IMP

Process View

Homo sapiens

23 genes annotated in human

glutamate receptor signaling pathway

A series of molecular signals initiated by the binding of glutamate to a glutamate receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "glutamate receptor signaling pathway"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "glutamate receptor signaling pathway" (in gray)

Name	Description	Probability	Func Analog Organism
DLG4	discs, large homolog 4 (Drosophila)	1.000	Rat
KCNA1	potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)	1.000
GRIN2B	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	1.000	Human Mouse Rat
DLGAP1	discs, large (Drosophila) homolog-associated protein 1	0.997
GRIN2A	glutamate receptor, ionotropic, N-methyl D-aspartate 2A	0.996	Human Mouse Rat
GRIN2C	glutamate receptor, ionotropic, N-methyl D-aspartate 2C	0.992	Human Mouse Rat
GRIN1	glutamate receptor, ionotropic, N-methyl D-aspartate 1	0.992
KCNA4	potassium voltage-gated channel, shaker-related subfamily, member 4	0.976
ERBB4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.961
NLGN1	neuroligin 1	0.943	Mouse Rat
CAMK2A	calcium/calmodulin-dependent protein kinase II alpha	0.872
SPRR2A	small proline-rich protein 2A	0.672
ARRB1	arrestin, beta 1	0.669
CRIPT	cysteine-rich PDZ-binding protein	0.588
CACNG2	calcium channel, voltage-dependent, gamma subunit 2	0.439	Human Rat
GRIA2	glutamate receptor, ionotropic, AMPA 2	0.393
CRHR1	corticotropin releasing hormone receptor 1	0.385
ESRRG	estrogen-related receptor gamma	0.297
GRIK5	glutamate receptor, ionotropic, kainate 5	0.244
MYO16	myosin XVI	0.242
GRIA1	glutamate receptor, ionotropic, AMPA 1	0.238
PPARG	peroxisome proliferator-activated receptor gamma	0.219
GRIP1	glutamate receptor interacting protein 1	0.191
HNF4A	hepatocyte nuclear factor 4, alpha	0.190
HDAC4	histone deacetylase 4	0.141
MAPK8IP1	mitogen-activated protein kinase 8 interacting protein 1	0.121
MATK	megakaryocyte-associated tyrosine kinase	0.099
BAI2	brain-specific angiogenesis inhibitor 2	0.082
GRIK1	glutamate receptor, ionotropic, kainate 1	0.079
APP	amyloid beta (A4) precursor protein	0.077	Mouse
SSTR2	somatostatin receptor 2	0.074
KCNJ4	potassium inwardly-rectifying channel, subfamily J, member 4	0.068
DLG2	discs, large homolog 2 (Drosophila)	0.062
APBB1	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)	0.060
CRMP1	collapsin response mediator protein 1	0.058
GAD2	glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)	0.055
BAI1	brain-specific angiogenesis inhibitor 1	0.054
GRIK2	glutamate receptor, ionotropic, kainate 2	0.053
HDAC9	histone deacetylase 9	0.053
ADRBK1	adrenergic, beta, receptor kinase 1	0.052
ATP2B2	ATPase, Ca++ transporting, plasma membrane 2	0.051
KIFC2	kinesin family member C2	0.046
GRIN2D	glutamate receptor, ionotropic, N-methyl D-aspartate 2D	0.043	Human Mouse Rat
MED28	mediator complex subunit 28	0.042
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.037
PITPNM1	phosphatidylinositol transfer protein, membrane-associated 1	0.034
KCNQ2	potassium voltage-gated channel, KQT-like subfamily, member 2	0.034
RGS7	regulator of G-protein signaling 7	0.034
NRXN1	neurexin 1	0.034	Mouse
KCNIP2	Kv channel interacting protein 2	0.034
DLGAP2	discs, large (Drosophila) homolog-associated protein 2	0.033
PRKCG	protein kinase C, gamma	0.032
NOS1	nitric oxide synthase 1 (neuronal)	0.031
HTR2C	5-hydroxytryptamine (serotonin) receptor 2C	0.030
PDCD6IP	programmed cell death 6 interacting protein	0.029
SRCIN1	SRC kinase signaling inhibitor 1	0.027
MAP2	microtubule-associated protein 2	0.026
ACHE	acetylcholinesterase	0.025
MAP3K10	mitogen-activated protein kinase kinase kinase 10	0.025
MEF2A	myocyte enhancer factor 2A	0.025
GDAP1L1	ganglioside-induced differentiation-associated protein 1-like 1	0.025
ACTL6B	actin-like 6B	0.024
NLGN3	neuroligin 3	0.024	Mouse
GRIA4	glutamate receptor, ionotrophic, AMPA 4	0.023
KIF5A	kinesin family member 5A	0.022
KCNF1	potassium voltage-gated channel, subfamily F, member 1	0.022
NEUROD2	neurogenic differentiation 2	0.021
CACNA1B	calcium channel, voltage-dependent, N type, alpha 1B subunit	0.021
ANKS1B	ankyrin repeat and sterile alpha motif domain containing 1B	0.021
GPR6	G protein-coupled receptor 6	0.021
GNAO1	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O	0.021
GRID2	glutamate receptor, ionotropic, delta 2	0.021
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.021
NSF	N-ethylmaleimide-sensitive factor	0.020
SLC6A11	solute carrier family 6 (neurotransmitter transporter, GABA), member 11	0.020
SYT13	synaptotagmin XIII	0.020
GRM3	glutamate receptor, metabotropic 3	0.020	Human Rat Fly
DLG3	discs, large homolog 3 (Drosophila)	0.020
SEZ6L	seizure related 6 homolog (mouse)-like	0.020
NOVA2	neuro-oncological ventral antigen 2	0.020
HMP19	HMP19 protein	0.019
ADRB1	adrenergic, beta-1-, receptor	0.019
ZNF784	zinc finger protein 784	0.019
FAM5B	family with sequence similarity 5, member B	0.019
HTR2A	5-hydroxytryptamine (serotonin) receptor 2A	0.019
GRIN3B	glutamate receptor, ionotropic, N-methyl-D-aspartate 3B	0.018	Human Rat
MAG	myelin associated glycoprotein	0.018
PROX1	prospero homeobox 1	0.018
SYT5	synaptotagmin V	0.017
SPTBN1	spectrin, beta, non-erythrocytic 1	0.017
RAI1	retinoic acid induced 1	0.017
GAP43	growth associated protein 43	0.017
SNCB	synuclein, beta	0.016
CACNG3	calcium channel, voltage-dependent, gamma subunit 3	0.016	Human Rat
APBA1	amyloid beta (A4) precursor protein-binding, family A, member 1	0.016
NRXN3	neurexin 3	0.016
CELF3	CUGBP, Elav-like family member 3	0.016
RGS6	regulator of G-protein signaling 6	0.016
GHSR	growth hormone secretagogue receptor	0.016
MAPT	microtubule-associated protein tau	0.016
DLGAP3	discs, large (Drosophila) homolog-associated protein 3	0.016
UNC13A	unc-13 homolog A (C. elegans)	0.015
ATP2B3	ATPase, Ca++ transporting, plasma membrane 3	0.015
CABP1	calcium binding protein 1	0.015
GABRG2	gamma-aminobutyric acid (GABA) A receptor, gamma 2	0.015
TMEM59L	transmembrane protein 59-like	0.015
KCNT1	potassium channel, subfamily T, member 1	0.015
FUT9	fucosyltransferase 9 (alpha (1,3) fucosyltransferase)	0.015
RYR2	ryanodine receptor 2 (cardiac)	0.015
HCN2	hyperpolarization activated cyclic nucleotide-gated potassium channel 2	0.015
FSTL4	follistatin-like 4	0.015
CAMK1G	calcium/calmodulin-dependent protein kinase IG	0.015
KIAA1045	KIAA1045	0.015
PICK1	protein interacting with PRKCA 1	0.015
HOXD12	homeobox D12	0.015
GRIK4	glutamate receptor, ionotropic, kainate 4	0.015	Human
CADM3	cell adhesion molecule 3	0.015
PSD	pleckstrin and Sec7 domain containing	0.015
FGF12	fibroblast growth factor 12	0.015
PEX5L	peroxisomal biogenesis factor 5-like	0.015
GRM8	glutamate receptor, metabotropic 8	0.014
SIPA1L1	signal-induced proliferation-associated 1 like 1	0.014
CACNA1E	calcium channel, voltage-dependent, R type, alpha 1E subunit	0.014
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.014
MYH14	myosin, heavy chain 14, non-muscle	0.014
PITPNM3	PITPNM family member 3	0.014
KCNJ9	potassium inwardly-rectifying channel, subfamily J, member 9	0.014
GRIK3	glutamate receptor, ionotropic, kainate 3	0.014
DRD1	dopamine receptor D1	0.014
MYH10	myosin, heavy chain 10, non-muscle	0.013
PRLHR	prolactin releasing hormone receptor	0.013
CTNNA2	catenin (cadherin-associated protein), alpha 2	0.013
PTPRA	protein tyrosine phosphatase, receptor type, A	0.013
PDE1B	phosphodiesterase 1B, calmodulin-dependent	0.013
GABRD	gamma-aminobutyric acid (GABA) A receptor, delta	0.013
KCNK9	potassium channel, subfamily K, member 9	0.013
GFAP	glial fibrillary acidic protein	0.013
MAPK4	mitogen-activated protein kinase 4	0.013
GABRA5	gamma-aminobutyric acid (GABA) A receptor, alpha 5	0.013
GABRA2	gamma-aminobutyric acid (GABA) A receptor, alpha 2	0.013
PDZD2	PDZ domain containing 2	0.013
CHRNA4	cholinergic receptor, nicotinic, alpha 4	0.012
GABRG3	gamma-aminobutyric acid (GABA) A receptor, gamma 3	0.012
MYT1	myelin transcription factor 1	0.012
CARTPT	CART prepropeptide	0.012
MAP1A	microtubule-associated protein 1A	0.012
OLIG2	oligodendrocyte lineage transcription factor 2	0.012
CA10	carbonic anhydrase X	0.012
PCDHAC1	protocadherin alpha subfamily C, 1	0.012
GABRA6	gamma-aminobutyric acid (GABA) A receptor, alpha 6	0.012
DPF1	D4, zinc and double PHD fingers family 1	0.012
HPCA	hippocalcin	0.012
TRPC3	transient receptor potential cation channel, subfamily C, member 3	0.012
SNAP91	synaptosomal-associated protein, 91kDa homolog (mouse)	0.012
CTNND2	catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)	0.012
PRKCD	protein kinase C, delta	0.012
MYLK2	myosin light chain kinase 2	0.012
SLC7A10	solute carrier family 7, (neutral amino acid transporter, y+ system) member 10	0.012
IL1RAPL1	interleukin 1 receptor accessory protein-like 1	0.012
SNTG1	syntrophin, gamma 1	0.012
SLC17A6	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6	0.012
SOX14	SRY (sex determining region Y)-box 14	0.012
GRIA3	glutamate receptor, ionotrophic, AMPA 3	0.012
SLC32A1	solute carrier family 32 (GABA vesicular transporter), member 1	0.011
DDX25	DEAD (Asp-Glu-Ala-Asp) box polypeptide 25	0.011
NR1I2	nuclear receptor subfamily 1, group I, member 2	0.011
GABRA1	gamma-aminobutyric acid (GABA) A receptor, alpha 1	0.011
GABBR2	gamma-aminobutyric acid (GABA) B receptor, 2	0.011
LRP2	low density lipoprotein receptor-related protein 2	0.011
KCNC2	potassium voltage-gated channel, Shaw-related subfamily, member 2	0.011
PPT1	palmitoyl-protein thioesterase 1	0.011
SHANK2	SH3 and multiple ankyrin repeat domains 2	0.011
KCNA5	potassium voltage-gated channel, shaker-related subfamily, member 5	0.011
CDH12	cadherin 12, type 2 (N-cadherin 2)	0.011
FYN	FYN oncogene related to SRC, FGR, YES	0.011
ACCN1	amiloride-sensitive cation channel 1, neuronal	0.011
UNC5C	unc-5 homolog C (C. elegans)	0.011
MYT1L	myelin transcription factor 1-like	0.011
KCNMA1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1	0.011
MGAT4C	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)	0.011
CPLX2	complexin 2	0.010
OTOF	otoferlin	0.010
GABRB3	gamma-aminobutyric acid (GABA) A receptor, beta 3	0.010
SNCG	synuclein, gamma (breast cancer-specific protein 1)	0.010
HTR5A	5-hydroxytryptamine (serotonin) receptor 5A	0.010
OPRD1	opioid receptor, delta 1	0.010
SYP	synaptophysin	0.010
SV2C	synaptic vesicle glycoprotein 2C	0.010
DPP6	dipeptidyl-peptidase 6	0.010
ADAMTSL2	ADAMTS-like 2	0.010
FEZF2	FEZ family zinc finger 2	0.010
NEUROD1	neurogenic differentiation 1	0.010
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.010
MMD2	monocyte to macrophage differentiation-associated 2	0.010