IMP

Process View

Mus musculus

10 genes annotated in mouse

cerebellar granular layer morphogenesis

The process in which the anatomical structure of the cerebellar granular layer is generated and organized. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cerebellar granular layer morphogenesis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "cerebellar granular layer morphogenesis" (in gray)

Name	Description	Probability	Func Analog Organism
C1qa	complement component 1, q subcomponent, alpha polypeptide	0.963	Mouse
Lhx1	LIM homeobox protein 1	0.936
Pax2	paired box gene 2	0.926
Cbln1	cerebellin 1 precursor protein	0.877
C1qc	complement component 1, q subcomponent, C chain	0.795	Mouse
Emx1	empty spiracles homolog 1 (Drosophila)	0.725
Nrxn1	neurexin I	0.634
C1qb	complement component 1, q subcomponent, beta polypeptide	0.606	Mouse
Shh	sonic hedgehog	0.604
Otx2	orthodenticle homolog 2 (Drosophila)	0.578
Fzd8	frizzled homolog 8 (Drosophila)	0.532
Gli3	GLI-Kruppel family member GLI3	0.510
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.491
Emx2	empty spiracles homolog 2 (Drosophila)	0.456
Rarb	retinoic acid receptor, beta	0.453
Nfic	nuclear factor I/C	0.363	Mouse
Nfix	nuclear factor I/X	0.331
Grid2	glutamate receptor, ionotropic, delta 2	0.319
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.305
Fgf8	fibroblast growth factor 8	0.245
En1	engrailed 1	0.212
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.203
Nog	noggin	0.181
Gdnf	glial cell line derived neurotrophic factor	0.144
Wnt6	wingless-related MMTV integration site 6	0.143	Mouse
Pou3f3	POU domain, class 3, transcription factor 3	0.143
Fgfr1	fibroblast growth factor receptor 1	0.134
Wnt3a	wingless-related MMTV integration site 3A	0.131	Mouse
Lmx1a	LIM homeobox transcription factor 1 alpha	0.123
Lhx5	LIM homeobox protein 5	0.119
Nfia	nuclear factor I/A	0.119	Mouse
Vax1	ventral anterior homeobox containing gene 1	0.115
Mtap2	microtubule-associated protein 2	0.114
Ncor2	nuclear receptor co-repressor 2	0.113
Pax8	paired box gene 8	0.106
T	brachyury	0.105
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.093
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.078
Rarg	retinoic acid receptor, gamma	0.077
Nfib	nuclear factor I/B	0.076	Mouse
Tyrobp	TYRO protein tyrosine kinase binding protein	0.076
Gpr50	G-protein-coupled receptor 50	0.072
Atp6v1a	ATPase, H+ transporting, lysosomal V1 subunit A	0.069
Wnt4	wingless-related MMTV integration site 4	0.067	Mouse
Gabrb3	gamma-aminobutyric acid (GABA) A receptor, subunit beta 3	0.067
Nos1	nitric oxide synthase 1, neuronal	0.063
Fzd10	frizzled homolog 10 (Drosophila)	0.062
Kcnd3	potassium voltage-gated channel, Shal-related family, member 3	0.060
Vstm2b	V-set and transmembrane domain containing 2B	0.057
Wnt7a	wingless-related MMTV integration site 7A	0.057
Adra2a	adrenergic receptor, alpha 2a	0.052
Adcy9	adenylate cyclase 9	0.051
Des	desmin	0.050
Hoxc9	homeobox C9	0.050
Hoxd11	homeobox D11	0.049
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.048
Wnt2b	wingless related MMTV integration site 2b	0.047	Mouse
Pax3	paired box gene 3	0.046
Hoxa13	homeobox A13	0.045
Wnt1	wingless-related MMTV integration site 1	0.045	Mouse
Ctnnb1	catenin (cadherin associated protein), beta 1	0.044
Wnt10b	wingless related MMTV integration site 10b	0.044	Mouse
Bmp7	bone morphogenetic protein 7	0.044
Gli1	GLI-Kruppel family member GLI1	0.044
Atg13	ATG13 autophagy related 13 homolog (S. cerevisiae)	0.042
Otx1	orthodenticle homolog 1 (Drosophila)	0.041
Fgf18	fibroblast growth factor 18	0.041
Uncx	UNC homeobox	0.040
Sox1	SRY-box containing gene 1	0.039
Irs1	insulin receptor substrate 1	0.039
Foxd2	forkhead box D2	0.039
Lrp6	low density lipoprotein receptor-related protein 6	0.039
Hoxa2	homeobox A2	0.038
Gli2	GLI-Kruppel family member GLI2	0.038
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.036
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.035
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.035
Zfp771	zinc finger protein 771	0.035
Grin2d	glutamate receptor, ionotropic, NMDA2D (epsilon 4)	0.035
Tbx1	T-box 1	0.035
Dmgdh	dimethylglycine dehydrogenase precursor	0.034
Cacna1a	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	0.034
Col13a1	collagen, type XIII, alpha 1	0.034
Hmx3	H6 homeobox 3	0.033
Prrx2	paired related homeobox 2	0.033
Fgf5	fibroblast growth factor 5	0.033
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.033
Wnt9a	wingless-type MMTV integration site 9A	0.033	Mouse
Hsd11b2	hydroxysteroid 11-beta dehydrogenase 2	0.032
Mmp15	matrix metallopeptidase 15	0.032
Arx	aristaless related homeobox	0.032
Krtdap	keratinocyte differentiation associated protein	0.032
Gucy2e	guanylate cyclase 2e	0.031
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.031
Ly86	lymphocyte antigen 86	0.031
Fgf3	fibroblast growth factor 3	0.029
Thra	thyroid hormone receptor alpha	0.029
Sqstm1	sequestosome 1	0.029
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.028
Porcn	porcupine homolog (Drosophila)	0.028
Pou3f2	POU domain, class 3, transcription factor 2	0.027
Zfp703	zinc finger protein 703	0.027
Kif1b	kinesin family member 1B	0.027
Amh	anti-Mullerian hormone	0.026
Wnt11	wingless-related MMTV integration site 11	0.026	Mouse
Rora	RAR-related orphan receptor alpha	0.026
Fzd4	frizzled homolog 4 (Drosophila)	0.026
Cdx1	caudal type homeobox 1	0.026
Il11	interleukin 11	0.025
Csf1r	colony stimulating factor 1 receptor	0.024
Trp73	transformation related protein 73	0.024
Pou3f4	POU domain, class 3, transcription factor 4	0.024
Msx2	homeobox, msh-like 2	0.024
P2rx6	purinergic receptor P2X, ligand-gated ion channel, 6	0.024
Barx1	BarH-like homeobox 1	0.024
Foxf1a	forkhead box F1a	0.024
Wnt3	wingless-related MMTV integration site 3	0.023	Mouse
Lmx1b	LIM homeobox transcription factor 1 beta	0.023
Cldn3	claudin 3	0.023
Htra3	HtrA serine peptidase 3	0.022
Mrc1	mannose receptor, C type 1	0.022
Gas1	growth arrest specific 1	0.022
Gata6	GATA binding protein 6	0.022
Sim2	single-minded homolog 2 (Drosophila)	0.022
Nrxn3	neurexin III	0.021	Mouse
Btbd17	BTB (POZ) domain containing 17	0.021
Sesn2	sestrin 2	0.021
Cacna2d1	calcium channel, voltage-dependent, alpha2/delta subunit 1	0.020
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.020
Fzd7	frizzled homolog 7 (Drosophila)	0.020
Fgf15	fibroblast growth factor 15	0.020
Kcnj6	potassium inwardly-rectifying channel, subfamily J, member 6	0.020
Ppp3ca	protein phosphatase 3, catalytic subunit, alpha isoform	0.020
Zfp651	zinc finger protein 651	0.019
Lhx3	LIM homeobox protein 3	0.019
Pten	phosphatase and tensin homolog	0.019
Foxq1	forkhead box Q1	0.019
En2	engrailed 2	0.019
Gja3	gap junction protein, alpha 3	0.019
Nxph4	neurexophilin 4	0.018
Grid1	glutamate receptor, ionotropic, delta 1	0.018	Mouse
Onecut1	one cut domain, family member 1	0.018
Dlg4	discs, large homolog 4 (Drosophila)	0.018
Ush1g	Usher syndrome 1G homolog (human)	0.017
Esr1	estrogen receptor 1 (alpha)	0.017
Pitx3	paired-like homeodomain transcription factor 3	0.017
Ctss	cathepsin S	0.017
Cacna1g	calcium channel, voltage-dependent, T type, alpha 1G subunit	0.017
Pax6	paired box gene 6	0.017
AI118078	expressed sequence AI118078	0.017
Aif1	allograft inflammatory factor 1	0.017
Efna2	ephrin A2	0.017
Sftpc	surfactant associated protein C	0.017
Fosl2	fos-like antigen 2	0.017
Ephb2	Eph receptor B2	0.016
Wt1	Wilms tumor 1 homolog	0.016
BC024139	cDNA sequence BC024139	0.016
Ebf3	early B-cell factor 3	0.016
Serinc1	serine incorporator 1	0.016
Emp2	epithelial membrane protein 2	0.016
Papln	papilin, proteoglycan-like sulfated glycoprotein	0.016
Pou3f1	POU domain, class 3, transcription factor 1	0.016
Npas3	neuronal PAS domain protein 3	0.016
Efnb3	ephrin B3	0.016
Amhr2	anti-Mullerian hormone type 2 receptor	0.016
Kcnc3	potassium voltage gated channel, Shaw-related subfamily, member 3	0.016
Neurog3	neurogenin 3	0.016
Crhr1	corticotropin releasing hormone receptor 1	0.016
Adra2c	adrenergic receptor, alpha 2c	0.016
Nkx1-2	NK1 transcription factor related, locus 2 (Drosophila)	0.015
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.015
Igf1	insulin-like growth factor 1	0.015
Hoxd13	homeobox D13	0.015
Pbx1	pre B-cell leukemia transcription factor 1	0.015
Nr2f1	nuclear receptor subfamily 2, group F, member 1	0.015
Mobkl1b	MOB1, Mps One Binder kinase activator-like 1B (yeast)	0.015
Gdf10	growth differentiation factor 10	0.015
2610109H07Rik	RIKEN cDNA 2610109H07 gene	0.014
Grid2ip	glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein 1	0.014
Hoxa10	homeobox A10	0.014
Slc32a1	solute carrier family 32 (GABA vesicular transporter), member 1	0.014
Ar	androgen receptor	0.014
Hes5	hairy and enhancer of split 5 (Drosophila)	0.014
Foxl2	forkhead box L2	0.014
Adra2b	adrenergic receptor, alpha 2b	0.014
Ank1	ankyrin 1, erythroid	0.014
Rpe65	retinal pigment epithelium 65	0.014
Hoxa4	homeobox A4	0.014
Zbtb20	zinc finger and BTB domain containing 20	0.014
Scube1	signal peptide, CUB domain, EGF-like 1	0.014
Ppara	peroxisome proliferator activated receptor alpha	0.014
Sh3pxd2a	SH3 and PX domains 2A	0.014
Fgfr4	fibroblast growth factor receptor 4	0.014
Itfg1	integrin alpha FG-GAP repeat containing 1	0.014
Tctex1d4	Tctex1 domain containing 4	0.014
Pnoc	prepronociceptin	0.013
Cux2	cut-like homeobox 2	0.013
Sema6a	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.013
Nrtn	neurturin	0.013
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.013
Car3	carbonic anhydrase 3	0.013
Foxb1	forkhead box B1	0.013
Ret	ret proto-oncogene	0.013
Kcnj12	potassium inwardly-rectifying channel, subfamily J, member 12	0.013
Sh3bgrl	SH3-binding domain glutamic acid-rich protein like	0.013
Gpr27	G protein-coupled receptor 27	0.013
Sox2	SRY-box containing gene 2	0.013
Vstm2l	V-set and transmembrane domain containing 2-like	0.013
Insm1	insulinoma-associated 1	0.013
Chrd	chordin	0.013
Zic1	zinc finger protein of the cerebellum 1	0.013
Zic4	zinc finger protein of the cerebellum 4	0.013
Npas1	neuronal PAS domain protein 1	0.013
Zfp787	zinc finger protein 787	0.013
Epha4	Eph receptor A4	0.012
Drd2	dopamine receptor D2	0.012
Fcgrt	Fc receptor, IgG, alpha chain transporter	0.012
Gabra5	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 5	0.012
Slc8a2	solute carrier family 8 (sodium/calcium exchanger), member 2	0.012
Epha1	Eph receptor A1	0.012
Nrxn2	neurexin II	0.012	Mouse
Zbtb12	zinc finger and BTB domain containing 12	0.012
Dcc	deleted in colorectal carcinoma	0.012
Ntrk3	neurotrophic tyrosine kinase, receptor, type 3	0.011
Hoxc5	homeobox C5	0.011
Kcnj11	potassium inwardly rectifying channel, subfamily J, member 11	0.011
Gabrb2	gamma-aminobutyric acid (GABA) A receptor, subunit beta 2	0.011
Pou4f3	POU domain, class 4, transcription factor 3	0.011
Nrg3	neuregulin 3	0.011
Rara	retinoic acid receptor, alpha	0.011
Kcnb1	potassium voltage gated channel, Shab-related subfamily, member 1	0.011
Tcf7l1	transcription factor 7-like 1 (T-cell specific, HMG box)	0.011
Kcne1l	potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene	0.011
Zbtb7c	zinc finger and BTB domain containing 7C	0.011
Shisa9	shisa homolog 9 (Xenopus laevis)	0.011
Efna5	ephrin A5	0.011
Hoxa11	homeobox A11	0.011
Alx4	aristaless-like homeobox 4	0.011
Cib2	calcium and integrin binding family member 2	0.011
Sox3	SRY-box containing gene 3	0.011
Cdh10	cadherin 10	0.011
Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.011
Rem1	rad and gem related GTP binding protein 1	0.011
Gsk3b	glycogen synthase kinase 3 beta	0.011
Tmem132e	transmembrane protein 132E	0.011
Capza2	capping protein (actin filament) muscle Z-line, alpha 2	0.010
Slc16a2	solute carrier family 16 (monocarboxylic acid transporters), member 2	0.010
Kcnh3	potassium voltage-gated channel, subfamily H (eag-related), member 3	0.010
Ntn3	netrin 3	0.010
Bnc1	basonuclin 1	0.010
Twist1	twist homolog 1 (Drosophila)	0.010
Hspb7	heat shock protein family, member 7 (cardiovascular)	0.010
Adamts18	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 18	0.010
Zfp316	zinc finger protein 316	0.010
Adrb1	adrenergic receptor, beta 1	0.010
Sox9	SRY-box containing gene 9	0.010
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.010
Irx3	Iroquois related homeobox 3 (Drosophila)	0.010
Folr2	folate receptor 2 (fetal)	0.010