IMP

Process View

Rattus norvegicus

1 genes annotated in rat

exogenous drug catabolic process

The chemical reactions and pathways resulting in the breakdown of a drug that has originated externally to the cell or organism.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in rat Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "exogenous drug catabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "exogenous drug catabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
Cyp2b1	cytochrome P450, family 2, subfamily b, polypeptide 1	0.996	Human
Cyp3a18	cytochrome P450, family 3, subfamily a, polypeptide 18	0.894	Human
Cyp2c13	cytochrome P450, family 2, subfamily c, polypeptide 13	0.869
Apob	apolipoprotein B	0.850
LOC293989	cytochrome P450-like	0.831
Ugt2b	UDP glycosyltransferase 2 family, polypeptide B	0.789
Cyp2a1	cytochrome P450, family 2, subfamily a, polypeptide 1	0.756
Cyp2d4	cytochrome P450, family 2, subfamily d, polypeptide 4	0.756
Cyp1a1	cytochrome P450, family 1, subfamily a, polypeptide 1	0.736
Cyp2c11	cytochrome P450, subfamily 2, polypeptide 11	0.714	Human
Ugt2b1	UDP glucuronosyltransferase 2 family, polypeptide B1	0.705
Cyp4a10	cytochrome P450, family 4, subfamily a, polypeptide 10	0.704
Abcb11	ATP-binding cassette, subfamily B (MDR/TAP), member 11	0.600
Sult1e1	sulfotransferase family 1E, estrogen-preferring, member 1	0.589
Sult1b1	sulfotransferase family, cytosolic, 1B, member 1	0.579
LOC494499	LOC494499 protein	0.493
Cyp2e1	cytochrome P450, family 2, subfamily e, polypeptide 1	0.484
Cyp2d3	cytochrome P450, family 2, subfamily d, polypeptide 3	0.484
Ugt2b5	UDP glucuronosyltransferase 2 family, polypeptide B5	0.453
Cyp4f1	cytochrome P450, family 4, subfamily f, polypeptide 1	0.448	Rat
Crygf	crystallin, gamma F	0.437
Mettl7b	methyltransferase like 7B	0.398
Sult1c2	sulfotransferase family, cytosolic, 1C, member 2	0.385
LOC100365112	carboxylesterase-like	0.340
Cyp2b3	cytochrome P450, family 2, subfamily b, polypeptide 3	0.339
Cyp2c23	cytochrome P450, family 2, subfamily c, polypeptide 23	0.303
Cyp2a2	cytochrome P450, family 2, subfamily a, polypeptide 2	0.292
Nat8	N-acetyltransferase 8	0.273
Cyp3a2	cytochrome P450, family 3, subfamily a, polypeptide 2	0.261	Human
Cyp1a2	cytochrome P450, family 1, subfamily a, polypeptide 2	0.250
Cyp7a1	cytochrome P450, family 7, subfamily a, polypeptide 1	0.231
Akr1c18	aldo-keto reductase family 1, member C18	0.199
Fabp1	fatty acid binding protein 1, liver	0.182
Slco1a4	solute carrier organic anion transporter family, member 1a4	0.182
Cyp4f4	cytochrome P450, family 4, subfamily f, polypeptide 4	0.178	Rat
Otc	ornithine carbamoyltransferase	0.160
Abcc6	ATP-binding cassette, subfamily C (CFTR/MRP), member 6	0.159
Cyp2d2	cytochrome P450, family 2, subfamily d, polypeptide 2	0.147
Cyp2c7	cytochrome P450, family 2, subfamily c, polypeptide 7	0.140
Rup2	urinary protein 2	0.139
Slc23a1	solute carrier family 23 (nucleobase transporters), member 1	0.133
Cyp4a2	cytochrome P450, family 4, subfamily a, polypeptide 2	0.129	Rat
Cyp2c22	cytochrome P450, family 2, subfamily c, polypeptide 22	0.124
LOC100361547	Cytochrome P450, family 2, subfamily c, polypeptide 7-like	0.121
Ces1f	carboxylesterase 1F	0.113
Tdo2	tryptophan 2,3-dioxygenase	0.110
Sult1c3	sulfotransferase family, cytosolic, 1C, member 3	0.105
Cyp2b2	cytochrome P450, family 2, subfamily b, polypeptide 2	0.101	Human
Slco1a1	solute carrier organic anion transporter family, member 1a1	0.099
Serpina3k	serine (or cysteine) peptidase inhibitor, clade A, member 3K	0.088
Ces1e	carboxylesterase 1E	0.087
Gsta2	glutathione S-transferase A2	0.084
Cps1	carbamoyl-phosphate synthetase 1	0.083
Olr59	olfactory receptor 59	0.083
Acot12	acyl-CoA thioesterase 12	0.079
Mosc1	MOCO sulphurase C-terminal domain containing 1	0.076
Azgp1	alpha-2-glycoprotein 1, zinc-binding	0.073
Slc22a7	solute carrier family 22 (organic anion transporter), member 7	0.072
Akr1c12	aldo-keto reductase family 1, member C12	0.072
Dpys	dihydropyrimidinase	0.063
Spink1	serine peptidase inhibitor, Kazal type 1	0.063
Sult2a1	sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1	0.062
Cyp2d1	cytochrome P450, family 2, subfamily d, polypeptide 1	0.054
Ugt2b37	UDP-glucuronosyltransferase 2 family, member 37	0.053
Ces1c	carboxylesterase 1C	0.053
LOC299282	Serine protease inhibitor	0.050
Slco1b3	solute carrier organic anion transporter family, member 1b3	0.049
LOC100361864	UDP-glucuronosyltransferase 2B3-like	0.046
Fdxr	ferredoxin reductase	0.046
Cyp3a23/3a1	cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 1	0.040	Human
Acox2	acyl-Coenzyme A oxidase 2, branched chain	0.039
Olr1701	olfactory receptor 1701	0.039
Ust5r	integral membrane transport protein UST5r	0.038
Dhfr	dihydrofolate reductase	0.038
Selp	selectin P	0.037
Zfp37	zinc finger protein 37	0.036
Si	sucrase-isomaltase (alpha-glucosidase)	0.035
Camkk2	calcium/calmodulin-dependent protein kinase kinase 2, beta	0.034
Pon1	paraoxonase 1	0.033
Pck1	phosphoenolpyruvate carboxykinase 1 (soluble)	0.033
Fmo1	flavin containing monooxygenase 1	0.033
Slc22a1	solute carrier family 22 (organic cation transporter), member 1	0.033
G6pc	glucose-6-phosphatase, catalytic subunit	0.033
Rag1	recombination activating gene 1	0.033
Dmgdh	dimethylglycine dehydrogenase	0.033
Akr1c14	aldo-keto reductase family 1, member C14	0.031
Asgr1	asialoglycoprotein receptor 1	0.031
Adh4	alcohol dehydrogenase 4 (class II), pi polypeptide	0.030
Cdh17	cadherin 17	0.028
A1i3	alpha-1-inhibitor III	0.028
Pfkfb1	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1	0.027
Mbl2	mannose-binding lectin (protein C) 2	0.027
Apoa5	apolipoprotein A-V	0.026
Ppara	peroxisome proliferator activated receptor alpha	0.026
Hsd3b5	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5	0.025
Ugt2b7	UDP glucuronosyltransferase 2 family, polypeptide B7	0.025
Akr1c1	aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)	0.025
Dpep1	dipeptidase 1 (renal)	0.025
Adh7	alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide	0.024
Tas2r118	taste receptor, type 2, member 118	0.024
Ugt2b36	UDP glucuronosyltransferase 2 family, polypeptide B36	0.024
Qpct	glutaminyl-peptide cyclotransferase	0.024
Adh1	alcohol dehydrogenase 1 (class I)	0.023
Gnmt	glycine N-methyltransferase	0.023
Cyp3a9	cytochrome P450, family 3, subfamily a, polypeptide 9	0.022	Human
Gja5	gap junction protein, alpha 5	0.022
Abcc2	ATP-binding cassette, subfamily C (CFTR/MRP), member 2	0.021
Ces2c	carboxylesterase 2C	0.020
Igfals	insulin-like growth factor binding protein, acid labile subunit	0.020
F9	coagulation factor IX	0.020
Hnf4a	hepatocyte nuclear factor 4, alpha	0.019
Ugt2a1	UDP glucuronosyltransferase 2 family, polypeptide A1	0.019
Tat	tyrosine aminotransferase	0.019
Cyp17a1	cytochrome P450, family 17, subfamily a, polypeptide 1	0.019
Dpyd	dihydropyrimidine dehydrogenase	0.019
Aqp9	aquaporin 9	0.019
Cdh8	cadherin 8	0.018
Rxrg	retinoid X receptor gamma	0.018
Prl8a4	prolactin family 8, subfamily a, member 4	0.018
Il1rap	interleukin 1 receptor accessory protein	0.018
Nr0b2	nuclear receptor subfamily 0, group B, member 2	0.017
Pbsn	probasin	0.017
Serpina3m	serine (or cysteine) proteinase inhibitor, clade A, member 3M	0.017
Galnt5	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)	0.017
LOC691759	hypothetical protein LOC691759	0.017
Cyss	cystatin S	0.017
Dao	D-amino-acid oxidase	0.016
Sult1a1	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1	0.016
L3mbtl3	l(3)mbt-like 3 (Drosophila)	0.016
Fgfr4	fibroblast growth factor receptor 4	0.016
Mug1	murinoglobulin 1	0.016
Cyp2j4	cytochrome P450, family 2, subfamily j, polypeptide 4	0.016
Gck	glucokinase	0.015
Serpina5	serine (or cysteine) peptidase inhibitor, clade A, member 5	0.015
C8b	complement component 8, beta polypeptide	0.015
Il1a	interleukin 1 alpha	0.015
Crisp1	cysteine-rich secretory protein 1	0.015
Dnase1	deoxyribonuclease I	0.015
Cyp27b1	cytochrome P450, family 27, subfamily b, polypeptide 1	0.015
Kcnd3	potassium voltage-gated channel, Shal-related subfamily, member 3	0.014
Fgb	fibrinogen beta chain	0.014
Afm	afamin	0.014
Pigr	polymeric immunoglobulin receptor	0.014
Cyp2f4	cytochrome P450, family 2, subfamily f, polypeptide 4	0.014
Sult2al1	sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring-like 1	0.014
Igfbp1	insulin-like growth factor binding protein 1	0.014
Opn1mw	opsin 1 (cone pigments), medium-wave-sensitive	0.013
Kynu	kynureninase (L-kynurenine hydrolase)	0.013
Adamtsl4	ADAMTS-like 4	0.013
Nr1i3	nuclear receptor subfamily 1, group I, member 3	0.013
Il8ra	interleukin 8 receptor, alpha	0.013
Keg1	kidney expressed gene 1	0.013
Cyp11a1	cytochrome P450, family 11, subfamily a, polypeptide 1	0.013
Vcsa1	variable coding sequence A1	0.013
Pou2f3	POU class 2 homeobox 3	0.013
Efcab4a	EF-hand calcium binding domain 4A	0.013
Acaa1b	acetyl-Coenzyme A acyltransferase 1B	0.012
RGD1306474	similar to RIKEN cDNA 9530003J23	0.012
Adhfe1	alcohol dehydrogenase, iron containing, 1	0.012
Tpbpa	trophoblast specific protein alpha	0.012
Svs3a	seminal vesicle secretory protein 3A	0.012
Dio1	deiodinase, iodothyronine, type I	0.012
Acsm2	acyl-CoA synthetase medium-chain family member 2	0.012
Cyp2c12	cytochrome P450, family 2, subfamily c, polypeptide 12	0.012
Hsd17b6	hydroxysteroid (17-beta) dehydrogenase 6	0.011
Aldob	aldolase B, fructose-bisphosphate	0.011
Hrg	histidine-rich glycoprotein	0.011
Hnmt	histamine N-methyltransferase	0.011
Crybb1	crystallin, beta B1	0.011
Apcs	amyloid P component, serum	0.010
Fabp7	fatty acid binding protein 7, brain	0.010
Vom1r101	vomeronasal 1 receptor 101	0.010
Apoa4	apolipoprotein A-IV	0.010
Cyp2j3	cytochrome P450, family 2, subfamily j, polypeptide 3	0.010
Il15	interleukin 15	0.010
Olr1654	olfactory receptor 1654	0.010
LOC259244	alpha-2u globulin PGCL3	0.010
Inhbe	inhibin beta E	0.010