IMP

Process View

Mus musculus

7 genes annotated in mouse

exocrine pancreas development

The process whose specific outcome is the progression of the exocrine pancreas over time, from its formation to the mature structure. The exocrine pancreas produces and store zymogens of digestive enzymes, such as chymotrypsinogen and trypsinogen in the acinar cells.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "exocrine pancreas development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "exocrine pancreas development" (in gray)

Name	Description	Probability	Func Analog Organism
Ins2	insulin II	0.983	Mouse
Grb10	growth factor receptor bound protein 10	0.952
Cela3b	chymotrypsin-like elastase family, member 3B	0.906	Mouse
Hdac1	histone deacetylase 1	0.589	Zebrafish
Sin3a	transcriptional regulator, SIN3A (yeast)	0.567
Dnmt3a	DNA methyltransferase 3A	0.544
Prss2	protease, serine, 2	0.525
Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus	0.486
Sycn	syncollin	0.475
Igf2r	insulin-like growth factor 2 receptor	0.435
Ctrb1	chymotrypsinogen B1	0.390	Mouse
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.389
2210010C04Rik	RIKEN cDNA 2210010C04 gene	0.365
Ptf1a	pancreas specific transcription factor, 1a	0.357	Zebrafish Rat
Tcfap2a	transcription factor AP-2, alpha	0.325
Ins1	insulin I	0.216	Mouse
Reg2	regenerating islet-derived 2	0.212
Fgfr1	fibroblast growth factor receptor 1	0.210
Ctrl	chymotrypsin-like	0.200	Mouse
Cel	carboxyl ester lipase	0.195
Insr	insulin receptor	0.192
Cpa1	carboxypeptidase A1	0.179
Reg1	regenerating islet-derived 1	0.173
Hand2	heart and neural crest derivatives expressed transcript 2	0.158
Dll1	delta-like 1 (Drosophila)	0.150
Rbbp4	retinoblastoma binding protein 4	0.145
Ezh2	enhancer of zeste homolog 2 (Drosophila)	0.143
Clps	colipase, pancreatic	0.141
Gfi1b	growth factor independent 1B	0.122
Pax3	paired box gene 3	0.099
Gm13011	predicted gene 13011	0.092	Mouse
Tff2	trefoil factor 2 (spasmolytic protein 1)	0.090
Acvr1	activin A receptor, type 1	0.087
Notch2	Notch gene homolog 2 (Drosophila)	0.081
Cdkn1c	cyclin-dependent kinase inhibitor 1C (P57)	0.077
Sox9	SRY-box containing gene 9	0.065
Htr3a	5-hydroxytryptamine (serotonin) receptor 3A	0.064
Rorb	RAR-related orphan receptor beta	0.064
Lep	leptin	0.063
Irs2	insulin receptor substrate 2	0.061
Onecut1	one cut domain, family member 1	0.061
Cuzd1	CUB and zona pellucida-like domains 1	0.058
Pnliprp1	pancreatic lipase related protein 1	0.050
Cd6	CD6 antigen	0.050
Zg16	zymogen granule protein 16	0.049
Fgfr2	fibroblast growth factor receptor 2	0.046
Pnliprp2	pancreatic lipase-related protein 2	0.045
Rnase1	ribonuclease, RNase A family, 1 (pancreatic)	0.044
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.041
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.041
Msx1	homeobox, msh-like 1	0.040
Nedd4	neural precursor cell expressed, developmentally down-regulated 4	0.038
Ghr	growth hormone receptor	0.037
Cela2a	chymotrypsin-like elastase family, member 2A	0.036	Mouse
Esr1	estrogen receptor 1 (alpha)	0.035
Pax6	paired box gene 6	0.035
Igf1r	insulin-like growth factor I receptor	0.034
Zeb1	zinc finger E-box binding homeobox 1	0.033
Cav1	caveolin 1, caveolae protein	0.032
Phox2b	paired-like homeobox 2b	0.032
Inhbc	inhibin beta-C	0.031
Reg3a	regenerating islet-derived 3 alpha	0.030
Gm10334	predicted gene 10334	0.030
Tcof1	Treacher Collins Franceschetti syndrome 1, homolog	0.030
Ubtf	upstream binding transcription factor, RNA polymerase I	0.029
Lepr	leptin receptor	0.028
Prss3	protease, serine, 3	0.028
Dnmt3l	DNA (cytosine-5-)-methyltransferase 3-like	0.027
Tff1	trefoil factor 1	0.027
Try5	trypsin 5	0.026
Gsc	goosecoid homeobox	0.026
Ednra	endothelin receptor type A	0.026
Foxo1	forkhead box O1	0.026
Sirt1	sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)	0.025
Tacr2	tachykinin receptor 2	0.025
Reg3d	regenerating islet-derived 3 delta	0.024
Neurod1	neurogenic differentiation 1	0.024
Nos1	nitric oxide synthase 1, neuronal	0.024
Ctrc	chymotrypsin C (caldecrin)	0.023	Mouse
Pten	phosphatase and tensin homolog	0.023
Mesp1	mesoderm posterior 1	0.023
Dmbt1	deleted in malignant brain tumors 1	0.023
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.022
Dscam	Down syndrome cell adhesion molecule	0.021
Pnlip	pancreatic lipase	0.021
Mogat2	monoacylglycerol O-acyltransferase 2	0.021
Parp1	poly (ADP-ribose) polymerase family, member 1	0.020
Disp1	dispatched homolog 1 (Drosophila)	0.020
Mta2	metastasis-associated gene family, member 2	0.020
Ghrl	ghrelin	0.019
Insm1	insulinoma-associated 1	0.019
Pou2f2	POU domain, class 2, transcription factor 2	0.018
Arid3a	AT rich interactive domain 3A (BRIGHT-like)	0.018
Prg2	proteoglycan 2, bone marrow	0.017
Mybbp1a	MYB binding protein (P160) 1a	0.017
Chrd	chordin	0.017
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.017
Serpina10	serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10	0.017
Shh	sonic hedgehog	0.017
Dlk1	delta-like 1 homolog (Drosophila)	0.017
Tal1	T-cell acute lymphocytic leukemia 1	0.016
Psen2	presenilin 2	0.016
Lig1	ligase I, DNA, ATP-dependent	0.016
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.016
Prss42	protease, serine, 42	0.016
Hoxa13	homeobox A13	0.015
Hand1	heart and neural crest derivatives expressed transcript 1	0.015
Edn3	endothelin 3	0.014
Tff3	trefoil factor 3, intestinal	0.014
Kcnk7	potassium channel, subfamily K, member 7	0.014
Madcam1	mucosal vascular addressin cell adhesion molecule 1	0.014
Myod1	myogenic differentiation 1	0.014
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.014
Ctla4	cytotoxic T-lymphocyte-associated protein 4	0.014
Gck	glucokinase	0.014
Bmp2	bone morphogenetic protein 2	0.013
Klk1	kallikrein 1	0.013
Pparg	peroxisome proliferator activated receptor gamma	0.013
Drd2	dopamine receptor D2	0.013
Ikzf4	IKAROS family zinc finger 4	0.013
Gcg	glucagon	0.013
Pax4	paired box gene 4	0.013
Hrh2	histamine receptor H2	0.012
Krt71	keratin 71	0.012
Odf3	outer dense fiber of sperm tails 3	0.012
Ret	ret proto-oncogene	0.012
Sik3	SIK family kinase 3	0.012
Pga5	pepsinogen 5, group I	0.012
Gcgr	glucagon receptor	0.012
Folr4	folate receptor 4 (delta)	0.012
Brca1	breast cancer 1	0.012
Efnb2	ephrin B2	0.012
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.011
Hoxb3	homeobox B3	0.011
Gdf11	growth differentiation factor 11	0.011
Ece1	endothelin converting enzyme 1	0.011
Cpa2	carboxypeptidase A2, pancreatic	0.011
Phox2a	paired-like homeobox 2a	0.011
Otx2	orthodenticle homolog 2 (Drosophila)	0.010
Hes1	hairy and enhancer of split 1 (Drosophila)	0.010