Process View
The network for 'regulation of systemic arterial blood pressure by hormone' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
The process in which hormones modulate the force with which blood passes through the circulatory system. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action.
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
Ren1 | renin 1 structural | 0.991 | |
Agtr1a | angiotensin II receptor, type 1a | 0.970 | |
Agt | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 0.944 | |
Klk1b5 | kallikrein 1-related peptidase b5 | 0.929 | |
Lepr | leptin receptor | 0.666 | |
Slc12a1 | solute carrier family 12, member 1 | 0.662 | |
Klk1b11 | kallikrein 1-related peptidase b11 | 0.660 | |
Serpina1c | serine (or cysteine) peptidase inhibitor, clade A, member 1C | 0.576 | |
Scn5a | sodium channel, voltage-gated, type V, alpha | 0.547 | |
Klk1b26 | kallikrein 1-related petidase b26 | 0.464 | |
Umod | uromodulin | 0.462 | |
Col4a3 | collagen, type IV, alpha 3 | 0.461 | |
Klk1b21 | kallikrein 1-related peptidase b21 | 0.432 | |
F2 | coagulation factor II | 0.416 | |
Ace | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 | 0.360 | |
Klk1b27 | kallikrein 1-related peptidase b27 | 0.358 | |
Klk1b8 | kallikrein 1-related peptidase b8 | 0.350 | |
Pcdh12 | protocadherin 12 | 0.273 | |
Klk1 | kallikrein 1 | 0.268 | |
Klk1b16 | kallikrein 1-related peptidase b16 | 0.237 | |
Klk1b4 | kallikrein 1-related pepidase b4 | 0.233 | |
Crp | C-reactive protein, pentraxin-related | 0.207 | |
Mup4 | major urinary protein 4 | 0.200 | |
Ctrb1 | chymotrypsinogen B1 | 0.197 | |
Vegfa | vascular endothelial growth factor A | 0.197 | |
Nos3 | nitric oxide synthase 3, endothelial cell | 0.173 | |
Egfbp2 | epidermal growth factor binding protein type B | 0.170 | |
Klk1b9 | kallikrein 1-related peptidase b9 | 0.167 | |
Akr1c6 | aldo-keto reductase family 1, member C6 | 0.163 | |
G6pc2 | glucose-6-phosphatase, catalytic, 2 | 0.159 | |
Cpa3 | carboxypeptidase A3, mast cell | 0.157 | |
Mcpt4 | mast cell protease 4 | 0.145 | |
Cyp3a11 | cytochrome P450, family 3, subfamily a, polypeptide 11 | 0.145 | |
Bdkrb2 | bradykinin receptor, beta 2 | 0.140 | |
Try5 | trypsin 5 | 0.140 | |
Tff2 | trefoil factor 2 (spasmolytic protein 1) | 0.137 | |
Pah | phenylalanine hydroxylase | 0.132 | |
Clps | colipase, pancreatic | 0.131 | |
Prss58 | protease, serine 58 | 0.123 | |
Cela2a | chymotrypsin-like elastase family, member 2A | 0.121 | |
Cyp2e1 | cytochrome P450, family 2, subfamily e, polypeptide 1 | 0.120 | |
Klk1b1 | kallikrein 1-related peptidase b1 | 0.115 | |
Cyp2c29 | cytochrome P450, family 2, subfamily c, polypeptide 29 | 0.114 | |
Klk1b3 | kallikrein 1-related peptidase b3 | 0.113 | |
Crim1 | cysteine rich transmembrane BMP regulator 1 (chordin like) | 0.112 | |
Krt17 | keratin 17 | 0.110 | |
Prss3 | protease, serine, 3 | 0.110 | |
Sprr1b | small proline-rich protein 1B | 0.109 | |
Pigr | polymeric immunoglobulin receptor | 0.107 | |
Cma1 | chymase 1, mast cell | 0.107 | |
Agtr2 | angiotensin II receptor, type 2 | 0.103 | |
Pik3c2g | phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide | 0.101 | |
Serpina6 | serine (or cysteine) peptidase inhibitor, clade A, member 6 | 0.099 | |
Apcs | serum amyloid P-component | 0.097 | |
Afm | afamin | 0.096 | |
Nr0b2 | nuclear receptor subfamily 0, group B, member 2 | 0.095 | |
Klk1b24 | kallikrein 1-related peptidase b24 | 0.094 | |
Ngp | neutrophilic granule protein | 0.088 | |
Hpd | 4-hydroxyphenylpyruvic acid dioxygenase | 0.087 | |
Cyp4a14 | cytochrome P450, family 4, subfamily a, polypeptide 14 | 0.085 | |
Gm10334 | predicted gene 10334 | 0.083 | |
Ly6f | lymphocyte antigen 6 complex, locus F | 0.080 | |
Aqp8 | aquaporin 8 | 0.079 | |
Lhcgr | luteinizing hormone/choriogonadotropin receptor | 0.078 | |
Cyp1a2 | cytochrome P450, family 1, subfamily a, polypeptide 2 | 0.078 | |
Foxa2 | forkhead box A2 | 0.075 | |
F12 | coagulation factor XII (Hageman factor) | 0.075 | |
Acsm2 | acyl-CoA synthetase medium-chain family member 2 | 0.074 | |
Rhag | Rhesus blood group-associated A glycoprotein | 0.074 | |
Hsd3b3 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3 | 0.074 | |
Tjp1 | tight junction protein 1 | 0.074 | |
Alb | albumin | 0.071 | |
Tm4sf1 | transmembrane 4 superfamily member 1 | 0.071 | |
Serpina1a | serine (or cysteine) peptidase inhibitor, clade A, member 1A | 0.070 | |
Upp2 | uridine phosphorylase 2 | 0.070 | |
Cyp2c54 | cytochrome P450, family 2, subfamily c, polypeptide 54 | 0.070 | |
Wt1 | Wilms tumor 1 homolog | 0.069 | |
Retnlb | resistin like beta | 0.069 | |
2210010C04Rik | RIKEN cDNA 2210010C04 gene | 0.069 | |
Kcnq1 | potassium voltage-gated channel, subfamily Q, member 1 | 0.068 | |
Zg16 | zymogen granule protein 16 | 0.068 | |
Htr2b | 5-hydroxytryptamine (serotonin) receptor 2B | 0.067 | |
Adam3 | a disintegrin and metallopeptidase domain 3 (cyritestin) | 0.066 | |
Kcne1 | potassium voltage-gated channel, Isk-related subfamily, member 1 | 0.065 | |
Hgd | homogentisate 1, 2-dioxygenase | 0.063 | |
Cps1 | carbamoyl-phosphate synthetase 1 | 0.062 | |
Krtap6-1 | keratin associated protein 6-1 | 0.060 | |
F9 | coagulation factor IX | 0.059 | |
Tg | thyroglobulin | 0.059 | |
Sprr2i | small proline-rich protein 2I | 0.059 | |
Ptgs2 | prostaglandin-endoperoxide synthase 2 | 0.058 | |
Apoh | apolipoprotein H | 0.057 | |
Wnk4 | WNK lysine deficient protein kinase 4 | 0.056 | |
Rnase1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.056 | |
Sprr2h | small proline-rich protein 2H | 0.053 | |
Kel | Kell blood group | 0.052 | |
Cckar | cholecystokinin A receptor | 0.051 | |
Fshb | follicle stimulating hormone beta | 0.051 | |
Ctsb | cathepsin B | 0.050 | |
Ccl22 | chemokine (C-C motif) ligand 22 | 0.050 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
NOSTRIN | nitric oxide synthase trafficker | 0.829 | |
MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.730 | |
PAX8 | paired box 8 | 0.391 | |
VAC14 | Vac14 homolog (S. cerevisiae) | 0.382 | |
HSPB1 | heat shock 27kDa protein 1 | 0.175 | |
PSAP | prosaposin | 0.173 | |
CTSA | cathepsin A | 0.171 | |
ATP6AP1 | ATPase, H+ transporting, lysosomal accessory protein 1 | 0.117 | |
CAV2 | caveolin 2 | 0.071 | |
TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.061 | |
LAMP1 | lysosomal-associated membrane protein 1 | 0.059 | |
TUBB8 | tubulin, beta 8 | 0.044 | |
GRN | granulin | 0.042 | |
AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 0.039 | |
GNS | glucosamine (N-acetyl)-6-sulfatase | 0.039 | |
MTHFD1 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | 0.036 | |
PGD | phosphogluconate dehydrogenase | 0.033 | |
CTSB | cathepsin B | 0.030 | |
CD164 | CD164 molecule, sialomucin | 0.029 | |
CST3 | cystatin C | 0.029 | |
TKT | transketolase | 0.026 | |
ITM2B | integral membrane protein 2B | 0.026 | |
WFDC2 | WAP four-disulfide core domain 2 | 0.025 | |
BDKRB2 | bradykinin receptor B2 | 0.025 | |
SLC9A3 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 | 0.024 | |
MUC4 | mucin 4, cell surface associated | 0.023 | |
PIGR | polymeric immunoglobulin receptor | 0.021 | |
FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) | 0.020 | |
GLP1R | glucagon-like peptide 1 receptor | 0.017 | |
PLD3 | phospholipase D family, member 3 | 0.017 | |
KCTD15 | potassium channel tetramerisation domain containing 15 | 0.017 | |
CAV1 | caveolin 1, caveolae protein, 22kDa | 0.017 | |
GRINA | glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) | 0.016 | |
ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.016 | |
APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.016 | |
NEU1 | sialidase 1 (lysosomal sialidase) | 0.016 | |
GABRG2 | gamma-aminobutyric acid (GABA) A receptor, gamma 2 | 0.015 | |
FOLH1 | folate hydrolase (prostate-specific membrane antigen) 1 | 0.014 | |
ATP6V0C | ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c | 0.014 | |
PRKCE | protein kinase C, epsilon | 0.014 | |
PRR15L | proline rich 15-like | 0.013 | |
SLC5A1 | solute carrier family 5 (sodium/glucose cotransporter), member 1 | 0.013 | |
GUCY2C | guanylate cyclase 2C (heat stable enterotoxin receptor) | 0.013 | |
LAMP2 | lysosomal-associated membrane protein 2 | 0.013 | |
CRYAB | crystallin, alpha B | 0.012 | |
NUCB1 | nucleobindin 1 | 0.012 | |
TPP1 | tripeptidyl peptidase I | 0.012 | |
XDH | xanthine dehydrogenase | 0.012 | |
CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.012 | |
TM4SF5 | transmembrane 4 L six family member 5 | 0.012 | |
LAPTM4A | lysosomal protein transmembrane 4 alpha | 0.011 | |
POR | P450 (cytochrome) oxidoreductase | 0.011 | |
CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 | 0.011 | |
ASAH1 | N-acylsphingosine amidohydrolase (acid ceramidase) 1 | 0.011 | |
ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.011 | |
TAC1 | tachykinin, precursor 1 | 0.011 | |
CDX1 | caudal type homeobox 1 | 0.011 | |
GAA | glucosidase, alpha; acid | 0.011 | |
ACAN | aggrecan | 0.011 | |
EDNRB | endothelin receptor type B | 0.011 | |
PLG | plasminogen | 0.011 | |
TMPRSS2 | transmembrane protease, serine 2 | 0.011 | |
TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.011 | |
VTN | vitronectin | 0.011 | |
SLC44A4 | solute carrier family 44, member 4 | 0.010 | |
FXYD3 | FXYD domain containing ion transport regulator 3 | 0.010 | |
GJB1 | gap junction protein, beta 1, 32kDa | 0.010 |