The network for 'positive regulation of defense response to bacterium' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of defense response to bacterium

Any process that activates or increases the frequency, rate or extent of defense response to bacterium.

Homo sapiens
Name Description Probability Func Analog Organism
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.997
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.993
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 0.976
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.859
RELB v-rel reticuloendotheliosis viral oncogene homolog B 0.771
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.750
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 0.673
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 0.469
REL v-rel reticuloendotheliosis viral oncogene homolog (avian) 0.353
TNIP2 TNFAIP3 interacting protein 2 0.295
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.245
MAP3K8 mitogen-activated protein kinase kinase kinase 8 0.220
BCL3 B-cell CLL/lymphoma 3 0.170
CHUK conserved helix-loop-helix ubiquitous kinase 0.112
NLRC4 NLR family, CARD domain containing 4 0.103
MAP3K14 mitogen-activated protein kinase kinase kinase 14 0.096
CRADD CASP2 and RIPK1 domain containing adaptor with death domain 0.044
MALT1 mucosa associated lymphoid tissue lymphoma translocation gene 1 0.043
LRDD leucine-rich repeats and death domain containing 0.028
RIPK2 receptor-interacting serine-threonine kinase 2 0.022
IL18 interleukin 18 (interferon-gamma-inducing factor) 0.015
TAB3 TGF-beta activated kinase 1/MAP3K7 binding protein 3 0.014
SQSTM1 sequestosome 1 0.013
CARD16 caspase recruitment domain family, member 16 0.013
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like 0.011
CAV2 caveolin 2 0.011
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.011
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.010
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
Rel Relish 0.998
PGRP-LC Peptidoglycan recognition protein LC 0.988
AttA Attacin-A 0.986
DptB Diptericin B 0.918
PGRP-SA Peptidoglycan recognition protein SA 0.787
Spn27A Serpin 27A 0.643
Sp7 Serine protease 7 0.642
Mtk Metchnikowin 0.608
grass Gram-positive Specific Serine protease 0.552
imd immune deficiency 0.540
Dredd Death related ced-3/Nedd2-like protein 0.492
PGRP-SD CG7496 gene product from transcript CG7496-RA 0.435
AttC Attacin-C 0.414
ird5 immune response deficient 5 0.302
Irc Immune-regulated catalase 0.289
Spn28D Serpin 28D 0.274
PGRP-SC1a CG14746 gene product from transcript CG14746-RA 0.220
spz spatzle 0.216
BG4 CG12297 gene product from transcript CG12297-RA 0.203
SPE Spatzle-Processing Enzyme 0.174
Mpk2 CG5475 gene product from transcript CG5475-RB 0.158
CG32185 CG32185 gene product from transcript CG32185-RA 0.144
Spn1 Serine protease inhibitor 1 0.121
Drs Drosomycin 0.117
PGRP-SC1b CG8577 gene product from transcript CG8577-RA 0.107
CG7910 CG7910 gene product from transcript CG7910-RA 0.106
pirk poor Imd response upon knock-in 0.106
PGRP-LB Peptidoglycan recognition protein LB 0.086
CG9184 CG9184 gene product from transcript CG9184-RB 0.084
Dpt Diptericin 0.079
CG18594 CG18594 gene product from transcript CG18594-RA 0.075
fon fondue 0.075
ird1 immune response deficient 1 0.074
tna tonalli 0.070
MP1 Melanization Protease 1 0.059
CG15917 CG15917 gene product from transcript CG15917-RA 0.057
PGRP-LF Peptidoglycan recognition protein LF 0.049
Duox Dual oxidase 0.049
IM18 Immune induced molecule 18 0.047
Glt Glutactin 0.046
p38b CG7393 gene product from transcript CG7393-RA 0.046
CG6361 CG6361 gene product from transcript CG6361-RA 0.046
GNBP3 Gram-negative bacteria binding protein 3 0.046
CecC Cecropin C 0.044
CG15065 CG15065 gene product from transcript CG15065-RA 0.043
He Hemese 0.043
CG12766 CG12766 gene product from transcript CG12766-RA 0.041
GNBP1 Gram-negative bacteria binding protein 1 0.038
PGRP-SB1 CG9681 gene product from transcript CG9681-RA 0.037
CG8121 CG8121 gene product from transcript CG8121-RA 0.036
CG42863 CG42863 gene product from transcript CG42863-RB 0.036
CG13422 CG13422 gene product from transcript CG13422-RA 0.035
Iap2 Inhibitor of apoptosis 2 0.035
Myd88 CG2078 gene product from transcript CG2078-RA 0.034
Ark Apaf-1-related-killer 0.030
whd withered 0.030
AGO2 Argonaute 2 0.030
spirit Serine Protease Immune Response Integrator 0.030
upd2 unpaired 2 0.029
bbg big bang 0.028
modSP modular serine protease 0.027
CG18067 CG18067 gene product from transcript CG18067-RA 0.027
Eip71CD Ecdysone-induced protein 28/29kD 0.026
CG13641 CG13641 gene product from transcript CG13641-RA 0.025
Uba2 Smt3 activating enzyme 2 0.024
th thread 0.024
CecA2 Cecropin A2 0.023
eater CG6124 gene product from transcript CG6124-RB 0.023
l(3)mbn lethal (3) malignant blood neoplasm 0.022
kis kismet 0.021
Gadd45 CG11086 gene product from transcript CG11086-RA 0.019
Pvf2 PDGF- and VEGF-related factor 2 0.019
CG4250 CG4250 gene product from transcript CG4250-RA 0.019
spheroide CG9675 gene product from transcript CG9675-RA 0.018
skl sickle 0.018
Idgf2 Imaginal disc growth factor 2 0.018
CG9812 CG9812 gene product from transcript CG9812-RB 0.018
RYBP Ring and YY1 Binding Protein 0.018
TM9SF4 CG7364 gene product from transcript CG7364-RA 0.018
CG7300 CG7300 gene product from transcript CG7300-RC 0.018
Dro Drosocin 0.017
key kenny 0.017
Med Medea 0.016
CG31326 CG31326 gene product from transcript CG31326-RA 0.016
TepIII Thiolester containing protein III 0.016
CG17264 CG17264 gene product from transcript CG17264-RA 0.016
psh persephone 0.016
cact cactus 0.015
CecB Cecropin B 0.015
l(2)08717 lethal (2) 08717 0.015
Toll-7 CG8595 gene product from transcript CG8595-RA 0.015
IM10 Immune induced molecule 10 0.015
CG14567 CG14567 gene product from transcript CG14567-RA 0.015
pie pineapple eye 0.014
Traf4 TNF-receptor-associated factor 4 0.014
Akap200 A kinase anchor protein 200 0.014
Mekk1 CG7717 gene product from transcript CG7717-RB 0.014
Traf6 TNF-receptor-associated factor 6 0.014
CG9631 CG9631 gene product from transcript CG9631-RA 0.014
Trx-2 thioredoxin-2 0.013
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Mus musculus
Name Description Probability Func Analog Organism
Ikbkg inhibitor of kappaB kinase gamma 0.998
Tnf tumor necrosis factor 0.993
Ikbkb inhibitor of kappaB kinase beta 0.990
Casp4 caspase 4, apoptosis-related cysteine peptidase 0.981
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.959
Relb avian reticuloendotheliosis viral (v-rel) oncogene related B 0.918
Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.915
Pycard PYD and CARD domain containing 0.872
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.766
Tcra T-cell receptor alpha chain 0.758
Trp53 transformation related protein 53 0.680
Map3k14 mitogen-activated protein kinase kinase kinase 14 0.677
Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.675
Lyz2 lysozyme 2 0.628
Myd88 myeloid differentiation primary response gene 88 0.469
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 0.376
Il18 interleukin 18 0.335
Gbp5 guanylate binding protein 5 0.313
Fas Fas (TNF receptor superfamily member 6) 0.311
E2f1 E2F transcription factor 1 0.309
Chuk conserved helix-loop-helix ubiquitous kinase 0.247
Igh immunoglobulin heavy chain complex 0.241
Map3k7 mitogen-activated protein kinase kinase kinase 7 0.226
Aim2 absent in melanoma 2 0.216
Il1r1 interleukin 1 receptor, type I 0.178
Traf6 TNF receptor-associated factor 6 0.137
Nlrp3 NLR family, pyrin domain containing 3 0.135
Casp1 caspase 1 0.133
Tlr4 toll-like receptor 4 0.128
Cd44 CD44 antigen 0.121
Ooep oocyte expressed protein homolog (dog) 0.119
Lyn Yamaguchi sarcoma viral (v-yes-1) oncogene homolog 0.116
Cd19 CD19 antigen 0.089
Foxp3 forkhead box P3 0.086
Il7 interleukin 7 0.080
Tax1bp1 Tax1 (human T-cell leukemia virus type I) binding protein 1 0.078
Ikzf1 IKAROS family zinc finger 1 0.067
Il1b interleukin 1 beta 0.065
Bcl3 B-cell leukemia/lymphoma 3 0.063
Card11 caspase recruitment domain family, member 11 0.057
2410004A20Rik RIKEN cDNA 2410004A20 gene 0.057
Mefv Mediterranean fever 0.053
Irf1 interferon regulatory factor 1 0.051
Il10 interleukin 10 0.045
Bcl6 B-cell leukemia/lymphoma 6 0.043
Il2 interleukin 2 0.042
Casp8 caspase 8 0.042
Il6st interleukin 6 signal transducer 0.041
Gbp2 guanylate binding protein 2 0.040
Cd40 CD40 antigen 0.040
Socs1 suppressor of cytokine signaling 1 0.038
Snap23 synaptosomal-associated protein 23 0.038
Tnip1 TNFAIP3 interacting protein 1 0.037
Kat2a K(lysine) acetyltransferase 2A 0.037
Prf1 perforin 1 (pore forming protein) 0.037
Runx1 runt related transcription factor 1 0.034
Ogn osteoglycin 0.033
Cxcl13 chemokine (C-X-C motif) ligand 13 0.032
Nkx2-3 NK2 transcription factor related, locus 3 (Drosophila) 0.031
Csf1 colony stimulating factor 1 (macrophage) 0.031
Cyld cylindromatosis (turban tumor syndrome) 0.031
Nfkbiz nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta 0.029
Map3k8 mitogen-activated protein kinase kinase kinase 8 0.029
Gbp3 guanylate binding protein 3 0.028
Il2rg interleukin 2 receptor, gamma chain 0.028
Nfya nuclear transcription factor-Y alpha 0.028
Ptprc protein tyrosine phosphatase, receptor type, C 0.027
Stk4 serine/threonine kinase 4 0.027
Gm12185 predicted gene 12185 0.026
Rnf31 ring finger protein 31 0.025
Adam17 a disintegrin and metallopeptidase domain 17 0.025
Tnfaip3 tumor necrosis factor, alpha-induced protein 3 0.024
Lta lymphotoxin A 0.023
Stat3 signal transducer and activator of transcription 3 0.022
2010106G01Rik RIKEN cDNA 2010106G01 gene 0.021
Ltbr lymphotoxin B receptor 0.021
Tcf3 transcription factor 3 0.021
Gbp7 guanylate binding protein 7 0.021
Bhlha15 basic helix-loop-helix family, member a15 0.020
Ccr1 chemokine (C-C motif) receptor 1 0.020
Smad1 MAD homolog 1 (Drosophila) 0.020
Id2 inhibitor of DNA binding 2 0.020
Siglece sialic acid binding Ig-like lectin E 0.020
H2afx H2A histone family, member X 0.020
Prpf8 pre-mRNA processing factor 8 0.020
Elavl1 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) 0.019
Abcb4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 0.019
Ctnnb1 catenin (cadherin associated protein), beta 1 0.019
Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 0.019
Prkcd protein kinase C, delta 0.019
Ifi203 interferon activated gene 203 0.018
Dnmt1 DNA methyltransferase (cytosine-5) 1 0.018
Myo7b myosin VIIB 0.018
Ipo9 importin 9 0.018
Skil SKI-like 0.018
1600015I10Rik RIKEN cDNA 1600015I10 gene 0.018
Msgn1 mesogenin 1 0.018
Osmr oncostatin M receptor 0.018
Smad5 MAD homolog 5 (Drosophila) 0.018
Nfkbie nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 0.017
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism