IMP

Process View

Mus musculus

3 genes annotated in mouse

regulation of definitive erythrocyte differentiation

Any process that modulates the rate, frequency, or extent of definitive erythrocyte differentiation. Definitive erythrocyte differentiation occurs as part of the process of definitive hemopoiesis.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of definitive erythrocyte differentiation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of definitive erythrocyte differentiation" (in gray)

Name	Description	Probability	Func Analog Organism
Gata4	GATA binding protein 4	0.992	Mouse
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.966
Gata6	GATA binding protein 6	0.943	Mouse
Rxra	retinoid X receptor alpha	0.797
Zfpm2	zinc finger protein, multitype 2	0.714
Pitx2	paired-like homeodomain transcription factor 2	0.531
Jag1	jagged 1	0.452
Hoxa1	homeobox A1	0.244
Hand2	heart and neural crest derivatives expressed transcript 2	0.221
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.189
Tbx3	T-box 3	0.167
Tal1	T-cell acute lymphocytic leukemia 1	0.154
Ppara	peroxisome proliferator activated receptor alpha	0.135
Fgf8	fibroblast growth factor 8	0.102
Tgfb2	transforming growth factor, beta 2	0.089
Klf3	Kruppel-like factor 3 (basic)	0.087
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.082
Smad6	MAD homolog 6 (Drosophila)	0.081
Cited2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.073
Vegfa	vascular endothelial growth factor A	0.070
Chd7	chromodomain helicase DNA binding protein 7	0.067
Gata5	GATA binding protein 5	0.061	Mouse
Wt1	Wilms tumor 1 homolog	0.052
Tbx1	T-box 1	0.052
Pax3	paired box gene 3	0.050
Mesp1	mesoderm posterior 1	0.049
Pax2	paired box gene 2	0.048
Kcnq1	potassium voltage-gated channel, subfamily Q, member 1	0.046
Notch1	Notch gene homolog 1 (Drosophila)	0.044
Isl1	ISL1 transcription factor, LIM/homeodomain	0.044
Sox4	SRY-box containing gene 4	0.042
Bmp4	bone morphogenetic protein 4	0.041
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.035
Hand1	heart and neural crest derivatives expressed transcript 1	0.032
Ntf3	neurotrophin 3	0.030
Epor	erythropoietin receptor	0.030
Epha1	Eph receptor A1	0.029
Slc34a2	solute carrier family 34 (sodium phosphate), member 2	0.027
Klf1	Kruppel-like factor 1 (erythroid)	0.027
Foxf1a	forkhead box F1a	0.027
P2rx1	purinergic receptor P2X, ligand-gated ion channel, 1	0.025
Scn5a	sodium channel, voltage-gated, type V, alpha	0.024
Gpr97	G protein-coupled receptor 97	0.023
Myl7	myosin, light polypeptide 7, regulatory	0.023
Myb	myeloblastosis oncogene	0.023
Gfi1b	growth factor independent 1B	0.022
S1pr2	sphingosine-1-phosphate receptor 2	0.022
Tbx2	T-box 2	0.022
Dll1	delta-like 1 (Drosophila)	0.022
Srrm4	serine/arginine repetitive matrix 4	0.021
Tead3	TEA domain family member 3	0.021
Eya1	eyes absent 1 homolog (Drosophila)	0.021
Sox9	SRY-box containing gene 9	0.020
Foxc2	forkhead box C2	0.019
Sox7	SRY-box containing gene 7	0.019
Hey1	hairy/enhancer-of-split related with YRPW motif 1	0.019
Fgfr2	fibroblast growth factor receptor 2	0.018
Lef1	lymphoid enhancer binding factor 1	0.018
Bnc1	basonuclin 1	0.018
Tbxa2r	thromboxane A2 receptor	0.018
Hoxb4	homeobox B4	0.018
Ank1	ankyrin 1, erythroid	0.017
Tbx20	T-box 20	0.017
Efnb1	ephrin B1	0.017
Muc13	mucin 13, epithelial transmembrane	0.016
Shh	sonic hedgehog	0.016
Axin2	axin2	0.016
Acvr1	activin A receptor, type 1	0.015
Gfi1	growth factor independent 1	0.015
Espn	espin	0.014
Nos3	nitric oxide synthase 3, endothelial cell	0.014
Hhex	hematopoietically expressed homeobox	0.014
Slc4a1	solute carrier family 4 (anion exchanger), member 1	0.014
Mybpc3	myosin binding protein C, cardiac	0.013
Snai1	snail homolog 1 (Drosophila)	0.013
Lmx1a	LIM homeobox transcription factor 1 alpha	0.012
Slc6a4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	0.012
Plac1	placental specific protein 1	0.012
Myo6	myosin VI	0.012
Mta2	metastasis-associated gene family, member 2	0.012
Mta1	metastasis associated 1	0.012
Sema6d	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	0.012
Kpna1	karyopherin (importin) alpha 1	0.012
Rara	retinoic acid receptor, alpha	0.012
Tcf21	transcription factor 21	0.012
Foxg1	forkhead box G1	0.011
Atoh8	atonal homolog 8 (Drosophila)	0.011
Zfp768	zinc finger protein 768	0.011
Fgf10	fibroblast growth factor 10	0.011
Foxa3	forkhead box A3	0.011
Prdm6	PR domain containing 6	0.011
Sct	secretin	0.011
Cyp19a1	cytochrome P450, family 19, subfamily a, polypeptide 1	0.011
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.011
Efnb2	ephrin B2	0.011
Smad3	MAD homolog 3 (Drosophila)	0.011
Epha3	Eph receptor A3	0.011
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.011
Qrich1	glutamine-rich 1	0.010
Hoxa3	homeobox A3	0.010
Cmtm8	CKLF-like MARVEL transmembrane domain containing 8	0.010
Hoxb5	homeobox B5	0.010
Mark4	MAP/microtubule affinity-regulating kinase 4	0.010
Lat	linker for activation of T cells	0.010
F2rl3	coagulation factor II (thrombin) receptor-like 3	0.010
Runx1	runt related transcription factor 1	0.010
Apoa1	apolipoprotein A-I	0.010