IMP

Process View

Rattus norvegicus

15 genes annotated in rat

regulation of innate immune response

Any process that modulates the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in rat Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of innate immune response"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of innate immune response" (in gray)

Name	Description	Probability	Func Analog Organism
RT1-EC2	RT1 class Ib, locus EC2	0.298
Klrd1	killer cell lectin-like receptor, subfamily D, member 1	0.157
Mmp12	matrix metallopeptidase 12	0.106
Zfp36	zinc finger protein 36	0.102
Ccr2	chemokine (C-C motif) receptor 2	0.058
Cp	ceruloplasmin	0.052
Cfb	complement factor B	0.052
Cd38	CD38 molecule	0.052
Psmb9	proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)	0.048
Serpina3n	serine (or cysteine) peptidase inhibitor, clade A, member 3N	0.046
Il1b	interleukin 1 beta	0.045
Igsf6	immunoglobulin superfamily, member 6	0.044
Klrb1a	killer cell lectin-like receptor subfamily B, member 1A	0.044	Mouse
Apol3	apolipoprotein L, 3	0.039
RT1-S3	RT1 class Ib, locus S3	0.034	Rat
Cd247	Cd247 molecule	0.033
Serping1	serine (or cysteine) peptidase inhibitor, clade G, member 1	0.032	Human
Nfya	nuclear transcription factor-Y alpha	0.032
Ifng	interferon gamma	0.031
Gzmk	granzyme K	0.029
Mmp8	matrix metallopeptidase 8	0.028
Lilrb4	leukocyte immunoglobulin-like receptor, subfamily B, member 4	0.028
Cd2	Cd2 molecule	0.028
Lcn2	lipocalin 2	0.025
Gzmb	granzyme B	0.024
Il8rb	interleukin 8 receptor, beta	0.024
Nras	neuroblastoma ras oncogene	0.024
Arhgap15	Rho GTPase activating protein 15	0.023
LOC300024	similar to Ly6-B antigen gene	0.023
Calcrl	calcitonin receptor-like	0.022
Batf3	basic leucine zipper transcription factor, ATF-like 3	0.022
Sell	selectin L	0.022
Amd1	adenosylmethionine decarboxylase 1	0.022
Gimap4	GTPase, IMAP family member 4	0.021
LOC24906	RoBo-1	0.021
Lig3	ligase III, DNA, ATP-dependent	0.021
Csf1	colony stimulating factor 1 (macrophage)	0.021
Ptafr	platelet-activating factor receptor	0.020	Mouse
Arl11	ADP-ribosylation factor-like 11	0.020
C1r	complement component 1, r subcomponent	0.020
LOC100363783	rCG53773-like	0.020
Myo1f	myosin IF	0.019
Ptger2	prostaglandin E receptor 2 (subtype EP2)	0.019
C1s	complement component 1, s subcomponent	0.019
Lzts2	leucine zipper, putative tumor suppressor 2	0.018
Gcnt1	glucosaminyl (N-acetyl) transferase 1, core 2 (beta-1,6-N-acetylglucosaminyltransferase)	0.018
Icam1	intercellular adhesion molecule 1	0.018
Pdlim2	PDZ and LIM domain 2	0.018
Blnk	B-cell linker	0.018
Cd69	Cd69 molecule	0.018	Rat
Cd5	Cd5 molecule	0.017
Il7r	interleukin 7 receptor	0.016
Csf3r	colony stimulating factor 3 receptor (granulocyte)	0.016
C7	complement component 7	0.016
Myh9	myosin, heavy chain 9, non-muscle	0.016
Nkg7	natural killer cell group 7 sequence	0.016
Lpl	lipoprotein lipase	0.016
Ccl4	chemokine (C-C motif) ligand 4	0.016
Casp8	caspase 8	0.016
Lilrb3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	0.016
Hlx	H2.0-like homeobox	0.015
Clec7a	C-type lectin domain family 7, member a	0.015	Human Rat
Phemx	pan hematopoietic expression	0.015
Prf1	perforin 1 (pore forming protein)	0.015
Serbp1	Serpine1 mRNA binding protein 1	0.015
Mcpt8	mast cell protease 8	0.015
Mmp7	matrix metallopeptidase 7	0.014
Lck	lymphocyte-specific protein tyrosine kinase	0.014
Lyn	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.014	Mouse
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.014
Parvg	parvin, gamma	0.014
Rab13	RAB13, member RAS oncogene family	0.014
Gstm3	glutathione S-transferase mu 3	0.014
LOC100364212	heterogeneous nuclear ribonucleoprotein K-like	0.014
Atp2a3	ATPase, Ca++ transporting, ubiquitous	0.014
Tlr4	toll-like receptor 4	0.014
Jak1	Janus kinase 1	0.013
Fbxo32	F-box protein 32	0.013
Ctla2a	cytotoxic T lymphocyte-associated protein 2 alpha	0.013
Olr837	olfactory receptor 837	0.013
Oas1i	2 ' -5 ' oligoadenylate synthetase 1I	0.013
Cd48	Cd48 molecule	0.012
Pou2af1	POU class 2 associating factor 1	0.012
Crtap	cartilage associated protein	0.012
Tcf12	transcription factor 12	0.012
Odf3	outer dense fiber of sperm tails 3	0.012
Plg	plasminogen	0.012
Phkg1	phosphorylase kinase, gamma 1	0.012
Ptpn22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.012
Unc93b1	unc-93 homolog B1 (C. elegans)	0.012
Kynu	kynureninase (L-kynurenine hydrolase)	0.012
RGD1305793	similar to hypothetical protein FLJ20154	0.012
Adar	adenosine deaminase, RNA-specific	0.012
Fabp4	fatty acid binding protein 4, adipocyte	0.012
Smad1	SMAD family member 1	0.012
Oas1a	2'-5' oligoadenylate synthetase 1A	0.012
Mca32	mast cell antigen 32	0.011
Sirpa	signal-regulatory protein alpha	0.011
Serpinb3	serine protease inhibitor B3	0.011
Sept1	septin 1	0.011
RT1-M3-1	RT1 class Ib, locus M3, gene 1	0.011	Rat
Irak3	interleukin-1 receptor-associated kinase 3	0.011
Nfkbid	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta	0.011
Adam7	ADAM metallopeptidase domain 7	0.011
Pcsk7	proprotein convertase subtilisin/kexin type 7	0.011
Hyal2	hyaluronoglucosaminidase 2	0.011
Nek9	NIMA (never in mitosis gene a)- related kinase 9	0.011
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.011
Oas1b	2-5 oligoadenylate synthetase 1B	0.010
Cd8a	CD8a molecule	0.010
Klra22	killer cell lectin-like receptor subfamily A, member 22	0.010	Rat
Klra17	killer cell lectin-like receptor, subfamily A, member 17	0.010
Ceacam10	carcinoembryonic antigen-related cell adhesion molecule 10	0.010
Ubd	ubiquitin D	0.010
Rps27	ribosomal protein S27	0.010
RT1-N3	RT1 class Ib, locus N3	0.010	Rat
Kcna3	potassium voltage-gated channel, shaker-related subfamily, member 3	0.010
Uba7	ubiquitin-like modifier activating enzyme 7	0.010
Lypd3	Ly6/Plaur domain containing 3	0.010