IMP
Process View
negative regulation of purine nucleotide biosynthetic process
Any process that stops, prevents or reduces the frequency, rate or extent of purine nucleotide biosynthetic processes.
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Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of purine nucleotide biosynthetic process"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Cckbr | cholecystokinin B receptor | 0.528 | ||
| Slc6a3 | solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 | 0.414 | ||
| Adrb1 | adrenergic receptor, beta 1 | 0.399 | Mouse | |
| Grm1 | glutamate receptor, metabotropic 1 | 0.324 | ||
| Pnpla2 | patatin-like phospholipase domain containing 2 | 0.321 | ||
| Cnr1 | cannabinoid receptor 1 (brain) | 0.205 | ||
| Oprm1 | opioid receptor, mu 1 | 0.188 | Rat | |
| Edn1 | endothelin 1 | 0.177 | ||
| Ece1 | endothelin converting enzyme 1 | 0.162 | ||
| Kl | klotho | 0.160 | ||
| Crhr1 | corticotropin releasing hormone receptor 1 | 0.135 | ||
| Htr1d | 5-hydroxytryptamine (serotonin) receptor 1D | 0.123 | Mouse | |
| Syn2 | synapsin II | 0.122 | ||
| Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.119 | ||
| Plxnd1 | plexin D1 | 0.110 | ||
| Drd3 | dopamine receptor D3 | 0.098 | Human Rat | |
| Htr1a | 5-hydroxytryptamine (serotonin) receptor 1A | 0.096 | Mouse | |
| Adrb2 | adrenergic receptor, beta 2 | 0.089 | Mouse | |
| Slc34a1 | solute carrier family 34 (sodium phosphate), member 1 | 0.083 | ||
| Kcna4 | potassium voltage-gated channel, shaker-related subfamily, member 4 | 0.083 | ||
| Msx1 | homeobox, msh-like 1 | 0.076 | ||
| Kcns2 | K+ voltage-gated channel, subfamily S, 2 | 0.068 | ||
| Sox10 | SRY-box containing gene 10 | 0.063 | ||
| Kcnk3 | potassium channel, subfamily K, member 3 | 0.061 | ||
| Oprk1 | opioid receptor, kappa 1 | 0.061 | ||
| Prrx1 | paired related homeobox 1 | 0.060 | ||
| Acvr1 | activin A receptor, type 1 | 0.057 | ||
| Kcna2 | potassium voltage-gated channel, shaker-related subfamily, member 2 | 0.055 | ||
| Shc3 | src homology 2 domain-containing transforming protein C3 | 0.053 | ||
| Sstr4 | somatostatin receptor 4 | 0.053 | ||
| Pparg | peroxisome proliferator activated receptor gamma | 0.052 | ||
| Fgfr1 | fibroblast growth factor receptor 1 | 0.051 | ||
| Epha6 | Eph receptor A6 | 0.048 | ||
| Kcnj6 | potassium inwardly-rectifying channel, subfamily J, member 6 | 0.047 | ||
| Oprd1 | opioid receptor, delta 1 | 0.045 | ||
| Trpc5 | transient receptor potential cation channel, subfamily C, member 5 | 0.044 | ||
| Npy2r | neuropeptide Y receptor Y2 | 0.042 | ||
| Adrb3 | adrenergic receptor, beta 3 | 0.041 | Mouse | |
| Hrh1 | histamine receptor H1 | 0.041 | ||
| Htr5a | 5-hydroxytryptamine (serotonin) receptor 5A | 0.038 | Mouse | |
| Htr4 | 5 hydroxytryptamine (serotonin) receptor 4 | 0.035 | Mouse | |
| Drd2 | dopamine receptor D2 | 0.033 | Human Rat | |
| Tectb | tectorin beta | 0.033 | ||
| Adora2a | adenosine A2a receptor | 0.033 | ||
| Prss32 | protease, serine, 32 | 0.032 | ||
| Htr1f | 5-hydroxytryptamine (serotonin) receptor 1F | 0.031 | Mouse | |
| Sncb | synuclein, beta | 0.031 | ||
| Rgs4 | regulator of G-protein signaling 4 | 0.030 | ||
| Grm2 | glutamate receptor, metabotropic 2 | 0.030 | ||
| ND6 | NADH dehydrogenase subunit 6 | 0.028 | ||
| Grid1 | glutamate receptor, ionotropic, delta 1 | 0.028 | ||
| Gabbr2 | gamma-aminobutyric acid (GABA) B receptor, 2 | 0.027 | ||
| Psg17 | pregnancy specific glycoprotein 17 | 0.027 | ||
| Sstr1 | somatostatin receptor 1 | 0.027 | ||
| Hand2 | heart and neural crest derivatives expressed transcript 2 | 0.027 | ||
| Adra2b | adrenergic receptor, alpha 2b | 0.026 | Zebrafish Mouse | |
| Zp1 | zona pellucida glycoprotein 1 | 0.026 | ||
| Opn1sw | opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan) | 0.026 | ||
| Fam164c | family with sequence similarity 164, member C | 0.025 | ||
| Cntn4 | contactin 4 | 0.025 | ||
| Adra2c | adrenergic receptor, alpha 2c | 0.025 | Mouse | |
| Fgf4 | fibroblast growth factor 4 | 0.022 | ||
| Mc3r | melanocortin 3 receptor | 0.022 | ||
| Prlhr | prolactin releasing hormone receptor | 0.022 | ||
| Dlx6 | distal-less homeobox 6 | 0.022 | ||
| Ccr1l1 | chemokine (C-C motif) receptor 1-like 1 | 0.022 | ||
| Krt32 | keratin 32 | 0.021 | ||
| Tyr | tyrosinase | 0.021 | ||
| Tgfb2 | transforming growth factor, beta 2 | 0.021 | ||
| Npy5r | neuropeptide Y receptor Y5 | 0.021 | ||
| Vip | vasoactive intestinal polypeptide | 0.021 | ||
| Ednrb | endothelin receptor type B | 0.020 | Mouse | |
| Ptprn2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.020 | ||
| Chrm1 | cholinergic receptor, muscarinic 1, CNS | 0.020 | ||
| Clcnka | chloride channel Ka | 0.019 | ||
| Csf3 | colony stimulating factor 3 (granulocyte) | 0.019 | ||
| Slc18a2 | solute carrier family 18 (vesicular monoamine), member 2 | 0.019 | ||
| Prkaca | protein kinase, cAMP dependent, catalytic, alpha | 0.019 | ||
| Gsx1 | GS homeobox 1 | 0.019 | ||
| Ppyr1 | pancreatic polypeptide receptor 1 | 0.019 | ||
| Krt84 | keratin 84 | 0.018 | ||
| Syt6 | synaptotagmin VI | 0.018 | ||
| Kcna1 | potassium voltage-gated channel, shaker-related subfamily, member 1 | 0.017 | ||
| Kcnk4 | potassium channel, subfamily K, member 4 | 0.017 | ||
| Csmd1 | CUB and Sushi multiple domains 1 | 0.017 | ||
| Rs1 | retinoschisis (X-linked, juvenile) 1 (human) | 0.017 | ||
| Isl1 | ISL1 transcription factor, LIM/homeodomain | 0.016 | ||
| Kifc2 | kinesin family member C2 | 0.016 | ||
| Ednra | endothelin receptor type A | 0.016 | ||
| Cer1 | cerberus 1 homolog (Xenopus laevis) | 0.016 | ||
| Mas1 | MAS1 oncogene | 0.016 | ||
| Mc5r | melanocortin 5 receptor | 0.016 | ||
| Sprr2f | small proline-rich protein 2F | 0.016 | ||
| Mitf | microphthalmia-associated transcription factor | 0.015 | ||
| Ar | androgen receptor | 0.015 | ||
| Nxph2 | neurexophilin 2 | 0.015 | ||
| Gpr33 | G protein-coupled receptor 33 | 0.015 | ||
| Pgr | progesterone receptor | 0.015 | ||
| Slc16a8 | solute carrier family 16 (monocarboxylic acid transporters), member 8 | 0.015 | ||
| Krt86 | keratin 86 | 0.015 | ||
| Fnip1 | folliculin interacting protein 1 | 0.015 | ||
| Atp4a | ATPase, H+/K+ exchanging, gastric, alpha polypeptide | 0.015 | ||
| Pde6a | phosphodiesterase 6A, cGMP-specific, rod, alpha | 0.014 | Mouse | |
| Rarb | retinoic acid receptor, beta | 0.014 | ||
| Ghr | growth hormone receptor | 0.014 | ||
| Slc12a1 | solute carrier family 12, member 1 | 0.014 | ||
| Cntn3 | contactin 3 | 0.014 | ||
| Slc22a6 | solute carrier family 22 (organic anion transporter), member 6 | 0.014 | ||
| Cox8c | cytochrome c oxidase, subunit VIIIc | 0.014 | ||
| Gpr83 | G protein-coupled receptor 83 | 0.013 | ||
| Chrnb2 | cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal) | 0.013 | ||
| Pspn | persephin | 0.013 | ||
| Zfr2 | zinc finger RNA binding protein 2 | 0.013 | ||
| Cdkn1b | cyclin-dependent kinase inhibitor 1B | 0.013 | ||
| Smo | smoothened homolog (Drosophila) | 0.013 | ||
| Rln1 | relaxin 1 | 0.013 | ||
| Bmp10 | bone morphogenetic protein 10 | 0.013 | ||
| Car7 | carbonic anhydrase 7 | 0.012 | ||
| Gpr27 | G protein-coupled receptor 27 | 0.012 | ||
| Otog | otogelin | 0.012 | ||
| Pex5l | peroxisomal biogenesis factor 5-like | 0.012 | ||
| Foxi3 | forkhead box I3 | 0.012 | ||
| Col19a1 | collagen, type XIX, alpha 1 | 0.012 | ||
| Fosb | FBJ osteosarcoma oncogene B | 0.012 | ||
| Kcnc1 | potassium voltage gated channel, Shaw-related subfamily, member 1 | 0.012 | ||
| Kcnj1 | potassium inwardly-rectifying channel, subfamily J, member 1 | 0.012 | ||
| Col4a3 | collagen, type IV, alpha 3 | 0.011 | ||
| Hoxb6 | homeobox B6 | 0.011 | ||
| Musk | muscle, skeletal, receptor tyrosine kinase | 0.011 | ||
| Mn1 | meningioma 1 | 0.011 | ||
| Sez6 | seizure related gene 6 | 0.011 | ||
| Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 0.011 | ||
| Rcvrn | recoverin | 0.011 | ||
| Slc17a1 | solute carrier family 17 (sodium phosphate), member 1 | 0.010 | ||
| Crygs | crystallin, gamma S | 0.010 | ||
| Olfr71 | olfactory receptor 71 | 0.010 | ||
| Cacng5 | calcium channel, voltage-dependent, gamma subunit 5 | 0.010 | ||
| Nkx3-1 | NK-3 transcription factor, locus 1 (Drosophila) | 0.010 | ||
| B3gat1 | beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) | 0.010 |