IMP

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Mus musculus

3 genes annotated in mouse

Multi-species View

dna hypermethylation

GO:0044026

An increase in the epigenetic methylation of cytosine and adenosine residues in DNA.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "dna hypermethylation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "dna hypermethylation" (in gray)

Name	Description	Probability	Func Analog Organism
Dnmt3a	DNA methyltransferase 3A	1.000
Dnmt3b	DNA methyltransferase 3B	0.998	Mouse
Ezh2	enhancer of zeste homolog 2 (Drosophila)	0.997
Hells	helicase, lymphoid specific	0.968
Kdm2b	lysine (K)-specific demethylase 2B	0.875
Trim24	tripartite motif-containing 24	0.842
Trim28	tripartite motif-containing 28	0.836
Mcm4	minichromosome maintenance deficient 4 homolog (S. cerevisiae)	0.337
Axin1	axin 1	0.322
Suz12	suppressor of zeste 12 homolog (Drosophila)	0.300
Dnmt3l	DNA (cytosine-5-)-methyltransferase 3-like	0.267	Mouse
Uhrf1	ubiquitin-like, containing PHD and RING finger domains, 1	0.266
Ncoa3	nuclear receptor coactivator 3	0.175
Cbx3	chromobox homolog 3 (Drosophila HP1 gamma)	0.156	Fly
Rnf2	ring finger protein 2	0.148
Pou5f1	POU domain, class 5, transcription factor 1	0.136
Sufu	suppressor of fused homolog (Drosophila)	0.120
Hdac1	histone deacetylase 1	0.110
Stmn1	stathmin 1	0.109
Jarid2	jumonji, AT rich interactive domain 2	0.108
Rbbp4	retinoblastoma binding protein 4	0.104
Erg	avian erythroblastosis virus E-26 (v-ets) oncogene related	0.098
Apc	adenomatosis polyposis coli	0.097
Ctnnb1	catenin (cadherin associated protein), beta 1	0.095
Runx1	runt related transcription factor 1	0.095
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.090
Lig1	ligase I, DNA, ATP-dependent	0.087
Lrp6	low density lipoprotein receptor-related protein 6	0.087
Trp53	transformation related protein 53	0.065
Mtf2	metal response element binding transcription factor 2	0.064
U2af2	U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2	0.059
Brca1	breast cancer 1	0.057
Nucks1	nuclear casein kinase and cyclin-dependent kinase substrate 1	0.057
Gsk3b	glycogen synthase kinase 3 beta	0.056
Psen1	presenilin 1	0.053
Ehmt1	euchromatic histone methyltransferase 1	0.052
Crebbp	CREB binding protein	0.049
Dnmt1	DNA methyltransferase (cytosine-5) 1	0.036	Rat
Rbm14	RNA binding motif protein 14	0.036
Casp8ap2	caspase 8 associated protein 2	0.034
Hnrnpul1	heterogeneous nuclear ribonucleoprotein U-like 1	0.032
Chaf1a	chromatin assembly factor 1, subunit A (p150)	0.031
Csnk2a1	casein kinase 2, alpha 1 polypeptide	0.030
Mll3	myeloid/lymphoid or mixed-lineage leukemia 3	0.029
Ccnd1	cyclin D1	0.027
Tubb5	tubulin, beta 5	0.026
Nup155	nucleoporin 155	0.026
Parp1	poly (ADP-ribose) polymerase family, member 1	0.026
Brd4	bromodomain containing 4	0.025
Tuba1b	tubulin, alpha 1B	0.025
Rbbp7	retinoblastoma binding protein 7	0.024
Rybp	RING1 and YY1 binding protein	0.024
Myef2	myelin basic protein expression factor 2, repressor	0.023
Nup85	nucleoporin 85	0.023
Eri2	exoribonuclease 2	0.022
Ncapd3	non-SMC condensin II complex, subunit D3	0.022
Rfc2	replication factor C (activator 1) 2	0.022
Tmpo	thymopoietin	0.021
Smarcc1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	0.021
Ilf2	interleukin enhancer binding factor 2	0.021
Nanog	Nanog homeobox	0.020
Mcm2	minichromosome maintenance deficient 2 mitotin (S. cerevisiae)	0.020
Brca2	breast cancer 2	0.020
Ctbp1	C-terminal binding protein 1	0.019
Prim1	DNA primase, p49 subunit	0.018
Rad21	RAD21 homolog (S. pombe)	0.018
Supt16h	suppressor of Ty 16 homolog (S. cerevisiae)	0.018
Pold3	polymerase (DNA-directed), delta 3, accessory subunit	0.017
Skp2	S-phase kinase-associated protein 2 (p45)	0.017
C330027C09Rik	RIKEN cDNA C330027C09 gene	0.017
Mga	MAX gene associated	0.017
2610039C10Rik	RIKEN cDNA 2610039C10 gene	0.017
Hmgb1	high mobility group box 1	0.017
Htt	huntingtin	0.017
Donson	downstream neighbor of SON	0.016
Rag1	recombination activating gene 1	0.016
Zbtb33	zinc finger and BTB domain containing 33	0.016
Chd4	chromodomain helicase DNA binding protein 4	0.016
Mcm7	minichromosome maintenance deficient 7 (S. cerevisiae)	0.016
Hcfc1	host cell factor C1	0.015
Srsf4	serine/arginine-rich splicing factor 4	0.015
Fam33a	family with sequence similarity 33, member A	0.015
Gsk3a	glycogen synthase kinase 3 alpha	0.015
Smc2	structural maintenance of chromosomes 2	0.015
Bcor	BCL6 interacting corepressor	0.014
Hist1h1e	histone cluster 1, H1e	0.014
Ilf3	interleukin enhancer binding factor 3	0.014
Ctbp2	C-terminal binding protein 2	0.014
Ptma	prothymosin alpha	0.013
Ints7	integrator complex subunit 7	0.013
Ints9	integrator complex subunit 9	0.013
Chek2	CHK2 checkpoint homolog (S. pombe)	0.013
Aicda	activation-induced cytidine deaminase	0.013
Ncaph	non-SMC condensin I complex, subunit H	0.013
Cdc7	cell division cycle 7 (S. cerevisiae)	0.012
Rrm2	ribonucleotide reductase M2	0.012
Mphosph9	M-phase phosphoprotein 9	0.012
Khdrbs1	KH domain containing, RNA binding, signal transduction associated 1	0.012
Ikzf1	IKAROS family zinc finger 1	0.012
Sf3a2	splicing factor 3a, subunit 2	0.012
Carm1	coactivator-associated arginine methyltransferase 1	0.012
Tnrc6b	trinucleotide repeat containing 6b	0.011
Pola1	polymerase (DNA directed), alpha 1	0.011
D030056L22Rik	RIKEN cDNA D030056L22 gene	0.011
Rfwd3	ring finger and WD repeat domain 3	0.011
Pabpn1	poly(A) binding protein, nuclear 1	0.011
Rnps1	ribonucleic acid binding protein S1	0.011
Srrt	serrate RNA effector molecule homolog (Arabidopsis)	0.011
Whsc1	Wolf-Hirschhorn syndrome candidate 1 (human)	0.011
Snrpe	small nuclear ribonucleoprotein E	0.011
L3mbtl2	l(3)mbt-like 2 (Drosophila)	0.011
Dck	deoxycytidine kinase	0.011
Bptf	bromodomain PHD finger transcription factor	0.011
Lyz2	lysozyme 2	0.010
Cxcr4	chemokine (C-X-C motif) receptor 4	0.010
Zfp219	zinc finger protein 219	0.010