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Danio rerio

5 genes annotated in zebrafish

regulation of synapse structure and activity

Any process that modulates the physical form or the activity of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of synapse structure and activity"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of synapse structure and activity" (in gray)

Name	Description	Probability	Func Analog Organism
boc	brother of CDO	0.715
robo2	roundabout homolog 2	0.375
slc17a6b	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6b	0.343	Zebrafish
nf1a	neurofibromin 1a	0.219	Fly
nlgn4b	neuroligin 4b	0.169
nlgn2b	neuroligin 2b	0.118
smo	smoothened homolog (Drosophila)	0.104
thsd7a	thrombospondin, type I, domain containing 7A	0.094
spsb4a	splA/ryanodine receptor domain and SOCS box containing 4a	0.090
scn8aa	sodium channel, voltage-gated, type VIII, alpha a	0.081
flot1	flotillin 1	0.079
nxph1	neurexophilin 1	0.078
fbn2b	fibrillin 2b	0.076
cacna1da	calcium channel, voltage-dependent, L type, alpha 1D subunit, a	0.069
drd2b	dopamine receptor D2b	0.067	Rat
ephb4b	eph receptor B4b	0.065
gro2	groucho 2	0.065	Worm
roraa	RAR-related orphan receptor A, paralog a	0.061
olfm2	olfactomedin 2	0.057
atp1b2a	ATPase, Na+/K+ transporting, beta 2a polypeptide	0.056
rnd3a	Rho family GTPase 3a	0.055
lhx2b	LIM homeobox 2b	0.052
sema3aa	semaphorin 3aa	0.050
kal1a	Kallmann syndrome 1a sequence	0.049
lef1	lymphocyte enhancer binding factor 1	0.046
sh3gl1b	SH3-domain GRB2-like 1b	0.046	Fly
dlg2	discs, large (Drosophila) homolog 2	0.043
arnt2	aryl hydrocarbon receptor nuclear translocator 2	0.043
ikzf5	IKAROS family zinc finger 5	0.043
unc45b	unc-45 homolog B (C. elegans)	0.041
cacnb1	calcium channel, voltage-dependent, beta 1 subunit	0.040
bambia	BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a	0.040
hmcn2	hemicentin 2	0.040
s1pr2	sphingosine-1-phosphate receptor 2	0.040
bmpr2b	bone morphogenetic protein receptor, type II b (serine/threonine kinase)	0.039	Fly
frem3	Fras1 related extracellular matrix 3	0.037
ptpra	protein tyrosine phosphatase, receptor type, A	0.037
pax8	paired box gene 8	0.036
cntn1a	contactin 1a	0.035
nkd1	naked cuticle homolog 1 (Drosophila)	0.035
nog2	noggin 2	0.034
unc5b	unc-5 homolog B (C. elegans)	0.033
aurka	aurora kinase A	0.033
si:dkeyp-104h9.6	si:dkeyp-104h9.6	0.033
dlg1	discs, large (Drosophila) homolog 1	0.033	Fly
lims1	LIM and senescent cell antigen-like domains 1	0.032
fstl1b	follistatin-like 1b	0.031
nlgn2a	neuroligin 2a	0.031
ptk2.1	protein tyrosine kinase 2a	0.031	Mouse Fly
lama2	laminin, alpha 2	0.030
gli2a	GLI-Kruppel family member GLI2a	0.029
ptprk	protein tyrosine phosphatase, receptor type, K	0.029
gli1	GLI-Kruppel family member 1	0.029
nrg2a	neuregulin 2a	0.029
nrp2b	neuropilin 2b	0.028
efnb2a	ephrin B2a	0.026
six3b	sine oculis homeobox homolog 3b	0.026
pacsin3	protein kinase C and casein kinase substrate in neurons 3	0.025
gad2	glutamate decarboxylase 2	0.025
dmd	dystrophin	0.024
barhl1.2	BarH-like 1.2	0.024
trim33	tripartite motif-containing 33	0.024
tjp2a	tight junction protein 2a (zona occludens 2)	0.022
cdh23	cadherin-like 23	0.022
wnt10a	wingless-type MMTV integration site family, member 10a	0.022
rargb	retinoic acid receptor, gamma b	0.021
im:7137555	im:7137555	0.021
szl	sizzled	0.021
sncb	synuclein, beta	0.020
snap25a	synaptosome-associated protein 25a	0.020
nlgn3a	neuroligin 3a	0.019	Mouse Fly
zgc:86759	zgc:86759	0.019
robo1	roundabout homolog 1	0.019	Zebrafish
wnt5a	wingless-type MMTV integration site family, member 5a	0.019
ldb2a	LIM-domain binding factor 2a	0.019
cntn2	contactin 2	0.019
phox2a	paired-like homeobox 2a	0.018
ttna	titin a	0.018
lama4	laminin, alpha 4	0.018	Fly
six1a	sine oculis homeobox homolog 1a	0.018	Mouse
zgc:85975	zgc:85975	0.017
chrnd	cholinergic receptor, nicotinic, delta polypeptide	0.017
akt2	v-akt murine thymoma viral oncogene homolog 2	0.017	Fly
foxp2	forkhead box P2	0.017
pcdh15a	protocadherin 15a	0.016
stac3	SH3 and cysteine rich domain 3	0.016
mmp9	matrix metalloproteinase 9	0.016
igfbp3	insulin-like growth factor binding protein 3	0.015
psen1	presenilin 1	0.015
pbx4	pre-B-cell leukemia transcription factor 4	0.015
zgc:112072	zgc:112072	0.015
myo6b	myosin VIb	0.014
bmpr2a	bone morphogenetic protein receptor, type II a (serine/threonine kinase)	0.014	Fly
hspg2	heparan sulfate proteoglycan 2	0.014
atp6v0cb	ATPase, H+ transporting, lysosomal, V0 subunit c, b	0.014
kif5aa	kinesin family member 5A, a	0.014
coro1a	coronin, actin binding protein, 1A	0.014
disc1	disrupted in schizophrenia 1	0.014	Mouse
dpysl4	dihydropyrimidinase-like 4	0.014
ndrg4	N-myc downstream regulated gene 4	0.013
alcamb	activated leukocyte cell adhesion molecule b	0.013
pfn2	profilin 2	0.013
camk2g1	calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 1	0.013	Fly
zgc:162964	zgc:162964	0.013
ncam2	neural cell adhesion molecule 2	0.013
smyd1b	SET and MYND domain containing 1b	0.013
nhsl1a	NHS-like 1a	0.013
pcdh8	protocadherin 8	0.012
vasp	vasodilator-stimulated phosphoprotein	0.012	Fly
arhgef7b	Rho guanine nucleotide exchange factor (GEF) 7b	0.012
capn9	calpain 9	0.012
dlat	dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)	0.012
gad1b	glutamate decarboxylase 1b	0.012
pknox1.2	pbx/knotted 1 homeobox 1.2	0.012
ndr2	nodal-related 2	0.012
grhl2b	grainyhead-like 2b (Drosophila)	0.011
ebf3	early B-cell factor 3	0.011
fcer1gl	Fc receptor, IgE, high affinity I, gamma polypeptide like	0.011
aldocb	aldolase C, fructose-bisphosphate, b	0.011
rbfox2	RNA binding protein, fox-1 homolog (C. elegans) 2	0.011
egfl6	EGF-like-domain, multiple 6	0.011
ctbp2	C-terminal binding protein 2	0.011
zgc:110788	zgc:110788	0.011
frem1a	Fras1 related extracellular matrix 1a	0.011
foxe1	forkhead box E1 (thyroid transcription factor 2)	0.011
nlgn1	neuroligin 1	0.011
sept6	septin 6	0.011
hapln3	hyaluronan and proteoglycan link protein 3	0.011
myd88	myeloid differentiation primary response gene (88)	0.011
rc3	rabconnectin 3	0.011
efna1b	ephrin A1b	0.011
extl3	exostoses (multiple)-like 3	0.010
slit3	slit (Drosophila) homolog 3	0.010	Zebrafish
mxi1	max interacting protein	0.010
skia	nuclear oncoprotein skia	0.010