The network for 'behavioral defense response' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

behavioral defense response

A behavioral response seeking to protect an organism from an a perceived external threat to that organism.

Name Description Probability Func Analog Organism
BCL2L1 BCL2-like 1 1.000
BAX BCL2-associated X protein 0.727
MPDZ multiple PDZ domain protein 0.672
HDAC4 histone deacetylase 4 0.600
CRHR1 corticotropin releasing hormone receptor 1 0.558
AMBRA1 autophagy/beclin-1 regulator 1 0.519
BAK1 BCL2-antagonist/killer 1 0.517
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 0.419
BECN1 beclin 1, autophagy related 0.377
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.355
DLG4 discs, large homolog 4 (Drosophila) 0.335
BAD BCL2-associated agonist of cell death 0.313
RAI1 retinoic acid induced 1 0.280
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 0.250
RPL18A ribosomal protein L18a 0.246
ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9) 0.216
MYLK2 myosin light chain kinase 2 0.203
TP53BP2 tumor protein p53 binding protein, 2 0.201
KCNA1 potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) 0.174
BID BH3 interacting domain death agonist 0.170
FKBP8 FK506 binding protein 8, 38kDa 0.145
BIK BCL2-interacting killer (apoptosis-inducing) 0.135
MCL1 myeloid cell leukemia sequence 1 (BCL2-related) 0.119
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2 0.105
KIFC2 kinesin family member C2 0.081
GLO1 glyoxalase I 0.076
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 0.071
VDAC2 voltage-dependent anion channel 2 0.070
HIPK2 homeodomain interacting protein kinase 2 0.066
DDX24 DEAD (Asp-Glu-Ala-Asp) box polypeptide 24 0.064
UBXN2A UBX domain protein 2A 0.060
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 0.060
LPL lipoprotein lipase 0.059
WDR20 WD repeat domain 20 0.059
DUSP23 dual specificity phosphatase 23 0.058
CAMK2B calcium/calmodulin-dependent protein kinase II beta 0.055
BBC3 BCL2 binding component 3 0.054
NIPSNAP1 nipsnap homolog 1 (C. elegans) 0.047
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 0.047
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 0.047
DLGAP1 discs, large (Drosophila) homolog-associated protein 1 0.044
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.044
FHL1 four and a half LIM domains 1 0.042
ZNF784 zinc finger protein 784 0.042
MAPK8 mitogen-activated protein kinase 8 0.041
HDAC9 histone deacetylase 9 0.040
EP300 E1A binding protein p300 0.040
ASCC2 activating signal cointegrator 1 complex subunit 2 0.038
NDUFB3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa 0.037
FSTL4 follistatin-like 4 0.036
KCNA4 potassium voltage-gated channel, shaker-related subfamily, member 4 0.035
PRDX1 peroxiredoxin 1 0.035
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.034
NAF1 nuclear assembly factor 1 homolog (S. cerevisiae) 0.034
RNF144B ring finger protein 144B 0.033
CRMP1 collapsin response mediator protein 1 0.031
PPP1R9B protein phosphatase 1, regulatory (inhibitor) subunit 9B 0.031
BCL2L2 BCL2-like 2 0.031
DAPK1 death-associated protein kinase 1 0.031
UVRAG UV radiation resistance associated gene 0.030
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha 0.030
ACTL6B actin-like 6B 0.029
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 0.027
DLGAP2 discs, large (Drosophila) homolog-associated protein 2 0.026
RAD23B RAD23 homolog B (S. cerevisiae) 0.026
MLH1 mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) 0.025
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 0.025
GRIA1 glutamate receptor, ionotropic, AMPA 1 0.024
OR2AG1 olfactory receptor, family 2, subfamily AG, member 1 0.024
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C 0.024
ERBB4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 0.023
PLXNA3 plexin A3 0.023
AFF2 AF4/FMR2 family, member 2 0.023
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) 0.022
CADM3 cell adhesion molecule 3 0.022
VDAC1 voltage-dependent anion channel 1 0.022
DBN1 drebrin 1 0.022
METAP1 methionyl aminopeptidase 1 0.022
CA10 carbonic anhydrase X 0.021
GRIA4 glutamate receptor, ionotrophic, AMPA 4 0.021
SPNS1 spinster homolog 1 (Drosophila) 0.021
EEA1 early endosome antigen 1 0.021
HRK harakiri, BCL2 interacting protein (contains only BH3 domain) 0.020
SOD1 superoxide dismutase 1, soluble 0.020
GRIK1 glutamate receptor, ionotropic, kainate 1 0.020
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2 0.019
EMX1 empty spiracles homeobox 1 0.019
HK1 hexokinase 1 0.019
WDR48 WD repeat domain 48 0.019
SSTR3 somatostatin receptor 3 0.019
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 0.019
NLGN1 neuroligin 1 0.019
GRIA2 glutamate receptor, ionotropic, AMPA 2 0.018
MAPK1 mitogen-activated protein kinase 1 0.018
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 0.018
RIBC2 RIB43A domain with coiled-coils 2 0.018
KCNJ4 potassium inwardly-rectifying channel, subfamily J, member 4 0.018
CCKBR cholecystokinin B receptor 0.017
DLG2 discs, large homolog 2 (Drosophila) 0.017
ACAT2 acetyl-CoA acetyltransferase 2 0.017
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Emx1 empty spiracles homolog 1 (Drosophila) 0.900
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.881
Gabrb2 gamma-aminobutyric acid (GABA) A receptor, subunit beta 2 0.748
Neurod1 neurogenic differentiation 1 0.455
Gabrb3 gamma-aminobutyric acid (GABA) A receptor, subunit beta 3 0.422
Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 0.421
Gad2 glutamic acid decarboxylase 2 0.392
Grid1 glutamate receptor, ionotropic, delta 1 0.310
Grin2a glutamate receptor, ionotropic, NMDA2A (epsilon 1) 0.287
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.240
Kiss1 KiSS-1 metastasis-suppressor 0.236
Shh sonic hedgehog 0.230
Kcnj3 potassium inwardly-rectifying channel, subfamily J, member 3 0.220
Dab1 disabled homolog 1 (Drosophila) 0.214
Gabra2 gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2 0.195
Shc3 src homology 2 domain-containing transforming protein C3 0.191
Lep leptin 0.168
Cckbr cholecystokinin B receptor 0.164
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.164
Cacng2 calcium channel, voltage-dependent, gamma subunit 2 0.158
Adra2c adrenergic receptor, alpha 2c 0.153
Gabra1 gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1 0.148
Bcl2 B-cell leukemia/lymphoma 2 0.147
Bax BCL2-associated X protein 0.111
Hand1 heart and neural crest derivatives expressed transcript 1 0.110
Oprl1 opioid receptor-like 1 0.101
Adrb1 adrenergic receptor, beta 1 0.098
Htr1a 5-hydroxytryptamine (serotonin) receptor 1A 0.094
Dlg4 discs, large homolog 4 (Drosophila) 0.091
Neurod4 neurogenic differentiation 4 0.090
Pax6 paired box gene 6 0.090
Cntn4 contactin 4 0.086
Grm8 glutamate receptor, metabotropic 8 0.085
Slc12a5 solute carrier family 12, member 5 0.085
Dcx doublecortin 0.082
Neurog2 neurogenin 2 0.081
Pnpla2 patatin-like phospholipase domain containing 2 0.079
Sstr4 somatostatin receptor 4 0.078
Kcnj11 potassium inwardly rectifying channel, subfamily J, member 11 0.076
Gabrg2 gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2 0.072
Scn1a sodium channel, voltage-gated, type I, alpha 0.071
Bsn bassoon 0.069
Zfpm2 zinc finger protein, multitype 2 0.067
Prph2 peripherin 2 0.064
Syn2 synapsin II 0.063
Gabrb1 gamma-aminobutyric acid (GABA) A receptor, subunit beta 1 0.061
Cux2 cut-like homeobox 2 0.060
Oprk1 opioid receptor, kappa 1 0.060
Nxph1 neurexophilin 1 0.059
Otx2 orthodenticle homolog 2 (Drosophila) 0.059
Celf4 CUGBP, Elav-like family member 4 0.058
Amelx amelogenin X chromosome 0.057
Cdh10 cadherin 10 0.057
Npas1 neuronal PAS domain protein 1 0.056
St8sia3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 0.056
Mecom MDS1 and EVI1 complex locus 0.055
Cacnb2 calcium channel, voltage-dependent, beta 2 subunit 0.055
Hdac4 histone deacetylase 4 0.053
Dlgap1 discs, large (Drosophila) homolog-associated protein 1 0.052
Pdx1 pancreatic and duodenal homeobox 1 0.051
Atp2b2 ATPase, Ca++ transporting, plasma membrane 2 0.051
Grm1 glutamate receptor, metabotropic 1 0.050
Alx3 aristaless-like homeobox 3 0.049
Camk2a calcium/calmodulin-dependent protein kinase II alpha 0.049
Calb1 calbindin 1 0.048
Lhx6 LIM homeobox protein 6 0.048
Mef2c myocyte enhancer factor 2C 0.047
Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 0.047
Ptf1a pancreas specific transcription factor, 1a 0.047
Grik4 glutamate receptor, ionotropic, kainate 4 0.046
Gabra5 gamma-aminobutyric acid (GABA) A receptor, subunit alpha 5 0.046
Nxph2 neurexophilin 2 0.045
Tac2 tachykinin 2 0.045
Htr4 5 hydroxytryptamine (serotonin) receptor 4 0.044
Chrm1 cholinergic receptor, muscarinic 1, CNS 0.044
Hrk harakiri, BCL2 interacting protein (contains only BH3 domain) 0.044
Kcna4 potassium voltage-gated channel, shaker-related subfamily, member 4 0.043
Kcnq2 potassium voltage-gated channel, subfamily Q, member 2 0.043
Pde6a phosphodiesterase 6A, cGMP-specific, rod, alpha 0.043
Tacr1 tachykinin receptor 1 0.042
Arx aristaless related homeobox 0.042
Npy5r neuropeptide Y receptor Y5 0.042
Slc32a1 solute carrier family 32 (GABA vesicular transporter), member 1 0.042
Cplx1 complexin 1 0.040
Rims1 regulating synaptic membrane exocytosis 1 0.040
Drd2 dopamine receptor D2 0.039
Hes2 hairy and enhancer of split 2 (Drosophila) 0.039
Neurod2 neurogenic differentiation 2 0.039
Tcfap2b transcription factor AP-2 beta 0.039
Gria1 glutamate receptor, ionotropic, AMPA1 (alpha 1) 0.039
Trpc5 transient receptor potential cation channel, subfamily C, member 5 0.038
Tgfb2 transforming growth factor, beta 2 0.038
Rho rhodopsin 0.038
Rit2 Ras-like without CAAX 2 0.037
Wnt7a wingless-related MMTV integration site 7A 0.037
Odz1 odd Oz/ten-m homolog 1 (Drosophila) 0.037
Nrsn1 neurensin 1 0.035
Grik1 glutamate receptor, ionotropic, kainate 1 0.034
Six6 sine oculis-related homeobox 6 homolog (Drosophila) 0.034
Stx1b syntaxin 1B 0.034
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Insrr insulin receptor-related receptor 0.039
Lim2 lens intrinsic membrane protein 2 0.028
Gabra5 gamma-aminobutyric acid (GABA) A receptor, alpha 5 0.020
Htr2c 5-hydroxytryptamine (serotonin) receptor 2C 0.019
Kl Klotho 0.017
Gabrg1 gamma-aminobutyric acid (GABA) A receptor, gamma 1 0.016
Prp15 proline-rich protein 15 0.015
Kcnh7 potassium voltage-gated channel, subfamily H (eag-related), member 7 0.013
Pip5k1c phosphatidylinositol-4-phosphate 5-kinase, type I, gamma 0.013
Arnt2 aryl hydrocarbon receptor nuclear translocator 2 0.012
Ppara peroxisome proliferator activated receptor alpha 0.011
Scn8a sodium channel, voltage gated, type VIII, alpha subunit 0.011
Rgs14 regulator of G-protein signaling 14 0.011
Necab1 N-terminal EF-hand calcium binding protein 1 0.010
Grm6 glutamate receptor, metabotropic 6 0.010
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism