IMP

Process View

Homo sapiens

17 genes annotated in human

Multi-species View

vesicle fusion

GO:0006906

Fusion of the membrane of a transport vesicle with its target membrane.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "vesicle fusion"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "vesicle fusion" (in gray)

Name	Description	Probability	Func Analog Organism
SNAP23	synaptosomal-associated protein, 23kDa	0.999	Yeast Fly
NAPA	N-ethylmaleimide-sensitive factor attachment protein, alpha	0.991	Yeast
RAB5A	RAB5A, member RAS oncogene family	0.981	Fly
VAMP3	vesicle-associated membrane protein 3 (cellubrevin)	0.949	Human Mouse
ANXA1	annexin A1	0.918
NSF	N-ethylmaleimide-sensitive factor	0.894	Yeast Fly
SNX6	sorting nexin 6	0.894
SNAP25	synaptosomal-associated protein, 25kDa	0.822	Yeast Fly
MON1B	MON1 homolog B (yeast)	0.738
OCRL	oculocerebrorenal syndrome of Lowe	0.737
VTI1B	vesicle transport through interaction with t-SNAREs homolog 1B (yeast)	0.692
OBSCN	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF	0.656
STX5	syntaxin 5	0.600	Yeast Rat
STX12	syntaxin 12	0.557
STX7	syntaxin 7	0.541	Rat
ITSN1	intersectin 1 (SH3 domain protein)	0.533
STX4	syntaxin 4	0.463	Yeast Mouse
VAMP4	vesicle-associated membrane protein 4	0.443
GDI2	GDP dissociation inhibitor 2	0.436
CAV1	caveolin 1, caveolae protein, 22kDa	0.390	Human
VPS33B	vacuolar protein sorting 33 homolog B (yeast)	0.389
RAB1A	RAB1A, member RAS oncogene family	0.361
GABBR1	gamma-aminobutyric acid (GABA) B receptor, 1	0.352
VAMP8	vesicle-associated membrane protein 8 (endobrevin)	0.350	Mouse
S100A10	S100 calcium binding protein A10	0.324
STX6	syntaxin 6	0.248
SCFD1	sec1 family domain containing 1	0.205	Yeast
USO1	USO1 vesicle docking protein homolog (yeast)	0.178
RABEP1	rabaptin, RAB GTPase binding effector protein 1	0.149
RAB22A	RAB22A, member RAS oncogene family	0.137
STX11	syntaxin 11	0.109	Yeast
CAV2	caveolin 2	0.107
GOLGA2	golgin A2	0.105
SH2D1B	SH2 domain containing 1B	0.098
SEC22B	SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)	0.097
ATF2	activating transcription factor 2	0.085
PICALM	phosphatidylinositol binding clathrin assembly protein	0.081
STX1A	syntaxin 1A (brain)	0.078	Yeast Fly
AP1G1	adaptor-related protein complex 1, gamma 1 subunit	0.069
EXOC4	exocyst complex component 4	0.066
AMPH	amphiphysin	0.064
ADAM15	ADAM metallopeptidase domain 15	0.062
ANXA5	annexin A5	0.061	Human
RAB11FIP1	RAB11 family interacting protein 1 (class I)	0.059
SPTB	spectrin, beta, erythrocytic	0.058
SNX33	sorting nexin 33	0.057
STX8	syntaxin 8	0.052	Yeast Rat
RAB8A	RAB8A, member RAS oncogene family	0.049
RAB11A	RAB11A, member RAS oncogene family	0.047	Fly
RAB10	RAB10, member RAS oncogene family	0.046	Human Yeast
VPS41	vacuolar protein sorting 41 homolog (S. cerevisiae)	0.045
ANKRD27	ankyrin repeat domain 27 (VPS9 domain)	0.043
DNM2	dynamin 2	0.042
RABIF	RAB interacting factor	0.041
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.038
SH2D1A	SH2 domain containing 1A	0.037
PDE6D	phosphodiesterase 6D, cGMP-specific, rod, delta	0.036
ANXA4	annexin A4	0.035	Human
SCP2	sterol carrier protein 2	0.035
SNX2	sorting nexin 2	0.034	Worm
CD63	CD63 molecule	0.033
SH3BGRL	SH3 domain binding glutamic acid-rich protein like	0.033
SH3KBP1	SH3-domain kinase binding protein 1	0.032
SNX1	sorting nexin 1	0.031	Worm
VAMP2	vesicle-associated membrane protein 2 (synaptobrevin 2)	0.030
CD84	CD84 molecule	0.029
PRKCB	protein kinase C, beta	0.029
ZDHHC17	zinc finger, DHHC-type containing 17	0.028
LGALS1	lectin, galactoside-binding, soluble, 1	0.028
SH3RF1	SH3 domain containing ring finger 1	0.028
SDCBP	syndecan binding protein (syntenin)	0.027
GOLM1	golgi membrane protein 1	0.027
EHD1	EH-domain containing 1	0.026
INPP5D	inositol polyphosphate-5-phosphatase, 145kDa	0.025
ANXA2	annexin A2	0.025
RAB14	RAB14, member RAS oncogene family	0.024	Human
S100A11	S100 calcium binding protein A11	0.024
NCF1	neutrophil cytosolic factor 1	0.024
GNA13	guanine nucleotide binding protein (G protein), alpha 13	0.024
COG4	component of oligomeric golgi complex 4	0.024
OPTN	optineurin	0.023
RAB7A	RAB7A, member RAS oncogene family	0.023
RAB6A	RAB6A, member RAS oncogene family	0.023
CALM1	calmodulin 1 (phosphorylase kinase, delta)	0.022
SNX3	sorting nexin 3	0.022
SS18	synovial sarcoma translocation, chromosome 18	0.022
CFL1	cofilin 1 (non-muscle)	0.021
FNBP1	formin binding protein 1	0.020
ARPC4	actin related protein 2/3 complex, subunit 4, 20kDa	0.020
VPS33A	vacuolar protein sorting 33 homolog A (S. cerevisiae)	0.020
STX3	syntaxin 3	0.020	Yeast
GOSR1	golgi SNAP receptor complex member 1	0.020	Yeast
SMPD1	sphingomyelin phosphodiesterase 1, acid lysosomal	0.018
CAST	calpastatin	0.018
PDCD6	programmed cell death 6	0.017
EMP1	epithelial membrane protein 1	0.017
ATP6V1A	ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A	0.017
PKN3	protein kinase N3	0.016
F2R	coagulation factor II (thrombin) receptor	0.016
LRRK2	leucine-rich repeat kinase 2	0.016
ANXA3	annexin A3	0.015	Human
ROD1	ROD1 regulator of differentiation 1 (S. pombe)	0.015
TMSB10	thymosin beta 10	0.014
C19orf6	chromosome 19 open reading frame 6	0.014
CD59	CD59 molecule, complement regulatory protein	0.014
COG5	component of oligomeric golgi complex 5	0.014
GRB7	growth factor receptor-bound protein 7	0.013
RAB1B	RAB1B, member RAS oncogene family	0.013
PRRT2	proline-rich transmembrane protein 2	0.013
CAPG	capping protein (actin filament), gelsolin-like	0.012
SYT1	synaptotagmin I	0.012	Rat Fly
SRPR	signal recognition particle receptor (docking protein)	0.012
CPLX1	complexin 1	0.012
CYBA	cytochrome b-245, alpha polypeptide	0.012
PEX2	peroxisomal biogenesis factor 2	0.012
CALCOCO1	calcium binding and coiled-coil domain 1	0.012
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.012
ARRB2	arrestin, beta 2	0.012
TNIP1	TNFAIP3 interacting protein 1	0.012
RALA	v-ral simian leukemia viral oncogene homolog A (ras related)	0.012
EEA1	early endosome antigen 1	0.011
EMP3	epithelial membrane protein 3	0.011
AHNAK	AHNAK nucleoprotein	0.011
RAB2A	RAB2A, member RAS oncogene family	0.011	Human
GABBR2	gamma-aminobutyric acid (GABA) B receptor, 2	0.011	Fly
FUNDC2	FUN14 domain containing 2	0.011
CLPTM1	cleft lip and palate associated transmembrane protein 1	0.011
S100A6	S100 calcium binding protein A6	0.011
GDE1	glycerophosphodiester phosphodiesterase 1	0.011
ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	0.010
UBA3	ubiquitin-like modifier activating enzyme 3	0.010
MYL12B	myosin, light chain 12B, regulatory	0.010
EIF1B	eukaryotic translation initiation factor 1B	0.010
SYPL1	synaptophysin-like 1	0.010
SH3GL2	SH3-domain GRB2-like 2	0.010
AP1S1	adaptor-related protein complex 1, sigma 1 subunit	0.010
DNM1	dynamin 1	0.010