IMP
Process View
The network for 't cell differentiation involved in immune response' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
t cell differentiation involved in immune response
The process in which an antigenically naive T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| IL4R | interleukin 4 receptor | 0.979 | |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.781 | |
| LIN9 | lin-9 homolog (C. elegans) | 0.502 | |
| NR0B1 | nuclear receptor subfamily 0, group B, member 1 | 0.448 | |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 0.355 | |
| BCL3 | B-cell CLL/lymphoma 3 | 0.227 | |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 0.167 | |
| NKX2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.150 | |
| RELB | v-rel reticuloendotheliosis viral oncogene homolog B | 0.146 | |
| SIN3A | SIN3 homolog A, transcription regulator (yeast) | 0.136 | |
| PDZD11 | PDZ domain containing 11 | 0.115 | |
| IL2RG | interleukin 2 receptor, gamma | 0.108 | |
| IL23A | interleukin 23, alpha subunit p19 | 0.089 | |
| REL | v-rel reticuloendotheliosis viral oncogene homolog (avian) | 0.081 | |
| IL12B | interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) | 0.078 | |
| RELA | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.063 | |
| NLK | nemo-like kinase | 0.055 | |
| SOCS3 | suppressor of cytokine signaling 3 | 0.055 | |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.053 | |
| RARA | retinoic acid receptor, alpha | 0.052 | |
| TRAF1 | TNF receptor-associated factor 1 | 0.045 | |
| TRAF3 | TNF receptor-associated factor 3 | 0.043 | |
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced | 0.039 | |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.035 | |
| EP300 | E1A binding protein p300 | 0.025 | |
| NCOR2 | nuclear receptor corepressor 2 | 0.024 | |
| TMEM173 | transmembrane protein 173 | 0.022 | |
| IL6R | interleukin 6 receptor | 0.021 | |
| IL1B | interleukin 1, beta | 0.019 | |
| ICAM1 | intercellular adhesion molecule 1 | 0.019 | |
| IL8 | interleukin 8 | 0.017 | |
| INPP5D | inositol polyphosphate-5-phosphatase, 145kDa | 0.017 | |
| IL4 | interleukin 4 | 0.016 | |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.016 | |
| PML | promyelocytic leukemia | 0.015 | |
| TNFRSF9 | tumor necrosis factor receptor superfamily, member 9 | 0.014 | |
| CCR7 | chemokine (C-C motif) receptor 7 | 0.014 | |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.013 | |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 0.011 | |
| PLXND1 | plexin D1 | 0.011 | |
| RB1 | retinoblastoma 1 | 0.010 |
Loading network...
Mus musculus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Nfkb2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 | 0.999 | |
| Tnf | tumor necrosis factor | 0.995 | |
| Stat3 | signal transducer and activator of transcription 3 | 0.979 | |
| Rela | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.960 | |
| Socs1 | suppressor of cytokine signaling 1 | 0.939 | |
| Stat5a | signal transducer and activator of transcription 5A | 0.931 | |
| Csf2rb2 | colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage) | 0.922 | |
| Cd40 | CD40 antigen | 0.908 | |
| Relb | avian reticuloendotheliosis viral (v-rel) oncogene related B | 0.906 | |
| Nfkbia | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.904 | |
| Il6 | interleukin 6 | 0.863 | |
| Gli3 | GLI-Kruppel family member GLI3 | 0.857 | |
| Nfkb1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 | 0.853 | |
| Stat6 | signal transducer and activator of transcription 6 | 0.834 | |
| Zeb1 | zinc finger E-box binding homeobox 1 | 0.824 | |
| Il4ra | interleukin 4 receptor, alpha | 0.820 | |
| Jak2 | Janus kinase 2 | 0.801 | |
| Il10 | interleukin 10 | 0.797 | |
| Batf | basic leucine zipper transcription factor, ATF-like | 0.773 | |
| Tnfaip3 | tumor necrosis factor, alpha-induced protein 3 | 0.768 | |
| Ccl4 | chemokine (C-C motif) ligand 4 | 0.760 | |
| Lef1 | lymphoid enhancer binding factor 1 | 0.737 | |
| Il1r1 | interleukin 1 receptor, type I | 0.716 | |
| Fas | Fas (TNF receptor superfamily member 6) | 0.692 | |
| Gata4 | GATA binding protein 4 | 0.646 | |
| Stat2 | signal transducer and activator of transcription 2 | 0.620 | |
| Lyz2 | lysozyme 2 | 0.613 | |
| Tnfrsf9 | tumor necrosis factor receptor superfamily, member 9 | 0.612 | |
| Pitx1 | paired-like homeodomain transcription factor 1 | 0.591 | |
| Tnfrsf1a | tumor necrosis factor receptor superfamily, member 1a | 0.591 | |
| Runx1 | runt related transcription factor 1 | 0.586 | |
| Foxp3 | forkhead box P3 | 0.581 | |
| Pax2 | paired box gene 2 | 0.567 | |
| Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.561 | |
| Ifng | interferon gamma | 0.553 | |
| Irf4 | interferon regulatory factor 4 | 0.533 | |
| Cd28 | CD28 antigen | 0.524 | |
| Irf9 | interferon regulatory factor 9 | 0.518 | |
| Tbx3 | T-box 3 | 0.517 | |
| Pitx2 | paired-like homeodomain transcription factor 2 | 0.505 | |
| Ikzf1 | IKAROS family zinc finger 1 | 0.497 | |
| Ccl2 | chemokine (C-C motif) ligand 2 | 0.493 | |
| Prrx1 | paired related homeobox 1 | 0.462 | |
| Atxn1 | ataxin 1 | 0.453 | |
| Lepr | leptin receptor | 0.451 | |
| Bcl3 | B-cell leukemia/lymphoma 3 | 0.447 | |
| Il2rb | interleukin 2 receptor, beta chain | 0.431 | |
| Map3k8 | mitogen-activated protein kinase kinase kinase 8 | 0.414 | |
| Icam1 | intercellular adhesion molecule 1 | 0.409 | |
| Stat5b | signal transducer and activator of transcription 5B | 0.395 | |
| Gata6 | GATA binding protein 6 | 0.367 | |
| Traf1 | TNF receptor-associated factor 1 | 0.360 | |
| Jak3 | Janus kinase 3 | 0.359 | |
| Csf2rb | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | 0.332 | |
| Fasl | Fas ligand (TNF superfamily, member 6) | 0.331 | |
| Ccl7 | chemokine (C-C motif) ligand 7 | 0.328 | |
| Irf5 | interferon regulatory factor 5 | 0.321 | |
| Hoxa1 | homeobox A1 | 0.312 | |
| Dll4 | delta-like 4 (Drosophila) | 0.309 | |
| Map3k14 | mitogen-activated protein kinase kinase kinase 14 | 0.307 | |
| Il4 | interleukin 4 | 0.303 | |
| Rxra | retinoid X receptor alpha | 0.301 | |
| Il10ra | interleukin 10 receptor, alpha | 0.301 | |
| Tnfrsf4 | tumor necrosis factor receptor superfamily, member 4 | 0.299 | |
| Foxf1a | forkhead box F1a | 0.295 | |
| Rag1 | recombination activating gene 1 | 0.291 | |
| Bcl6 | B-cell leukemia/lymphoma 6 | 0.288 | |
| Socs3 | suppressor of cytokine signaling 3 | 0.288 | |
| Cxcl2 | chemokine (C-X-C motif) ligand 2 | 0.278 | |
| Icos | inducible T-cell co-stimulator | 0.275 | |
| Ccr1 | chemokine (C-C motif) receptor 1 | 0.272 | |
| Fgfr2 | fibroblast growth factor receptor 2 | 0.257 | |
| Myd88 | myeloid differentiation primary response gene 88 | 0.255 | |
| Tnfrsf1b | tumor necrosis factor receptor superfamily, member 1b | 0.252 | |
| Tnip1 | TNFAIP3 interacting protein 1 | 0.252 | |
| Casp4 | caspase 4, apoptosis-related cysteine peptidase | 0.252 | |
| Ccl12 | chemokine (C-C motif) ligand 12 | 0.245 | |
| Cd86 | CD86 antigen | 0.242 | |
| Fgf10 | fibroblast growth factor 10 | 0.238 | |
| Cish | cytokine inducible SH2-containing protein | 0.231 | |
| Il2rg | interleukin 2 receptor, gamma chain | 0.219 | |
| Sox2 | SRY-box containing gene 2 | 0.215 | |
| Sfpi1 | SFFV proviral integration 1 | 0.210 | |
| Zfpm2 | zinc finger protein, multitype 2 | 0.198 | |
| Batf3 | basic leucine zipper transcription factor, ATF-like 3 | 0.195 | |
| Il27ra | interleukin 27 receptor, alpha | 0.195 | |
| Ccr7 | chemokine (C-C motif) receptor 7 | 0.189 | |
| Prdm1 | PR domain containing 1, with ZNF domain | 0.185 | |
| Shh | sonic hedgehog | 0.180 | |
| Ptpn22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) | 0.179 | |
| Pdcd1 | programmed cell death 1 | 0.171 | |
| Lag3 | lymphocyte-activation gene 3 | 0.169 | |
| Il6st | interleukin 6 signal transducer | 0.168 | |
| Prf1 | perforin 1 (pore forming protein) | 0.162 | |
| Pik3cd | phosphatidylinositol 3-kinase catalytic delta polypeptide | 0.160 | |
| Ccl8 | chemokine (C-C motif) ligand 8 | 0.160 | |
| Cd80 | CD80 antigen | 0.159 | |
| Lta | lymphotoxin A | 0.159 | |
| Cxcl10 | chemokine (C-X-C motif) ligand 10 | 0.152 | |
| Creb1 | cAMP responsive element binding protein 1 | 0.151 |