IMP

Process View

Homo sapiens

8 genes annotated in human

Multi-species View

regulation of t cell mediated cytotoxicity

GO:0001914

Any process that modulates the frequency, rate, or extent of T cell mediated cytotoxicity.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of t cell mediated cytotoxicity"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of t cell mediated cytotoxicity" (in gray)

Name	Description	Probability	Func Analog Organism
B2M	beta-2-microglobulin	0.998	Mouse
HLA-G	major histocompatibility complex, class I, G	0.995	Human
HLA-A	major histocompatibility complex, class I, A	0.963
HLA-C	major histocompatibility complex, class I, C	0.961	Human
HLA-B	major histocompatibility complex, class I, B	0.924
HLA-E	major histocompatibility complex, class I, E	0.821	Human
MLLT4	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4	0.798
LILRB1	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1	0.729
HLA-F	major histocompatibility complex, class I, F	0.646	Human
TAP1	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)	0.632
LILRA6	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6	0.610
LILRB2	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2	0.549	Human
CCL4	chemokine (C-C motif) ligand 4	0.325	Human
LILRB3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	0.297	Human
CCR5	chemokine (C-C motif) receptor 5	0.273
IL12B	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)	0.269
CCL5	chemokine (C-C motif) ligand 5	0.156	Human
TAPBP	TAP binding protein (tapasin)	0.136
PILRA	paired immunoglobin-like type 2 receptor alpha	0.102
PVRL3	poliovirus receptor-related 3	0.092	Human
CCR1	chemokine (C-C motif) receptor 1	0.074
CXCL9	chemokine (C-X-C motif) ligand 9	0.066
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.058	Human
CXCL2	chemokine (C-X-C motif) ligand 2	0.050
PVRL1	poliovirus receptor-related 1 (herpesvirus entry mediator C)	0.046	Human
IL1B	interleukin 1, beta	0.040
SIGLEC7	sialic acid binding Ig-like lectin 7	0.040
HK3	hexokinase 3 (white cell)	0.039
CCL8	chemokine (C-C motif) ligand 8	0.038	Human
CCL2	chemokine (C-C motif) ligand 2	0.030	Human
IL2RG	interleukin 2 receptor, gamma	0.028
CD163	CD163 molecule	0.023
CCL22	chemokine (C-C motif) ligand 22	0.022	Human
CCL13	chemokine (C-C motif) ligand 13	0.022	Human
LILRA1	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1	0.021	Human
ICAM1	intercellular adhesion molecule 1	0.017
CCL7	chemokine (C-C motif) ligand 7	0.017	Human
IFNG	interferon, gamma	0.017
LILRA2	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2	0.015
CASP8	caspase 8, apoptosis-related cysteine peptidase	0.015
PTAFR	platelet-activating factor receptor	0.014
IDE	insulin-degrading enzyme	0.014
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.013
IL10	interleukin 10	0.013
DPP4	dipeptidyl-peptidase 4	0.013
CCR7	chemokine (C-C motif) receptor 7	0.012
TREM1	triggering receptor expressed on myeloid cells 1	0.012
TJP1	tight junction protein 1 (zona occludens 1)	0.012
NLRP3	NLR family, pyrin domain containing 3	0.011
C1QA	complement component 1, q subcomponent, A chain	0.011
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.011
ABCA1	ATP-binding cassette, sub-family A (ABC1), member 1	0.011
CCL11	chemokine (C-C motif) ligand 11	0.010	Human
FPR3	formyl peptide receptor 3	0.010