IMP

Process View

Homo sapiens

25 genes annotated in human

Multi-species View

ceramide metabolic process

GO:0006672

The chemical reactions and pathways involving ceramides, any N-acylated sphingoid.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "ceramide metabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "ceramide metabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
LAMP1	lysosomal-associated membrane protein 1	0.400
PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	0.258
PRKCZ	protein kinase C, zeta	0.164	Human
TMBIM6	transmembrane BAX inhibitor motif containing 6	0.145
NOXA1	NADPH oxidase activator 1	0.134
RTN4	reticulon 4	0.117
CASP7	caspase 7, apoptosis-related cysteine peptidase	0.114
ANXA4	annexin A4	0.077
ZNF71	zinc finger protein 71	0.068
NUMB	numb homolog (Drosophila)	0.063
PARD6B	par-6 partitioning defective 6 homolog beta (C. elegans)	0.058
USP22	ubiquitin specific peptidase 22	0.058
CCDC115	coiled-coil domain containing 115	0.055
SURF4	surfeit 4	0.054
DUSP23	dual specificity phosphatase 23	0.053
SH3RF1	SH3 domain containing ring finger 1	0.051
GLB1	galactosidase, beta 1	0.049
PICK1	protein interacting with PRKCA 1	0.048
NCF1	neutrophil cytosolic factor 1	0.044
ELOVL1	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1	0.039
CTGF	connective tissue growth factor	0.038
PDPK1	3-phosphoinositide dependent protein kinase-1	0.035
XIAP	X-linked inhibitor of apoptosis	0.032
CASP3	caspase 3, apoptosis-related cysteine peptidase	0.032
ATP6V0C	ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c	0.029
NMT2	N-myristoyltransferase 2	0.027
NR1H2	nuclear receptor subfamily 1, group H, member 2	0.027
TSC22D1	TSC22 domain family, member 1	0.027
MTOR	mechanistic target of rapamycin (serine/threonine kinase)	0.027
SLC39A1	solute carrier family 39 (zinc transporter), member 1	0.026
PRKCB	protein kinase C, beta	0.026
GNS	glucosamine (N-acetyl)-6-sulfatase	0.025
CDCP1	CUB domain containing protein 1	0.024
LLGL2	lethal giant larvae homolog 2 (Drosophila)	0.023
SLC25A11	solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11	0.022
LAMP2	lysosomal-associated membrane protein 2	0.021
VHL	von Hippel-Lindau tumor suppressor	0.021
BRF2	BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-like	0.020
ASAH1	N-acylsphingosine amidohydrolase (acid ceramidase) 1	0.019
PARD6G	par-6 partitioning defective 6 homolog gamma (C. elegans)	0.019
TM9SF1	transmembrane 9 superfamily member 1	0.019
PPT1	palmitoyl-protein thioesterase 1	0.017
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.016
FUCA1	fucosidase, alpha-L- 1, tissue	0.016
ARF3	ADP-ribosylation factor 3	0.016
ADAM10	ADAM metallopeptidase domain 10	0.016
PARD3	par-3 partitioning defective 3 homolog (C. elegans)	0.015
ANXA7	annexin A7	0.015
RNF13	ring finger protein 13	0.015
ZAP70	zeta-chain (TCR) associated protein kinase 70kDa	0.015
TMEM165	transmembrane protein 165	0.015
AKT3	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)	0.015	Human
MFSD1	major facilitator superfamily domain containing 1	0.015
ATP6V0E1	ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1	0.015
CCL14	chemokine (C-C motif) ligand 14	0.015
MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1	0.014
GM2A	GM2 ganglioside activator	0.014	Mouse
ATXN1	ataxin 1	0.014
MAPK1	mitogen-activated protein kinase 1	0.014
VIM	vimentin	0.014
POFUT1	protein O-fucosyltransferase 1	0.014
ASXL1	additional sex combs like 1 (Drosophila)	0.013
NFATC2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.013
CD58	CD58 molecule	0.013
KAT2B	K(lysine) acetyltransferase 2B	0.013
BAD	BCL2-associated agonist of cell death	0.013
TRIM9	tripartite motif containing 9	0.013
CTSL1	cathepsin L1	0.013
MFSD5	major facilitator superfamily domain containing 5	0.013
GANAB	glucosidase, alpha; neutral AB	0.013
CASP9	caspase 9, apoptosis-related cysteine peptidase	0.013
MAPKAPK2	mitogen-activated protein kinase-activated protein kinase 2	0.012
PNP	purine nucleoside phosphorylase	0.012
MGAT4B	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B	0.012
ADAMTS1	ADAM metallopeptidase with thrombospondin type 1 motif, 1	0.012
SOAT1	sterol O-acyltransferase 1	0.012
APH1A	anterior pharynx defective 1 homolog A (C. elegans)	0.012
CDC37	cell division cycle 37 homolog (S. cerevisiae)	0.012
C20orf24	chromosome 20 open reading frame 24	0.012
SLC35B2	solute carrier family 35, member B2	0.012
SIGMAR1	sigma non-opioid intracellular receptor 1	0.012
SORBS2	sorbin and SH3 domain containing 2	0.012
KIAA1967	KIAA1967	0.012
TOR1B	torsin family 1, member B (torsin B)	0.012
GUSB	glucuronidase, beta	0.012
PTPLB	protein tyrosine phosphatase-like (proline instead of catalytic arginine), member b	0.012
HEXA	hexosaminidase A (alpha polypeptide)	0.012	Mouse
LLGL1	lethal giant larvae homolog 1 (Drosophila)	0.012
ALOX12B	arachidonate 12-lipoxygenase, 12R type	0.011
CPD	carboxypeptidase D	0.011
ZMPSTE24	zinc metallopeptidase (STE24 homolog, S. cerevisiae)	0.011
AUP1	ancient ubiquitous protein 1	0.011
DAZAP2	DAZ associated protein 2	0.011
TM9SF2	transmembrane 9 superfamily member 2	0.011
CCHCR1	coiled-coil alpha-helical rod protein 1	0.011
M6PR	mannose-6-phosphate receptor (cation dependent)	0.011
PPP2R5A	protein phosphatase 2, regulatory subunit B', alpha	0.011
SCAMP2	secretory carrier membrane protein 2	0.011
UGCG	UDP-glucose ceramide glucosyltransferase	0.011
ATG4C	ATG4 autophagy related 4 homolog C (S. cerevisiae)	0.011
FYN	FYN oncogene related to SRC, FGR, YES	0.011
UBE2D1	ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)	0.011
F11R	F11 receptor	0.010
DIABLO	diablo, IAP-binding mitochondrial protein	0.010
FAM103A1	family with sequence similarity 103, member A1	0.010
TM9SF3	transmembrane 9 superfamily member 3	0.010
CTSA	cathepsin A	0.010
RPTOR	regulatory associated protein of MTOR, complex 1	0.010
PEBP4	phosphatidylethanolamine-binding protein 4	0.010
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.010