The network for 'positive regulation of neutrophil chemotaxis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of neutrophil chemotaxis

Any process that increases the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.

Homo sapiens
Name Description Probability Func Analog Organism
CCR5 chemokine (C-C motif) receptor 5 1.000
CCL5 chemokine (C-C motif) ligand 5 0.998
CCL4 chemokine (C-C motif) ligand 4 0.949
IL1B interleukin 1, beta 0.918
CXCL9 chemokine (C-X-C motif) ligand 9 0.911
CCR7 chemokine (C-C motif) receptor 7 0.857
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.832
CXCR4 chemokine (C-X-C motif) receptor 4 0.783
CCL22 chemokine (C-C motif) ligand 22 0.758
IL8 interleukin 8 0.642
CCR4 chemokine (C-C motif) receptor 4 0.587
CCL8 chemokine (C-C motif) ligand 8 0.506
IL12B interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) 0.486
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 0.469
CCL2 chemokine (C-C motif) ligand 2 0.450
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.421
IFNG interferon, gamma 0.411
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 0.401
IL2RB interleukin 2 receptor, beta 0.400
CCL7 chemokine (C-C motif) ligand 7 0.378
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.337
CCL3 chemokine (C-C motif) ligand 3 0.310
CXCL2 chemokine (C-X-C motif) ligand 2 0.292
CCL19 chemokine (C-C motif) ligand 19 0.284
IL2RG interleukin 2 receptor, gamma 0.271
PLEK pleckstrin 0.247
CCL11 chemokine (C-C motif) ligand 11 0.231
CCR1 chemokine (C-C motif) receptor 1 0.200
IL6 interleukin 6 (interferon, beta 2) 0.186
MMP2 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) 0.179
CCL13 chemokine (C-C motif) ligand 13 0.174
CXCL13 chemokine (C-X-C motif) ligand 13 0.162
IL1RN interleukin 1 receptor antagonist 0.154
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.153
IL1R1 interleukin 1 receptor, type I 0.150
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 0.149
CXCL10 chemokine (C-X-C motif) ligand 10 0.147
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.126
CXCL3 chemokine (C-X-C motif) ligand 3 0.123
CCR2 chemokine (C-C motif) receptor 2 0.123
TNF tumor necrosis factor 0.113
IL10 interleukin 10 0.109
CCL20 chemokine (C-C motif) ligand 20 0.103
IL1R2 interleukin 1 receptor, type II 0.101
MMP9 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) 0.086
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 and major histocompatibility complex, class II, DR beta 1 0.086
DPP4 dipeptidyl-peptidase 4 0.079
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 0.072
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.072
CXCL11 chemokine (C-X-C motif) ligand 11 0.062
ICAM1 intercellular adhesion molecule 1 0.062
TGFB1 transforming growth factor, beta 1 0.058
LTA lymphotoxin alpha (TNF superfamily, member 1) 0.054
CD40LG CD40 ligand 0.052
VCAM1 vascular cell adhesion molecule 1 0.047
IL16 interleukin 16 (lymphocyte chemoattractant factor) 0.043
SELE selectin E 0.038
AQP9 aquaporin 9 0.036
IRF4 interferon regulatory factor 4 0.036
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 0.035
CXCL5 chemokine (C-X-C motif) ligand 5 0.033
CXCR3 chemokine (C-X-C motif) receptor 3 0.032
BCL2A1 BCL2-related protein A1 0.032
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 0.031
LAIR1 leukocyte-associated immunoglobulin-like receptor 1 0.030
TLR2 toll-like receptor 2 0.030
IDE insulin-degrading enzyme 0.029
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 0.029
MMP12 matrix metallopeptidase 12 (macrophage elastase) 0.029
IL7R interleukin 7 receptor 0.027
IL10RA interleukin 10 receptor, alpha 0.026
SLAMF7 SLAM family member 7 0.026
CCL21 chemokine (C-C motif) ligand 21 0.024
UBE2R2 ubiquitin-conjugating enzyme E2R 2 0.021
CD93 CD93 molecule 0.020
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 0.020
RGS1 regulator of G-protein signaling 1 0.019
UBD ubiquitin D 0.018
C3AR1 complement component 3a receptor 1 0.018
PLAUR plasminogen activator, urokinase receptor 0.018
CCR3 chemokine (C-C motif) receptor 3 0.018
TLR4 toll-like receptor 4 0.017
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A 0.017
RUNX3 runt-related transcription factor 3 0.017
CXCL6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) 0.017
IL18RAP interleukin 18 receptor accessory protein 0.017
HLA-DRA major histocompatibility complex, class II, DR alpha 0.015
IRAK2 interleukin-1 receptor-associated kinase 2 0.015
MYD88 myeloid differentiation primary response gene (88) 0.014
RHOC ras homolog gene family, member C 0.014
RHOA ras homolog gene family, member A 0.014
IL21R interleukin 21 receptor 0.013
CXCR2 chemokine (C-X-C motif) receptor 2 0.013
IL1A interleukin 1, alpha 0.013
FPR1 formyl peptide receptor 1 0.013
AKT2 v-akt murine thymoma viral oncogene homolog 2 0.013
DARC Duffy blood group, chemokine receptor 0.013
LTB lymphotoxin beta (TNF superfamily, member 3) 0.012
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 0.012
EBI3 Epstein-Barr virus induced 3 0.011
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
Ccl3 chemokine (C-C motif) ligand 3 0.988
Selp selectin, platelet 0.974
Ccl2 chemokine (C-C motif) ligand 2 0.969
Ccr2 chemokine (C-C motif) receptor 2 0.967
Ccr1 chemokine (C-C motif) receptor 1 0.959
Itgax integrin alpha X 0.906
Csf3r colony stimulating factor 3 receptor (granulocyte) 0.836
Ccl4 chemokine (C-C motif) ligand 4 0.745
C3ar1 complement component 3a receptor 1 0.732
Il1b interleukin 1 beta 0.732
Ccr5 chemokine (C-C motif) receptor 5 0.712
Ccl8 chemokine (C-C motif) ligand 8 0.703
Fcgr1 Fc receptor, IgG, high affinity I 0.552
Rac1 RAS-related C3 botulinum substrate 1 0.538
Fgr Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog 0.499
Batf basic leucine zipper transcription factor, ATF-like 0.492
C5ar1 complement component 5a receptor 1 0.475
Slfn1 schlafen 1 0.473
AF251705 cDNA sequence AF251705 0.473
Il1rn interleukin 1 receptor antagonist 0.437
H2-Eb1 histocompatibility 2, class II antigen E beta 0.340
H2-Aa histocompatibility 2, class II antigen A, alpha 0.337
Cybb cytochrome b-245, beta polypeptide 0.322
Cxcl2 chemokine (C-X-C motif) ligand 2 0.306
Irg1 immunoresponsive gene 1 0.303
Rac2 RAS-related C3 botulinum substrate 2 0.297
Mmp8 matrix metallopeptidase 8 0.295
Ccl9 chemokine (C-C motif) ligand 9 0.280
Msr1 macrophage scavenger receptor 1 0.273
Pak1 p21 protein (Cdc42/Rac)-activated kinase 1 0.272
Clec4e C-type lectin domain family 4, member e 0.271
Cxcr2 chemokine (C-X-C motif) receptor 2 0.266
Itgal integrin alpha L 0.256
P2rx7 purinergic receptor P2X, ligand-gated ion channel, 7 0.250
Sele selectin, endothelial cell 0.248
Gm14548 predicted gene 14548 0.246
Has1 hyaluronan synthase1 0.240
Mmp12 matrix metallopeptidase 12 0.234
Clec4d C-type lectin domain family 4, member d 0.231
Hp haptoglobin 0.223
Slfn4 schlafen 4 0.212
S100a8 S100 calcium binding protein A8 (calgranulin A) 0.209
Mmp3 matrix metallopeptidase 3 0.206
Fpr1 formyl peptide receptor 1 0.201
Ear2 eosinophil-associated, ribonuclease A family, member 2 0.197
S100a9 S100 calcium binding protein A9 (calgranulin B) 0.196
Bdkrb1 bradykinin receptor, beta 1 0.185
Cd14 CD14 antigen 0.184
Ch25h cholesterol 25-hydroxylase 0.184
Lrg1 leucine-rich alpha-2-glycoprotein 1 0.183
Cx3cr1 chemokine (C-X3-C) receptor 1 0.179
Chi3l3 chitinase 3-like 3 0.179
Ctsw cathepsin W 0.177
Cd7 CD7 antigen 0.175
Gzmb granzyme B 0.172
Itgam integrin alpha M 0.162
Serpina3n serine (or cysteine) peptidase inhibitor, clade A, member 3N 0.159
Slc10a6 solute carrier family 10 (sodium/bile acid cotransporter family), member 6 0.154
Ifitm6 interferon induced transmembrane protein 6 0.151
Ccl6 chemokine (C-C motif) ligand 6 0.150
Fpr3 formyl peptide receptor 3 0.149
Lilrb3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 0.145
Saa3 serum amyloid A 3 0.139
Gzma granzyme A 0.137
Il1a interleukin 1 alpha 0.135
9430031J16Rik RIKEN cDNA 9430031J16 gene 0.135
Icam1 intercellular adhesion molecule 1 0.131
Cd96 CD96 antigen 0.131
Siglec1 sialic acid binding Ig-like lectin 1, sialoadhesin 0.130
Folr2 folate receptor 2 (fetal) 0.130
Il7r interleukin 7 receptor 0.130
Selplg selectin, platelet (p-selectin) ligand 0.129
Sell selectin, lymphocyte 0.126
Fpr2 formyl peptide receptor 2 0.125
Ubd ubiquitin D 0.124
Itgb2 integrin beta 2 0.114
Cd44 CD44 antigen 0.109
Cd3e CD3 antigen, epsilon polypeptide 0.109
Ccl12 chemokine (C-C motif) ligand 12 0.106
H2-DMa histocompatibility 2, class II, locus DMa 0.104
Il18rap interleukin 18 receptor accessory protein 0.101
Tlr7 toll-like receptor 7 0.101
Jak3 Janus kinase 3 0.101
Klrg1 killer cell lectin-like receptor subfamily G, member 1 0.098
Cxcl13 chemokine (C-X-C motif) ligand 13 0.091
Slpi secretory leukocyte peptidase inhibitor 0.090
Ccl7 chemokine (C-C motif) ligand 7 0.085
Lcn2 lipocalin 2 0.085
H2-Ab1 histocompatibility 2, class II antigen A, beta 1 0.084
Cxcl1 chemokine (C-X-C motif) ligand 1 0.084
Gpr132 G protein-coupled receptor 132 0.082
Tnfrsf9 tumor necrosis factor receptor superfamily, member 9 0.081
Sh2d2a SH2 domain protein 2A 0.081
Ccl17 chemokine (C-C motif) ligand 17 0.081
Ifng interferon gamma 0.080
Myo1f myosin IF 0.080
Cd180 CD180 antigen 0.079
Sfpi1 SFFV proviral integration 1 0.079
Il2rb interleukin 2 receptor, beta chain 0.079
Xcr1 chemokine (C motif) receptor 1 0.076
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Rattus norvegicus
Name Description Probability Func Analog Organism
RT1-DMb RT1 class II, locus DMb 0.485
Il2rg interleukin 2 receptor, gamma 0.423
Ccr5 chemokine (C-C motif) receptor 5 0.202
Tcrb T-cell receptor beta chain 0.178
RT1-Da RT1 class II, locus Da 0.176
RT1-Bb RT1 class II, locus Bb 0.170
Il8rb interleukin 8 receptor, beta 0.137
Ccl4 chemokine (C-C motif) ligand 4 0.119
Cd83 CD83 molecule 0.110
Tyrobp Tyro protein tyrosine kinase binding protein 0.106
Laptm5 lysosomal protein transmembrane 5 0.081
Il1a interleukin 1 alpha 0.079
Csf2rb colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.071
Ccl3 chemokine (C-C motif) ligand 3 0.064
Mefv Mediterranean fever 0.060
Cd4 Cd4 molecule 0.051
Pde6h phosphodiesterase 6H, cGMP-specific, cone, gamma 0.051
Ptprc protein tyrosine phosphatase, receptor type, C 0.050
Ly86 lymphocyte antigen 86 0.048
Cxcl2 chemokine (C-X-C motif) ligand 2 0.045
Cd69 Cd69 molecule 0.043
Cxcl10 chemokine (C-X-C motif) ligand 10 0.043
Pstpip1 proline-serine-threonine phosphatase-interacting protein 1 0.043
Cpa3 carboxypeptidase A3, mast cell 0.039
Arhgdib Rho, GDP dissociation inhibitor (GDI) beta 0.038
Gzmk granzyme K 0.037
Il6 interleukin 6 0.032
St8sia4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 0.031
F2rl1 coagulation factor II (thrombin) receptor-like 1 0.029
Hck hemopoietic cell kinase 0.028
Arl5c ADP-ribosylation factor-like 5C 0.027
Fcgr3a Fc fragment of IgG, low affinity IIIa, receptor 0.026
Cybb cytochrome b-245, beta polypeptide 0.026
Vcan versican 0.022
Gimap5 GTPase, IMAP family member 5 0.022
Olah oleoyl-ACP hydrolase 0.021
Pfkfb2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 0.021
Il9r interleukin 9 receptor 0.020
Reg3g regenerating islet-derived 3 gamma 0.020
Il2rb interleukin 2 receptor, beta 0.020
Cd53 Cd53 molecule 0.018
F2rl2 coagulation factor II (thrombin) receptor-like 2 0.017
Ccl20 chemokine (C-C motif) ligand 20 0.017
Calcrl calcitonin receptor-like 0.017
Ciita class II, major histocompatibility complex, transactivator 0.016
Gabrg1 gamma-aminobutyric acid (GABA) A receptor, gamma 1 0.016
LOC24906 RoBo-1 0.015
Thbd thrombomodulin 0.015
Ptafr platelet-activating factor receptor 0.015
Ccr3 chemokine (C-C motif) receptor 3 0.015
Flt1 FMS-related tyrosine kinase 1 0.014
Cd14 CD14 molecule 0.014
Napsa napsin A aspartic peptidase 0.013
P2ry6 pyrimidinergic receptor P2Y, G-protein coupled, 6 0.013
Edn1 endothelin 1 0.013
Cd8a CD8a molecule 0.013
Col12a1 collagen, type XII, alpha 1 0.012
Kif6 kinesin family member 6 0.012
Fam65b family with sequence similarity 65, member B 0.012
Adam2 ADAM metallopeptidase domain 2 0.012
C5ar1 complement component 5a receptor 1 0.012
Fcnb ficolin B 0.012
Cd44 Cd44 molecule 0.012
RT1-Db1 RT1 class II, locus Db1 0.012
Il2ra interleukin 2 receptor, alpha 0.011
Cd38 CD38 molecule 0.011
Nkg7 natural killer cell group 7 sequence 0.011
Bcl2a1d B-cell leukemia/lymphoma 2 related protein A1d 0.011
Cyp7a1 cytochrome P450, family 7, subfamily a, polypeptide 1 0.011
S1pr2 sphingosine-1-phosphate receptor 2 0.011
Olr1496 olfactory receptor 1496 0.011
Plac8 placenta-specific 8 0.011
Cd37 CD37 molecule 0.011
LOC100364854 similar to RIKEN cDNA A430107P09 gene-like 0.011
Socs3 suppressor of cytokine signaling 3 0.010
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism