The network for 'retrograde transport endosome to golgi' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

retrograde transport endosome to golgi

The directed movement of membrane-bounded vesicles from endosomes back to the trans-Golgi network where they are recycled for further rounds of transport.

Homo sapiens
Name Description Probability Func Analog Organism
SNX6 sorting nexin 6 0.977
SNX2 sorting nexin 2 0.926
HSPA1B heat shock 70kDa protein 1B 0.910
SNX9 sorting nexin 9 0.907
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF 0.833
HSPA1A heat shock 70kDa protein 1A 0.776
SLC9A3R1 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 0.671
STX8 syntaxin 8 0.662
ITCH itchy E3 ubiquitin protein ligase homolog (mouse) 0.611
SNX1 sorting nexin 1 0.559
OCRL oculocerebrorenal syndrome of Lowe 0.489
STX4 syntaxin 4 0.460
ADAM15 ADAM metallopeptidase domain 15 0.456
STX7 syntaxin 7 0.443
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 0.382
SNAP23 synaptosomal-associated protein, 23kDa 0.344
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae) 0.315
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.288
MED15 mediator complex subunit 15 0.269
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.253
GCC2 GRIP and coiled-coil domain containing 2 0.236
FNBP1 formin binding protein 1 0.235
ZNF263 zinc finger protein 263 0.230
RAB6A RAB6A, member RAS oncogene family 0.202
DNM2 dynamin 2 0.171
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative) 0.171
BECN1 beclin 1, autophagy related 0.163
STX12 syntaxin 12 0.160
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) 0.148
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila) 0.148
TRIM39 tripartite motif containing 39 0.130
CALCOCO1 calcium binding and coiled-coil domain 1 0.128
RNF11 ring finger protein 11 0.123
TRIM21 tripartite motif containing 21 0.119
SCFD1 sec1 family domain containing 1 0.115
ARF6 ADP-ribosylation factor 6 0.104
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 0.102
KIAA1033 KIAA1033 0.100
BAG1 BCL2-associated athanogene 0.096
VAMP7 vesicle-associated membrane protein 7 0.094
RHAG Rh-associated glycoprotein 0.093
RGMA RGM domain family, member A 0.092
VAMP4 vesicle-associated membrane protein 4 0.091
MIB1 mindbomb homolog 1 (Drosophila) 0.090
ARL4D ADP-ribosylation factor-like 4D 0.088
RAB11FIP2 RAB11 family interacting protein 2 (class I) 0.087
PLEKHJ1 pleckstrin homology domain containing, family J member 1 0.083
SNX33 sorting nexin 33 0.083
SP100 SP100 nuclear antigen 0.083
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha 0.080
MESDC2 mesoderm development candidate 2 0.079
NCK1 NCK adaptor protein 1 0.079
GDI2 GDP dissociation inhibitor 2 0.078
OPTN optineurin 0.077
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) 0.076
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) 0.075
TRIM26 tripartite motif containing 26 0.075
PPP5C protein phosphatase 5, catalytic subunit 0.072
SH3GLB1 SH3-domain GRB2-like endophilin B1 0.072
SYPL1 synaptophysin-like 1 0.071
BET1 blocked early in transport 1 homolog (S. cerevisiae) 0.069
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) 0.068
RAB11FIP1 RAB11 family interacting protein 1 (class I) 0.065
ANKRD28 ankyrin repeat domain 28 0.063
EZR ezrin 0.062
RAB4A RAB4A, member RAS oncogene family 0.061
MAPT microtubule-associated protein tau 0.061
RNF14 ring finger protein 14 0.060
TRIM5 tripartite motif containing 5 0.058
VAC14 Vac14 homolog (S. cerevisiae) 0.053
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18 0.053
RAB1A RAB1A, member RAS oncogene family 0.053
STRN4 striatin, calmodulin binding protein 4 0.051
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 0.051
RIC8A resistance to inhibitors of cholinesterase 8 homolog A (C. elegans) 0.051
TRIM17 tripartite motif containing 17 0.050
GATAD1 GATA zinc finger domain containing 1 0.050
SPTB spectrin, beta, erythrocytic 0.050
MKRN1 makorin ring finger protein 1 0.050
SEC62 SEC62 homolog (S. cerevisiae) 0.050
RABGAP1L RAB GTPase activating protein 1-like 0.049
CCDC53 coiled-coil domain containing 53 0.049
ACTR1B ARP1 actin-related protein 1 homolog B, centractin beta (yeast) 0.049
C12orf23 chromosome 12 open reading frame 23 0.046
WASL Wiskott-Aldrich syndrome-like 0.046
ACTR10 actin-related protein 10 homolog (S. cerevisiae) 0.045
GOSR2 golgi SNAP receptor complex member 2 0.044
TRIM34 tripartite motif containing 34 0.044
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.044
RNF5 ring finger protein 5 0.043
BAG3 BCL2-associated athanogene 3 0.043
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 0.043
USO1 USO1 vesicle docking protein homolog (yeast) 0.042
HMOX2 heme oxygenase (decycling) 2 0.042
CHD3 chromodomain helicase DNA binding protein 3 0.041
GOLGA4 golgin A4 0.041
TXNL4A thioredoxin-like 4A 0.041
BAG2 BCL2-associated athanogene 2 0.041
TRIM43 tripartite motif containing 43 0.041
RAB5A RAB5A, member RAS oncogene family 0.040
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
Syx7 Syntaxin 7 0.076
sqh spaghetti squash 0.033
Rab14 Rab-protein 14 0.030
CG9139 CG9139 gene product from transcript CG9139-RA 0.027
Rab2 Rab-protein 2 0.026
TSG101 tumor suppressor protein 101 0.024
Rab6 Rab-protein 6 0.024
Syb Synaptobrevin 0.023
CG2219 CG2219 gene product from transcript CG2219-RA 0.023
sima similar 0.022
Hrs Hepatocyte growth factor regulated tyrosine kinase substrate 0.021
CG12207 CG12207 gene product from transcript CG12207-RB 0.021
CG7945 CG7945 gene product from transcript CG7945-RC 0.021
Dmn Dynamitin 0.021
CHIP CG5203 gene product from transcript CG5203-RA 0.019
GckIII Germinal centre kinase III 0.019
Vti1 CG3279 gene product from transcript CG3279-RA 0.019
fal falten 0.019
CG3573 CG3573 gene product from transcript CG3573-RA 0.018
membrin CG4780 gene product from transcript CG4780-RA 0.017
CG10158 CG10158 gene product from transcript CG10158-RA 0.017
Crk CG1587 gene product from transcript CG1587-RC 0.017
rnh1 ribonuclease H1 0.017
Mlf Myelodysplasia/myeloid leukemia factor 0.017
CG7222 CG7222 gene product from transcript CG7222-RA 0.016
CG8155 CG8155 gene product from transcript CG8155-RA 0.016
Nsf2 NEM-sensitive fusion protein 2 0.016
Sop2 Suppressor of profilin 2 0.015
CG10103 CG10103 gene product from transcript CG10103-RA 0.015
CG5727 CG5727 gene product from transcript CG5727-RA 0.015
twf twinfilin 0.015
CG15118 CG15118 gene product from transcript CG15118-RC 0.014
didum dilute class unconventional myosin 0.014
CG11247 CG11247 gene product from transcript CG11247-RC 0.014
CG1902 CG1902 gene product from transcript CG1902-RA 0.014
Rheb CG1081 gene product from transcript CG1081-RA 0.014
CG4552 CG4552 gene product from transcript CG4552-RA 0.013
gammaCop gamma-coatomer protein 0.013
Rab-RP3 Rab-related protein 3 0.013
CG11242 CG11242 gene product from transcript CG11242-RA 0.013
betaggt-I beta subunit of type I geranylgeranyl transferase 0.013
Rip11 Rab11 interacting protein 0.013
Dnz1 DNZDHHC/NEW1 zinc finger protein 11 0.013
CG5978 CG5978 gene product from transcript CG5978-RA 0.013
granny-smith granny smith 0.012
CG3529 CG3529 gene product from transcript CG3529-RB 0.012
CG12404 CG12404 gene product from transcript CG12404-RA 0.012
CG14980 CG14980 gene product from transcript CG14980-RB 0.012
Snx6 CG8282 gene product from transcript CG8282-RA 0.012
CG15099 CG15099 gene product from transcript CG15099-RA 0.012
CG30392 CG30392 gene product from transcript CG30392-RA 0.012
CG5168 CG5168 gene product from transcript CG5168-RB 0.012
CG1233 CG1233 gene product from transcript CG1233-RB 0.012
CG5604 CG5604 gene product from transcript CG5604-RA 0.012
DnaJ-H DnaJ homolog 0.012
Syx17 Syntaxin 17 0.012
CG5938 CG5938 gene product from transcript CG5938-RD 0.012
Dhod Dihydroorotate dehydrogenase 0.012
Snap24 Synapse protein 24 0.011
CG9795 CG9795 gene product from transcript CG9795-RD 0.011
nudE CG8104 gene product from transcript CG8104-RB 0.011
CG14782 CG14782 gene product from transcript CG14782-RA 0.011
CG3356 CG3356 gene product from transcript CG3356-RA 0.011
Gap69C GTPase-activating protein 69C 0.011
Dlic Dynein light intermediate chain 0.011
DnaJ-1 DnaJ-like-1 0.011
CG7158 CG7158 gene product from transcript CG7158-RA 0.011
CG12024 CG12024 gene product from transcript CG12024-RA 0.011
CG17292 CG17292 gene product from transcript CG17292-RB 0.011
deltaCOP delta-coatomer protein 0.011
prel preli-like 0.011
UBL3 CG9038 gene product from transcript CG9038-RC 0.011
Graf CG8948 gene product from transcript CG8948-RB 0.011
Vhl von Hippel-Lindau 0.010
alpha-Man-IIb CG4606 gene product from transcript CG4606-RA 0.010
CG7927 CG7927 gene product from transcript CG7927-RA 0.010
CG5555 CG5555 gene product from transcript CG5555-RA 0.010
CG8735 CG8735 gene product from transcript CG8735-RA 0.010
CG9393 CG9393 gene product from transcript CG9393-RA 0.010
CG9855 CG9855 gene product from transcript CG9855-RA 0.010
Hmgcr HMG Coenzyme A reductase 0.010
f-cup flyers-cup 0.010
Kap3 Kinesin associated protein 3 0.010
Hsc70-3 Heat shock protein cognate 3 0.010
Clc Clathrin light chain 0.010
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Mus musculus
Name Description Probability Func Analog Organism
Vps35 vacuolar protein sorting 35 0.999
Vps29 vacuolar protein sorting 29 (S. pombe) 0.990
Klc1 kinesin light chain 1 0.757
Stx12 syntaxin 12 0.643
Vps26a vacuolar protein sorting 26 homolog A (yeast) 0.558
Bicd2 bicaudal D homolog 2 (Drosophila) 0.514
5033414D02Rik RIKEN cDNA 5033414D02 gene 0.426
Stx7 syntaxin 7 0.400
Ccdc64 coiled-coil domain containing 64 0.362
Rab1 RAB1, member RAS oncogene family 0.327
Dscr3 Down syndrome critical region gene 3 0.321
Snx6 sorting nexin 6 0.255
Chmp2b chromatin modifying protein 2B 0.235
Snx2 sorting nexin 2 0.198
Arl8b ADP-ribosylation factor-like 8B 0.190
Spna2 spectrin alpha 2 0.189
Nek9 NIMA (never in mitosis gene a)-related expressed kinase 9 0.175
Arf5 ADP-ribosylation factor 5 0.162
Fam96a family with sequence similarity 96, member A 0.160
Ppl periplakin 0.153
Rap1b RAS related protein 1b 0.141
Vamp3 vesicle-associated membrane protein 3 0.136
Add1 adducin 1 (alpha) 0.135
Glg1 golgi apparatus protein 1 0.133
Dync1i2 dynein cytoplasmic 1 intermediate chain 2 0.132
Klraq1 KLRAQ motif containing 1 0.131
Mobkl3 MOB1, Mps One Binder kinase activator-like 3 (yeast) 0.130
Wsb2 WD repeat and SOCS box-containing 2 0.129
Txndc17 thioredoxin domain containing 17 0.122
Cldn3 claudin 3 0.121
Anapc2 anaphase promoting complex subunit 2 0.118
Rragc Ras-related GTP binding C 0.117
Prkar1a protein kinase, cAMP dependent regulatory, type I, alpha 0.116
Vps26b vacuolar protein sorting 26 homolog B (yeast) 0.115
Arf6 ADP-ribosylation factor 6 0.114
Nrbp1 nuclear receptor binding protein 1 0.113
Asah1 N-acylsphingosine amidohydrolase 1 0.111
Ndel1 nuclear distribution gene E-like homolog 1 (A. nidulans) 0.111
Git1 G protein-coupled receptor kinase-interactor 1 0.109
Csnk1g2 casein kinase 1, gamma 2 0.105
Vps18 vacuolar protein sorting 18 (yeast) 0.103
Pi4kb phosphatidylinositol 4-kinase, catalytic, beta polypeptide 0.100
Clstn1 calsyntenin 1 0.099
Stxbp3a syntaxin binding protein 3A 0.098
Cltc clathrin, heavy polypeptide (Hc) 0.095
Rnf115 ring finger protein 115 0.094
Sec22b SEC22 vesicle trafficking protein homolog B (S. cerevisiae) 0.094
Ywhah tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide 0.091
Nptn neuroplastin 0.088
Lamp2 lysosomal-associated membrane protein 2 0.088
Ap1m1 adaptor-related protein complex AP-1, mu subunit 1 0.086
Tmem184b transmembrane protein 184b 0.080
Psmd3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 0.079
Snx1 sorting nexin 1 0.078
Mprip myosin phosphatase Rho interacting protein 0.078
Dctn1 dynactin 1 0.077
Fkbp1a FK506 binding protein 1a 0.077
Ypel3 yippee-like 3 (Drosophila) 0.076
Picalm phosphatidylinositol binding clathrin assembly protein 0.075
Unc50 unc-50 homolog (C. elegans) 0.074
Slc7a5 solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 0.074
Snx12 sorting nexin 12 0.074
Glod4 glyoxalase domain containing 4 0.073
Golga2 golgi autoantigen, golgin subfamily a, 2 0.073
Ctdspl CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like 0.072
Gdi2 guanosine diphosphate (GDP) dissociation inhibitor 2 0.071
Tmem30a transmembrane protein 30A 0.070
Dstn destrin 0.069
Atg13 ATG13 autophagy related 13 homolog (S. cerevisiae) 0.069
Adam9 a disintegrin and metallopeptidase domain 9 (meltrin gamma) 0.069
Dctn2 dynactin 2 0.068
Hpcal1 hippocalcin-like 1 0.068
Zfp740 zinc finger protein 740 0.068
Capza2 capping protein (actin filament) muscle Z-line, alpha 2 0.068
Dync1h1 dynein cytoplasmic 1 heavy chain 1 0.067
Nrbf2 nuclear receptor binding factor 2 0.066
Cadps2 Ca2+-dependent activator protein for secretion 2 0.065
Rala v-ral simian leukemia viral oncogene homolog A (ras related) 0.065
Rab18 RAB18, member RAS oncogene family 0.064
Psmd10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 0.064
Rab5a RAB5A, member RAS oncogene family 0.063
Rab24 RAB24, member RAS oncogene family 0.061
Sh3glb1 SH3-domain GRB2-like B1 (endophilin) 0.061
Rac1 RAS-related C3 botulinum substrate 1 0.061
Gosr1 golgi SNAP receptor complex member 1 0.060
Spns1 spinster homolog 1 (Drosophila) 0.059
Tmem9b TMEM9 domain family, member B 0.059
Abtb1 ankyrin repeat and BTB (POZ) domain containing 1 0.059
Pbx2 pre B-cell leukemia transcription factor 2 0.058
Ankrd46 ankyrin repeat domain 46 0.057
Egln2 EGL nine homolog 2 (C. elegans) 0.057
Acot9 acyl-CoA thioesterase 9 0.057
Poldip3 polymerase (DNA-directed), delta interacting protein 3 0.057
Pacs2 phosphofurin acidic cluster sorting protein 2 0.056
Ube2v1 ubiquitin-conjugating enzyme E2 variant 1 0.056
Chmp1b chromatin modifying protein 1B 0.056
Fam50a family with sequence similarity 50, member A 0.056
Ilk integrin linked kinase 0.056
Selk selenoprotein K 0.056
Plcg2 phospholipase C, gamma 2 0.055
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
VPS17 Vps17p 0.992
VPS5 Vps5p 0.983
YKT6 Ykt6p 0.979
VPS51 Vps51p 0.905
TLG2 Tlg2p 0.868
GOS1 Gos1p 0.857
VPS35 Vps35p 0.854
SFT1 Sft1p 0.729
SED5 Sed5p 0.713
YPT6 Ypt6p 0.682
PEP8 Pep8p 0.659
TLG1 Tlg1p 0.550
YIP3 Yip3p 0.511
RIC1 Ric1p 0.502
VPS29 Vps29p 0.500
TRS65 Trs65p 0.477
YPT52 Ypt52p 0.379
VPS52 Vps52p 0.365
SNX4 Snx4p 0.355
APM2 Apm2p 0.325
TRS130 Trs130p 0.281
BET3 Bet3p 0.271
VPS53 Vps53p 0.254
ATG27 Atg27p 0.254
BET5 Bet5p 0.253
SYS1 Sys1p 0.242
YPT1 Ypt1p 0.216
YPT10 Ypt10p 0.215
VAM6 Vam6p 0.206
VPS45 Vps45p 0.205
YKL023W hypothetical protein 0.180
PEP1 Pep1p 0.176
PEP12 Pep12p 0.162
SLY1 Sly1p 0.158
SEC15 Sec15p 0.154
VPS38 Vps38p 0.139
MVP1 Mvp1p 0.124
COG3 Cog3p 0.121
ENT3 Ent3p 0.118
RER1 Rer1p 0.098
COG6 Cog6p 0.094
APL5 Apl5p 0.094
YPT31 Ypt31p 0.093
YIP4 Yip4p 0.092
SKI3 Ski3p 0.091
CHC1 Chc1p 0.090
YPT7 Ypt7p 0.088
YPT35 Ypt35p 0.087
VPS30 Vps30p 0.083
VPS54 Vps54p 0.083
MTC4 Mtc4p 0.083
SYN8 Syn8p 0.083
VTA1 Vta1p 0.078
COG7 Cog7p 0.076
VPS3 Vps3p 0.073
VPS41 Vps41p 0.072
SEC10 Sec10p 0.071
SEC4 Sec4p 0.070
BTN2 Btn2p 0.065
VAM3 Vam3p 0.063
STI1 Sti1p 0.063
ATG4 Atg4p 0.061
APL4 Apl4p 0.059
CPR6 Cpr6p 0.059
SWC7 Swc7p 0.058
SEC17 Sec17p 0.057
GEA2 Gea2p 0.057
SEC22 Sec22p 0.054
ARF2 Arf2p 0.049
RKR1 Rkr1p 0.049
YIP1 Yip1p 0.049
SRD1 Srd1p 0.048
ARP10 Arp10p 0.048
NPR2 Npr2p 0.048
YMR1 Ymr1p 0.048
MDR1 Mdr1p 0.047
UFD1 Ufd1p 0.045
VPS16 Vps16p 0.044
APL6 Apl6p 0.044
HDA2 Hda2p 0.043
BCH2 Bch2p 0.043
YOS9 Yos9p 0.042
TRS85 Trs85p 0.041
NPL4 Npl4p 0.041
GYP6 Gyp6p 0.040
YOR111W hypothetical protein 0.040
YLR264C-A hypothetical protein 0.040
YOL038C-A hypothetical protein 0.040
URA3 Ura3p 0.040
LEU2 Leu2p 0.039
YLR162W hypothetical protein 0.038
CHS5 Chs5p 0.038
GNA1 Gna1p 0.037
VTI1 Vti1p 0.035
VPS27 Vps27p 0.035
YPT11 Ypt11p 0.034
YGR205W hypothetical protein 0.034
BET1 Bet1p 0.033
ATG21 Atg21p 0.032
LDB18 Ldb18p 0.032