IMP

Process View

Rattus norvegicus

4 genes annotated in rat

artery smooth muscle contraction

A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the artery. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The artery is a vessel carrying blood away from the heart.

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Known genes in the process in rat Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "artery smooth muscle contraction"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "artery smooth muscle contraction" (in gray)

Name	Description	Probability	Func Analog Organism
Serpina3k	serine (or cysteine) peptidase inhibitor, clade A, member 3K	0.794	Rat
Ahsg	alpha-2-HS-glycoprotein	0.394
Apoh	apolipoprotein H (beta-2-glycoprotein I)	0.303
Alb	albumin	0.288
Rup2	urinary protein 2	0.211
Cyp4f4	cytochrome P450, family 4, subfamily f, polypeptide 4	0.207
RGD1565859	RGD1565859	0.155
LOC299282	Serine protease inhibitor	0.140	Rat
Agxt2	alanine-glyoxylate aminotransferase 2	0.126
Apoa5	apolipoprotein A-V	0.123
Prss2	protease, serine, 2	0.113
Vdr	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.112
A3galt2	alpha 1,3-galactosyltransferase 2	0.110
Il1rn	interleukin 1 receptor antagonist	0.110
Proc	protein C	0.109
Cga	glycoprotein hormones, alpha polypeptide	0.105
Phkg1	phosphorylase kinase, gamma 1	0.098
Apcs	amyloid P component, serum	0.096
Gucy2f	guanylate cyclase 2F	0.094
Olr1413	olfactory receptor 1413	0.093
Ms4a2	membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)	0.092
Kcnj4	potassium inwardly-rectifying channel, subfamily J, member 4	0.081
Nrg1	neuregulin 1	0.079
Sftpa1	surfactant protein A1	0.077
Tacr2	tachykinin receptor 2	0.073
Cpb1	carboxypeptidase B1 (tissue)	0.069
Esr1	estrogen receptor 1	0.067
Spink1	serine peptidase inhibitor, Kazal type 1	0.064
Rorb	RAR-related orphan receptor B	0.061
Olr416	olfactory receptor 416	0.061
Cyp2a2	cytochrome P450, family 2, subfamily a, polypeptide 2	0.061
Slc10a1	solute carrier family 10 (sodium/bile acid cotransporter family), member 1	0.060
Figf	c-fos induced growth factor	0.059
Smad3	SMAD family member 3	0.056
Syt8	synaptotagmin VIII	0.055
Cxcr5	chemokine (C-X-C motif) receptor 5	0.054
Grin2b	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	0.054
Serpina11	serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11	0.050	Rat
Gng7	guanine nucleotide binding protein (G protein), gamma 7	0.050
Agtr1a	angiotensin II receptor, type 1a	0.050
Fosl1	fos-like antigen 1	0.047
Kcnh7	potassium voltage-gated channel, subfamily H (eag-related), member 7	0.047
Gc	group specific component	0.046
Lif	leukemia inhibitory factor	0.046
Pemt	phosphatidylethanolamine N-methyltransferase	0.045
Serpina3m	serine (or cysteine) proteinase inhibitor, clade A, member 3M	0.043	Rat
Dmgdh	dimethylglycine dehydrogenase	0.043
Adra2c	adrenergic, alpha-2C-, receptor	0.043	Rat
Tnp2	transition protein 2	0.043
Lsm6	LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)	0.042
Csf3	colony stimulating factor 3 (granulocyte)	0.039
Serpina3n	serine (or cysteine) peptidase inhibitor, clade A, member 3N	0.039	Rat
Oprd1	opioid receptor, delta 1	0.039
Ttc36	tetratricopeptide repeat domain 36	0.038
C8b	complement component 8, beta polypeptide	0.038
Cyp3a2	cytochrome P450, family 3, subfamily a, polypeptide 2	0.038
Pla2g5	phospholipase A2, group V	0.038
Abcb11	ATP-binding cassette, subfamily B (MDR/TAP), member 11	0.038
Testin	testin gene	0.038
Apoa2	apolipoprotein A-II	0.038
St8sia3	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3	0.037
Hipk3	homeodomain interacting protein kinase 3	0.036
Serpinb5	serpin peptidase inhibitor, clade B (ovalbumin), member 5	0.036
Azgp1	alpha-2-glycoprotein 1, zinc-binding	0.036
Cyp4f1	cytochrome P450, family 4, subfamily f, polypeptide 1	0.035
Hnmt	histamine N-methyltransferase	0.035
Mchr1	melanin-concentrating hormone receptor 1	0.035
Fgf14	fibroblast growth factor 14	0.034
Pdha2	pyruvate dehydrogenase (lipoamide) alpha 2	0.034
Igfals	insulin-like growth factor binding protein, acid labile subunit	0.033
Pcsk1	proprotein convertase subtilisin/kexin type 1	0.033
Ccr2	chemokine (C-C motif) receptor 2	0.033
Cyp2b12	cytochrome P450, family 2, subfamily b, polypeptide 12	0.033
Igf2	insulin-like growth factor 2	0.031
Gria1	glutamate receptor, ionotropic, AMPA 1	0.030
Pde1b	phosphodiesterase 1B, calmodulin-dependent	0.030
Ngf	nerve growth factor (beta polypeptide)	0.030
Vcsa1	variable coding sequence A1	0.030
Asgr2	asialoglycoprotein receptor 2	0.029
Grm6	glutamate receptor, metabotropic 6	0.029
Gal	galanin prepropeptide	0.028
Necab1	N-terminal EF-hand calcium binding protein 1	0.028
Col10a1	collagen, type X, alpha 1	0.028
Kiss1r	KISS1 receptor	0.028
Kcnab1	potassium voltage-gated channel, shaker-related subfamily, beta member 1	0.027
Gabrg3	gamma-aminobutyric acid (GABA) A receptor, gamma 3	0.027
Odf4	outer dense fiber of sperm tails 4	0.027
Aqp8	aquaporin 8	0.027
Zp1	zona pellucida glycoprotein 1 (sperm receptor)	0.027
Cyp2d3	cytochrome P450, family 2, subfamily d, polypeptide 3	0.026
Bhlha15	basic helix-loop-helix family, member a15	0.026
Foxi2	forkhead box I2	0.026
Sema3a	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	0.026
Cyp2c13	cytochrome P450, family 2, subfamily c, polypeptide 13	0.026
Kynu	kynureninase (L-kynurenine hydrolase)	0.026
Fabp1	fatty acid binding protein 1, liver	0.026
Gjb5	gap junction protein, beta 5	0.026
Smo	smoothened homolog (Drosophila)	0.025
Gabrr1	gamma-aminobutyric acid (GABA) receptor, rho 1	0.025
Afp	alpha-fetoprotein	0.025
Hsd17b1	hydroxysteroid (17-beta) dehydrogenase 1	0.025
Fgfr2	fibroblast growth factor receptor 2	0.024
Slco1b3	solute carrier organic anion transporter family, member 1b3	0.024
Prpg1	proline-rich proteoglycan 1	0.024
C1qtnf6	C1q and tumor necrosis factor related protein 6	0.024
Sycn	syncollin	0.024
Spp2	secreted phosphoprotein 2	0.024
Nos3	nitric oxide synthase 3, endothelial cell	0.024
Cit	citron	0.024
Kcns1	potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1	0.024
Il1r1	interleukin 1 receptor, type I	0.023
Pou5f2	POU domain class 5, transcription factor 2	0.023
Adam5	a disintegrin and metallopeptidase domain 5	0.023
Iapp	islet amyloid polypeptide	0.023
Twist2	twist homolog 2 (Drosophila)	0.023
Itih3	inter-alpha trypsin inhibitor, heavy chain 3	0.023
Masp2	mannan-binding lectin serine peptidase 2	0.023
Klkb1	kallikrein B, plasma 1	0.022
Drd1a	dopamine receptor D1A	0.022
Galr2	galanin receptor 2	0.022
Rbp3	retinol binding protein 3, interstitial	0.022
Adh6a	alcohol dehydrogenase 6A (class V)	0.022
B4galt1	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1	0.022
Il17re	interleukin 17 receptor E	0.022
LOC293989	cytochrome P450-like	0.022
Nr1h4	nuclear receptor subfamily 1, group H, member 4	0.022
Pla2g2a	phospholipase A2, group IIA (platelets, synovial fluid)	0.022
Slc2a13	solute carrier family 2 (facilitated glucose transporter), member 13	0.021
Lbp	lipopolysaccharide binding protein	0.021
Kcnh6	potassium voltage-gated channel, subfamily H (eag-related), member 6	0.021
Prap1	proline-rich acidic protein 1	0.021
Cyss	cystatin S	0.021
Prrx1	paired related homeobox 1	0.021
Ccr3	chemokine (C-C motif) receptor 3	0.021
Cyp21a1	cytochrome P450, family 21, subfamily a, polypeptide 1	0.021
Tat	tyrosine aminotransferase	0.020
Cyp2c12	cytochrome P450, family 2, subfamily c, polypeptide 12	0.020
Mpeg1	macrophage expressed 1	0.019
Nlgn2	neuroligin 2	0.019
Hsd3b5	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5	0.019
Olr1361	olfactory receptor 1361	0.019
Sval1	seminal vesicle antigen-like 1	0.019
Gfra1	GDNF family receptor alpha 1	0.019
Kcna3	potassium voltage-gated channel, shaker-related subfamily, member 3	0.019
RGD1307722	similar to hypothetical protein MGC20700	0.019
Fat3	FAT tumor suppressor homolog 3 (Drosophila)	0.019
Pex5l	peroxisomal biogenesis factor 5-like	0.019
Selp	selectin P	0.019
Il7	interleukin 7	0.018
Hpca	hippocalcin	0.018
Synpo	synaptopodin	0.018
Ltb4r	leukotriene B4 receptor	0.018
Cmtm2a	CKLF-like MARVEL transmembrane domain containing 2A	0.018
Ugt2b37	UDP-glucuronosyltransferase 2 family, member 37	0.018
Tlr4	toll-like receptor 4	0.018
Serpind1	serpin peptidase inhibitor, clade D (heparin cofactor), member 1	0.018
Ptgfr	prostaglandin F receptor	0.018
Nmu	neuromedin U	0.018
Scn5a	sodium channel, voltage-gated, type V, alpha subunit	0.018
Htr2c	5-hydroxytryptamine (serotonin) receptor 2C	0.018
Pnliprp2	pancreatic lipase-related protein 2	0.018
Lrrc56	leucine rich repeat containing 56	0.018
Mmp10	matrix metallopeptidase 10	0.018
Gpr182	G protein-coupled receptor 182	0.018
Cpne9	copine family member IX	0.018
Agxt	alanine-glyoxylate aminotransferase	0.018
Foxe3	forkhead box E3	0.017
Sirpa	signal-regulatory protein alpha	0.017
Cckar	cholecystokinin A receptor	0.017
Slc22a7	solute carrier family 22 (organic anion transporter), member 7	0.017
Ctrc	chymotrypsin C (caldecrin)	0.017
Aard	alanine and arginine rich domain containing protein	0.017
Chrna6	cholinergic receptor, nicotinic, alpha 6	0.017
Drd5	dopamine receptor D5	0.017
Pax6	paired box 6	0.017
Akap4	A kinase (PRKA) anchor protein 4	0.017
Reg3a	regenerating islet-derived 3 alpha	0.017
Agtr1b	angiotensin II receptor, type 1b	0.017
Atp7b	ATPase, Cu++ transporting, beta polypeptide	0.017
Sytl4	synaptotagmin-like 4	0.017
Drd2	dopamine receptor D2	0.017
Si	sucrase-isomaltase (alpha-glucosidase)	0.017
Adora3	adenosine A3 receptor	0.017
Crx	cone-rod homeobox	0.017
Pitx3	paired-like homeodomain 3	0.017
Entpd3	ectonucleoside triphosphate diphosphohydrolase 3	0.017
Gfap	glial fibrillary acidic protein	0.017
Olr1523	olfactory receptor 1523	0.017
Casp12	caspase 12	0.016
Trh	thyrotropin releasing hormone	0.016
Pth	parathyroid hormone	0.016
Pzp	pregnancy-zone protein	0.016
Wisp1	WNT1 inducible signaling pathway protein 1	0.016
Fga	fibrinogen alpha chain	0.016
Trpc4	transient receptor potential cation channel, subfamily C, member 4	0.016
Hr	hairless	0.016
Edn3	endothelin 3	0.016	Rat
Fosl2	fos-like antigen 2	0.016
Sult1c3	sulfotransferase family, cytosolic, 1C, member 3	0.016
Baat	bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase)	0.016
Cpxm2	carboxypeptidase X (M14 family), member 2	0.016
Prss1	protease, serine, 1 (trypsin 1)	0.016
Isl2	ISL LIM homeobox 2	0.015
Adam2	ADAM metallopeptidase domain 2	0.015
Stxbp2	syntaxin binding protein 2	0.015
Htr2b	5-hydroxytryptamine (serotonin) receptor 2B	0.015	Rat
Cacng1	calcium channel, voltage-dependent, gamma subunit 1	0.015
Ttr	transthyretin	0.015
F2	coagulation factor II (thrombin)	0.015
Plcb2	phospholipase C, beta 2	0.015
Rims1	regulating synaptic membrane exocytosis 1	0.015
A2m	alpha-2-macroglobulin	0.015
RGD1308165	similar to hypothetical protein MGC17337	0.015
Pga5	pepsinogen 5, group I	0.015
Gfi1	growth factor independent 1 transcription repressor	0.015
Gnat3	guanine nucleotide binding protein, alpha transducing 3	0.015
Slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.015
Slc1a2	solute carrier family 1 (glial high affinity glutamate transporter), member 2	0.015
Otc	ornithine carbamoyltransferase	0.015
Pbsn	probasin	0.015
Acsm2	acyl-CoA synthetase medium-chain family member 2	0.015
Cpb2	carboxypeptidase B2 (plasma)	0.015
Itgam	integrin, alpha M	0.015
Ugt2b5	UDP glucuronosyltransferase 2 family, polypeptide B5	0.015
Asgr1	asialoglycoprotein receptor 1	0.015
Pitx1	paired-like homeodomain 1	0.015
Sert1	Sertoli cell protein 1	0.015
Igfbp1	insulin-like growth factor binding protein 1	0.015
Abcc8	ATP-binding cassette, subfamily C (CFTR/MRP), member 8	0.014
Apba1	amyloid beta (A4) precursor protein-binding, family A, member 1	0.014
Acaa1b	acetyl-Coenzyme A acyltransferase 1B	0.014
Gna15	guanine nucleotide binding protein, alpha 15	0.014
Klrb1b	killer cell lectin-like receptor subfamily B member 1B	0.014
Sstr5	somatostatin receptor 5	0.014
Lrg1	leucine-rich alpha-2-glycoprotein 1	0.014
A1bg	alpha-1-B glycoprotein	0.014
Tacr1	tachykinin receptor 1	0.014
Cps1	carbamoyl-phosphate synthetase 1	0.014
Gucy1b2	guanylate cyclase 1, soluble, beta 2	0.014
Sh2d4a	SH2 domain containing 4A	0.014
Fgf7	fibroblast growth factor 7	0.014
LOC60591	calcium-activated potassium channel beta subunit	0.014
Spam1	sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)	0.014
Olfml2b	olfactomedin-like 2B	0.014
Ambp	alpha-1-microglobulin/bikunin precursor	0.014
Adm	adrenomedullin	0.014
Fgb	fibrinogen beta chain	0.014
Neurod2	neurogenic differentiation 2	0.014
P2rx1	purinergic receptor P2X, ligand-gated ion channel, 1	0.014
Adrb2	adrenergic, beta-2-, receptor, surface	0.014	Rat
Vom2r27	vomeronasal 2 receptor, 27	0.014
LOC100361261	rCG23560-like	0.013
Pnma1	paraneoplastic antigen MA1	0.013
Cnih2	cornichon homolog 2 (Drosophila)	0.013
Olr1278	olfactory receptor 1278	0.013
Orm1	orosomucoid 1	0.013
Ccl22	chemokine (C-C motif) ligand 22	0.013
Rshl1	radial spokehead-like 1	0.013
Cyp2c22	cytochrome P450, family 2, subfamily c, polypeptide 22	0.013
Calcb	calcitonin-related polypeptide, beta	0.013
Clec4f	C-type lectin domain family 4, member f	0.013
Cryba1	crystallin, beta A1	0.013
Ptger1	prostaglandin E receptor 1 (subtype EP1)	0.013
Pdc	phosducin	0.013
Cyp2c23	cytochrome P450, family 2, subfamily c, polypeptide 23	0.013
Mmp2	matrix metallopeptidase 2	0.013
Serpina6	serine (or cysteine) peptidase inhibitor, clade A, member 6	0.013	Rat
Il8rb	interleukin 8 receptor, beta	0.013
Rgs8	regulator of G-protein signaling 8	0.013
Fgf2	fibroblast growth factor 2	0.013
Tff1	trefoil factor 1	0.013
Prl8a4	prolactin family 8, subfamily a, member 4	0.013
Olr1641	olfactory receptor 1641	0.013
Ccdc49	coiled-coil domain containing 49	0.013
Itgad	integrin, alpha D	0.013
Mug1	murinoglobulin 1	0.012
Pmfbp1	polyamine modulated factor 1 binding protein 1	0.012
Grik3	glutamate receptor, ionotropic, kainate 3	0.012
Trhr	thyrotropin releasing hormone receptor	0.012
Tpbpa	trophoblast specific protein alpha	0.012
Kcnq2	potassium voltage-gated channel, KQT-like subfamily, member 2	0.012
Fgf17	fibroblast growth factor 17	0.012
Ugt2b	UDP glycosyltransferase 2 family, polypeptide B	0.012
Inhbe	inhibin beta E	0.012
Prss3	protease, serine, 3	0.012
Gpx6	glutathione peroxidase 6	0.012
Pnliprp1	pancreatic lipase-related protein 1	0.012
Ltbp3	latent transforming growth factor beta binding protein 3	0.012
Nkx2-1	NK2 homeobox 1	0.012
Apoc3	apolipoprotein C-III	0.012
Prl3d1	Prolactin family 3, subfamily d, member 1	0.012
Mr1	major histocompatibility complex, class I-related	0.012
Foxg1	forkhead box G1	0.012
Hsd17b6	hydroxysteroid (17-beta) dehydrogenase 6	0.012
Srd5a2	steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)	0.012
Cyp4a10	cytochrome P450, family 4, subfamily a, polypeptide 10	0.012
Col8a1	collagen, type VIII, alpha 1	0.012
Kif12	kinesin family member 12	0.012
Crhbp	corticotropin releasing hormone binding protein	0.012
Gja3	gap junction protein, alpha 3	0.012
Mas1	MAS1 oncogene	0.012
A1i3	alpha-1-inhibitor III	0.012
Cdh17	cadherin 17	0.012
Ehf	ets homologous factor	0.012
Scn10a	sodium channel, voltage-gated, type X, alpha subunit	0.012
Clstn3	calsyntenin 3	0.012
Mbl2	mannose-binding lectin (protein C) 2	0.012
Pcdh21	protocadherin 21	0.012
Thrsp	thyroid hormone responsive	0.011
Lin7b	lin-7 homolog b (C. elegans)	0.011
Klk1c10l2	kallikrein 1-related peptidase c10-like 2	0.011
Hrh2	histamine receptor H 2	0.011	Rat
Apoa4	apolipoprotein A-IV	0.011
Slc1a3	solute carrier family 1 (glial high affinity glutamate transporter), member 3	0.011
Btc	betacellulin	0.011
Cyp8b1	cytochrome P450, family 8, subfamily b, polypeptide 1	0.011
LOC100365112	carboxylesterase-like	0.011
Gcnt3	glucosaminyl (N-acetyl) transferase 3, mucin type	0.011
Slc25a26	solute carrier family 25, member 26	0.011
Cartpt	CART prepropeptide	0.011
Ucn	urocortin	0.011
Muc5ac	mucin 5AC, oligomeric mucus/gel-forming	0.011
Adh1	alcohol dehydrogenase 1 (class I)	0.011
Slc7a2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	0.011
Kcnj10	potassium inwardly-rectifying channel, subfamily J, member 10	0.011
Slc5a5	solute carrier family 5 (sodium iodide symporter), member 5	0.011
G6pc	glucose-6-phosphatase, catalytic subunit	0.011
C4b	complement component 4B (Chido blood group)	0.011
Hmgcs2	3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial)	0.011
Smgb	neonatal submandibular gland protein B	0.011
Tbx5	T-box 5	0.011
Tpo	thyroid peroxidase	0.011
Cdkn2b	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)	0.011
Rab15	RAB15, member RAS oncogene family	0.011
LOC100359800	rCG64478-like	0.011
Slco2a1	solute carrier organic anion transporter family, member 2a1	0.011
RGD1309501	hypothetical LOC305552	0.011
Tac2	tachykinin 2	0.011
Plg	plasminogen	0.011
Akr1c18	aldo-keto reductase family 1, member C18	0.011
Tmem158	transmembrane protein 158	0.011
Grm2	glutamate receptor, metabotropic 2	0.010
Angpt2	angiopoietin 2	0.010
Pnck	pregnancy upregulated non-ubiquitously expressed CaM kinase	0.010
Prdm2	PR domain containing 2, with ZNF domain	0.010
Mcpt1	mast cell protease 1	0.010
Anubl1	AN1, ubiquitin-like, homolog (Xenopus laevis)	0.010
Cxcl6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.010
Pde4c	phosphodiesterase 4C, cAMP-specific (phosphodiesterase E1 dunce homolog, Drosophila)	0.010
Olr1470	olfactory receptor 1470	0.010
Esr2	estrogen receptor 2 (ER beta)	0.010
Wisp2	WNT1 inducible signaling pathway protein 2	0.010
Slco2b1	solute carrier organic anion transporter family, member 2b1	0.010
Rgs9	regulator of G-protein signaling 9	0.010
Cyp2f4	cytochrome P450, family 2, subfamily f, polypeptide 4	0.010
Gsg1l	GSG1-like	0.010
RGD1564327	similar to integrin alpha 8	0.010
Ang1	angiogenin, ribonuclease A family, member 1	0.010
Slc30a2	solute carrier family 30 (zinc transporter), member 2	0.010
Il6	interleukin 6	0.010
Nog	noggin	0.010
Klrb1c	killer cell lectin-like receptor subfamily B member 1C	0.010
Rnase1	ribonuclease, RNase A family, 1 (pancreatic)	0.010
Dnah2	dynein, axonemal, heavy chain 2	0.010
Havcr1	hepatitis A virus cellular receptor 1	0.010
Slit3	slit homolog 3 (Drosophila)	0.010