated protein kinase kinase kinase kinase 1	0.021
CASK	calcium/calmodulin-dependent serine protein kinase (MAGUK family)	0.020
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.019
NRAS	neuroblastoma RAS viral (v-ras) oncogene homolog	0.019
MAP4K5	mitogen-activated protein kinase kinase kinase kinase 5	0.019
MED28	mediator complex subunit 28	0.019
CDV3	CDV3 homolog (mouse)	0.018
SMAD2	SMAD family member 2	0.018
INADL	InaD-like (Drosophila)	0.018
AXL	AXL receptor tyrosine kinase	0.018	Human
EPS8	epidermal growth factor receptor pathway substrate 8	0.017
ATP8	ATP synthase F0 subunit 8	0.017
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.017
HOXA9	homeobox A9	0.017
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.017
RHOG	ras homolog gene family, member G (rho G)	0.017
DTNB	dystrobrevin, beta	0.016
RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2	0.016
TJP2	tight junction protein 2 (zona occludens 2)	0.016
EGFR	epidermal growth factor receptor	0.016
CSNK1E	casein kinase 1, epsilon	0.015
CLDN5	claudin 5	0.015
ITSN2	intersectin 2	0.015
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.015
RALGDS	ral guanine nucleotide dissociation stimulator	0.015
RUNDC3A	RUN domain containing 3A	0.014
CDKN1B	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	0.014
TLR4	toll-like receptor 4	0.014
WNK4	WNK lysine deficient protein kinase 4	0.014
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.014
RGS19	regulator of G-protein signaling 19	0.013
ITGAL	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)	0.013
MED13	mediator complex subunit 13	0.013
ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	0.013
PICALM	phosphatidylinositol binding clathrin assembly protein	0.013
ERBB2IP	erbb2 interacting protein	0.012
YES1	v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1	0.012
WIPF1	WAS/WASL interacting protein family, member 1	0.012
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.012
SELPLG	selectin P ligand	0.012
CORO1C	coronin, actin binding protein, 1C	0.012
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.011
DNM1	dynamin 1	0.011
GNA13	guanine nucleotide binding protein (G protein), alpha 13	0.011
STK10	serine/threonine kinase 10	0.011
ARL8B	ADP-ribosylation factor-like 8B	0.011
ADAM11	ADAM metallopeptidase domain 11	0.011
TAB2	TGF-beta activated kinase 1/MAP3K7 binding protein 2	0.011
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.011
PDCD10	programmed cell death 10	0.010
VCAM1	vascular cell adhesion molecule 1	0.010
IRAK4	interleukin-1 receptor-associated kinase 4	0.010
RAMP3	receptor (G protein-coupled) activity modifying protein 3	0.010