The network for 'folic acid containing compound metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

folic acid containing compound metabolic process

The chemical reactions and pathways involving a folic acid-containing compound, i.e. any of a group of heterocyclic compounds based on the pteroic acid skeleton conjugated with one or more L-glutamic acid or L-glutamate units.

Mus musculus
Name Description Probability Func Analog Organism
Asns asparagine synthetase 0.782
Slc11a2 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 0.694
Psat1 phosphoserine aminotransferase 1 0.450
Hpd 4-hydroxyphenylpyruvic acid dioxygenase 0.298
Aldh18a1 aldehyde dehydrogenase 18 family, member A1 0.296
Slc7a5 solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 0.290
Slc26a1 solute carrier family 26 (sulfate transporter), member 1 0.267
Klf1 Kruppel-like factor 1 (erythroid) 0.250
Nars asparaginyl-tRNA synthetase 0.245
Shmt2 serine hydroxymethyltransferase 2 (mitochondrial) 0.219
F13b coagulation factor XIII, beta subunit 0.177
Gars glycyl-tRNA synthetase 0.165
Slc6a13 solute carrier family 6 (neurotransmitter transporter, GABA), member 13 0.153
Hnf4a hepatic nuclear factor 4, alpha 0.138
Slc40a1 solute carrier family 40 (iron-regulated transporter), member 1 0.131
Timd2 T-cell immunoglobulin and mucin domain containing 2 0.130
Apom apolipoprotein M 0.121
Abcc6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 0.113
Hsd3b4 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 4 0.102
Gjb1 gap junction protein, beta 1 0.093
Pipox pipecolic acid oxidase 0.085
Hgd homogentisate 1, 2-dioxygenase 0.079
Nr1h4 nuclear receptor subfamily 1, group H, member 4 0.079
Ppat phosphoribosyl pyrophosphate amidotransferase 0.078
BC048355 cDNA sequence BC048355 0.072
Apoc1 apolipoprotein C-I 0.070
Iars isoleucine-tRNA synthetase 0.069
Bhmt2 betaine-homocysteine methyltransferase 2 0.068
Tmem48 transmembrane protein 48 0.067
Lrp2 low density lipoprotein receptor-related protein 2 0.067
Ung uracil DNA glycosylase 0.066
Serpina6 serine (or cysteine) peptidase inhibitor, clade A, member 6 0.064
Clcn2 chloride channel 2 0.063
Cyp2d26 cytochrome P450, family 2, subfamily d, polypeptide 26 0.063
Aadat aminoadipate aminotransferase 0.062
Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.061
Gcgr glucagon receptor 0.054
Sdsl serine dehydratase-like 0.050
Slc16a2 solute carrier family 16 (monocarboxylic acid transporters), member 2 0.050
Yars tyrosyl-tRNA synthetase 0.049
Prkar2a protein kinase, cAMP dependent regulatory, type II alpha 0.049
Gldc glycine decarboxylase 0.046
Cyp2d10 cytochrome P450, family 2, subfamily d, polypeptide 10 0.045
Kng1 kininogen 1 0.044
Car5a carbonic anhydrase 5a, mitochondrial 0.043
Cldn2 claudin 2 0.042
1300017J02Rik RIKEN cDNA 1300017J02 gene 0.042
Prodh2 proline dehydrogenase (oxidase) 2 0.041
F2 coagulation factor II 0.040
Umps uridine monophosphate synthetase 0.039
Proc protein C 0.038
Mpzl2 myelin protein zero-like 2 0.038
Masp2 mannan-binding lectin serine peptidase 2 0.037
Slc22a2 solute carrier family 22 (organic cation transporter), member 2 0.037
Ppara peroxisome proliferator activated receptor alpha 0.037
Slc7a1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 0.037
Serpinf2 serine (or cysteine) peptidase inhibitor, clade F, member 2 0.037
Slc2a2 solute carrier family 2 (facilitated glucose transporter), member 2 0.036
Ero1l ERO1-like (S. cerevisiae) 0.035
Slc12a1 solute carrier family 12, member 1 0.035
Dmgdh dimethylglycine dehydrogenase precursor 0.035
Plg plasminogen 0.034
Acy1 aminoacylase 1 0.033
Pycr1 pyrroline-5-carboxylate reductase 1 0.033
Sall1 sal-like 1 (Drosophila) 0.032
Itih1 inter-alpha trypsin inhibitor, heavy chain 1 0.032
Gamt guanidinoacetate methyltransferase 0.032
G6pc glucose-6-phosphatase, catalytic 0.032
F7 coagulation factor VII 0.032
Ctps cytidine 5'-triphosphate synthase 0.032
Orc2 origin recognition complex, subunit 2 0.031
Cyp2a12 cytochrome P450, family 2, subfamily a, polypeptide 12 0.031
Gc group specific component 0.030
Onecut1 one cut domain, family member 1 0.029
Rad51 RAD51 homolog (S. cerevisiae) 0.029
Cldn1 claudin 1 0.029
Fpgs folylpolyglutamyl synthetase 0.029
Cideb cell death-inducing DNA fragmentation factor, alpha subunit-like effector B 0.029
Lars leucyl-tRNA synthetase 0.029
Exo1 exonuclease 1 0.029
Mgmt O-6-methylguanine-DNA methyltransferase 0.028
Hsd3b6 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6 0.027
Slc6a12 solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12 0.026
Serpina1c serine (or cysteine) peptidase inhibitor, clade A, member 1C 0.026
Lama1 laminin, alpha 1 0.025
Upp2 uridine phosphorylase 2 0.025
Iyd iodotyrosine deiodinase 0.025
Tdo2 tryptophan 2,3-dioxygenase 0.024
Phgdh 3-phosphoglycerate dehydrogenase 0.024
Ttr transthyretin 0.024
Orc1 origin recognition complex, subunit 1 0.024
Mcm10 minichromosome maintenance deficient 10 (S. cerevisiae) 0.024
Lhx1 LIM homeobox protein 1 0.024
Cdc6 cell division cycle 6 homolog (S. cerevisiae) 0.024
Pde6b phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide 0.023
Gnmt glycine N-methyltransferase 0.023
Slc3a1 solute carrier family 3, member 1 0.023
Aldob aldolase B, fructose-bisphosphate 0.023
Apoa2 apolipoprotein A-II 0.023
Clcnka chloride channel Ka 0.023
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
pycard PYD and CARD domain containing 0.016
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
YARS tyrosyl-tRNA synthetase 0.073
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Rattus norvegicus
Name Description Probability Func Analog Organism
Rnaseh2b ribonuclease H2, subunit B 0.346
Ahcy adenosylhomocysteinase 0.297
Pcdhga11 protocadherin gamma subfamily A, 11 0.102
Kmo kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) 0.095
Hfe hemochromatosis 0.092
Bmp7 bone morphogenetic protein 7 0.092
Casp6 caspase 6 0.092
Parp1 poly (ADP-ribose) polymerase 1 0.091
Shmt2 serine hydroxymethyltransferase 2 (mitochondrial) 0.088
Nde1 nudE nuclear distribution gene E homolog 1 (A. nidulans) 0.083
Pctp phosphatidylcholine transfer protein 0.080
Slc25a13 solute carrier family 25, member 13 (citrin) 0.076
Ung uracil-DNA glycosylase 0.075
Wdr77 WD repeat domain 77 0.059
Polr1b polymerase (RNA) I polypeptide B 0.056
Sf3b3 splicing factor 3b, subunit 3 0.053
Msh2 mutS homolog 2 (E. coli) 0.052
Olr1701 olfactory receptor 1701 0.051
Hn1l hematological and neurological expressed 1-like 0.051
Mlh1 mutL homolog 1 (E. coli) 0.049
Hnf1a HNF1 homeobox A 0.045
Casp7 caspase 7 0.045
Srpr signal recognition particle receptor ('docking protein') 0.044
Aldh18a1 aldehyde dehydrogenase 18 family, member A1 0.040
Gspt1 G1 to S phase transition 1 0.040
Nolc1 nucleolar and coiled-body phosphoprotein 1 0.038
Acsm3 acyl-CoA synthetase medium-chain family member 3 0.037
Proc protein C 0.035
Cyp2c23 cytochrome P450, family 2, subfamily c, polypeptide 23 0.033
Tyms thymidylate synthetase 0.032
Rad51c Rad51 homolog c (S. cerevisiae) 0.031
Sardh sarcosine dehydrogenase 0.031
Creb1 cAMP responsive element binding protein 1 0.030
LOC259245 alpha-2u globulin PGCL5 0.029
Dhfr dihydrofolate reductase 0.028
Rbp2 retinol binding protein 2, cellular 0.028
Rpa2 replication protein A2 0.028
Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 0.028
Fas Fas (TNF receptor superfamily, member 6) 0.028
Prim2 primase, DNA, polypeptide 2 0.028
Afp alpha-fetoprotein 0.028
Clptm1l CLPTM1-like 0.027
Agps alkylglycerone phosphate synthase 0.026
Dio1 deiodinase, iodothyronine, type I 0.025
Hspb2 heat shock protein beta 2 0.025
Brca1 breast cancer 1 0.025
Pck1 phosphoenolpyruvate carboxykinase 1 (soluble) 0.023
Cyp2d2 cytochrome P450, family 2, subfamily d, polypeptide 2 0.023
Rassf9 Ras association (RalGDS/AF-6) domain family (N-terminal) member 9 0.022
Ces1c carboxylesterase 1C 0.022
Shmt1 serine hydroxymethyltransferase 1 (soluble) 0.022
Slc17a1 solute carrier family 17 (sodium phosphate), member 1 0.021
Pola1 polymerase (DNA directed), alpha 1 0.021
Ccne1 cyclin E1 0.021
Rgn regucalcin (senescence marker protein-30) 0.021
Akr1c14 aldo-keto reductase family 1, member C14 0.020
Mthfd1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase 0.020
Timeless timeless homolog (Drosophila) 0.020
Chek1 CHK1 checkpoint homolog (S. pombe) 0.020
RGD1305274 similar to RIKEN cDNA 2010305A19 0.020
Foxm1 forkhead box M1 0.019
Srm spermidine synthase 0.019
Sec61a1 Sec61 alpha 1 subunit (S. cerevisiae) 0.019
Gulo gulonolactone (L-) oxidase 0.019
Mipep mitochondrial intermediate peptidase 0.018
Tmem185b transmembrane protein 185B 0.018
F10 coagulation factor X 0.017
Soat1 sterol O-acyltransferase 1 0.017
Psmc3ip PSMC3 interacting protein 0.017
Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 0.017
Mgst2 microsomal glutathione S-transferase 2 0.016
Acvr1b activin A receptor, type IB 0.016
Tk1 thymidine kinase 1, soluble 0.016
Aldh6a1 aldehyde dehydrogenase 6 family, member A1 0.016
Enpp3 ectonucleotide pyrophosphatase/phosphodiesterase 3 0.015
Fabp1 fatty acid binding protein 1, liver 0.015
Slc30a7 solute carrier family 30 (zinc transporter), member 7 0.015
Emd emerin 0.015
Ppp1r3b protein phosphatase 1, regulatory (inhibitor) subunit 3B 0.015
Mybbp1a MYB binding protein (P160) 1a 0.015
Slco2a1 solute carrier organic anion transporter family, member 2a1 0.014
Polr3b polymerase (RNA) III (DNA directed) polypeptide B 0.014
Aqp9 aquaporin 9 0.014
Anp32b acidic (leucine-rich) nuclear phosphoprotein 32 family, member B 0.014
Gc group specific component 0.014
Ddx54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 0.014
Dph1 DPH1 homolog (S. cerevisiae) 0.014
Cenpi centromere protein I 0.014
Tmpo thymopoietin 0.014
Gcs1 glucosidase 1 0.014
Fert2 fer (fms/fps related) protein kinase, testis specific 2 0.013
Aldh4a1 aldehyde dehydrogenase 4 family, member A1 0.013
Atxn3 ataxin 3 0.013
Pold3 polymerase (DNA-directed), delta 3, accessory subunit 0.013
Gcgr glucagon receptor 0.013
Fdxr ferredoxin reductase 0.013
Agxt2 alanine-glyoxylate aminotransferase 2 0.013
Irf2 interferon regulatory factor 2 0.013
Slc19a1 solute carrier family 19 (folate transporter), member 1 0.012
Rcc2 regulator of chromosome condensation 2 0.012
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism