IMP
Process View
The network for 'interleukin 1 beta production' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
interleukin 1 beta production
The appearance of interleukin-1 beta due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| NLRC4 | NLR family, CARD domain containing 4 | 0.991 | |
| PYCARD | PYD and CARD domain containing | 0.858 | |
| HP | haptoglobin | 0.728 | |
| IKBKG | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma | 0.703 | |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.700 | |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) | 0.610 | |
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta | 0.524 | |
| SNTB2 | syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) | 0.469 | |
| CCL4 | chemokine (C-C motif) ligand 4 | 0.421 | |
| SMAD2 | SMAD family member 2 | 0.329 | |
| APOC1 | apolipoprotein C-I | 0.302 | |
| ELANE | elastase, neutrophil expressed | 0.270 | |
| NKG7 | natural killer cell group 7 sequence | 0.247 | |
| HSPB8 | heat shock 22kDa protein 8 | 0.222 | |
| PRF1 | perforin 1 (pore forming protein) | 0.214 | |
| GNLY | granulysin | 0.181 | |
| FZD1 | frizzled homolog 1 (Drosophila) | 0.169 | |
| MPO | myeloperoxidase | 0.151 | |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | 0.149 | |
| CCR7 | chemokine (C-C motif) receptor 7 | 0.139 | |
| APOC3 | apolipoprotein C-III | 0.138 | |
| A2M | alpha-2-macroglobulin | 0.130 | |
| IL1R1 | interleukin 1 receptor, type I | 0.124 | |
| CTSG | cathepsin G | 0.121 | |
| IDE | insulin-degrading enzyme | 0.109 | |
| SOCS3 | suppressor of cytokine signaling 3 | 0.096 | |
| ARRB1 | arrestin, beta 1 | 0.089 | |
| IL7R | interleukin 7 receptor | 0.085 | |
| GPR171 | G protein-coupled receptor 171 | 0.083 | |
| CST7 | cystatin F (leukocystatin) | 0.080 | |
| ALB | albumin | 0.077 | |
| IFNGR1 | interferon gamma receptor 1 | 0.077 | |
| IL1RN | interleukin 1 receptor antagonist | 0.073 | |
| IL2RB | interleukin 2 receptor, beta | 0.072 | |
| CD3D | CD3d molecule, delta (CD3-TCR complex) | 0.072 | |
| PYDC2 | pyrin domain containing 2 | 0.068 | |
| GPR65 | G protein-coupled receptor 65 | 0.065 | |
| LCAT | lecithin-cholesterol acyltransferase | 0.065 | |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.062 | |
| SQSTM1 | sequestosome 1 | 0.061 | |
| AZU1 | azurocidin 1 | 0.054 | |
| LCP2 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) | 0.054 | |
| IL18RAP | interleukin 18 receptor accessory protein | 0.054 | |
| EGR2 | early growth response 2 | 0.050 | |
| CD8A | CD8a molecule | 0.046 | |
| GBP1 | guanylate binding protein 1, interferon-inducible | 0.045 | |
| SOCS1 | suppressor of cytokine signaling 1 | 0.045 | |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.044 | |
| CFL1 | cofilin 1 (non-muscle) | 0.044 | |
| SRGN | serglycin | 0.044 | |
| CLEC4G | C-type lectin domain family 4, member G | 0.042 | |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.042 | |
| CCL19 | chemokine (C-C motif) ligand 19 | 0.042 | |
| PRTN3 | proteinase 3 | 0.041 | |
| ITK | IL2-inducible T-cell kinase | 0.038 | |
| BAG3 | BCL2-associated athanogene 3 | 0.038 | |
| RNASE3 | ribonuclease, RNase A family, 3 | 0.038 | |
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 | 0.037 | |
| CDC37 | cell division cycle 37 homolog (S. cerevisiae) | 0.036 | |
| ATM | ataxia telangiectasia mutated | 0.035 | |
| BTN3A1 | butyrophilin, subfamily 3, member A1 | 0.035 | |
| IRF8 | interferon regulatory factor 8 | 0.035 | |
| SP100 | SP100 nuclear antigen | 0.034 | |
| TARP | TCR gamma alternate reading frame protein | 0.034 | |
| CARD16 | caspase recruitment domain family, member 16 | 0.033 | |
| MMP9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | 0.033 | |
| STAT4 | signal transducer and activator of transcription 4 | 0.033 | |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 | 0.032 | |
| KLRD1 | killer cell lectin-like receptor subfamily D, member 1 | 0.031 | |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | 0.030 | |
| ARHGAP25 | Rho GTPase activating protein 25 | 0.029 | |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.029 | |
| TRIM38 | tripartite motif containing 38 | 0.028 | |
| BCL2A1 | BCL2-related protein A1 | 0.028 | |
| APOA2 | apolipoprotein A-II | 0.027 | |
| JAK3 | Janus kinase 3 | 0.027 | |
| IFNG | interferon, gamma | 0.027 | |
| IL18 | interleukin 18 (interferon-gamma-inducing factor) | 0.027 | |
| CD3G | CD3g molecule, gamma (CD3-TCR complex) | 0.026 | |
| CD48 | CD48 molecule | 0.026 | |
| GSK3B | glycogen synthase kinase 3 beta | 0.026 | |
| KLRK1 | killer cell lectin-like receptor subfamily K, member 1 | 0.025 | |
| C2orf18 | chromosome 2 open reading frame 18 | 0.025 | |
| CTSW | cathepsin W | 0.025 | |
| CPA3 | carboxypeptidase A3 (mast cell) | 0.024 | |
| HDC | histidine decarboxylase | 0.024 | |
| TRIM22 | tripartite motif containing 22 | 0.024 | |
| IGSF6 | immunoglobulin superfamily, member 6 | 0.023 | |
| IGJ | immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides | 0.023 | |
| TNFRSF10C | tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain | 0.023 | |
| PGLYRP1 | peptidoglycan recognition protein 1 | 0.023 | |
| TNIP2 | TNFAIP3 interacting protein 2 | 0.023 | |
| LTF | lactotransferrin | 0.022 | |
| CLEC2B | C-type lectin domain family 2, member B | 0.022 | |
| EMR1 | egf-like module containing, mucin-like, hormone receptor-like 1 | 0.022 | |
| TRAF3IP3 | TRAF3 interacting protein 3 | 0.022 | |
| SF3B4 | splicing factor 3b, subunit 4, 49kDa | 0.022 | |
| PVRIG | poliovirus receptor related immunoglobulin domain containing | 0.022 | |
| C1QA | complement component 1, q subcomponent, A chain | 0.022 | |
| GPR18 | G protein-coupled receptor 18 | 0.022 |
Loading network...
Mus musculus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Casp4 | caspase 4, apoptosis-related cysteine peptidase | 0.993 | |
| Casp1 | caspase 1 | 0.991 | |
| Ccr1 | chemokine (C-C motif) receptor 1 | 0.951 | |
| Pax2 | paired box gene 2 | 0.921 | |
| Il1b | interleukin 1 beta | 0.908 | |
| Pycard | PYD and CARD domain containing | 0.885 | |
| Gbp5 | guanylate binding protein 5 | 0.797 | |
| Otx2 | orthodenticle homolog 2 (Drosophila) | 0.722 | |
| Chrna3 | cholinergic receptor, nicotinic, alpha polypeptide 3 | 0.682 | |
| Socs1 | suppressor of cytokine signaling 1 | 0.673 | |
| Chrnb2 | cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal) | 0.549 | |
| H2-K1 | histocompatibility 2, K1, K region | 0.539 | |
| Mndal | myeloid nuclear differentiation antigen like | 0.528 | |
| Lhx1 | LIM homeobox protein 1 | 0.506 | |
| Emx2 | empty spiracles homolog 2 (Drosophila) | 0.472 | |
| Irf1 | interferon regulatory factor 1 | 0.457 | |
| Ccl3 | chemokine (C-C motif) ligand 3 | 0.387 | |
| Ifngr1 | interferon gamma receptor 1 | 0.379 | |
| Ccl2 | chemokine (C-C motif) ligand 2 | 0.348 | |
| Has1 | hyaluronan synthase1 | 0.342 | |
| Ccr2 | chemokine (C-C motif) receptor 2 | 0.335 | |
| Klrk1 | killer cell lectin-like receptor subfamily K, member 1 | 0.321 | |
| Cd44 | CD44 antigen | 0.276 | |
| B2m | beta-2 microglobulin | 0.240 | |
| Nr5a1 | nuclear receptor subfamily 5, group A, member 1 | 0.230 | |
| Itgax | integrin alpha X | 0.220 | |
| Nkx2-3 | NK2 transcription factor related, locus 3 (Drosophila) | 0.219 | |
| Ret | ret proto-oncogene | 0.210 | |
| Ctsw | cathepsin W | 0.198 | |
| Ccl8 | chemokine (C-C motif) ligand 8 | 0.190 | |
| Birc3 | baculoviral IAP repeat-containing 3 | 0.182 | |
| Gpr33 | G protein-coupled receptor 33 | 0.178 | |
| Dkk1 | dickkopf homolog 1 (Xenopus laevis) | 0.173 | |
| Klrg1 | killer cell lectin-like receptor subfamily G, member 1 | 0.172 | |
| H2-Q7 | histocompatibility 2, Q region locus 7 | 0.169 | |
| Selp | selectin, platelet | 0.164 | |
| Gpr132 | G protein-coupled receptor 132 | 0.153 | |
| Meox1 | mesenchyme homeobox 1 | 0.152 | |
| Aim2 | absent in melanoma 2 | 0.150 | |
| Cd40 | CD40 antigen | 0.140 | |
| Mybph | myosin binding protein H | 0.132 | |
| Pou4f3 | POU domain, class 4, transcription factor 3 | 0.130 | |
| C3ar1 | complement component 3a receptor 1 | 0.128 | |
| Ccr5 | chemokine (C-C motif) receptor 5 | 0.123 | |
| Cryab | crystallin, alpha B | 0.121 | |
| Gfra2 | glial cell line derived neurotrophic factor family receptor alpha 2 | 0.119 | |
| Lhx3 | LIM homeobox protein 3 | 0.114 | |
| Neurog2 | neurogenin 2 | 0.108 | |
| Ccl22 | chemokine (C-C motif) ligand 22 | 0.107 | |
| 2210010C04Rik | RIKEN cDNA 2210010C04 gene | 0.105 | |
| Klrd1 | killer cell lectin-like receptor, subfamily D, member 1 | 0.105 | |
| Rapsn | receptor-associated protein of the synapse | 0.104 | |
| Chrnb4 | cholinergic receptor, nicotinic, beta polypeptide 4 | 0.103 | |
| Grid1 | glutamate receptor, ionotropic, delta 1 | 0.102 | |
| Folr2 | folate receptor 2 (fetal) | 0.102 | |
| Wnt4 | wingless-related MMTV integration site 4 | 0.097 | |
| Ubd | ubiquitin D | 0.093 | |
| Sh2d2a | SH2 domain protein 2A | 0.092 | |
| Il1a | interleukin 1 alpha | 0.092 | |
| Tnf | tumor necrosis factor | 0.090 | |
| Ptprc | protein tyrosine phosphatase, receptor type, C | 0.088 | |
| Il27ra | interleukin 27 receptor, alpha | 0.088 | |
| Osr1 | odd-skipped related 1 (Drosophila) | 0.088 | |
| Nkg7 | natural killer cell group 7 sequence | 0.088 | |
| Pax1 | paired box gene 1 | 0.086 | |
| Pou3f2 | POU domain, class 3, transcription factor 2 | 0.084 | |
| Drd2 | dopamine receptor D2 | 0.083 | |
| Gdnf | glial cell line derived neurotrophic factor | 0.082 | |
| En1 | engrailed 1 | 0.082 | |
| Spib | Spi-B transcription factor (Spi-1/PU.1 related) | 0.081 | |
| Il12rb2 | interleukin 12 receptor, beta 2 | 0.081 | |
| Pitx3 | paired-like homeodomain transcription factor 3 | 0.075 | |
| Dact1 | dapper homolog 1, antagonist of beta-catenin (xenopus) | 0.075 | |
| Ascl1 | achaete-scute complex homolog 1 (Drosophila) | 0.074 | |
| Kcne1l | potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene | 0.073 | |
| Irg1 | immunoresponsive gene 1 | 0.073 | |
| Cxcl13 | chemokine (C-X-C motif) ligand 13 | 0.071 | |
| Il18 | interleukin 18 | 0.071 | |
| Csf3r | colony stimulating factor 3 receptor (granulocyte) | 0.071 | |
| Klrb1b | killer cell lectin-like receptor subfamily B member 1B | 0.069 | |
| AI607873 | expressed sequence AI607873 | 0.069 | |
| Chrne | cholinergic receptor, nicotinic, epsilon polypeptide | 0.068 | |
| Adra2b | adrenergic receptor, alpha 2b | 0.067 | |
| Xcl1 | chemokine (C motif) ligand 1 | 0.067 | |
| Cx3cr1 | chemokine (C-X3-C) receptor 1 | 0.064 | |
| Nlrp3 | NLR family, pyrin domain containing 3 | 0.064 | |
| Blk | B lymphoid kinase | 0.064 | |
| Fasl | Fas ligand (TNF superfamily, member 6) | 0.064 | |
| H2-T18 | histocompatibility 2, T region locus 18 | 0.062 | |
| Ccr4 | chemokine (C-C motif) receptor 4 | 0.061 | |
| Pax8 | paired box gene 8 | 0.060 | |
| Ccl7 | chemokine (C-C motif) ligand 7 | 0.060 | |
| Gfra1 | glial cell line derived neurotrophic factor family receptor alpha 1 | 0.059 | |
| Krt86 | keratin 86 | 0.059 | |
| Slamf8 | SLAM family member 8 | 0.058 | |
| Mmp12 | matrix metallopeptidase 12 | 0.058 | |
| Myod1 | myogenic differentiation 1 | 0.058 | |
| Gpr50 | G-protein-coupled receptor 50 | 0.057 | |
| Madcam1 | mucosal vascular addressin cell adhesion molecule 1 | 0.057 | |
| Cd7 | CD7 antigen | 0.057 |