IMP
Process View
macrophage activation involved in immune response
A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
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Click on a gene's description to view its network relationships with genes known to be involved in "macrophage activation involved in immune response"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Tlr4 | toll-like receptor 4 | 0.465 | ||
| Ccr2 | chemokine (C-C motif) receptor 2 | 0.161 | Mouse | |
| Ldb3 | LIM domain binding 3 | 0.121 | ||
| Ccl2 | chemokine (C-C motif) ligand 2 | 0.116 | ||
| Ccr5 | chemokine (C-C motif) receptor 5 | 0.110 | Mouse | |
| Myd88 | myeloid differentiation primary response gene 88 | 0.101 | ||
| Cd44 | CD44 antigen | 0.101 | ||
| Xcr1 | chemokine (C motif) receptor 1 | 0.061 | Mouse | |
| Ikzf1 | IKAROS family zinc finger 1 | 0.060 | ||
| Ifng | interferon gamma | 0.055 | ||
| Cd22 | CD22 antigen | 0.051 | ||
| Cd14 | CD14 antigen | 0.046 | ||
| Lta | lymphotoxin A | 0.040 | ||
| Ccl3 | chemokine (C-C motif) ligand 3 | 0.039 | ||
| Tlr2 | toll-like receptor 2 | 0.036 | ||
| Cd247 | CD247 antigen | 0.036 | ||
| Mmp9 | matrix metallopeptidase 9 | 0.034 | ||
| Ccr1 | chemokine (C-C motif) receptor 1 | 0.033 | Mouse | |
| Cd7 | CD7 antigen | 0.030 | ||
| Klrk1 | killer cell lectin-like receptor subfamily K, member 1 | 0.030 | ||
| Prdm1 | PR domain containing 1, with ZNF domain | 0.029 | ||
| Map3k14 | mitogen-activated protein kinase kinase kinase 14 | 0.025 | ||
| Tnfsf14 | tumor necrosis factor (ligand) superfamily, member 14 | 0.024 | ||
| Cd19 | CD19 antigen | 0.024 | ||
| Il10 | interleukin 10 | 0.022 | ||
| Csf1 | colony stimulating factor 1 (macrophage) | 0.022 | ||
| Fasl | Fas ligand (TNF superfamily, member 6) | 0.022 | ||
| Il27ra | interleukin 27 receptor, alpha | 0.021 | ||
| Lyz2 | lysozyme 2 | 0.020 | ||
| Ccr6 | chemokine (C-C motif) receptor 6 | 0.019 | Mouse | |
| Selp | selectin, platelet | 0.018 | ||
| Cd4 | CD4 antigen | 0.018 | ||
| Blk | B lymphoid kinase | 0.017 | ||
| Klrd1 | killer cell lectin-like receptor, subfamily D, member 1 | 0.017 | ||
| Tnfrsf1a | tumor necrosis factor receptor superfamily, member 1a | 0.017 | ||
| Tnfrsf9 | tumor necrosis factor receptor superfamily, member 9 | 0.016 | ||
| Actn2 | actinin alpha 2 | 0.015 | ||
| Cxcl13 | chemokine (C-X-C motif) ligand 13 | 0.015 | ||
| Apoe | apolipoprotein E | 0.015 | ||
| Il18rap | interleukin 18 receptor accessory protein | 0.014 | ||
| Fcrla | Fc receptor-like A | 0.014 | ||
| Itk | IL2-inducible T-cell kinase | 0.014 | ||
| Il1r1 | interleukin 1 receptor, type I | 0.013 | ||
| Hcst | hematopoietic cell signal transducer | 0.013 | ||
| Icos | inducible T-cell co-stimulator | 0.012 | ||
| Tnf | tumor necrosis factor | 0.012 | ||
| Cd180 | CD180 antigen | 0.012 | ||
| Cxcr2 | chemokine (C-X-C motif) receptor 2 | 0.012 | Mouse | |
| Tnfrsf1b | tumor necrosis factor receptor superfamily, member 1b | 0.012 | ||
| Prkce | protein kinase C, epsilon | 0.012 | ||
| Cebpb | CCAAT/enhancer binding protein (C/EBP), beta | 0.012 | ||
| Cd3e | CD3 antigen, epsilon polypeptide | 0.012 | ||
| Src | Rous sarcoma oncogene | 0.012 | ||
| S1pr4 | sphingosine-1-phosphate receptor 4 | 0.011 | ||
| Gzmb | granzyme B | 0.011 | ||
| Ncr1 | natural cytotoxicity triggering receptor 1 | 0.011 | ||
| Cxcr3 | chemokine (C-X-C motif) receptor 3 | 0.011 | Mouse | |
| Gpr132 | G protein-coupled receptor 132 | 0.011 | ||
| Itgax | integrin alpha X | 0.011 | ||
| Il12rb2 | interleukin 12 receptor, beta 2 | 0.010 | ||
| Lair1 | leukocyte-associated Ig-like receptor 1 | 0.010 | ||
| Ltb | lymphotoxin B | 0.010 | ||
| Cd96 | CD96 antigen | 0.010 | ||
| H2-Ob | histocompatibility 2, O region beta locus | 0.010 |