IMP

Process View

Mus musculus

7 genes annotated in mouse

sphingolipid catabolic process

The chemical reactions and pathways resulting in the breakdown of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "sphingolipid catabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "sphingolipid catabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
Gusb	glucuronidase, beta	0.472
Lgmn	legumain	0.468
Ctsz	cathepsin Z	0.445
Grn	granulin	0.327
Npc2	Niemann Pick type C2	0.240
Dpp7	dipeptidylpeptidase 7	0.220
Asah1	N-acylsphingosine amidohydrolase 1	0.218
0610031J06Rik	RIKEN cDNA 0610031J06 gene	0.215
Gns	glucosamine (N-acetyl)-6-sulfatase	0.205
Mfsd1	major facilitator superfamily domain containing 1	0.182
Tcn2	transcobalamin 2	0.158
Scpep1	serine carboxypeptidase 1	0.125
Ptpn22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.122
Fuca1	fucosidase, alpha-L- 1, tissue	0.120
Man2b1	mannosidase 2, alpha B1	0.120
Naglu	alpha-N-acetylglucosaminidase (Sanfilippo disease IIIB)	0.105
Gsta3	glutathione S-transferase, alpha 3	0.103
Lamp1	lysosomal-associated membrane protein 1	0.089
Aadac	arylacetamide deacetylase (esterase)	0.085
Clcn5	chloride channel 5	0.083
Tpp1	tripeptidyl peptidase I	0.076
Ctsb	cathepsin B	0.068
Naga	N-acetyl galactosaminidase, alpha	0.068
Ctsa	cathepsin A	0.068
Blnk	B-cell linker	0.058
Psap	prosaposin	0.051
Arid5b	AT rich interactive domain 5B (MRF1-like)	0.045
Anxa4	annexin A4	0.041
Cndp2	CNDP dipeptidase 2 (metallopeptidase M20 family)	0.039
Litaf	LPS-induced TN factor	0.036
Glb1	galactosidase, beta 1	0.035
Rnh1	ribonuclease/angiogenin inhibitor 1	0.033
Plekha1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1	0.033
Gba	glucosidase, beta, acid	0.033	Human
Cstb	cystatin B	0.032
Ces1f	carboxylesterase 1F	0.029
Tiparp	TCDD-inducible poly(ADP-ribose) polymerase	0.029
Renbp	renin binding protein	0.028
Pold4	polymerase (DNA-directed), delta 4	0.028
Igh	immunoglobulin heavy chain complex	0.027
P2rx4	purinergic receptor P2X, ligand-gated ion channel 4	0.027
Lipa	lysosomal acid lipase A	0.026
Sat1	spermidine/spermine N1-acetyl transferase 1	0.026
Scamp2	secretory carrier membrane protein 2	0.026
Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	0.025
Lamp2	lysosomal-associated membrane protein 2	0.025
Coro1b	coronin, actin binding protein 1B	0.024
Ctsh	cathepsin H	0.024
Siae	sialic acid acetylesterase	0.023
Manba	mannosidase, beta A, lysosomal	0.022
Ces1e	carboxylesterase 1E	0.022	Mouse
Sirpa	signal-regulatory protein alpha	0.022
Plg	plasminogen	0.021
Dscr3	Down syndrome critical region gene 3	0.021
Ctsd	cathepsin D	0.021
Soat1	sterol O-acyltransferase 1	0.021
Elovl1	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1	0.020
Inmt	indolethylamine N-methyltransferase	0.020
Prr13	proline rich 13	0.020
Wwox	WW domain-containing oxidoreductase	0.018
Fabp1	fatty acid binding protein 1, liver	0.018
Hexb	hexosaminidase B	0.018
Cd68	CD68 antigen	0.017
Sgpl1	sphingosine phosphate lyase 1	0.017	Human Fly
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.017
Ppara	peroxisome proliferator activated receptor alpha	0.016
Sult1d1	sulfotransferase family 1D, member 1	0.016
Iah1	isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae)	0.016
Rab7l1	RAB7, member RAS oncogene family-like 1	0.016
Edem1	ER degradation enhancer, mannosidase alpha-like 1	0.015
Rragc	Ras-related GTP binding C	0.015
Adig	adipogenin	0.015
Ces1d	carboxylesterase 1D	0.015	Mouse
Nagk	N-acetylglucosamine kinase	0.014
Sdf2	stromal cell derived factor 2	0.014
Ldb3	LIM domain binding 3	0.014
Tnfrsf13b	tumor necrosis factor receptor superfamily, member 13b	0.014
Shisa5	shisa homolog 5 (Xenopus laevis)	0.014
Uap1l1	UDP-N-acteylglucosamine pyrophosphorylase 1-like 1	0.014
Gpr137b	G protein-coupled receptor 137B	0.014
Gm2a	GM2 ganglioside activator protein	0.013
Ttc36	tetratricopeptide repeat domain 36	0.013
Otc	ornithine transcarbamylase	0.013
Atp6v0e	ATPase, H+ transporting, lysosomal V0 subunit E	0.013
Tcirg1	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3	0.013
Sumf1	sulfatase modifying factor 1	0.013
Ifi30	interferon gamma inducible protein 30	0.013
Ces1g	carboxylesterase 1G	0.013
Cyp3a13	cytochrome P450, family 3, subfamily a, polypeptide 13	0.013
Atp6ap2	ATPase, H+ transporting, lysosomal accessory protein 2	0.012
Cd19	CD19 antigen	0.012
Atp6ap1	ATPase, H+ transporting, lysosomal accessory protein 1	0.012
Gla	galactosidase, alpha	0.012
Amy2a4	amylase 2a4	0.012
Fmo1	flavin containing monooxygenase 1	0.012
Hexa	hexosaminidase A	0.012
Cd79b	CD79B antigen	0.011
Galc	galactosylceramidase	0.011
Acp2	acid phosphatase 2, lysosomal	0.011
Cln5	ceroid-lipofuscinosis, neuronal 5	0.011
Eif2ak3	eukaryotic translation initiation factor 2 alpha kinase 3	0.011
Pck1	phosphoenolpyruvate carboxykinase 1, cytosolic	0.011
Sec14l4	SEC14-like 4 (S. cerevisiae)	0.011
Neu1	neuraminidase 1	0.011
Sult1b1	sulfotransferase family 1B, member 1	0.011
Schip1	schwannomin interacting protein 1	0.011
Chrnb2	cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)	0.010
Pld3	phospholipase D family, member 3	0.010
Clta	clathrin, light polypeptide (Lca)	0.010
Itgav	integrin alpha V	0.010
Cyp2c68	cytochrome P450, family 2, subfamily c, polypeptide 68	0.010
Pgam2	phosphoglycerate mutase 2	0.010
Adra2a	adrenergic receptor, alpha 2a	0.010