IMP

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Danio rerio

10 genes annotated in zebrafish

Multi-species View

negative regulation of peptidase activity

GO:0010466

Any process that stops or reduces the rate of peptidase activity, the hydrolysis of peptide bonds within proteins.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of peptidase activity"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of peptidase activity" (in gray)

Name	Description	Probability	Func Analog Organism
wu:fj39b01	wu:fj39b01	0.189
adipor2	adiponectin receptor 2	0.168
ptf1a	pancreas specific transcription factor, 1a	0.156
hhip	hedgehog interacting protein	0.155
ass1	argininosuccinate synthetase 1	0.141
furina	furin (paired basic amino acid cleaving enzyme) a	0.128	Human
igf1ra	insulin-like growth factor 1a receptor	0.091
mdm2	transformed 3T3 cell double minute 2 homolog (mouse)	0.080
stc1l	stanniocalcin 1, like	0.076
pcsk5b	proprotein convertase subtilisin/kexin type 5b	0.066
bbc3	BCL2 binding component 3	0.061
hbbe1.1	hemoglobin beta embryonic-1.1	0.055
map2k4a	mitogen-activated protein kinase kinase 4a	0.054
cdh4	cadherin 4, retinal	0.052
adipoql	adiponectin, C1Q and collagen domain containing, like	0.052	Zebrafish
bcl2l1	bcl2-like 1	0.050
shmt2	serine hydroxymethyltransferase 2 (mitochondrial)	0.049
ppp1r12a	protein phosphatase 1, regulatory (inhibitor) subunit 12A	0.048
calcr	calcitonin receptor	0.047
adipoql2	adiponectin, C1Q and collagen domain containing, like 2	0.047	Zebrafish
bhmt	betaine-homocysteine methyltransferase	0.046
furinb	furin (paired basic amino acid cleaving enzyme) b	0.044	Human
zgc:56304	zgc:56304	0.044
nf1a	neurofibromin 1a	0.041
rhag	Rhesus blood group-associated glycoprotein	0.040
vwf	von Willebrand factor	0.040
pcsk5a	proprotein convertase subtilisin/kexin type 5a	0.039
pcsk9	proprotein convertase subtilisin/kexin type 9	0.038
itih2	inter-alpha (globulin) inhibitor H2	0.036
s1pr3	sphingosine-1-phosphate receptor 3	0.033
ldb1a	LIM-domain binding factor 1a	0.033
pcsk1	proprotein convertase subtilisin/kexin type 1	0.033
sepp1b	selenoprotein P, plasma, 1b	0.032
nrg1	neuregulin 1	0.029
dip2c	DIP2 disco-interacting protein 2 homolog C (Drosophila)	0.029
ctsba	cathepsin B, a	0.029
pcsk7	proprotein convertase subtilisin/kexin type 7	0.029
pcsk2	proprotein convertase subtilisin/kexin type 2	0.029
serpinf2	serine (or cysteine) peptidase inhibitor, clade F, member 2	0.028
ripk2	receptor-interacting serine-threonine kinase 2	0.026
mcl1b	myeloid cell leukemia sequence 1b	0.025
hsd17b1	hydroxysteroid (17-beta) dehydrogenase 1	0.025
nrg2a	neuregulin 2a	0.024
tp53bp2	tumor protein p53 binding protein, 2	0.022
zbtb4	zinc finger and BTB domain containing 4	0.022
mbtps1	membrane-bound transcription factor protease, site 1	0.022
wu:fv91b12	wu:fv91b12	0.022
insrb	insulin receptor b	0.022	Zebrafish
zgc:161979	zgc:161979	0.022
baxa	bcl2-associated X protein, a	0.021	Zebrafish
mst1	macrophage stimulating 1 (hepatocyte growth factor-like)	0.021
angptl2	angiopoietin-like 2	0.021
bida	BH3 interacting domain death agonist	0.020
pmaip1	phorbol-12-myristate-13-acetate-induced protein 1	0.020
per2	period homolog 2 (Drosophila)	0.019
LOC566708	FL cytokine receptor-like	0.019
wnt9b	wingless-type MMTV integration site family, member 9B	0.019
zgc:56116	zgc:56116	0.018
ywhai	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, iota polypeptide	0.018
slc1a2b	solute carrier family 1 (glial high affinity glutamate transporter), member 2b	0.018
nfkbiab	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b	0.018
oc90	otoconin 90	0.018
hgfb	hepatocyte growth factor b	0.018
LOC567131	calcitonin gene-related peptide type 1 receptor-like	0.018
sfrp1b	secreted frizzled-related protein 1b	0.017
fos	v-fos FBJ murine osteosarcoma viral oncogene homolog	0.017
notum3	notum 3	0.017
lcp1	lymphocyte cytosolic plastin 1	0.017
trim13	tripartite motif-containing 13	0.017
rspo1	R-spondin homolog (Xenopus laevis)	0.016
slc4a2a	solute carrier family 4, anion exchanger, member 2a	0.016
trpv6	transient receptor potential cation channel, subfamily V, member 6	0.016
snap25a	synaptosome-associated protein 25a	0.016
hoxc13b	homeo box C13b	0.016
pklr	pyruvate kinase, liver and RBC	0.015
zgc:85866	zgc:85866	0.015
mipa	major intrinsic protein of lens fiber a	0.015
adipor1b	adiponectin receptor 1b	0.014
plg	plasminogen	0.014
nr5a1b	nuclear receptor subfamily 5, group A, member 1b	0.014
lhb	luteinizing hormone, beta polypeptide	0.014
cyp19a1a	cytochrome P450, family 19, subfamily A, polypeptide 1a	0.014
si:dkey-222f8.3	si:dkey-222f8.3	0.014
igfbp1b	insulin-like growth factor binding protein 1b	0.014
atic	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase	0.014
cyp17a1	cytochrome P450, family 17, subfamily A, polypeptide 1	0.014
atp6v1a	ATPase, H+ transporting, lysosomal V1 subunit A	0.014
inhbaa	inhibin, beta Aa	0.014
usp5	ubiquitin specific protease 5	0.014
rnasel1	ribonuclease like 1	0.013
ptger4b	prostaglandin E receptor 4 (subtype EP4) b	0.013
chmp5	chromatin modifying protein 5	0.013
mcl1a	myeloid cell leukemia sequence 1a	0.013
cp	ceruloplasmin	0.013
ncoa2	nuclear receptor coactivator 2	0.013
aqp12	aquaporin 12	0.013
ghra	growth hormone receptor a	0.013
ptgs1	prostaglandin-endoperoxide synthase 1	0.013
numbl	numb homolog (Drosophila)-like	0.013
zgc:92502	zgc:92502	0.012
nr4a3	nuclear receptor subfamily 4, group A, member 3	0.012
ada	adenosine deaminase	0.012
cps1	carbamoyl-phosphate synthase 1, mitochondrial	0.012
ppp2r1a	protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform	0.012
mst1rb	macrophage stimulating 1 receptor (c-met-related tyrosine kinase), b	0.012
neu4	sialidase 4	0.012
cldni	claudin i	0.011
uox	urate oxidase	0.011
foxi3b	forkhead box I3b	0.011
foxe3	forkhead box E3	0.011
mta2	metastasis associated 1 family, member 2	0.011
gpx4a	glutathione peroxidase 4a	0.011
sardh	sarcosine dehydrogenase	0.011
nfia	nuclear factor I/A	0.011
adora2b	adenosine A2b receptor	0.011
tgfbi	transforming growth factor, beta-induced	0.011
slc7a6	solute carrier family 7 (cationic amino acid transporter, y+ system), member 6	0.011
lmx1b.1	LIM homeobox transcription factor 1, beta 1	0.011
henmt1	HEN1 methyltransferase homolog 1 (Arabidopsis)	0.011
bad	BCL2-antagonist of cell death	0.011
apom	apolipoprotein M	0.011
zgc:85727	zgc:85727	0.011
zgc:56530	zgc:56530	0.010	Human
arntl1b	aryl hydrocarbon receptor nuclear translocator-like 1b	0.010
bmp15	bone morphogenetic protein 15	0.010
calcrla	calcitonin receptor-like a	0.010
spi1l	spleen focus forming virus (SFFV) proviral integration oncogene spi1 like	0.010
ces2	carboxylesterase 2 (intestine, liver)	0.010
vegfab	vascular endothelial growth factor Ab	0.010	Human
igf1rb	insulin-like growth factor 1b receptor	0.010
f5	coagulation factor V	0.010
LOC562316	klotho-like	0.010