IMP

Process View

Mus musculus

12 genes annotated in mouse

striated muscle cell apoptotic process

A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a striated muscle cell and result in its death. Striated muscle cells make up striated muscle fibers which are divided by transverse bands into striations.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "striated muscle cell apoptotic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "striated muscle cell apoptotic process" (in gray)

Name	Description	Probability	Func Analog Organism
Hand2	heart and neural crest derivatives expressed transcript 2	0.768
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.660
Hand1	heart and neural crest derivatives expressed transcript 1	0.625	Mouse
Isl1	ISL1 transcription factor, LIM/homeodomain	0.442
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.427
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.397
Gata1	GATA binding protein 1	0.312
Gata4	GATA binding protein 4	0.277
Mdm2	transformed mouse 3T3 cell double minute 2	0.259
Emx1	empty spiracles homolog 1 (Drosophila)	0.254
Sfrp2	secreted frizzled-related protein 2	0.232
Foxc2	forkhead box C2	0.143
Flii	flightless I homolog (Drosophila)	0.143
Shh	sonic hedgehog	0.138
Hoxd13	homeobox D13	0.120
Pten	phosphatase and tensin homolog	0.119
Fgf8	fibroblast growth factor 8	0.108
Mecom	MDS1 and EVI1 complex locus	0.089
Otx2	orthodenticle homolog 2 (Drosophila)	0.087
Nkx6-1	NK6 homeobox 1	0.076
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.075
Hey1	hairy/enhancer-of-split related with YRPW motif 1	0.074	Mouse
Prph2	peripherin 2	0.070
Sfrp1	secreted frizzled-related protein 1	0.066	Mouse
Epor	erythropoietin receptor	0.065
Rxra	retinoid X receptor alpha	0.063
Nkx3-2	NK3 homeobox 2	0.062	Mouse
Pdx1	pancreatic and duodenal homeobox 1	0.061
En1	engrailed 1	0.059
Insm1	insulinoma-associated 1	0.059
Vegfa	vascular endothelial growth factor A	0.058
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.056
Srrm4	serine/arginine repetitive matrix 4	0.055
Mesp1	mesoderm posterior 1	0.053
Ntf3	neurotrophin 3	0.050
Grin2b	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	0.050
Pax6	paired box gene 6	0.049
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.049
Sfrp5	secreted frizzled-related sequence protein 5	0.045	Mouse
Fgf16	fibroblast growth factor 16	0.040
Sox2	SRY-box containing gene 2	0.039
Actn2	actinin alpha 2	0.038
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.037
Ntrk3	neurotrophic tyrosine kinase, receptor, type 3	0.036
Rara	retinoic acid receptor, alpha	0.034
Lhx5	LIM homeobox protein 5	0.033
Tbx20	T-box 20	0.033
Tbx5	T-box 5	0.031
Hes2	hairy and enhancer of split 2 (Drosophila)	0.031
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.030
Gnrhr	gonadotropin releasing hormone receptor	0.030
Foxp3	forkhead box P3	0.030
Neurog3	neurogenin 3	0.029	Mouse
Nsf	N-ethylmaleimide sensitive fusion protein	0.028
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.028
Msx1	homeobox, msh-like 1	0.027
Hoxd12	homeobox D12	0.027
Gnai2	guanine nucleotide binding protein (G protein), alpha inhibiting 2	0.027
Alx3	aristaless-like homeobox 3	0.026
Fgf15	fibroblast growth factor 15	0.026
Foxe1	forkhead box E1	0.025
Plec	plectin	0.025
Kcnj11	potassium inwardly rectifying channel, subfamily J, member 11	0.024
Gli2	GLI-Kruppel family member GLI2	0.024
Pou4f3	POU domain, class 4, transcription factor 3	0.023
Otp	orthopedia homolog (Drosophila)	0.023
Cited1	Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1	0.022
Vax1	ventral anterior homeobox containing gene 1	0.022
Tcf3	transcription factor 3	0.022
Hspa8	heat shock protein 8	0.022
Fgf17	fibroblast growth factor 17	0.022
Ascl2	achaete-scute complex homolog 2 (Drosophila)	0.022
Mtap7d1	microtubule-associated protein 7 domain containing 1	0.021
Igfbpl1	insulin-like growth factor binding protein-like 1	0.021
Nkx2-9	NK2 transcription factor related, locus 9 (Drosophila)	0.019	Mouse
Gnb2	guanine nucleotide binding protein (G protein), beta 2	0.019
Arhgdia	Rho GDP dissociation inhibitor (GDI) alpha	0.019
Ebf2	early B-cell factor 2	0.019
Mapk8	mitogen-activated protein kinase 8	0.019
Six6	sine oculis-related homeobox 6 homolog (Drosophila)	0.018
Dlx2	distal-less homeobox 2	0.018
Actn4	actinin alpha 4	0.018
Pax9	paired box gene 9	0.018
Nhlh1	nescient helix loop helix 1	0.018	Mouse
Glis3	GLIS family zinc finger 3	0.018
Ebf3	early B-cell factor 3	0.018
Zic1	zinc finger protein of the cerebellum 1	0.017
Neurod1	neurogenic differentiation 1	0.017	Mouse
Tcfap2a	transcription factor AP-2, alpha	0.017
Kiss1	KiSS-1 metastasis-suppressor	0.017
Utf1	undifferentiated embryonic cell transcription factor 1	0.017
Hspa1b	heat shock protein 1B	0.016
Foxa2	forkhead box A2	0.016
Grm1	glutamate receptor, metabotropic 1	0.016
Hsp90ab1	heat shock protein 90 alpha (cytosolic), class B member 1	0.016
Ldb3	LIM domain binding 3	0.016
Arx	aristaless related homeobox	0.016
Hr	hairless	0.016
Hes5	hairy and enhancer of split 5 (Drosophila)	0.016
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.016
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.015
Hsph1	heat shock 105kDa/110kDa protein 1	0.015
Tcf15	transcription factor 15	0.015	Mouse
Cyp19a1	cytochrome P450, family 19, subfamily a, polypeptide 1	0.015
Sipa1	signal-induced proliferation associated gene 1	0.015
1700065I17Rik	RIKEN cDNA 1700065I17 gene	0.015
Mnx1	motor neuron and pancreas homeobox 1	0.015
Nrk	Nik related kinase	0.014
Smn1	survival motor neuron 1	0.014
Myh10	myosin, heavy polypeptide 10, non-muscle	0.014
Tbx1	T-box 1	0.014
Dnm1	dynamin 1	0.014
Lhx3	LIM homeobox protein 3	0.014
Nkx2-6	NK2 transcription factor related, locus 6 (Drosophila)	0.014	Mouse
Cenpj	centromere protein J	0.014
Rb1	retinoblastoma 1	0.014
Wnt6	wingless-related MMTV integration site 6	0.014
Evx2	even skipped homeotic gene 2 homolog	0.014
Prkcb	protein kinase C, beta	0.013
Myl3	myosin, light polypeptide 3	0.013
Pthlh	parathyroid hormone-like peptide	0.013
Barx1	BarH-like homeobox 1	0.013
Fshb	follicle stimulating hormone beta	0.013
Skil	SKI-like	0.013
Btbd17	BTB (POZ) domain containing 17	0.013
Ap1s2	adaptor-related protein complex 1, sigma 2 subunit	0.013
Akp3	alkaline phosphatase 3, intestine, not Mn requiring	0.013
Hba-x	hemoglobin X, alpha-like embryonic chain in Hba complex	0.013
Rpl4	ribosomal protein L4	0.013
Lmx1b	LIM homeobox transcription factor 1 beta	0.012
Gltp	glycolipid transfer protein	0.012
Hoxa5	homeobox A5	0.012
Whrn	whirlin	0.012
Wdr1	WD repeat domain 1	0.012
Chrd	chordin	0.012
Runx1t1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	0.012
Sox9	SRY-box containing gene 9	0.012
Tal2	T-cell acute lymphocytic leukemia 2	0.012	Mouse
Lmo2	LIM domain only 2	0.012
Tll2	tolloid-like 2	0.012
Esx1	extraembryonic, spermatogenesis, homeobox 1	0.012
Mobp	myelin-associated oligodendrocytic basic protein	0.012
Nhlh2	nescient helix loop helix 2	0.012	Mouse
Zfpm2	zinc finger protein, multitype 2	0.012
Atp11c	ATPase, class VI, type 11C	0.012
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.012
Ep300	E1A binding protein p300	0.012
Rpl7	ribosomal protein L7	0.012
Ighmbp2	immunoglobulin mu binding protein 2	0.011
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.011
Rprm	reprimo, TP53 dependent G2 arrest mediator candidate	0.011
Kcnk3	potassium channel, subfamily K, member 3	0.011
Hoxd3	homeobox D3	0.011
Kcnj5	potassium inwardly-rectifying channel, subfamily J, member 5	0.011
Osr1	odd-skipped related 1 (Drosophila)	0.011
Capzb	capping protein (actin filament) muscle Z-line, beta	0.011
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.011
Snai1	snail homolog 1 (Drosophila)	0.011
Mn1	meningioma 1	0.011
Rps6ka5	ribosomal protein S6 kinase, polypeptide 5	0.011	Mouse
Zic2	zinc finger protein of the cerebellum 2	0.011
Cdh23	cadherin 23 (otocadherin)	0.011
Shox2	short stature homeobox 2	0.010
Sox11	SRY-box containing gene 11	0.010
Cdx2	caudal type homeobox 2	0.010
Ptf1a	pancreas specific transcription factor, 1a	0.010	Mouse
Gipc3	GIPC PDZ domain containing family, member 3	0.010
Gip	gastric inhibitory polypeptide	0.010
Med1	mediator complex subunit 1	0.010
Mdfi	MyoD family inhibitor	0.010