IMP
Process View
The network for 'negative regulation of growth of symbiont in host' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
negative regulation of growth of symbiont in host
Any process in which the symbiont stops, prevents or reduces its increase in size or mass within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| TLR4 | toll-like receptor 4 | 0.958 | |
| TIRAP | toll-interleukin 1 receptor (TIR) domain containing adaptor protein | 0.738 | |
| PDCD6IP | programmed cell death 6 interacting protein | 0.609 | |
| DHCR7 | 7-dehydrocholesterol reductase | 0.297 | |
| SC4MOL | sterol-C4-methyl oxidase-like | 0.157 | |
| IRAK4 | interleukin-1 receptor-associated kinase 4 | 0.108 | |
| LRSAM1 | leucine rich repeat and sterile alpha motif containing 1 | 0.107 | |
| INSIG1 | insulin induced gene 1 | 0.103 | |
| DMBT1 | deleted in malignant brain tumors 1 | 0.090 | |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.086 | |
| SH3GL2 | SH3-domain GRB2-like 2 | 0.081 | |
| SAMHD1 | SAM domain and HD domain 1 | 0.074 | |
| MYD88 | myeloid differentiation primary response gene (88) | 0.074 | |
| SQLE | squalene epoxidase | 0.071 | |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.066 | |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.064 | |
| RAB5A | RAB5A, member RAS oncogene family | 0.063 | |
| DHCR24 | 24-dehydrocholesterol reductase | 0.058 | |
| IRAK1 | interleukin-1 receptor-associated kinase 1 | 0.058 | |
| PDCD6 | programmed cell death 6 | 0.053 | |
| FADS1 | fatty acid desaturase 1 | 0.044 | |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | 0.043 | |
| SFTPD | surfactant protein D | 0.038 | |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.034 | |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 | 0.031 | |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.031 | |
| EIF1B | eukaryotic translation initiation factor 1B | 0.031 | |
| C4BPA | complement component 4 binding protein, alpha | 0.031 | |
| JAK1 | Janus kinase 1 | 0.030 | |
| FADS2 | fatty acid desaturase 2 | 0.029 | |
| RNF41 | ring finger protein 41 | 0.024 | |
| LRP1 | low density lipoprotein receptor-related protein 1 | 0.023 | |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.022 | |
| ELANE | elastase, neutrophil expressed | 0.021 | |
| CTSG | cathepsin G | 0.020 | |
| ARAF | v-raf murine sarcoma 3611 viral oncogene homolog | 0.019 | |
| MASP1 | mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) | 0.019 | |
| PTPN23 | protein tyrosine phosphatase, non-receptor type 23 | 0.018 | |
| CHMP4B | chromatin modifying protein 4B | 0.018 | |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) | 0.018 | |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) | 0.017 | |
| SPOP | speckle-type POZ protein | 0.017 | |
| MPO | myeloperoxidase | 0.017 | |
| CFD | complement factor D (adipsin) | 0.017 | |
| FDPS | farnesyl diphosphate synthase | 0.016 | |
| ACACA | acetyl-CoA carboxylase alpha | 0.016 | |
| STAP2 | signal transducing adaptor family member 2 | 0.016 | |
| CD2AP | CD2-associated protein | 0.015 | |
| TLR2 | toll-like receptor 2 | 0.014 | |
| ARL8B | ADP-ribosylation factor-like 8B | 0.014 | |
| PLIN1 | perilipin 1 | 0.014 | |
| SREBF1 | sterol regulatory element binding transcription factor 1 | 0.014 | |
| VPS37C | vacuolar protein sorting 37 homolog C (S. cerevisiae) | 0.014 | |
| LTF | lactotransferrin | 0.014 | |
| PRTN3 | proteinase 3 | 0.014 | |
| AZU1 | azurocidin 1 | 0.012 | |
| RPS6KA6 | ribosomal protein S6 kinase, 90kDa, polypeptide 6 | 0.012 | |
| HP | haptoglobin | 0.011 | |
| SHOC2 | soc-2 suppressor of clear homolog (C. elegans) | 0.011 | |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.011 | |
| CMA1 | chymase 1, mast cell | 0.011 | |
| TLR7 | toll-like receptor 7 | 0.011 | |
| TRIP4 | thyroid hormone receptor interactor 4 | 0.011 | |
| FXYD1 | FXYD domain containing ion transport regulator 1 | 0.010 | |
| LTC4S | leukotriene C4 synthase | 0.010 | |
| SFTPB | surfactant protein B | 0.010 | |
| ALDOC | aldolase C, fructose-bisphosphate | 0.010 | |
| BST1 | bone marrow stromal cell antigen 1 | 0.010 |
Loading network...
Drosophila melanogaster
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Pi3K92E | CG4141 gene product from transcript CG4141-RB | 0.013 |
Loading network...
Mus musculus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Tnf | tumor necrosis factor | 0.999 | |
| Il10 | interleukin 10 | 0.984 | |
| Ifng | interferon gamma | 0.961 | |
| Lta | lymphotoxin A | 0.924 | |
| Apoe | apolipoprotein E | 0.855 | |
| Nfkb2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 | 0.763 | |
| Map3k14 | mitogen-activated protein kinase kinase kinase 14 | 0.721 | |
| Tnfrsf1a | tumor necrosis factor receptor superfamily, member 1a | 0.689 | |
| Pik3cd | phosphatidylinositol 3-kinase catalytic delta polypeptide | 0.591 | |
| Cd19 | CD19 antigen | 0.567 | |
| Casp4 | caspase 4, apoptosis-related cysteine peptidase | 0.504 | |
| Tnfrsf1b | tumor necrosis factor receptor superfamily, member 1b | 0.458 | |
| Cd40 | CD40 antigen | 0.411 | |
| Pdcd1 | programmed cell death 1 | 0.361 | |
| Elane | elastase, neutrophil expressed | 0.354 | |
| Ngp | neutrophilic granule protein | 0.352 | |
| Cxcl13 | chemokine (C-X-C motif) ligand 13 | 0.351 | |
| Cxcr5 | chemokine (C-X-C motif) receptor 5 | 0.312 | |
| Cma1 | chymase 1, mast cell | 0.308 | |
| Ctsg | cathepsin G | 0.302 | |
| Tnfsf14 | tumor necrosis factor (ligand) superfamily, member 14 | 0.288 | |
| Klrk1 | killer cell lectin-like receptor subfamily K, member 1 | 0.254 | |
| Irf1 | interferon regulatory factor 1 | 0.245 | |
| Pik3ap1 | phosphoinositide-3-kinase adaptor protein 1 | 0.195 | |
| Cd44 | CD44 antigen | 0.193 | |
| Gzmb | granzyme B | 0.192 | |
| Ltb | lymphotoxin B | 0.176 | |
| Ccl4 | chemokine (C-C motif) ligand 4 | 0.170 | |
| Tnfsf11 | tumor necrosis factor (ligand) superfamily, member 11 | 0.168 | |
| Fasl | Fas ligand (TNF superfamily, member 6) | 0.159 | |
| Unc93b1 | unc-93 homolog B1 (C. elegans) | 0.159 | |
| Camp | cathelicidin antimicrobial peptide | 0.158 | |
| Ltf | lactotransferrin | 0.153 | |
| Mmp9 | matrix metallopeptidase 9 | 0.139 | |
| Ticam1 | toll-like receptor adaptor molecule 1 | 0.124 | |
| Pou2af1 | POU domain, class 2, associating factor 1 | 0.118 | |
| Btk | Bruton agammaglobulinemia tyrosine kinase | 0.108 | |
| Nfkb1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 | 0.106 | |
| Mpo | myeloperoxidase | 0.102 | |
| Cpa3 | carboxypeptidase A3, mast cell | 0.092 | |
| Igh | immunoglobulin heavy chain complex | 0.091 | |
| Il2rb | interleukin 2 receptor, beta chain | 0.086 | |
| Il7 | interleukin 7 | 0.079 | |
| Gbp1 | guanylate binding protein 1 | 0.079 | |
| Batf | basic leucine zipper transcription factor, ATF-like | 0.078 | |
| Irf4 | interferon regulatory factor 4 | 0.077 | |
| Stat1 | signal transducer and activator of transcription 1 | 0.073 | |
| Thra | thyroid hormone receptor alpha | 0.072 | |
| Vdr | vitamin D receptor | 0.067 | |
| Ooep | oocyte expressed protein homolog (dog) | 0.064 | |
| Jak3 | Janus kinase 3 | 0.063 | |
| Lyz2 | lysozyme 2 | 0.062 | |
| Mmp8 | matrix metallopeptidase 8 | 0.061 | |
| Prf1 | perforin 1 (pore forming protein) | 0.060 | |
| Stat2 | signal transducer and activator of transcription 2 | 0.059 | |
| Gzmk | granzyme K | 0.059 | |
| Icos | inducible T-cell co-stimulator | 0.058 | |
| Pparg | peroxisome proliferator activated receptor gamma | 0.057 | |
| Klrg1 | killer cell lectin-like receptor subfamily G, member 1 | 0.057 | |
| Cd96 | CD96 antigen | 0.054 | |
| Ccl2 | chemokine (C-C motif) ligand 2 | 0.054 | |
| Il4 | interleukin 4 | 0.054 | |
| Igtp | interferon gamma induced GTPase | 0.053 | |
| Pla2g2a | phospholipase A2, group IIA (platelets, synovial fluid) | 0.053 | |
| Ccr2 | chemokine (C-C motif) receptor 2 | 0.052 | |
| Ifnar2 | interferon (alpha and beta) receptor 2 | 0.052 | |
| H2-M9 | histocompatibility 2, M region locus 9 | 0.051 | |
| Il1r1 | interleukin 1 receptor, type I | 0.050 | |
| Duox2 | dual oxidase 2 | 0.049 | |
| Ms4a3 | membrane-spanning 4-domains, subfamily A, member 3 | 0.049 | |
| Nkg7 | natural killer cell group 7 sequence | 0.048 | |
| Ncr1 | natural cytotoxicity triggering receptor 1 | 0.047 | |
| Il1b | interleukin 1 beta | 0.046 | |
| Siglec1 | sialic acid binding Ig-like lectin 1, sialoadhesin | 0.046 | |
| Cav1 | caveolin 1, caveolae protein | 0.045 | |
| Relb | avian reticuloendotheliosis viral (v-rel) oncogene related B | 0.045 | |
| Ldlr | low density lipoprotein receptor | 0.045 | |
| Tlr2 | toll-like receptor 2 | 0.045 | |
| Fgr | Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog | 0.041 | |
| Xcl1 | chemokine (C motif) ligand 1 | 0.041 | |
| Prg2 | proteoglycan 2, bone marrow | 0.039 | |
| Uba7 | ubiquitin-like modifier activating enzyme 7 | 0.039 | |
| Slfn1 | schlafen 1 | 0.036 | |
| Ubd | ubiquitin D | 0.035 | |
| Nos2 | nitric oxide synthase 2, inducible | 0.034 | |
| Ifitm6 | interferon induced transmembrane protein 6 | 0.033 | |
| Cxcl10 | chemokine (C-X-C motif) ligand 10 | 0.032 | |
| Fcer1a | Fc receptor, IgE, high affinity I, alpha polypeptide | 0.031 | |
| Ccr7 | chemokine (C-C motif) receptor 7 | 0.031 | |
| Tlr4 | toll-like receptor 4 | 0.031 | |
| Lag3 | lymphocyte-activation gene 3 | 0.030 | |
| S100a9 | S100 calcium binding protein A9 (calgranulin B) | 0.030 | |
| Card11 | caspase recruitment domain family, member 11 | 0.029 | |
| Cd40lg | CD40 ligand | 0.029 | |
| Naip6 | NLR family, apoptosis inhibitory protein 6 | 0.029 | |
| Socs1 | suppressor of cytokine signaling 1 | 0.028 | |
| Mcpt8 | mast cell protease 8 | 0.028 | |
| Rsad2 | radical S-adenosyl methionine domain containing 2 | 0.028 | |
| Dsg4 | desmoglein 4 | 0.028 | |
| Cidec | cell death-inducing DFFA-like effector c | 0.028 |