IMP

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Rattus norvegicus

16 genes annotated in rat

cell activation involved in immune response

A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.

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Known genes in the process in rat Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cell activation involved in immune response"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "cell activation involved in immune response" (in gray)

Name	Description	Probability	Func Analog Organism
Hck	hemopoietic cell kinase	0.344	Rat
Cd53	Cd53 molecule	0.279
Il2rb	interleukin 2 receptor, beta	0.212
Ywhag	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.209	Rat
Lyn	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.209
Cd4	Cd4 molecule	0.180
Cd38	CD38 molecule	0.168
Sirpa	signal-regulatory protein alpha	0.163
Ptprc	protein tyrosine phosphatase, receptor type, C	0.147	Mouse
Cybb	cytochrome b-245, beta polypeptide	0.145
Ptafr	platelet-activating factor receptor	0.133
Csf2rb	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.110
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.109
Csf1	colony stimulating factor 1 (macrophage)	0.108
Actr3	ARP3 actin-related protein 3 homolog (yeast)	0.096
Ripk3	receptor-interacting serine-threonine kinase 3	0.091
Tgfbr2	transforming growth factor, beta receptor II	0.083
Itpr2	inositol 1,4,5-triphosphate receptor, type 2	0.082
St8sia4	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4	0.079
Dock8	dedicator of cytokinesis 8	0.078
Il2rg	interleukin 2 receptor, gamma	0.077
Vav1	vav 1 guanine nucleotide exchange factor	0.076
Plau	plasminogen activator, urokinase	0.076
Bin2	bridging integrator 2	0.075
Ptpn18	protein tyrosine phosphatase, non-receptor type 18	0.073
Casp1	caspase 1	0.069
Ywhae	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.069	Rat
Inpp5d	inositol polyphosphate-5-phosphatase D	0.064
Arl11	ADP-ribosylation factor-like 11	0.064
Ctse	cathepsin E	0.062
Cd247	Cd247 molecule	0.062
P2ry6	pyrimidinergic receptor P2Y, G-protein coupled, 6	0.054
Ppp2ca	protein phosphatase 2, catalytic subunit, alpha isoform	0.053
Prf1	perforin 1 (pore forming protein)	0.053
Ccr5	chemokine (C-C motif) receptor 5	0.049
Morf4l2	mortality factor 4 like 2	0.049
Ciita	class II, major histocompatibility complex, transactivator	0.048
Myo1f	myosin IF	0.047
Arhgap4	Rho GTPase activating protein 4	0.047
Rassf5	Ras association (RalGDS/AF-6) domain family member 5	0.046
Clec4a3	C-type lectin domain family 4, member a3	0.046
Acap1	ArfGAP with coiled-coil, ankyrin repeat and PH domains 1	0.045
Atp6ap1	ATPase, H+ transporting, lysosomal accessory protein 1	0.045
Wdr1	WD repeat domain 1	0.045
Cmklr1	chemokine-like receptor 1	0.042
Lcp2	lymphocyte cytosolic protein 2	0.041
Plcg2	phospholipase C, gamma 2	0.041	Mouse
Psd4	pleckstrin and Sec7 domain containing 4	0.037
Soat1	sterol O-acyltransferase 1	0.036
Igsf6	immunoglobulin superfamily, member 6	0.036
Icam1	intercellular adhesion molecule 1	0.035
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.035
Itgb2	integrin, beta 2	0.035
Cd86	CD86 molecule	0.035
Icos	inducible T-cell co-stimulator	0.034
Sell	selectin L	0.033
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.032	Rat
Pitpna	phosphatidylinositol transfer protein, alpha	0.032
Rhoh	ras homolog gene family, member H	0.031
Arrdc1	arrestin domain containing 1	0.031
Calm1	calmodulin 1	0.031
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.031
Irf5	interferon regulatory factor 5	0.030
Gzmk	granzyme K	0.030
Cd8b	CD8b molecule	0.030
Il17ra	interleukin 17 receptor A	0.029
Arhgap9	Rho GTPase activating protein 9	0.029
Faslg	Fas ligand (TNF superfamily, member 6)	0.028
Pfkfb2	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2	0.027
Tlr4	toll-like receptor 4	0.027	Mouse
Ptger2	prostaglandin E receptor 2 (subtype EP2)	0.026
Arhgap25	Rho GTPase activating protein 25	0.026
Cd3g	CD3 molecule, gamma	0.026
Klhl6	kelch-like 6 (Drosophila)	0.026
Tbxas1	thromboxane A synthase 1, platelet	0.025
Mov10	Moloney leukemia virus 10	0.025
Lypd3	Ly6/Plaur domain containing 3	0.025
Laptm5	lysosomal protein transmembrane 5	0.025
Epor	erythropoietin receptor	0.024
Cd37	CD37 molecule	0.024
Pik3cd	phosphoinositide-3-kinase, catalytic, delta polypeptide	0.024
Cyp2s1	cytochrome P450, family 2, subfamily s, polypeptide 1	0.023
Cxcr3	chemokine (C-X-C motif) receptor 3	0.023
Acrv1	acrosomal vesicle protein 1	0.023
Ctsc	cathepsin C	0.023
Mpeg1	macrophage expressed 1	0.023
Ywhah	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.023	Rat
Havcr1	hepatitis A virus cellular receptor 1	0.023
Mutyh	mutY homolog (E. coli)	0.023
Hrh2	histamine receptor H 2	0.022
Dok2	docking protein 2	0.022
Tgfbr3	transforming growth factor, beta receptor III	0.022
Phox2a	paired-like homeobox 2a	0.021
Klrc1	killer cell lectin-like receptor subfamily C, member 1	0.021
Dchs1	dachsous 1 (Drosophila)	0.021
C5ar1	complement component 5a receptor 1	0.021
Gcnt3	glucosaminyl (N-acetyl) transferase 3, mucin type	0.021
Hsp90aa1	heat shock protein 90, alpha (cytosolic), class A member 1	0.021
Atp6v1a	ATPase, H+ transporting, lysosomal V1 subunit A	0.020
Bdkrb2	bradykinin receptor B2	0.020
Apbb1ip	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein	0.020	Mouse
Klrc2	killer cell lectin-like receptor subfamily C, member 2	0.020
Ncr1	natural cytotoxicity triggering receptor 1	0.019
Pgam1	phosphoglycerate mutase 1 (brain)	0.019
Fgf16	fibroblast growth factor 16	0.019
Il1b	interleukin 1 beta	0.019
N5	DNA binding protein N5	0.019
Lta	lymphotoxin alpha (TNF superfamily, member 1)	0.019
A2m	alpha-2-macroglobulin	0.019
Il9r	interleukin 9 receptor	0.018
Zwint	ZW10 interactor	0.018
Fancc	Fanconi anemia, complementation group C	0.018
Anpep	alanyl (membrane) aminopeptidase	0.018
Ptk2b	PTK2B protein tyrosine kinase 2 beta	0.018	Mouse
Pld1	phospholipase D1	0.018	Rat
Nptn	neuroplastin	0.017
Mmp12	matrix metallopeptidase 12	0.017
Calcr	calcitonin receptor	0.017	Rat
Tnfrsf8	tumor necrosis factor receptor superfamily, member 8	0.017	Rat
Hmha1	histocompatibility (minor) HA-1	0.017
Pla2g4a	phospholipase A2, group IVA (cytosolic, calcium-dependent)	0.017
Creb1	cAMP responsive element binding protein 1	0.016
Bcl2a1d	B-cell leukemia/lymphoma 2 related protein A1d	0.016
Hpgds	hematopoietic prostaglandin D synthase	0.016
Il7r	interleukin 7 receptor	0.016
Slc9a1	solute carrier family 9 (sodium/hydrogen exchanger), member 1	0.016
Stat3	signal transducer and activator of transcription 3	0.016
Il1rl2	interleukin 1 receptor-like 2	0.016
Tuba1c	tubulin, alpha 1C	0.015
Cd68	Cd68 molecule	0.015
Prps1	phosphoribosyl pyrophosphate synthetase 1	0.015
Srxn1	sulfiredoxin 1 homolog (S. cerevisiae)	0.015
Olr1496	olfactory receptor 1496	0.015
Hdac7	histone deacetylase 7	0.015
Atp1b1	ATPase, Na+/K+ transporting, beta 1 polypeptide	0.015
Rhob	ras homolog gene family, member B	0.014
Ncan	neurocan	0.014
Kynu	kynureninase (L-kynurenine hydrolase)	0.014
Scn11a	sodium channel, voltage-gated, type XI, alpha	0.014
Dnaja2	DnaJ (Hsp40) homolog, subfamily A, member 2	0.014
Hcls1	hematopoietic cell specific Lyn substrate 1	0.014
Ucp2	uncoupling protein 2 (mitochondrial, proton carrier)	0.014
Arhgap27	Rho GTPase activating protein 27	0.014
Bak1	BCL2-antagonist/killer 1	0.014
LOC308990	hypothetical protein LOC308990	0.014
RT1-Db1	RT1 class II, locus Db1	0.014
Prkcd	protein kinase C, delta	0.014
P2ry14	purinergic receptor P2Y, G-protein coupled, 14	0.014
Stap1	signal transducing adaptor family member 1	0.013
Fam46a	family with sequence similarity 46, member A	0.013
Syt8	synaptotagmin VIII	0.013
Ptpn6	protein tyrosine phosphatase, non-receptor type 6	0.013
LOC100364854	similar to RIKEN cDNA A430107P09 gene-like	0.013
Cxcr4	chemokine (C-X-C motif) receptor 4	0.013
Fgd4	FYVE, RhoGEF and PH domain containing 4	0.013
Batf3	basic leucine zipper transcription factor, ATF-like 3	0.013
Gfra2	GDNF family receptor alpha 2	0.013
Edn1	endothelin 1	0.013
Cd3d	CD3 molecule, delta	0.013
Pde3a	phosphodiesterase 3A, cGMP inhibited	0.013
Prlhr	prolactin releasing hormone receptor	0.013
Figf	c-fos induced growth factor	0.013
Tnfrsf14	tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)	0.013	Rat
Anxa3	annexin A3	0.013	Human
Nrg2	neuregulin 2	0.013
Ppp2cb	protein phosphatase 2, catalytic subunit, beta isoform	0.013
Ccr3	chemokine (C-C motif) receptor 3	0.012
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.012
Prkcb	protein kinase C, beta	0.012
Ncf4	neutrophil cytosolic factor 4	0.012
Sfrp4	secreted frizzled-related protein 4	0.012
Tap2	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)	0.012
Elf1	E74-like factor 1	0.012
Aspg	asparaginase homolog (S. cerevisiae)	0.012
Casp8	caspase 8	0.012
Serpinb1a	serine (or cysteine) proteinase inhibitor, clade B, member 1a	0.012
Ap2m1	adaptor-related protein complex 2, mu 1 subunit	0.012
Dcc	deleted in colorectal carcinoma	0.012
Klrd1	killer cell lectin-like receptor, subfamily D, member 1	0.012
Lgmn	legumain	0.012
Prnp	prion protein	0.012
Hsbp1	heat shock factor binding protein 1	0.012
Cltc	clathrin, heavy chain (Hc)	0.012
Kcna3	potassium voltage-gated channel, shaker-related subfamily, member 3	0.011
Zbp1	Z-DNA binding protein 1	0.011
Ptpn1	protein tyrosine phosphatase, non-receptor type 1	0.011
Mcpt3	mast cell peptidase 3	0.011
Cacna1a	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	0.011
RGD1559588	similar to cell surface receptor FDFACT	0.011
Vom2r27	vomeronasal 2 receptor, 27	0.011
Fcnb	ficolin B	0.011
Ptpre	protein tyrosine phosphatase, receptor type, E	0.011
Slc18a2	solute carrier family 18 (vesicular monoamine), member 2	0.011
Entpd1	ectonucleoside triphosphate diphosphohydrolase 1	0.011
Triobp	TRIO and F-actin binding protein	0.011
Aqp8	aquaporin 8	0.011
Hsp90b1	heat shock protein 90, beta, member 1	0.011
Mef2d	myocyte enhancer factor 2D	0.011
Actg1	actin, gamma 1	0.011
Gls	glutaminase	0.011
Klrg1	killer cell lectin-like receptor subfamily G, member 1	0.011
Grin2c	glutamate receptor, ionotropic, N-methyl D-aspartate 2C	0.011
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.011
Cpa3	carboxypeptidase A3, mast cell	0.011
Sash3	SAM and SH3 domain containing 3	0.011
Msn	moesin	0.011
Htr7	5-hydroxytryptamine (serotonin) receptor 7	0.011
Fgb	fibrinogen beta chain	0.010
Mcpt2	mast cell protease 2	0.010
Cyp21a1	cytochrome P450, family 21, subfamily a, polypeptide 1	0.010
RGD1306474	similar to RIKEN cDNA 9530003J23	0.010
Nras	neuroblastoma ras oncogene	0.010