IMP
Process View
negative regulation of t helper 1 cell activation
Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 1 cell activation.
Loading network...
In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of t helper 1 cell activation"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| CCR5 | chemokine (C-C motif) receptor 5 | 1.000 | ||
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.999 | ||
| CCL4 | chemokine (C-C motif) ligand 4 | 0.998 | Human | |
| CCL13 | chemokine (C-C motif) ligand 13 | 0.968 | Human | |
| CCL2 | chemokine (C-C motif) ligand 2 | 0.964 | Human | |
| IL8 | interleukin 8 | 0.924 | ||
| CCL22 | chemokine (C-C motif) ligand 22 | 0.920 | Human | |
| DPP4 | dipeptidyl-peptidase 4 | 0.915 | ||
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.871 | ||
| CCL8 | chemokine (C-C motif) ligand 8 | 0.865 | Human | |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.843 | Human | |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.806 | ||
| IDE | insulin-degrading enzyme | 0.760 | ||
| CXCL11 | chemokine (C-X-C motif) ligand 11 | 0.716 | ||
| CCR7 | chemokine (C-C motif) receptor 7 | 0.695 | ||
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.677 | ||
| CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) | 0.661 | Human | |
| IL6 | interleukin 6 (interferon, beta 2) | 0.580 | ||
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.569 | ||
| CCL20 | chemokine (C-C motif) ligand 20 | 0.546 | Human | |
| IL1B | interleukin 1, beta | 0.439 | ||
| CCL7 | chemokine (C-C motif) ligand 7 | 0.418 | Human | |
| TNFRSF9 | tumor necrosis factor receptor superfamily, member 9 | 0.408 | ||
| CCL3 | chemokine (C-C motif) ligand 3 | 0.371 | Human | |
| IL7R | interleukin 7 receptor | 0.360 | ||
| IFNG | interferon, gamma | 0.359 | ||
| IL2RB | interleukin 2 receptor, beta | 0.336 | ||
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.331 | ||
| CD83 | CD83 molecule | 0.304 | ||
| TNF | tumor necrosis factor | 0.302 | ||
| CXCR6 | chemokine (C-X-C motif) receptor 6 | 0.292 | ||
| RGS1 | regulator of G-protein signaling 1 | 0.281 | ||
| UBD | ubiquitin D | 0.272 | ||
| CCR4 | chemokine (C-C motif) receptor 4 | 0.263 | ||
| PRF1 | perforin 1 (pore forming protein) | 0.223 | ||
| IL10 | interleukin 10 | 0.205 | ||
| ICAM1 | intercellular adhesion molecule 1 | 0.193 | ||
| SELE | selectin E | 0.181 | ||
| VCAM1 | vascular cell adhesion molecule 1 | 0.168 | ||
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | 0.156 | ||
| MMP12 | matrix metallopeptidase 12 (macrophage elastase) | 0.150 | ||
| GNLY | granulysin | 0.126 | ||
| SIGLEC1 | sialic acid binding Ig-like lectin 1, sialoadhesin | 0.124 | ||
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.116 | ||
| IDO1 | indoleamine 2,3-dioxygenase 1 | 0.115 | ||
| CCR3 | chemokine (C-C motif) receptor 3 | 0.111 | ||
| CCL19 | chemokine (C-C motif) ligand 19 | 0.107 | Human | |
| ARRB1 | arrestin, beta 1 | 0.094 | ||
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | 0.093 | ||
| FPR3 | formyl peptide receptor 3 | 0.082 | ||
| TRAF1 | TNF receptor-associated factor 1 | 0.081 | ||
| CCR1 | chemokine (C-C motif) receptor 1 | 0.079 | ||
| KLRD1 | killer cell lectin-like receptor subfamily D, member 1 | 0.070 | ||
| CH25H | cholesterol 25-hydroxylase | 0.070 | ||
| CD69 | CD69 molecule | 0.068 | ||
| LAMP3 | lysosomal-associated membrane protein 3 | 0.067 | ||
| DARC | Duffy blood group, chemokine receptor | 0.058 | ||
| CCL3L3 | chemokine (C-C motif) ligand 3-like 3 | 0.057 | ||
| LAG3 | lymphocyte-activation gene 3 | 0.057 | ||
| IL2RA | interleukin 2 receptor, alpha | 0.057 | ||
| IL21R | interleukin 21 receptor | 0.056 | ||
| ADAMDEC1 | ADAM-like, decysin 1 | 0.053 | ||
| IL18RAP | interleukin 18 receptor accessory protein | 0.052 | ||
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.050 | ||
| CCL17 | chemokine (C-C motif) ligand 17 | 0.049 | Human | |
| SLAMF7 | SLAM family member 7 | 0.047 | ||
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 | 0.045 | ||
| EBI3 | Epstein-Barr virus induced 3 | 0.045 | ||
| IL1A | interleukin 1, alpha | 0.045 | ||
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.044 | ||
| MSC | musculin | 0.044 | ||
| XCL1 | chemokine (C motif) ligand 1 | 0.043 | ||
| IL32 | interleukin 32 | 0.042 | ||
| CCL21 | chemokine (C-C motif) ligand 21 | 0.042 | ||
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 0.039 | ||
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 0.038 | ||
| BCL2A1 | BCL2-related protein A1 | 0.033 | ||
| IL1RN | interleukin 1 receptor antagonist | 0.032 | ||
| BIRC3 | baculoviral IAP repeat containing 3 | 0.032 | ||
| CCL11 | chemokine (C-C motif) ligand 11 | 0.032 | Human | |
| IL12B | interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) | 0.031 | ||
| NKG7 | natural killer cell group 7 sequence | 0.031 | ||
| TNFRSF4 | tumor necrosis factor receptor superfamily, member 4 | 0.029 | ||
| CD40LG | CD40 ligand | 0.027 | ||
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 0.027 | ||
| RGS16 | regulator of G-protein signaling 16 | 0.027 | ||
| CXCL6 | chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) | 0.026 | ||
| SLAMF8 | SLAM family member 8 | 0.026 | ||
| IL2RG | interleukin 2 receptor, gamma | 0.025 | ||
| CXCR3 | chemokine (C-X-C motif) receptor 3 | 0.025 | ||
| CD2 | CD2 molecule | 0.024 | ||
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | 0.023 | ||
| RELB | v-rel reticuloendotheliosis viral oncogene homolog B | 0.023 | ||
| CD160 | CD160 molecule | 0.023 | ||
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.022 | ||
| IL10RA | interleukin 10 receptor, alpha | 0.022 | ||
| MMP9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | 0.022 | ||
| INHBA | inhibin, beta A | 0.022 | ||
| CCL23 | chemokine (C-C motif) ligand 23 | 0.021 | Human | |
| HLA-DRB4 | major histocompatibility complex, class II, DR beta 4 | 0.021 | ||
| APOC1 | apolipoprotein C-I | 0.020 | ||
| BATF | basic leucine zipper transcription factor, ATF-like | 0.020 | ||
| DPT | dermatopontin | 0.020 | ||
| CTSW | cathepsin W | 0.018 | ||
| LTA | lymphotoxin alpha (TNF superfamily, member 1) | 0.018 | ||
| IL1R2 | interleukin 1 receptor, type II | 0.018 | ||
| HSD11B1 | hydroxysteroid (11-beta) dehydrogenase 1 | 0.018 | ||
| CCRL2 | chemokine (C-C motif) receptor-like 2 | 0.018 | ||
| MMP10 | matrix metallopeptidase 10 (stromelysin 2) | 0.017 | ||
| XCL2 | chemokine (C motif) ligand 2 | 0.017 | Human | |
| SLCO2B1 | solute carrier organic anion transporter family, member 2B1 | 0.017 | ||
| C2 | complement component 2 | 0.016 | ||
| RUNX3 | runt-related transcription factor 3 | 0.016 | ||
| IL13 | interleukin 13 | 0.016 | ||
| IL3 | interleukin 3 (colony-stimulating factor, multiple) | 0.015 | ||
| IRF4 | interferon regulatory factor 4 | 0.015 | ||
| HLA-DOA | major histocompatibility complex, class II, DO alpha | 0.014 | ||
| SRGN | serglycin | 0.014 | ||
| TM7SF4 | transmembrane 7 superfamily member 4 | 0.014 | ||
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) | 0.013 | ||
| CD209 | CD209 molecule | 0.013 | ||
| CD1B | CD1b molecule | 0.013 | ||
| KLRK1 | killer cell lectin-like receptor subfamily K, member 1 | 0.013 | ||
| NNMT | nicotinamide N-methyltransferase | 0.013 | ||
| DNASE1L3 | deoxyribonuclease I-like 3 | 0.013 | ||
| DUSP2 | dual specificity phosphatase 2 | 0.012 | ||
| SLAMF1 | signaling lymphocytic activation molecule family member 1 | 0.012 | ||
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.012 | ||
| GZMK | granzyme K (granzyme 3; tryptase II) | 0.012 | ||
| LGALS2 | lectin, galactoside-binding, soluble, 2 | 0.012 | ||
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | 0.012 | ||
| LRRC32 | leucine rich repeat containing 32 | 0.012 | ||
| CD80 | CD80 molecule | 0.011 | ||
| PDPN | podoplanin | 0.011 | ||
| ICOS | inducible T-cell co-stimulator | 0.011 | ||
| CLEC10A | C-type lectin domain family 10, member A | 0.011 | ||
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 | 0.011 | ||
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 0.011 | ||
| MMP3 | matrix metallopeptidase 3 (stromelysin 1, progelatinase) | 0.010 | ||
| CST7 | cystatin F (leukocystatin) | 0.010 | ||
| KLRF1 | killer cell lectin-like receptor subfamily F, member 1 | 0.010 | ||
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | 0.010 | ||
| GZMH | granzyme H (cathepsin G-like 2, protein h-CCPX) | 0.010 | ||
| SOD2 | superoxide dismutase 2, mitochondrial | 0.010 |