The network for 'regulation of systemic arterial blood pressure by hormone' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of systemic arterial blood pressure by hormone

The process in which hormones modulate the force with which blood passes through the circulatory system. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action.

Name Description Probability Func Analog Organism
Ren1 renin 1 structural 0.991
Agtr1a angiotensin II receptor, type 1a 0.970
Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.944
Klk1b5 kallikrein 1-related peptidase b5 0.929
Lepr leptin receptor 0.666
Slc12a1 solute carrier family 12, member 1 0.662
Klk1b11 kallikrein 1-related peptidase b11 0.660
Serpina1c serine (or cysteine) peptidase inhibitor, clade A, member 1C 0.576
Scn5a sodium channel, voltage-gated, type V, alpha 0.547
Klk1b26 kallikrein 1-related petidase b26 0.464
Umod uromodulin 0.462
Col4a3 collagen, type IV, alpha 3 0.461
Klk1b21 kallikrein 1-related peptidase b21 0.432
F2 coagulation factor II 0.416
Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 0.360
Klk1b27 kallikrein 1-related peptidase b27 0.358
Klk1b8 kallikrein 1-related peptidase b8 0.350
Pcdh12 protocadherin 12 0.273
Klk1 kallikrein 1 0.268
Klk1b16 kallikrein 1-related peptidase b16 0.237
Klk1b4 kallikrein 1-related pepidase b4 0.233
Crp C-reactive protein, pentraxin-related 0.207
Mup4 major urinary protein 4 0.200
Ctrb1 chymotrypsinogen B1 0.197
Vegfa vascular endothelial growth factor A 0.197
Nos3 nitric oxide synthase 3, endothelial cell 0.173
Egfbp2 epidermal growth factor binding protein type B 0.170
Klk1b9 kallikrein 1-related peptidase b9 0.167
Akr1c6 aldo-keto reductase family 1, member C6 0.163
G6pc2 glucose-6-phosphatase, catalytic, 2 0.159
Cpa3 carboxypeptidase A3, mast cell 0.157
Mcpt4 mast cell protease 4 0.145
Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 0.145
Bdkrb2 bradykinin receptor, beta 2 0.140
Try5 trypsin 5 0.140
Tff2 trefoil factor 2 (spasmolytic protein 1) 0.137
Pah phenylalanine hydroxylase 0.132
Clps colipase, pancreatic 0.131
Prss58 protease, serine 58 0.123
Cela2a chymotrypsin-like elastase family, member 2A 0.121
Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 0.120
Klk1b1 kallikrein 1-related peptidase b1 0.115
Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29 0.114
Klk1b3 kallikrein 1-related peptidase b3 0.113
Crim1 cysteine rich transmembrane BMP regulator 1 (chordin like) 0.112
Krt17 keratin 17 0.110
Prss3 protease, serine, 3 0.110
Sprr1b small proline-rich protein 1B 0.109
Pigr polymeric immunoglobulin receptor 0.107
Cma1 chymase 1, mast cell 0.107
Agtr2 angiotensin II receptor, type 2 0.103
Pik3c2g phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide 0.101
Serpina6 serine (or cysteine) peptidase inhibitor, clade A, member 6 0.099
Apcs serum amyloid P-component 0.097
Afm afamin 0.096
Nr0b2 nuclear receptor subfamily 0, group B, member 2 0.095
Klk1b24 kallikrein 1-related peptidase b24 0.094
Ngp neutrophilic granule protein 0.088
Hpd 4-hydroxyphenylpyruvic acid dioxygenase 0.087
Cyp4a14 cytochrome P450, family 4, subfamily a, polypeptide 14 0.085
Gm10334 predicted gene 10334 0.083
Ly6f lymphocyte antigen 6 complex, locus F 0.080
Aqp8 aquaporin 8 0.079
Lhcgr luteinizing hormone/choriogonadotropin receptor 0.078
Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 0.078
Foxa2 forkhead box A2 0.075
F12 coagulation factor XII (Hageman factor) 0.075
Acsm2 acyl-CoA synthetase medium-chain family member 2 0.074
Rhag Rhesus blood group-associated A glycoprotein 0.074
Hsd3b3 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3 0.074
Tjp1 tight junction protein 1 0.074
Alb albumin 0.071
Tm4sf1 transmembrane 4 superfamily member 1 0.071
Serpina1a serine (or cysteine) peptidase inhibitor, clade A, member 1A 0.070
Upp2 uridine phosphorylase 2 0.070
Cyp2c54 cytochrome P450, family 2, subfamily c, polypeptide 54 0.070
Wt1 Wilms tumor 1 homolog 0.069
Retnlb resistin like beta 0.069
2210010C04Rik RIKEN cDNA 2210010C04 gene 0.069
Kcnq1 potassium voltage-gated channel, subfamily Q, member 1 0.068
Zg16 zymogen granule protein 16 0.068
Htr2b 5-hydroxytryptamine (serotonin) receptor 2B 0.067
Adam3 a disintegrin and metallopeptidase domain 3 (cyritestin) 0.066
Kcne1 potassium voltage-gated channel, Isk-related subfamily, member 1 0.065
Hgd homogentisate 1, 2-dioxygenase 0.063
Cps1 carbamoyl-phosphate synthetase 1 0.062
Krtap6-1 keratin associated protein 6-1 0.060
F9 coagulation factor IX 0.059
Tg thyroglobulin 0.059
Sprr2i small proline-rich protein 2I 0.059
Ptgs2 prostaglandin-endoperoxide synthase 2 0.058
Apoh apolipoprotein H 0.057
Wnk4 WNK lysine deficient protein kinase 4 0.056
Rnase1 ribonuclease, RNase A family, 1 (pancreatic) 0.056
Sprr2h small proline-rich protein 2H 0.053
Kel Kell blood group 0.052
Cckar cholecystokinin A receptor 0.051
Fshb follicle stimulating hormone beta 0.051
Ctsb cathepsin B 0.050
Ccl22 chemokine (C-C motif) ligand 22 0.050
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
NOSTRIN nitric oxide synthase trafficker 0.829
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.730
PAX8 paired box 8 0.391
VAC14 Vac14 homolog (S. cerevisiae) 0.382
HSPB1 heat shock 27kDa protein 1 0.175
PSAP prosaposin 0.173
CTSA cathepsin A 0.171
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 0.117
CAV2 caveolin 2 0.071
TIMP3 TIMP metallopeptidase inhibitor 3 0.061
LAMP1 lysosomal-associated membrane protein 1 0.059
TUBB8 tubulin, beta 8 0.044
GRN granulin 0.042
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.039
GNS glucosamine (N-acetyl)-6-sulfatase 0.039
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase 0.036
PGD phosphogluconate dehydrogenase 0.033
CTSB cathepsin B 0.030
CD164 CD164 molecule, sialomucin 0.029
CST3 cystatin C 0.029
TKT transketolase 0.026
ITM2B integral membrane protein 2B 0.026
WFDC2 WAP four-disulfide core domain 2 0.025
BDKRB2 bradykinin receptor B2 0.025
SLC9A3 solute carrier family 9 (sodium/hydrogen exchanger), member 3 0.024
MUC4 mucin 4, cell surface associated 0.023
PIGR polymeric immunoglobulin receptor 0.021
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase) 0.020
GLP1R glucagon-like peptide 1 receptor 0.017
PLD3 phospholipase D family, member 3 0.017
KCTD15 potassium channel tetramerisation domain containing 15 0.017
CAV1 caveolin 1, caveolae protein, 22kDa 0.017
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) 0.016
ST14 suppression of tumorigenicity 14 (colon carcinoma) 0.016
APLP2 amyloid beta (A4) precursor-like protein 2 0.016
NEU1 sialidase 1 (lysosomal sialidase) 0.016
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 0.015
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1 0.014
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c 0.014
PRKCE protein kinase C, epsilon 0.014
PRR15L proline rich 15-like 0.013
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1 0.013
GUCY2C guanylate cyclase 2C (heat stable enterotoxin receptor) 0.013
LAMP2 lysosomal-associated membrane protein 2 0.013
CRYAB crystallin, alpha B 0.012
NUCB1 nucleobindin 1 0.012
TPP1 tripeptidyl peptidase I 0.012
XDH xanthine dehydrogenase 0.012
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.012
TM4SF5 transmembrane 4 L six family member 5 0.012
LAPTM4A lysosomal protein transmembrane 4 alpha 0.011
POR P450 (cytochrome) oxidoreductase 0.011
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 0.011
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 0.011
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 0.011
TAC1 tachykinin, precursor 1 0.011
CDX1 caudal type homeobox 1 0.011
GAA glucosidase, alpha; acid 0.011
ACAN aggrecan 0.011
EDNRB endothelin receptor type B 0.011
PLG plasminogen 0.011
TMPRSS2 transmembrane protease, serine 2 0.011
TIMP2 TIMP metallopeptidase inhibitor 2 0.011
VTN vitronectin 0.011
SLC44A4 solute carrier family 44, member 4 0.010
FXYD3 FXYD domain containing ion transport regulator 3 0.010
GJB1 gap junction protein, beta 1, 32kDa 0.010
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Rattus norvegicus
Name Description Probability Func Analog Organism
Ahsg alpha-2-HS-glycoprotein 0.013
Olr287 olfactory receptor 287 0.011
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism